DOI: 10.1016/s0006-3223(00)00950-1. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells

Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells

10.1016/s0006-3223(00)00950-1

Crossref journal-article

Elsevier BV

Biological Psychiatry (78)

Bibliography

Rajkowska, G. (2000). Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biological Psychiatry, 48(8), 766â777.

Authors 1

Grazyna Rajkowska (first)

References 97 Referenced 635

10.1001/archpsyc.55.4.362 / Arch Gen Psychiatry / Noise stress impairs prefrontal cortical cognitive function in monkeys by Arnsten (1998)
10.1016/S0006-3223(98)00296-0 / Biol Psychiatry / alpha-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function by Arnsten (1999)
10.1176/ajp.144.7.873 / Am J Psychiatry / CSF corticotropin-releasing factor-like immunoreactivity in depression and schizophrenia by Banki (1987)
10.1176/ajp.157.1.115 / Am J Psychiatry / Hippocampal volume reduction in major depression by Bremner (2000)
10.1016/0306-4522(94)90224-0 / Neuroscience / Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus by Cameron (1994)
10.1016/0006-8993(95)01469-1 / Brain Res / Local infusion of brain-derived neurotrophic factor modifies the firing pattern of dorsal raphe serotonergic neurons by Celada (1996)
Chen G, Rajkowska G, Seraji-Bozorgzad N, Du F, Manji HK (in press): Enhancement of hippocampal neurogenesis by lithium. J Neurochem. (10.1046/j.1471-4159.2000.0751729.x)
10.1046/j.1471-4159.1999.720879.x / J Neurochem / The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS by Chen (1999)
10.1016/0893-133X(89)90028-6 / Neuropsychopharmacology / Evidence for common alterations in cerebral glucose metabolism in major affective disorders and schizophrenia by Cohen (1989)
10.1016/S0920-9964(00)90552-8 / Schizophr Res / Reduced glial density and neuronal volume in major depressive disorder and schizophrenia in the anterior cingulate cortex by Cotter (2000)
10.1038/386824a0 / Nature / Subgenual prefrontal cortex abnormalities in mood disorders by Drevets (1997)
{'key': '10.1016/S0006-3223(00)00950-1_BIB12', 'series-title': 'Neurobiology of Mental Illness', 'first-page': '333', 'article-title': 'The neurochemistry of mood disorders', 'author': 'Duman', 'year': '1999'} / Neurobiology of Mental Illness / The neurochemistry of mood disorders by Duman (1999)
10.1016/0925-4927(96)02744-8 / Psychiatry Res / Increased prefrontal sulcal prominence in relatively young patients with unipolar major depression by Elkis (1996)
10.1111/j.1460-9568.1991.tb00854.x / Eur J Neurosci / Cells that express brain-derived neurotrophic factor mRNA in the developing postnatal brain by Friedman (1991)
10.1159/000212546 / Gerontology / Vasopressin and cardiovascular system in aging by Frolkis (1982)
{'key': '10.1016/S0006-3223(00)00950-1_BIB16', 'series-title': 'The Prefrontal Cortex', 'author': 'Fuster', 'year': '1997'} / The Prefrontal Cortex by Fuster (1997)
10.1126/science.7907431 / Science / Requirement for BDNF in activity-dependent survival of cortical neurons by Ghosh (1994)
10.1126/science.286.5439.548 / Science / Neurogenesis in the neocortex of adult primates by Gould (1999)
10.1016/S0006-3223(99)00247-4 / Biol Psychiatry / Stress and hippocampal neurogenesis by Gould (1999)
10.1002/(SICI)1096-9861(19960729)371:3<362::AID-CNE2>3.0.CO;2-0 / J Comp Neurol / Reactive astrocyte formation in vivo is regulated by noradrenergic axons by Griffith (1996)
10.1111/j.1699-0463.1988.tb00954.x / APMIS / The new stereological tools by Gundersen (1988)
{'key': '10.1016/S0006-3223(00)00950-1_BIB22', 'series-title': 'Psychopharmacology', 'first-page': '535', 'article-title': 'Mechanisms of action of antidepressant treatments', 'author': 'Heninger', 'year': '1987'} / Psychopharmacology / Mechanisms of action of antidepressant treatments by Heninger (1987)
10.1159/000126839 / Neuroendocrinology / Regulatory changes in neuroendocrine stress-integrative circuitry produced by a variable stress paradigm by Herman (1995)
10.1016/S0166-2236(96)10069-2 / Trends Neurosci / Neurocircuitry of stress by Herman (1997)
