DOI: 10.1016/s0006-2952(01)00633-5. Gγ-like (ggl) domains: new frontiers in g-protein signaling and β-propeller scaffolding22Abbreviations: DEP, dishevelled/EGL-10/pleckstrin-related domain; DH, dbl-homology domain; GAP, guanosine triphosphatase-activating protein; GEF, guanine nucleotide exchange factor; GGL, G-gamma-like; GIRK, G-protein-gated inwardly rectifying potassium channel; GPCR, G-protein-coupled receptor; G protein, guanine nucleotide binding protein; GTPase, guanosine triphosphatase; mAChR, muscarinic acetylcholine receptor; MAPK, mitogen-activated protein kinase; PDE, phosphodiesterase; PDZ, PSD-95/Discs-large/ZO-1 related domain; PH, pleckstrin-homology domain; PI3Kγ, gamma isoform of phosphoinositide 3-kinase; PLC-β, beta isoform of phospholipase C; PTB, phosphotyrosine-binding domain; RACK1, receptor for activated C kinase type-1; RBD, Ras-binding domain; RGS, regulators of G-protein signaling; and SAPK, stress-activated protein kinase.

Gγ-like (ggl) domains: new frontiers in g-protein signaling and β-propeller scaffolding22Abbreviations: DEP, dishevelled/EGL-10/pleckstrin-related domain; DH, dbl-homology domain; GAP, guanosine triphosphatase-activating protein; GEF, guanine nucleotide exchange factor; GGL, G-gamma-like; GIRK, G-protein-gated inwardly rectifying potassium channel; GPCR, G-protein-coupled receptor; G protein, guanine nucleotide binding protein; GTPase, guanosine triphosphatase; mAChR, muscarinic acetylcholine receptor; MAPK, mitogen-activated protein kinase; PDE, phosphodiesterase; PDZ, PSD-95/Discs-large/ZO-1 related domain; PH, pleckstrin-homology domain; PI3Kγ, gamma isoform of phosphoinositide 3-kinase; PLC-β, beta isoform of phospholipase C; PTB, phosphotyrosine-binding domain; RACK1, receptor for activated C kinase type-1; RBD, Ras-binding domain; RGS, regulators of G-protein signaling; and SAPK, stress-activated protein kinase.

10.1016/s0006-2952(01)00633-5

Crossref journal-article

Elsevier BV

Biochemical Pharmacology (78)

Bibliography

Sondek, J., & Siderovski, D. P. (2001). GÎ³-like (ggl) domains: new frontiers in g-protein signaling and Î²-propeller scaffolding22Abbreviations: DEP, dishevelled/EGL-10/pleckstrin-related domain; DH, dbl-homology domain; GAP, guanosine triphosphatase-activating protein; GEF, guanine nucleotide exchange factor; GGL, G-gamma-like; GIRK, G-protein-gated inwardly rectifying potassium channel; GPCR, G-protein-coupled receptor; G protein, guanine nucleotide binding protein; GTPase, guanosine triphosphatase; mAChR, muscarinic acetylcholine receptor; MAPK, mitogen-activated protein kinase; PDE, phosphodiesterase; PDZ, PSD-95/Discs-large/ZO-1 related domain; PH, pleckstrin-homology domain; PI3KÎ³, gamma isoform of phosphoinositide 3-kinase; PLC-Î², beta isoform of phospholipase C; PTB, phosphotyrosine-binding domain; RACK1, receptor for activated C kinase type-1; RBD, Ras-binding domain; RGS, regulators of G-protein signaling; and SAPK, stress-activated protein kinase. Biochemical Pharmacology, 61(11), 1329â1337.

Authors 2

John Sondek (first)
David P. Siderovski (additional)

