DOI: 10.1016/s0006-8993(99)02095-8. Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury

Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury

10.1016/s0006-8993(99)02095-8

Crossref journal-article

Elsevier BV

Brain Research (78)

Bibliography

Suh, S. W., Chen, J. W., Motamedi, M., Brent Bell, Listiak, K., Pons, N. F., Danscher, G., & Frederickson, C. J. (2000). Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury. Brain Research, 852(2), 268â273.

Authors 8

Sang Won Suh (first)
Jefferson W. Chen (additional)
Massoud Motamedi (additional)
Brent Bell (additional)
Kathy Listiak (additional)
Neus F. Pons (additional)
Gorm Danscher (additional)
Christopher J. Frederickson (additional)

References 42 Referenced 250

10.1016/0006-8993(87)91355-2 / Brain Res. / Selective release of endogenous zinc from the hippocampal mossy fibers in situ by Aniksztejn (1987)
10.1038/308734a0 / Nature / Release of endogenous Zn2+ from brain tissue during activity by Assaf (1984)
10.1097/00001756-199210000-00010 / NeuroReport / Enrichment of glutamate in zinc-containing terminals of the cat visual cortex by Beaulieu (1992)
10.1111/j.1749-6632.1995.tb16586.x / Ann. N.Y. Acad. Sci. / Evidence for prolonged release of excitatory amino acids in severe human head trauma. Relationship to clinical events by Bullock (1995)
10.1046/j.1471-4159.1998.71062401.x / J. Neurochem. / Calcium-sensitive fluorescent dyes can report increases in intracellular free zinc concentration in cultured forebrain neurons by Cheng (1998)
10.1146/annurev.neuro.21.1.347 / Annu. Rev. Neurosci. / Zinc and brain injury by Choi (1998)
10.1089/neu.1994.11.499 / J. Neurotraumatol. / Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models by Clark (1994)
10.1097/00001756-199605170-00017 / NeuroReport / Prevention of zinc neurotoxicity in vivo by N,N,N′,N′-tetrakis (2-pyridylmethyl) ethylene-diamine (TPEN) by Cuajungco (1996)
10.1177/002215549704501107 / J. Histochem. Cytochem. / Autometallographic silver enhancement of zinc sulfide crystals created in cryostat sections from human brain biopsies: a new technique that makes it feasible to demonstrate zinc ions in tissue sections from biopsies and early autopsy material by Danscher (1997)
10.1007/BF02331399 / J. Histochem. / The autometallographic zinc-sulphide method. A new approach involving in vivo creation of nanometer-sized zinc sulphide crystal lattices in zinc-enriched synaptic and secretory vesicles by Danscher (1996)
10.1126/science.2567056 / Science / The role of excitatory amino acids and NMDA receptors in traumatic brain injury by Faden (1989)
10.1016/0006-8993(89)90199-6 / Brain Res. / Translocation of zinc may contribute to seizure-induced death of neurons by Frederickson (1989)
10.1016/0165-0270(87)90042-2 / J. Neurosci. Meth. / A quinoline fluorescence method for visualizing and assaying the histochemically reactive zinc (bouton zinc) in the brain by Frederickson (1987)
10.1016/S0074-7742(08)60279-2 / Int. Rev. Neurobiol. / Neurobiology of zinc and zinc-containing neurons by Frederickson (1989)
{'key': '10.1016/S0006-8993(99)02095-8_BIB15', 'first-page': '234', 'article-title': 'Temperature dependent release and translocation of zinc in hippocampus in vitro and in vivo', 'volume': '24', 'author': 'Frederickson', 'year': '1998', 'journal-title': 'Soc. Neurosci. Abstr.'} / Soc. Neurosci. Abstr. / Temperature dependent release and translocation of zinc in hippocampus in vitro and in vivo by Frederickson (1998)
10.1038/308736a0 / Nature / Stimulation-induced uptake and release of zinc in hippocampal slices by Howell (1984)
10.1046/j.1460-9568.1999.00437.x / Eur. J. Neurosci. / Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures by Kim (1999)
10.1016/S0306-4522(98)00313-3 / Neuroscience / Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals by Kim (1999)
10.1523/JNEUROSCI.08-06-02164.1988 / J. Neurosci. / Zinc alters excitatory amino acid neurotoxicity on cortical neurons by Koh (1988)