10.1615/CritRevNeurobiol.v10.i3-4.50 / Crit Rev Neurobiol / Neuronal circuit regulation of the hypothalamo-pituitary-adrenocortical stress axis by Herman (1996)
10.1146/annurev.pa.33.040193.001121 / Annu Rev Pharmacol Toxicol / New antidepressants by Hollister (1993)
10.1016/S0079-6123(08)64586-0 / Prog Brain Res / The role of corticotropin-releasing hormone in the pathogenesis of Cushing’s disease, anorexia nervosa, alcoholism, affective disorders and dementia by Holsboer (1992)
10.1016/0022-510X(85)90141-8 / J Neurol Sci / Activation of vasopressin neurons in the human supraoptic and paraventricular nucleus in senescence and senile dementia by Hoogendijk (1985)
10.1097/00001756-199502000-00015 / Neuroreport / trkC may be an inducible transcription factor target gene by Hughes (1995)
10.1016/0165-3806(92)90103-4 / Brain Res Dev Brain Res / Developmental expression of brain derived neurotrophic factor mRNA by neurons of fetal and adult monkey prefrontal cortex by Huntley (1992)
10.1176/ajp.153.2.151 / Am J Psychiatry / Initiation and adaptation by Hyman (1996)
{'key': '10.1016/S0006-3223(00)00950-1_BIB32', 'series-title': 'Principles of Neural Science', 'first-page': '1041', 'article-title': 'The generation and survival of nerve cells', 'author': 'Jessel', 'year': '2000'} / Principles of Neural Science / The generation and survival of nerve cells by Jessel (2000)
{'key': '10.1016/S0006-3223(00)00950-1_BIB33', 'first-page': '135', 'article-title': 'Etiologic implications of corticosteroid changes in affective disorder', 'volume': '3', 'author': 'Kathol', 'year': '1985', 'journal-title': 'Psychiatr Med'} / Psychiatr Med / Etiologic implications of corticosteroid changes in affective disorder by Kathol (1985)
10.1016/S0006-8993(99)01082-3 / Brain Res / Cellular localization of brain-derived neurotrophic factor-like immunoreactivity in adult monkey brain by Kawamoto (1999)
10.1523/JNEUROSCI.17-21-08451.1997 / J Neurosci / Reduced levels of norepinephrine transporters in the locus coeruleus in major depression by Klimek (1997)
10.1016/0006-8993(94)90387-5 / Brain Res / Postnatal maturation of the layer III pyramidal neurons in the human prefrontal cortex by Koenderink (1994)
10.1016/0304-3940(88)90795-1 / Neurosci Lett / Acetylcholinesterase in the human frontal associative cortex during the period of cognitive development by Kostovic (1988)
10.1176/jnp.3.4.387 / J Neuropsychiatry Clin Neurosci / Hippocampal abnormalities in depression by Krishnan (1991)
10.1093/cercor/9.5.507 / Cereb Cortex / Regionally selective effects of gonadectomy on cortical catecholamine innervation in adult male rats are most disruptive to afferents in prefrontal cortex by Kritzer (1999)
10.1002/(SICI)1096-9861(19990705)409:3<438::AID-CNE8>3.0.CO;2-5 / J Comp Neurol / Ovarian hormones differentially influence immunoreactivity for dopamine beta-hydroxylase, choline acetyltransferase, and serotonin in the dorsolateral prefrontal cortex of adult rhesus monkeys by Kritzer (1999)
10.1016/S0006-3223(99)00266-8 / Biol Psychiatry / Neural circuits mediating stress by Lopez (1999)
10.1016/S0006-3223(97)00484-8 / Biol Psychiatry / A.E. Bennett Research Award. Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus by Lopez (1998)
Lopez JF, Little KY, Watson SJ (2000, May): Corticosteroid receptor regulation in the brain of suicide victims. Abstract presented at the 55th annual convention of the Society of Biological Psychiatry, Chicago. (10.1016/S0006-3223(00)00552-7)
10.1111/j.1365-2826.1994.tb00634.x / J Neuroendocrinol / Activation of vasopressin neurons in aging and Alzheimer’s disease by Lucassen (1994)
10.1016/0896-6273(90)90089-X / Neuron / NT-3, BDNF, and NGF in the developing rat nervous system by Maisonpierre (1990)
10.1523/JNEUROSCI.15-12-07929.1995 / J Neurosci / Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain by Mamounas (1995)
10.1016/S0006-3223(99)00235-8 / Biol Psychiatry / Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain by Manji (1999)
10.1016/S0006-3223(99)00165-1 / Biol Psychiatry / Lithium at 50 by Manji (1999)
Manji HK, Moore GJ, Rajkowska G, Chen G (in press): Neuroplasticity and cellular resilience in mood disorders. Mol Psychiatry. (10.1038/sj.mp.4000811)