References 85 Referenced 103

10.1146/annurev.bi.56.070187.003151 / Annu Rev Biochem / G proteins by Gilman (1987)
10.1074/jbc.273.2.669 / J Biol Chem / The many faces of G protein signaling by Hamm (1998)
10.1016/S0006-2952(97)00361-4 / Biochem Pharmacol / Rethinking receptor-G protein-effector interactions by Chidiac (1998)
10.1038/ng0692-209 / Nat Genet / A null mutation in the rhodopsin gene causes rod photoreceptor dysfunction and autosomal recessive retinitis pigmentosa by Rosenfeld (1992)
10.1016/S0168-9525(98)01402-4 / Trends Genet / Genetic blindness by Gregory-Evans (1998)
10.1056/NEJM199005173222002 / N Engl J Med / Mutation in the gene encoding the stimulatory G protein of adenylate cyclase in Albright’s hereditary osteodystrophy by Patten (1990)
10.1073/pnas.87.21.8287 / Proc Natl Acad Sci USA / Mutations of the Gs α-subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis by Weinstein (1990)
10.1056/NEJM199112123252403 / N Engl J Med / Activating mutations of the stimulatory G protein in the McCune-Albright syndrome by Weinstein (1991)
10.1073/pnas.89.11.5152 / Proc Natl Acad Sci USA / Identification of a mutation in the gene encoding the α subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome by Schwindinger (1992)
10.1038/292413a0 / Nature / Actions of cholera toxin and the prevention and treatment of cholera by Holmgren (1981)
10.1097/00006454-199704001-00002 / Pediatr Infect Dis J / Pertussis by Hewlett (1997)
10.1126/science.271.5252.1056 / Science / Regulating G protein signaling by Roush (1996)
10.1016/S0165-6147(97)90676-3 / Trends Pharmacol Sci / Orphan G protein-coupled receptors by Stadel (1997)
10.1016/S0092-8674(00)80204-4 / Cell / Structure of RGS4 bound to A1F4−-activated Giα by Tesmer (1997)
10.1038/379311a0 / Nature / The 2.0 Å crystal structure of a heterotrimeric G protein by Lambright (1996)
10.1080/10409239991209273 / Crit Rev Biochem Mol Biol / Whither goest the RGS proteins? by Siderovski (1999)
10.1016/S0955-0674(97)80054-3 / Curr Biol / How receptors talk to trimeric G proteins by Bourne (1997)
10.1038/366654a0 / Nature / The 2.2 Å crystal structure of transducin-α complexed with GTPγ S by Noel (1993)
10.1038/369621a0 / Nature / Structural determinants for activation of the α-subunit of a heterotrimeric G protein by Lambright (1994)
10.1126/science.280.5367.1271 / Science / Molecular basis for interactions of G protein βγ subunits with effectors by Ford (1998)
10.1074/jbc.273.26.16265 / J Biol Chem / Sites for Gα binding on the G protein β subunit overlap with sites for regulation of phospholipase Cβ and adenylyl cyclase by Li (1998)
10.1073/pnas.92.25.11916 / Proc Natl Acad Sci USA / GAIP, a protein that specifically interacts with the trimeric G protein Gαi3, is a member of a protein family with a highly conserved core domain by De Vries (1995)
10.1016/S0960-9822(02)00454-2 / Curr Biol / A new family of regulators of G-protein-coupled receptors? by Siderovski (1996)
10.1128/MCB.16.9.5194 / Mol Cell Biol / Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae by Dohlman (1996)
10.1016/S0092-8674(00)80998-8 / Cell / EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins by Koelle (1996)
10.1006/jmbi.1999.2989 / J Mol Biol / Solution structure of human GAIP (Gα interacting protein) by de Alba (1999)
10.1021/bi992760w / Biochemistry / NMR structure of free RGS4 reveals an induced conformational change upon binding Gα by Moy (2000)
10.1016/S0092-8674(00)80117-8 / Cell / GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein α subunits by Berman (1996)
10.1021/bi9729965 / Biochemistry / Sst2 is a GTPase-activating protein for Gpa1 by Apanovitch (1998)
10.1074/jbc.273.28.17749 / J Biol Chem / GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain by Snow (1998)