10.1126/science.272.5264.1013 / Science / The role of zinc in selective neuronal death after transient global cerebral ischemia by Koh (1996)
10.1523/JNEUROSCI.12-12-04846.1992 / J. Neurosci. / Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus by Lowenstein (1992)
10.1016/0892-0362(93)90012-D / Neurotoxicol. Teratol. / Proconvulsant action of diethyldithiocarbamate in stimulation of the perforant path by Mitchell (1993)
10.1111/j.1528-1167.1990.tb06298.x / Epilepsia / Effects of subcutaneous injections of zinc chloride on seizures induced by noise and by kainic acid by Morton (1990)
10.1038/jcbfm.1993.22 / J. Cereb. Blood Flow Metab. / Regional changes in interstitial K+ and Ca2+ levels following cortical compression contusion trauma in rats by Nilsson (1993)
10.1073/pnas.93.25.14934 / Proc. Natl. Acad. Sci. U.S.A. / ZnT-3, a putative transporter of zinc into synaptic vesicles by Palmiter (1996)
10.1046/j.1471-4159.1999.0730450.x / J. Neurochem. / Induction of an immediate early gene egr-1 by zinc through extracellular signal-regulated kinase activation in cortical culture: its role in zinc-induced neuronal death by Park (1999)
D.D. Perrin, Stability Constants of Metal–Ion Complexes: Organic Ligands, Pergamon, Oxford, 1979, pp. 399–405.
10.1126/science.2883728 / Science / Zinc selectively blocks the action of N-methyl-d-aspartate on cortical neurons by Peters (1987)
10.1523/JNEUROSCI.17-24-09554.1997 / J. Neurosci. / Measurement of intracellular free zinc in living cortical neurons: routes of entry by Sensi (1997)
10.1073/pnas.96.5.2414 / Proc. Natl. Acad. Sci. U.S.A. / Preferential Zn2+ influx through Ca2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production by Sensi (1999)
10.1126/science.6093256 / Science / Blockade of N-methyl-d-aspartate receptors may protect against ischemic damage in the brain by Simon (1984)
10.1016/0006-8993(85)90017-4 / Brain Res. / A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation by Sloviter (1985)
10.1016/S0006-8993(98)00943-3 / Brain Res. / Rapid disappearance of zinc positive terminals in focal brain ischemia by Sorensen (1998)
10.1016/0006-8993(76)90577-1 / Brain Res. / Antagonism of cortical excitation of striatal neurons by glutamic acid diethylester: evidence for glutamic acid as an excitatory transmitter in the rat striatum by Spencer (1976)
W. Spielmeyer, Histopathologie des Nerven Systems, Springer, Berlin, 1922, pp. 74–79. Original not seen: Cited in: Simon et al., Science, 226 (1984) 850–852.
{'key': '10.1016/S0006-8993(99)02095-8_BIB36', 'first-page': '2101', 'article-title': 'Extracellular zinc mediates selective neuronal death in hippocampus and amygdala following kainate-induced seizure', 'volume': '22', 'author': 'Suh', 'year': '1996', 'journal-title': 'Soc. Neurosci. Abstr.'} / Soc. Neurosci. Abstr. / Extracellular zinc mediates selective neuronal death in hippocampus and amygdala following kainate-induced seizure by Suh (1996)
10.1177/002215549904700715 / J. Histochem. Cytochem. / Detection of pathological zinc accumulation in neurons: methods for autopsy, biopsy and cultured tissue by Suh (1999)
10.1006/abio.1995.1260 / Anal. Biochem. / Lifetime-based fluorescence energy transfer biosensing of zinc by Thompson (1995)
10.1016/0304-3940(90)90002-Q / Neurosci. Lett. / Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat by Tonder (1990)
10.1038/328640a0 / Nature / Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons by Westbrook (1987)
10.1016/S0006-8993(97)01208-0 / Brain. Res. / Kainate-stimulated Zn2+ uptake labels cortical neurons with Ca2+-permeable AMPA/kainate channels by Yin (1998)
10.1097/00001756-199512150-00025 / NeuroReport / Zn(2+) permeates Ca(2+) permeable AMPA/kainate channels and triggers selective neural injury by Yin (1995)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 1:48 p.m.)
Deposited	5 years, 7 months ago (Jan. 28, 2020, 8 a.m.)
Indexed	1 month, 3 weeks ago (July 11, 2025, 9:13 p.m.)
Issued	25 years, 8 months ago (Jan. 1, 2000)
Published	25 years, 8 months ago (Jan. 1, 2000)
Published Print	25 years, 8 months ago (Jan. 1, 2000)