10.1016/S0006-8993(97)00297-7 / Brain Res / Serotonin depletion during synaptogenesis leads to decreased synaptic density and learning deficits in the adult rat by Mazer (1997)
{'key': '10.1016/S0006-3223(00)00950-1_BIB51', 'first-page': '1801', 'article-title': 'Stress and hippocampus. An update on current knowledge', 'volume': '20', 'author': 'McEwen', 'year': '1991', 'journal-title': 'Presse Med'} / Presse Med / Stress and hippocampus. An update on current knowledge by McEwen (1991)
10.1038/sj.mp.4000254 / Mol Psychiatry / Possible mechanisms for atrophy of the human hippocampus by McEwen (1997)
10.1176/ajp.156.5.780 / Am J Psychiatry / Prefrontal cortical dysfunction in depression determined by Wisconsin Card Sorting Test performance by Merriam (1999)
Miguel-Hidalgo JJ, Baucom C, Dilley G, et al (in press): GFAP immunoreactivity in the dorsolateral prefrontal cortex separates young from old adults with major depressive disorder. Biol Psychiatry.
10.1016/S0165-0270(99)00114-4 / J Neurosci Methods / Immunohistochemistry of neural markers for the study of the laminar cytoarchitecture in celloidin sections from the human cerebral cortex by Miguel-Hidalgo (1999)
10.1002/(SICI)1096-9861(19980808)395:3<310::AID-CNE4>3.0.CO;2-5 / J Comp Neurol / Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes by Milner (1998)
10.1523/JNEUROSCI.20-04-01568.2000 / J Neurosci / Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction by Mizoguchi (2000)
10.1016/S0006-3223(00)00252-3 / Biol Psychiatry / Lithium increases N-acetyl-aspartate in the human brain by Moore (2000)
Moore GJ, Bebchuk JM, Wilds IB, Chen G, Manji HK (in press): Pharmacologic increase in human gray matter. Lancet.
10.1002/cne.903160408 / J Comp Neurol / Prenatal development of neurons in the human prefrontal cortex. II. A quantitative golgi study by Mrzljak (1992)
10.1016/S0079-6123(08)62681-3 / Prog Brain Res / Neuronal development in human prefrontal cortex in prenatal and postnatal stages by Mrzljak (1990)
10.1016/S0306-4522(98)00219-X / Neuroscience / An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer’s disease by Murer (1999)
10.1016/0960-0760(91)90312-S / J Steroid Biochem / Steroids and depression by Murphy (1991)
10.1523/JNEUROSCI.15-11-07539.1995 / J Neurosci / Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments by Nibuya (1995)
10.1006/exnr.1997.6719 / Exp Neurol / Apoptotic cell death of cultured cerebral cortical neurons induced by withdrawal of astroglial trophic support by Ohgoh (1998)
10.1073/pnas.95.22.13290 / Proc Natl Acad Sci U S A / Glial reduction in the subgenual prefrontal cortex in mood disorders by Ongur (1998)
10.1176/ajp.156.12.1895 / Am J Psychiatry / Low phosphoinositide-specific phospholipase C activity and expression of phospholipase C beta 1 protein in the prefrontal cortex of teenage suicide subjects by Pandey (1999)
10.1001/archpsyc.1996.01830020055007 / Arch Gen Psychiatry / Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression by Purba (1996)
10.1159/000126778 / Neuroendocrinology / Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients by Raadsheer (1994)
10.1176/ajp.152.9.1372 / Am J Psychiatry / Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer’s disease and depression by Raadsheer (1995)
10.1016/S0079-6123(00)26026-3 / Prog Brain Res / Histopathology of the prefrontal cortex in major depression by Rajkowska (2000)
10.1016/S0006-3223(99)00041-4 / Biol Psychiatry / Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression by Rajkowska (1999)
10.1001/archpsyc.55.3.215 / Arch Gen Psychiatry / Neuronal and glial somal size in the prefrontal cortex by Rajkowska (1998)
10.1111/j.1749-6632.1995.tb44717.x / Ann N Y Acad Sci / The neuroendocrinology of menstrual cycle mood disorders by Rubinow (1995)
10.1016/0014-4886(91)90041-A / Exp Neurol / Long-term adrenalectomy causes loss of dentate gyrus and pyramidal neurons in the adult hippocampus by Sapolsky (1991)
10.1523/JNEUROSCI.10-09-02897.1990 / J Neurosci / Hippocampal damage associated with prolonged glucocorticoid exposure in primates by Sapolsky (1990)