10.1089/dna.1994.13.125 / DNA Cell Biol / A human gene encoding a putative basic helix-loop-helix phosphoprotein whose mRNA increases rapidly in cycloheximide-treated blood mononuclear cells by Siderovski (1994)
10.1073/pnas.93.26.15203 / Proc Natl Acad Sci USA / GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of Gαi subunits by De Vries (1996)
10.1038/379742a0 / Nature / Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family by Druey (1996)
10.1016/S0968-0004(99)01474-7 / Trends Biochem Sci / Divergence of RGS proteins by Zheng (1999)
10.1126/science.280.5372.2109 / Science / p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13 by Kozasa (1998)
10.1074/jbc.274.9.5868 / J Biol Chem / A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho by Fukuhara (1999)
10.1126/science.280.5372.2112 / Science / Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Gα13 by Hart (1998)
10.1006/bbrc.1997.6537 / Biochem Biophys Res Commun / Molecular cloning and expression analysis of rat Rgs12 and Rgs14 by Snow (1997)
10.1016/S0968-0004(99)01441-3 / Trends Biochem Sci / The GoLoco motif by Siderovski (1999)
10.1007/s001099900054 / J Mol Med / Raf-like Ras/Rap-binding domains in RGS 12- and still-life-like signalling proteins by Ponting (1999)
10.1042/bj3500019 / Biochem J / RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of Gαo by Traver (2000)
10.1038/35047093 / Nature / Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel by Schiff (2000)
10.1073/pnas.95.22.13307 / Proc Natl Acad Sci USA / A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gβ5 subunits by Snow (1998)
10.1016/S0968-0004(96)30027-3 / Trends Biochem Sci / Pleckstrin’s repeat performance by Ponting (1996)
10.1101/gad.13.14.1780 / Genes Dev / Antagonism between Goα and Gqα in Caenorhabditis elegans by Hajdu-Cronin (1999)
10.1089/dna.1998.17.983 / DNA Cell Biol / dRGS7 encodes a Drosophila homolog of EGL-10 and vertebrate RGS7 by Elmore (1998)
10.1126/science.287.5461.2185 / Science / The genome sequence of Drosophila melanogaster by Adams (2000)
10.1093/nar/28.1.263 / Nucleic Acids Res / The Pfam protein families database by Bateman (2000)
10.1002/bies.950180308 / Bioessays / Kinesin proteins by Moore (1996)
10.1016/S0969-2126(98)00117-8 / Structure / Structural basis of activity and subunit recognition in G protein heterotrimers by Wall (1998)
10.1038/379369a0 / Nature / Crystal structure of a GA-protein βγ dimer at 2.1 Å resolution by Sondek (1996)
10.1074/jbc.274.21.14909 / J Biol Chem / The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform by Yarwood (1999)
10.1126/science.282.5396.2022 / Science / Comparison of the complete protein sets of worm and yeast by Chervitz (1998)
10.1073/pnas.96.11.6489 / Proc Natl Acad Sci USA / Fidelity of G protein β-subunit association by the G protein γ-subunit-like domains of RGS6, RGS7, and RGS11 by Snow (1999)
10.1073/pnas.96.5.2503 / Proc Natl Acad Sci USA / Gβ5 prevents the RGS7-Gαo interaction through binding to a distinct Gγ-like domain found in RGS7 and other RGS proteins by Levay (1999)
10.1074/jbc.274.43.31087 / J Biol Chem / Regulators of G protein signaling 6 and 7. Purification of complexes with Gβ5 and assessment of their effects on G protein-mediated signaling pathways by Posner (1999)
10.1073/pnas.96.5.1947 / Proc Natl Acad Sci USA / The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein β subunit by Makino (1999)
10.1002/(SICI)1097-4547(20000401)60:1<58::AID-JNR6>3.0.CO;2-L / J Neurosci Res / RGS7 complex formation and colocalization with the Gβ5 subunit in the adult rat brain and influence on Gβ5γ2-mediated PLCβ signaling by Liang (2000)
10.1523/JNEUROSCI.20-03-j0004.2000 / J Neurosci (Online) / Copurification of brain G-protein β5 with RGS6 and RGS7 by Zhang (2000)