Funders 0

None

BibTeX

@article{Suh_2000, title={Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury}, volume={852}, ISSN={0006-8993}, url={http://dx.doi.org/10.1016/s0006-8993(99)02095-8}, DOI={10.1016/s0006-8993(99)02095-8}, number={2}, journal={Brain Research}, publisher={Elsevier BV}, author={Suh, Sang Won and Chen, Jefferson W. and Motamedi, Massoud and Brent Bell and Listiak, Kathy and Pons, Neus F. and Danscher, Gorm and Frederickson, Christopher J.}, year={2000}, month=jan, pages={268–273} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        12
      ]
    ],
    "date-time": "2025-07-12T01:13:08Z",
    "timestamp": 1752282788424
  },
  "reference-count": 42,
  "publisher": "Elsevier BV",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2000,
            1,
            1
          ]
        ],
        "date-time": "2000-01-01T00:00:00Z",
        "timestamp": 946684800000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2000,
        1
      ]
    ]
  },
  "DOI": "10.1016/s0006-8993(99)02095-8",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T17:48:07Z",
    "timestamp": 1027619287000
  },
  "page": "268-273",
  "source": "Crossref",
  "is-referenced-by-count": 250,
  "title": "Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury",
  "prefix": "10.1016",
  "volume": "852",
  "author": [
    {
      "given": "Sang Won",
      "family": "Suh",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Jefferson W.",
      "family": "Chen",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Massoud",
      "family": "Motamedi",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "family": "Brent Bell",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Kathy",
      "family": "Listiak",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Neus F.",
      "family": "Pons",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Gorm",
      "family": "Danscher",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Christopher J.",
      "family": "Frederickson",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "58",
      "DOI": "10.1016/0006-8993(87)91355-2",
      "article-title": "Selective release of endogenous zinc from the hippocampal mossy fibers in situ",
      "volume": "404",
      "author": "Aniksztejn",
      "year": "1987",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "734",
      "DOI": "10.1038/308734a0",
      "article-title": "Release of endogenous Zn2+ from brain tissue during activity",
      "volume": "308",
      "author": "Assaf",
      "year": "1984",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "861",
      "DOI": "10.1097/00001756-199210000-00010",
      "article-title": "Enrichment of glutamate in zinc-containing terminals of the cat visual cortex",
      "volume": "3",
      "author": "Beaulieu",
      "year": "1992",
      "journal-title": "NeuroReport"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "290",
      "DOI": "10.1111/j.1749-6632.1995.tb16586.x",
      "article-title": "Evidence for prolonged release of excitatory amino acids in severe human head trauma. Relationship to clinical events",
      "volume": "765",
      "author": "Bullock",
      "year": "1995",
      "journal-title": "Ann. N.Y. Acad. Sci."
    },
    {
      "issue": "6",
      "key": "10.1016/S0006-8993(99)02095-8_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "2401",
      "DOI": "10.1046/j.1471-4159.1998.71062401.x",
      "article-title": "Calcium-sensitive fluorescent dyes can report increases in intracellular free zinc concentration in cultured forebrain neurons",
      "volume": "71",
      "author": "Cheng",
      "year": "1998",
      "journal-title": "J. Neurochem."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "347",
      "DOI": "10.1146/annurev.neuro.21.1.347",
      "article-title": "Zinc and brain injury",
      "volume": "21",
      "author": "Choi",
      "year": "1998",
      "journal-title": "Annu. Rev. Neurosci."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "499",
      "DOI": "10.1089/neu.1994.11.499",
      "article-title": "Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models",
      "volume": "11",
      "author": "Clark",
      "year": "1994",
      "journal-title": "J. Neurotraumatol."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "1301",
      "DOI": "10.1097/00001756-199605170-00017",
      "article-title": "Prevention of zinc neurotoxicity in vivo by N,N,N\u2032,N\u2032-tetrakis (2-pyridylmethyl) ethylene-diamine (TPEN)",
      "volume": "7",
      "author": "Cuajungco",
      "year": "1996",
      "journal-title": "NeuroReport"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "1503",
      "DOI": "10.1177/002215549704501107",
      "article-title": "Autometallographic silver enhancement of zinc sulfide crystals created in cryostat sections from human brain biopsies: a new technique that makes it feasible to demonstrate zinc ions in tissue sections from biopsies and early autopsy material",
      "volume": "45",
      "author": "Danscher",
      "year": "1997",
      "journal-title": "J. Histochem. Cytochem."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "363",
      "DOI": "10.1007/BF02331399",
      "article-title": "The autometallographic zinc-sulphide method. A new approach involving in vivo creation of nanometer-sized zinc sulphide crystal lattices in zinc-enriched synaptic and secretory vesicles",
      "volume": "28",