10.1523/JNEUROSCI.18-04-01613.1998 / J Neurosci / D1 receptor modulation of hippocampal-prefrontal cortical circuits integrating spatial memory with executive functions in the rat by Seamans (1998)
10.1001/archpsyc.1995.03950220015005 / Arch Gen Psychiatry / Abnormally high neuronal density in the schizophrenic cortex by Selemon (1995)
10.1192/bjp.172.6.527 / Br J Psychiatry / Cortical grey matter reductions associated with treatment-resistant chronic unipolar depression. Controlled magnetic resonance imaging study by Shah (1998)
10.1016/S0006-8993(98)01362-6 / Brain Res / Chronic (−) deprenyl administration alters dendritic morphology of layer III pyramidal neurons in the prefrontal cortex of adult Bonnett monkeys by Shankaranarayana Rao (1999)
10.1073/pnas.93.9.3908 / Proc Natl Acad Sci U S A / Hippocampal atrophy in recurrent major depression by Sheline (1996)
10.1523/JNEUROSCI.19-12-05034.1999 / J Neurosci / Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression by Sheline (1999)
{'key': '10.1016/S0006-3223(00)00950-1_BIB83', 'first-page': '1551', 'article-title': 'Chronic antidepressant exposure enhances 5-hydroxytryptamine7 receptor-mediated cyclic adenosine monophosphate accumulation in rat frontocortical astrocytes', 'volume': '279', 'author': 'Shimizu', 'year': '1996', 'journal-title': 'J Pharmacol Exp Ther'} / J Pharmacol Exp Ther / Chronic antidepressant exposure enhances 5-hydroxytryptamine7 receptor-mediated cyclic adenosine monophosphate accumulation in rat frontocortical astrocytes by Shimizu (1996)
10.1002/(SICI)1097-4547(19980415)52:2<149::AID-JNR3>3.0.CO;2-A / J Neurosci Res / BDNF induction of tryptophan hydroxylase mRNA levels in the rat brain by Siuciak (1998)
10.1016/S0006-3223(99)00170-5 / Biol Psychiatry / Corticotropin-releasing hormone receptor subtypes and emotion by Steckler (1999)
{'key': '10.1016/S0006-3223(00)00950-1_BIB86', 'first-page': '2098', 'article-title': 'Morphometric evaluation of the midbrain dorsal raphe nucleus (DR) in suicide victims with major depression (MD)', 'volume': '25', 'author': 'Stockmeier', 'year': '1999', 'journal-title': 'Abstr Soc Neurosci'} / Abstr Soc Neurosci / Morphometric evaluation of the midbrain dorsal raphe nucleus (DR) in suicide victims with major depression (MD) by Stockmeier (1999)
10.1007/BF00185889 / Anat Embryol (Berl) / Functional neuroanatomy and neuropathology of the human hypothalamus by Swaab (1993)
10.1001/archpsyc.1990.01810230070011 / Arch Gen Psychiatry / Structural brain abnormalities in bipolar affective disorder. Ventricular enlargement and focal signal hyperintensities by Swayze (1990)
10.1016/S0736-5748(98)00029-X / Int J Dev Neurosci / Stress inhibits the proliferation of granule cell precursors in the developing dentate gyrus by Tanapat (1998)
10.1523/JNEUROSCI.16-03-00877.1996 / J Neurosci / Metabolic coupling between glia and neurons by Tsacopoulos (1996)
10.1016/S0006-3223(99)00043-8 / Biol Psychiatry / Morphometry of the dorsal raphe nucleus serotonergic neurons in suicide victims by Underwood (1999)
10.1038/6350 / Nat Neurosci / Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis by Vaccarino (1999)
10.1523/JNEUROSCI.17-08-02785.1997 / J Neurosci / 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex by Vaidya (1997)
10.1002/hipo.450020410 / Hippocampus / Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons by Watanabe (1992)
10.1016/0197-4580(93)90112-O / Neurobiol Aging / New stereological methods for counting neurons by West (1993)
10.1002/syn.890140303 / Synapse / Localization of 5-HT1A receptors to astroglial cells in adult rats by Whitaker-Azmitia (1993)
10.1111/j.1749-6632.1991.tb15637.x / Ann N Y Acad Sci / Receptor activation and its biochemical consequences in astrocytes by Wilkin (1991)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 1:14 p.m.)
Deposited	2 years, 4 months ago (April 10, 2023, 4:45 p.m.)
Indexed	7 hours, 59 minutes ago (Sept. 3, 2025, 6:55 a.m.)
Issued	24 years, 11 months ago (Oct. 1, 2000)
Published	24 years, 11 months ago (Oct. 1, 2000)
Published Print	24 years, 11 months ago (Oct. 1, 2000)