10.1016/S0021-9258(17)31768-4 / J Biol Chem / A fifth member of the mammalian G-protein β-subunit family. Expression in brain and activation of the β 2 isotype of phospholipase C by Watson (1994)
10.1074/jbc.271.45.28154 / J Biol Chem / A novel form of the G protein β subunit Gβ5 is specifically expressed in the vertebrate retina by Watson (1996)
10.1038/360686a0 / Nature / Subunits βγ of heterotrimeric G protein activate β 2 isoform of phospholipase C by Katz (1992)
10.1096/fasebj.12.11.1019 / FASEB J / Inhibition of adenylyl cyclase isoforms V and VI by various Gβγ subunits by Bayewitch (1998)
10.1074/jbc.273.4.2273 / J Biol Chem / Differential modulation of adenylyl cyclases I and II by various Gβ subunits by Bayewitch (1998)
10.1523/JNEUROSCI.20-06-02183.2000 / J Neurosci / Multiple G-protein βγ combinations produce voltage-dependent inhibition of N-type calcium channels in rat superior cervical ganglion neurons by Ruiz-Velasco (2000)
10.1523/JNEUROSCI.20-19-07143.2000 / J Neurosci / Selective regulation of N-type Ca channels by different combinations of G-protein β/γ subunits and RGS proteins by Zhou (2000)
10.1074/jbc.271.52.33575 / J Biol Chem / Selective activation of effector pathways by brain-specific G protein β5 by Zhang (1996)
10.1074/jbc.275.18.13746 / J Biol Chem / Gβ5γ2 is a highly selective activator of phospholipid-dependent enzymes by Maier (2000)
10.1006/abio.1998.3064 / Anal Biochem / Instability of the G-protein β5 subunit in detergent by Jones (1999)
10.1074/jbc.273.1.636 / J Biol Chem / The G protein β5 subunit interacts selectively with the Gq α subunit by Fletcher (1998)
10.1074/jbc.273.51.34429 / J Biol Chem / Differential activity of the G protein β5/γ2 subunit at receptors and effectors by Lindorfer (1998)
10.1074/jbc.M001535200 / J Biol Chem / Complexes of the G protein subunit Gβ5 with the regulators of G protein signaling RGS7 and RGS9 by Witherow (2000)
10.1038/35000601 / Nature / Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9–1 by Chen (2000)
10.1074/jbc.275.5.3397 / J Biol Chem / Co-expression of Gβ5 enhances the function of two Gγ subunit-like domain-containing regulators of G protein signaling proteins by Kovoor (2000)
10.1146/annurev.pharmtox.37.1.167 / Annu Rev Pharmacol Toxicol / G protein βγ subunits by Clapham (1997)
10.1101/gad.12.16.2610 / Genes Dev / Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways by Axelrod (1998)
10.1074/jbc.M001113200 / J Biol Chem / Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs by de Rooij (2000)
10.1074/jbc.274.53.38260 / J Biol Chem / Palmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10 by Tu (1999)
10.1046/j.1471-4159.2000.0752103.x / J Neurochem / RGS7 is palmitoylated and exists as biochemically distinct forms by Rose (2000)
10.1101/gad.13.14.1763 / Genes Dev / A G-protein signaling network mediated by an RGS protein by Guan (1999)
10.1101/gad.14.16.2003 / Genes Dev / Multiple RGS proteins alter neural G protein signaling to allow C. elegans to rapidly change behavior when fed by Dong (2000)
10.1021/bi9612879 / Biochemistry / Folding of proteins with WD-repeats by Garcia-Higuera (1996)
10.1016/S0969-2126(01)00255-6 / Structure / The three domains of a bacterial sialidase by Gaskell (1995)
10.1006/jmbi.1998.2115 / J Mol Biol / An extracellular β-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components by Springer (1998)
10.1073/pnas.97.3.1096 / Proc Natl Acad Sci USA / Peptide-in-groove interactions link target proteins to the β-propeller of clathrin by ter Haar (2000)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 6:02 p.m.)
Deposited	2 years, 4 months ago (April 13, 2023, 10:39 p.m.)
Indexed	11 months, 2 weeks ago (Sept. 13, 2024, 1:38 p.m.)
Issued	24 years, 3 months ago (June 1, 2001)
Published	24 years, 3 months ago (June 1, 2001)
Published Print	24 years, 3 months ago (June 1, 2001)