      "author": "Danscher",
      "year": "1996",
      "journal-title": "J. Histochem."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "798",
      "DOI": "10.1126/science.2567056",
      "article-title": "The role of excitatory amino acids and NMDA receptors in traumatic brain injury",
      "volume": "244",
      "author": "Faden",
      "year": "1989",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "317",
      "DOI": "10.1016/0006-8993(89)90199-6",
      "article-title": "Translocation of zinc may contribute to seizure-induced death of neurons",
      "volume": "480",
      "author": "Frederickson",
      "year": "1989",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "91",
      "DOI": "10.1016/0165-0270(87)90042-2",
      "article-title": "A quinoline fluorescence method for visualizing and assaying the histochemically reactive zinc (bouton zinc) in the brain",
      "volume": "20",
      "author": "Frederickson",
      "year": "1987",
      "journal-title": "J. Neurosci. Meth."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "145",
      "DOI": "10.1016/S0074-7742(08)60279-2",
      "article-title": "Neurobiology of zinc and zinc-containing neurons",
      "volume": "31",
      "author": "Frederickson",
      "year": "1989",
      "journal-title": "Int. Rev. Neurobiol."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB15",
      "first-page": "234",
      "article-title": "Temperature dependent release and translocation of zinc in hippocampus in vitro and in vivo",
      "volume": "24",
      "author": "Frederickson",
      "year": "1998",
      "journal-title": "Soc. Neurosci. Abstr."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "736",
      "DOI": "10.1038/308736a0",
      "article-title": "Stimulation-induced uptake and release of zinc in hippocampal slices",
      "volume": "308",
      "author": "Howell",
      "year": "1984",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "327",
      "DOI": "10.1046/j.1460-9568.1999.00437.x",
      "article-title": "Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures",
      "volume": "11",
      "author": "Kim",
      "year": "1999",
      "journal-title": "Eur. J. Neurosci."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "175",
      "DOI": "10.1016/S0306-4522(98)00313-3",
      "article-title": "Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals",
      "volume": "89",
      "author": "Kim",
      "year": "1999",
      "journal-title": "Neuroscience"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "2164",
      "DOI": "10.1523/JNEUROSCI.08-06-02164.1988",
      "article-title": "Zinc alters excitatory amino acid neurotoxicity on cortical neurons",
      "volume": "8",
      "author": "Koh",
      "year": "1988",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "1013",
      "DOI": "10.1126/science.272.5264.1013",
      "article-title": "The role of zinc in selective neuronal death after transient global cerebral ischemia",
      "volume": "272",
      "author": "Koh",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "4846",
      "DOI": "10.1523/JNEUROSCI.12-12-04846.1992",
      "article-title": "Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus",
      "volume": "12",
      "author": "Lowenstein",
      "year": "1992",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "165",
      "DOI": "10.1016/0892-0362(93)90012-D",
      "article-title": "Proconvulsant action of diethyldithiocarbamate in stimulation of the perforant path",
      "volume": "15",
      "author": "Mitchell",
      "year": "1993",
      "journal-title": "Neurotoxicol. Teratol."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "139",
      "DOI": "10.1111/j.1528-1167.1990.tb06298.x",
      "article-title": "Effects of subcutaneous injections of zinc chloride on seizures induced by noise and by kainic acid",
      "volume": "31",
      "author": "Morton",
      "year": "1990",
      "journal-title": "Epilepsia"
    },
    {
      "issue": "2",
      "key": "10.1016/S0006-8993(99)02095-8_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "183",
      "DOI": "10.1038/jcbfm.1993.22",
      "article-title": "Regional changes in interstitial K+ and Ca2+ levels following cortical compression contusion trauma in rats",
      "volume": "13",
      "author": "Nilsson",
      "year": "1993",
      "journal-title": "J. Cereb. Blood Flow Metab."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "14934",
      "DOI": "10.1073/pnas.93.25.14934",
      "article-title": "ZnT-3, a putative transporter of zinc into synaptic vesicles",
      "volume": "93",
      "author": "Palmiter",
      "year": "1996",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "450",
      "DOI": "10.1046/j.1471-4159.1999.0730450.x",
      "article-title": "Induction of an immediate early gene egr-1 by zinc through extracellular signal-regulated kinase activation in cortical culture: its role in zinc-induced neuronal death",
      "volume": "73",
      "author": "Park",
      "year": "1999",
      "journal-title": "J. Neurochem."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB27",
      "unstructured": "D.D. Perrin, Stability Constants of Metal\u2013Ion Complexes: Organic Ligands, Pergamon, Oxford, 1979, pp. 399\u2013405."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "589",
      "DOI": "10.1126/science.2883728",