Funders 0

None

BibTeX

@article{Rajkowska_2000, title={Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells}, volume={48}, ISSN={0006-3223}, url={http://dx.doi.org/10.1016/s0006-3223(00)00950-1}, DOI={10.1016/s0006-3223(00)00950-1}, number={8}, journal={Biological Psychiatry}, publisher={Elsevier BV}, author={Rajkowska, Grazyna}, year={2000}, month=oct, pages={766–777} }

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      "first-page": "290",
      "DOI": "10.1159/000212546",
      "article-title": "Vasopressin and cardiovascular system in aging",
      "volume": "28",
      "author": "Frolkis",
      "year": "1982",
      "journal-title": "Gerontology"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB16",
      "series-title": "The Prefrontal Cortex",
      "author": "Fuster",
      "year": "1997"
    },
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      "doi-asserted-by": "crossref",
      "first-page": "1618",
      "DOI": "10.1126/science.7907431",
      "article-title": "Requirement for BDNF in activity-dependent survival of cortical neurons",
      "volume": "263",
      "author": "Ghosh",
      "year": "1994",
      "journal-title": "Science"
    },
    {
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      "DOI": "10.1126/science.286.5439.548",
      "article-title": "Neurogenesis in the neocortex of adult primates",
      "volume": "286",
      "author": "Gould",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "1472",
      "DOI": "10.1016/S0006-3223(99)00247-4",
      "article-title": "Stress and hippocampal neurogenesis",
      "volume": "46",
      "author": "Gould",
      "year": "1999",
      "journal-title": "Biol Psychiatry"
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "362",
      "DOI": "10.1002/(SICI)1096-9861(19960729)371:3<362::AID-CNE2>3.0.CO;2-0",
      "article-title": "Reactive astrocyte formation in vivo is regulated by noradrenergic axons",
      "volume": "371",
      "author": "Griffith",
      "year": "1996",
      "journal-title": "J Comp Neurol"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "857",
      "DOI": "10.1111/j.1699-0463.1988.tb00954.x",
      "article-title": "The new stereological tools",
      "volume": "96",
      "author": "Gundersen",
      "year": "1988",
      "journal-title": "APMIS"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB22",
      "series-title": "Psychopharmacology",
      "first-page": "535",
      "article-title": "Mechanisms of action of antidepressant treatments",
      "author": "Heninger",
      "year": "1987"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "180",
      "DOI": "10.1159/000126839",
      "article-title": "Regulatory changes in neuroendocrine stress-integrative circuitry produced by a variable stress paradigm",
      "volume": "61",
      "author": "Herman",
      "year": "1995",
      "journal-title": "Neuroendocrinology"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "78",
      "DOI": "10.1016/S0166-2236(96)10069-2",
      "article-title": "Neurocircuitry of stress",
      "volume": "20",
      "author": "Herman",
      "year": "1997",
      "journal-title": "Trends Neurosci"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "371",
      "DOI": "10.1615/CritRevNeurobiol.v10.i3-4.50",
      "article-title": "Neuronal circuit regulation of the hypothalamo-pituitary-adrenocortical stress axis",
      "volume": "10",
      "author": "Herman",
      "year": "1996",
      "journal-title": "Crit Rev Neurobiol"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "165",
      "DOI": "10.1146/annurev.pa.33.040193.001121",
      "article-title": "New antidepressants",
      "volume": "33",
      "author": "Hollister",
      "year": "1993",
      "journal-title": "Annu Rev Pharmacol Toxicol"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "385",
      "DOI": "10.1016/S0079-6123(08)64586-0",
      "article-title": "The role of corticotropin-releasing hormone in the pathogenesis of Cushing\u2019s disease, anorexia nervosa, alcoholism, affective disorders and dementia",
      "volume": "93",
      "author": "Holsboer",
      "year": "1992",
      "journal-title": "Prog Brain Res"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "291",
      "DOI": "10.1016/0022-510X(85)90141-8",
      "article-title": "Activation of vasopressin neurons in the human supraoptic and paraventricular nucleus in senescence and senile dementia",
      "volume": "69",
      "author": "Hoogendijk",