      "article-title": "Zinc selectively blocks the action of N-methyl-d-aspartate on cortical neurons",
      "volume": "236",
      "author": "Peters",
      "year": "1987",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "9554",
      "DOI": "10.1523/JNEUROSCI.17-24-09554.1997",
      "article-title": "Measurement of intracellular free zinc in living cortical neurons: routes of entry",
      "volume": "17",
      "author": "Sensi",
      "year": "1997",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "2414",
      "DOI": "10.1073/pnas.96.5.2414",
      "article-title": "Preferential Zn2+ influx through Ca2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production",
      "volume": "96",
      "author": "Sensi",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "850",
      "DOI": "10.1126/science.6093256",
      "article-title": "Blockade of N-methyl-d-aspartate receptors may protect against ischemic damage in the brain",
      "volume": "226",
      "author": "Simon",
      "year": "1984",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "150",
      "DOI": "10.1016/0006-8993(85)90017-4",
      "article-title": "A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation",
      "volume": "330",
      "author": "Sloviter",
      "year": "1985",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "265",
      "DOI": "10.1016/S0006-8993(98)00943-3",
      "article-title": "Rapid disappearance of zinc positive terminals in focal brain ischemia",
      "volume": "812",
      "author": "Sorensen",
      "year": "1998",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "91",
      "DOI": "10.1016/0006-8993(76)90577-1",
      "article-title": "Antagonism of cortical excitation of striatal neurons by glutamic acid diethylester: evidence for glutamic acid as an excitatory transmitter in the rat striatum",
      "volume": "102",
      "author": "Spencer",
      "year": "1976",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB35",
      "unstructured": "W. Spielmeyer, Histopathologie des Nerven Systems, Springer, Berlin, 1922, pp. 74\u201379. Original not seen: Cited in: Simon et al., Science, 226 (1984) 850\u2013852."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB36",
      "first-page": "2101",
      "article-title": "Extracellular zinc mediates selective neuronal death in hippocampus and amygdala following kainate-induced seizure",
      "volume": "22",
      "author": "Suh",
      "year": "1996",
      "journal-title": "Soc. Neurosci. Abstr."
    },
    {
      "issue": "7",
      "key": "10.1016/S0006-8993(99)02095-8_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "969",
      "DOI": "10.1177/002215549904700715",
      "article-title": "Detection of pathological zinc accumulation in neurons: methods for autopsy, biopsy and cultured tissue",
      "volume": "47",
      "author": "Suh",
      "year": "1999",
      "journal-title": "J. Histochem. Cytochem."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "123",
      "DOI": "10.1006/abio.1995.1260",
      "article-title": "Lifetime-based fluorescence energy transfer biosensing of zinc",
      "volume": "227",
      "author": "Thompson",
      "year": "1995",
      "journal-title": "Anal. Biochem."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "247",
      "DOI": "10.1016/0304-3940(90)90002-Q",
      "article-title": "Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat",
      "volume": "109",
      "author": "Tonder",
      "year": "1990",
      "journal-title": "Neurosci. Lett."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "640",
      "DOI": "10.1038/328640a0",
      "article-title": "Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons",
      "volume": "328",
      "author": "Westbrook",
      "year": "1987",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "45",
      "DOI": "10.1016/S0006-8993(97)01208-0",
      "article-title": "Kainate-stimulated Zn2+ uptake labels cortical neurons with Ca2+-permeable AMPA/kainate channels",
      "volume": "781",
      "author": "Yin",
      "year": "1998",
      "journal-title": "Brain. Res."
    },
    {
      "key": "10.1016/S0006-8993(99)02095-8_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "2553",
      "DOI": "10.1097/00001756-199512150-00025",
      "article-title": "Zn(2+) permeates Ca(2+) permeable AMPA/kainate channels and triggers selective neural injury",
      "volume": "6",
      "author": "Yin",
      "year": "1995",
      "journal-title": "NeuroReport"
    }
  ],
  "container-title": "Brain Research",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0006899399020958?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0006899399020958?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2020,
        1,
        28
      ]
    ],
    "date-time": "2020-01-28T13:00:04Z",
    "timestamp": 1580216404000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0006899399020958"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2000,
        1
      ]
    ]
  },
  "references-count": 42,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          2000,
          1
        ]
      ]
    }
  },
  "alternative-id": [
    "S0006899399020958"
  ],
  "URL": "http://dx.doi.org/10.1016/S0006-8993(99)02095-8",
  "relation": {},
  "ISSN": [
    "0006-8993"
  ],
  "subject": [],
  "container-title-short": "Brain Research",
  "published": {
    "date-parts": [
      [
        2000,
        1
      ]
    ]
  }
}