      "year": "1985",
      "journal-title": "J Neurol Sci"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "465",
      "DOI": "10.1097/00001756-199502000-00015",
      "article-title": "trkC may be an inducible transcription factor target gene",
      "volume": "6",
      "author": "Hughes",
      "year": "1995",
      "journal-title": "Neuroreport"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "53",
      "DOI": "10.1016/0165-3806(92)90103-4",
      "article-title": "Developmental expression of brain derived neurotrophic factor mRNA by neurons of fetal and adult monkey prefrontal cortex",
      "volume": "70",
      "author": "Huntley",
      "year": "1992",
      "journal-title": "Brain Res Dev Brain Res"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "151",
      "DOI": "10.1176/ajp.153.2.151",
      "article-title": "Initiation and adaptation",
      "volume": "153",
      "author": "Hyman",
      "year": "1996",
      "journal-title": "Am J Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB32",
      "series-title": "Principles of Neural Science",
      "first-page": "1041",
      "article-title": "The generation and survival of nerve cells",
      "author": "Jessel",
      "year": "2000"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB33",
      "first-page": "135",
      "article-title": "Etiologic implications of corticosteroid changes in affective disorder",
      "volume": "3",
      "author": "Kathol",
      "year": "1985",
      "journal-title": "Psychiatr Med"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "341",
      "DOI": "10.1016/S0006-8993(99)01082-3",
      "article-title": "Cellular localization of brain-derived neurotrophic factor-like immunoreactivity in adult monkey brain",
      "volume": "821",
      "author": "Kawamoto",
      "year": "1999",
      "journal-title": "Brain Res"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "8451",
      "DOI": "10.1523/JNEUROSCI.17-21-08451.1997",
      "article-title": "Reduced levels of norepinephrine transporters in the locus coeruleus in major depression",
      "volume": "17",
      "author": "Klimek",
      "year": "1997",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "173",
      "DOI": "10.1016/0006-8993(94)90387-5",
      "article-title": "Postnatal maturation of the layer III pyramidal neurons in the human prefrontal cortex",
      "volume": "653",
      "author": "Koenderink",
      "year": "1994",
      "journal-title": "Brain Res"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "107",
      "DOI": "10.1016/0304-3940(88)90795-1",
      "article-title": "Acetylcholinesterase in the human frontal associative cortex during the period of cognitive development",
      "volume": "90",
      "author": "Kostovic",
      "year": "1988",
      "journal-title": "Neurosci Lett"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "387",
      "DOI": "10.1176/jnp.3.4.387",
      "article-title": "Hippocampal abnormalities in depression",
      "volume": "3",
      "author": "Krishnan",
      "year": "1991",
      "journal-title": "J Neuropsychiatry Clin Neurosci"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "507",
      "DOI": "10.1093/cercor/9.5.507",
      "article-title": "Regionally selective effects of gonadectomy on cortical catecholamine innervation in adult male rats are most disruptive to afferents in prefrontal cortex",
      "volume": "9",
      "author": "Kritzer",
      "year": "1999",
      "journal-title": "Cereb Cortex"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "438",
      "DOI": "10.1002/(SICI)1096-9861(19990705)409:3<438::AID-CNE8>3.0.CO;2-5",
      "article-title": "Ovarian hormones differentially influence immunoreactivity for dopamine beta-hydroxylase, choline acetyltransferase, and serotonin in the dorsolateral prefrontal cortex of adult rhesus monkeys",
      "volume": "409",
      "author": "Kritzer",
      "year": "1999",
      "journal-title": "J Comp Neurol"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "1461",
      "DOI": "10.1016/S0006-3223(99)00266-8",
      "article-title": "Neural circuits mediating stress",
      "volume": "46",
      "author": "Lopez",
      "year": "1999",
      "journal-title": "Biol Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "547",
      "DOI": "10.1016/S0006-3223(97)00484-8",
      "article-title": "A.E. Bennett Research Award. Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus",
      "volume": "43",
      "author": "Lopez",
      "year": "1998",
      "journal-title": "Biol Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB43",
      "doi-asserted-by": "crossref",
      "unstructured": "Lopez JF, Little KY, Watson SJ (2000, May): Corticosteroid receptor regulation in the brain of suicide victims. Abstract presented at the 55th annual convention of the Society of Biological Psychiatry, Chicago.",
      "DOI": "10.1016/S0006-3223(00)00552-7"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "673",
      "DOI": "10.1111/j.1365-2826.1994.tb00634.x",
      "article-title": "Activation of vasopressin neurons in aging and Alzheimer\u2019s disease",
      "volume": "6",
      "author": "Lucassen",
      "year": "1994",
      "journal-title": "J Neuroendocrinol"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "501",
      "DOI": "10.1016/0896-6273(90)90089-X",
      "article-title": "NT-3, BDNF, and NGF in the developing rat nervous system",
      "volume": "5",
      "author": "Maisonpierre",
      "year": "1990",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "7929",
      "DOI": "10.1523/JNEUROSCI.15-12-07929.1995",
      "article-title": "Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain",
      "volume": "15",
      "author": "Mamounas",
      "year": "1995",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "1328",
      "DOI": "10.1016/S0006-3223(99)00235-8",
      "article-title": "Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain",
      "volume": "46",
      "author": "Manji",
      "year": "1999",
      "journal-title": "Biol Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "929",
      "DOI": "10.1016/S0006-3223(99)00165-1",
      "article-title": "Lithium at 50",
      "volume": "46",
      "author": "Manji",
      "year": "1999",
      "journal-title": "Biol Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB49",
      "doi-asserted-by": "crossref",
      "unstructured": "Manji HK, Moore GJ, Rajkowska G, Chen G (in press): Neuroplasticity and cellular resilience in mood disorders. Mol Psychiatry.",
      "DOI": "10.1038/sj.mp.4000811"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "68",
      "DOI": "10.1016/S0006-8993(97)00297-7",
      "article-title": "Serotonin depletion during synaptogenesis leads to decreased synaptic density and learning deficits in the adult rat",
      "volume": "760",
      "author": "Mazer",
      "year": "1997",
      "journal-title": "Brain Res"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB51",
      "first-page": "1801",
      "article-title": "Stress and hippocampus. An update on current knowledge",
      "volume": "20",
      "author": "McEwen",
      "year": "1991",
      "journal-title": "Presse Med"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "255",
      "DOI": "10.1038/sj.mp.4000254",
      "article-title": "Possible mechanisms for atrophy of the human hippocampus",
      "volume": "2",
      "author": "McEwen",
      "year": "1997",
      "journal-title": "Mol Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "780",
      "DOI": "10.1176/ajp.156.5.780",
      "article-title": "Prefrontal cortical dysfunction in depression determined by Wisconsin Card Sorting Test performance",
      "volume": "156",
      "author": "Merriam",
      "year": "1999",
      "journal-title": "Am J Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB54",
      "unstructured": "Miguel-Hidalgo JJ, Baucom C, Dilley G, et al (in press): GFAP immunoreactivity in the dorsolateral prefrontal cortex separates young from old adults with major depressive disorder. Biol Psychiatry."
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "69",
      "DOI": "10.1016/S0165-0270(99)00114-4",
      "article-title": "Immunohistochemistry of neural markers for the study of the laminar cytoarchitecture in celloidin sections from the human cerebral cortex",
      "volume": "93",
      "author": "Miguel-Hidalgo",
      "year": "1999",
      "journal-title": "J Neurosci Methods"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "310",
      "DOI": "10.1002/(SICI)1096-9861(19980808)395:3<310::AID-CNE4>3.0.CO;2-5",
      "article-title": "Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes",
      "volume": "395",
      "author": "Milner",
      "year": "1998",
      "journal-title": "J Comp Neurol"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB57",
      "doi-asserted-by": "crossref",
      "first-page": "1568",
      "DOI": "10.1523/JNEUROSCI.20-04-01568.2000",
      "article-title": "Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction",
      "volume": "20",
      "author": "Mizoguchi",
      "year": "2000",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1016/S0006-3223(00)00252-3",
      "article-title": "Lithium increases N-acetyl-aspartate in the human brain",
      "volume": "48",
      "author": "Moore",
      "year": "2000",
      "journal-title": "Biol Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB59",
      "unstructured": "Moore GJ, Bebchuk JM, Wilds IB, Chen G, Manji HK (in press): Pharmacologic increase in human gray matter. Lancet."
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB60",
      "doi-asserted-by": "crossref",
      "first-page": "485",
      "DOI": "10.1002/cne.903160408",
      "article-title": "Prenatal development of neurons in the human prefrontal cortex. II. A quantitative golgi study",
      "volume": "316",
      "author": "Mrzljak",
      "year": "1992",
      "journal-title": "J Comp Neurol"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB61",
      "doi-asserted-by": "crossref",
      "first-page": "185",
      "DOI": "10.1016/S0079-6123(08)62681-3",
      "article-title": "Neuronal development in human prefrontal cortex in prenatal and postnatal stages",
      "volume": "85",
      "author": "Mrzljak",
      "year": "1990",
      "journal-title": "Prog Brain Res"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB62",
      "doi-asserted-by": "crossref",
      "first-page": "1015",
      "DOI": "10.1016/S0306-4522(98)00219-X",
      "article-title": "An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer\u2019s disease",
      "volume": "88",
      "author": "Murer",
      "year": "1999",
      "journal-title": "Neuroscience"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB63",
      "doi-asserted-by": "crossref",
      "first-page": "537",
      "DOI": "10.1016/0960-0760(91)90312-S",
      "article-title": "Steroids and depression",
      "volume": "38",
      "author": "Murphy",
      "year": "1991",
      "journal-title": "J Steroid Biochem"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB64",
      "doi-asserted-by": "crossref",
      "first-page": "7539",
      "DOI": "10.1523/JNEUROSCI.15-11-07539.1995",
      "article-title": "Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments",
      "volume": "15",
      "author": "Nibuya",
      "year": "1995",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB65",
      "doi-asserted-by": "crossref",
      "first-page": "51",
      "DOI": "10.1006/exnr.1997.6719",
      "article-title": "Apoptotic cell death of cultured cerebral cortical neurons induced by withdrawal of astroglial trophic support",
      "volume": "149",
      "author": "Ohgoh",
      "year": "1998",
      "journal-title": "Exp Neurol"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB66",
      "doi-asserted-by": "crossref",
      "first-page": "13290",
      "DOI": "10.1073/pnas.95.22.13290",
      "article-title": "Glial reduction in the subgenual prefrontal cortex in mood disorders",
      "volume": "95",
      "author": "Ongur",
      "year": "1998",
      "journal-title": "Proc Natl Acad Sci U S A"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB67",
      "doi-asserted-by": "crossref",
      "first-page": "1895",
      "DOI": "10.1176/ajp.156.12.1895",
      "article-title": "Low phosphoinositide-specific phospholipase C activity and expression of phospholipase C beta 1 protein in the prefrontal cortex of teenage suicide subjects",
      "volume": "156",
      "author": "Pandey",
      "year": "1999",
      "journal-title": "Am J Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB68",
      "doi-asserted-by": "crossref",
      "first-page": "137",
      "DOI": "10.1001/archpsyc.1996.01830020055007",
      "article-title": "Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression",
      "volume": "53",
      "author": "Purba",
      "year": "1996",
      "journal-title": "Arch Gen Psychiatry"
    },
    {
      "key": "10.1016/S0006-3223(00)00950-1_BIB69",
      "doi-asserted-by": "crossref",
      "first-page": "436",
      "DOI": "10.1159/000126778",
      "article-title": "Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients",
      "volume": "60",
      "author": "Raadsheer",
      "year": "1994",
      "journal-title": "Neuroendocrinology"
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      "author": "Swayze",
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