Funders 0

None

BibTeX

@article{Sondek_2001, title={Gγ-like (ggl) domains: new frontiers in g-protein signaling and β-propeller scaffolding22Abbreviations: DEP, dishevelled/EGL-10/pleckstrin-related domain; DH, dbl-homology domain; GAP, guanosine triphosphatase-activating protein; GEF, guanine nucleotide exchange factor; GGL, G-gamma-like; GIRK, G-protein-gated inwardly rectifying potassium channel; GPCR, G-protein-coupled receptor; G protein, guanine nucleotide binding protein; GTPase, guanosine triphosphatase; mAChR, muscarinic acetylcholine receptor; MAPK, mitogen-activated protein kinase; PDE, phosphodiesterase; PDZ, PSD-95/Discs-large/ZO-1 related domain; PH, pleckstrin-homology domain; PI3Kγ, gamma isoform of phosphoinositide 3-kinase; PLC-β, beta isoform of phospholipase C; PTB, phosphotyrosine-binding domain; RACK1, receptor for activated C kinase type-1; RBD, Ras-binding domain; RGS, regulators of G-protein signaling; and SAPK, stress-activated protein kinase.}, volume={61}, ISSN={0006-2952}, url={http://dx.doi.org/10.1016/s0006-2952(01)00633-5}, DOI={10.1016/s0006-2952(01)00633-5}, number={11}, journal={Biochemical Pharmacology}, publisher={Elsevier BV}, author={Sondek, John and Siderovski, David P.}, year={2001}, month=jun, pages={1329–1337} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        9,
        13
      ]
    ],
    "date-time": "2024-09-13T17:38:18Z",
    "timestamp": 1726249098516
  },
  "reference-count": 85,
  "publisher": "Elsevier BV",
  "issue": "11",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2001,
            6,
            1
          ]
        ],
        "date-time": "2001-06-01T00:00:00Z",
        "timestamp": 991353600000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2001,
        6
      ]
    ]
  },
  "DOI": "10.1016/s0006-2952(01)00633-5",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T22:02:56Z",
    "timestamp": 1027634576000
  },
  "page": "1329-1337",
  "source": "Crossref",
  "is-referenced-by-count": 103,
  "title": "G\u03b3-like (ggl) domains: new frontiers in g-protein signaling and \u03b2-propeller scaffolding22Abbreviations: DEP, dishevelled/EGL-10/pleckstrin-related domain; DH, dbl-homology domain; GAP, guanosine triphosphatase-activating protein; GEF, guanine nucleotide exchange factor; GGL, G-gamma-like; GIRK, G-protein-gated inwardly rectifying potassium channel; GPCR, G-protein-coupled receptor; G protein, guanine nucleotide binding protein; GTPase, guanosine triphosphatase; mAChR, muscarinic acetylcholine receptor; MAPK, mitogen-activated protein kinase; PDE, phosphodiesterase; PDZ, PSD-95/Discs-large/ZO-1 related domain; PH, pleckstrin-homology domain; PI3K\u03b3, gamma isoform of phosphoinositide 3-kinase; PLC-\u03b2, beta isoform of phospholipase C; PTB, phosphotyrosine-binding domain; RACK1, receptor for activated C kinase type-1; RBD, Ras-binding domain; RGS, regulators of G-protein signaling; and SAPK, stress-activated protein kinase.",
  "prefix": "10.1016",
  "volume": "61",
  "author": [
    {
      "given": "John",
      "family": "Sondek",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "David P.",
      "family": "Siderovski",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "615",
      "DOI": "10.1146/annurev.bi.56.070187.003151",
      "article-title": "G proteins",
      "volume": "56",
      "author": "Gilman",
      "year": "1987",
      "journal-title": "Annu Rev Biochem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "669",
      "DOI": "10.1074/jbc.273.2.669",
      "article-title": "The many faces of G protein signaling",
      "volume": "273",
      "author": "Hamm",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "549",
      "DOI": "10.1016/S0006-2952(97)00361-4",
      "article-title": "Rethinking receptor-G protein-effector interactions",
      "volume": "55",
      "author": "Chidiac",
      "year": "1998",
      "journal-title": "Biochem Pharmacol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "209",
      "DOI": "10.1038/ng0692-209",
      "article-title": "A null mutation in the rhodopsin gene causes rod photoreceptor dysfunction and autosomal recessive retinitis pigmentosa",
      "volume": "1",
      "author": "Rosenfeld",
      "year": "1992",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "103",
      "DOI": "10.1016/S0168-9525(98)01402-4",
      "article-title": "Genetic blindness",
      "volume": "14",
      "author": "Gregory-Evans",
      "year": "1998",
      "journal-title": "Trends Genet"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "1412",
      "DOI": "10.1056/NEJM199005173222002",
      "article-title": "Mutation in the gene encoding the stimulatory G protein of adenylate cyclase in Albright\u2019s hereditary osteodystrophy",
      "volume": "322",
      "author": "Patten",
      "year": "1990",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "8287",
      "DOI": "10.1073/pnas.87.21.8287",
      "article-title": "Mutations of the Gs \u03b1-subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis",
      "volume": "87",
      "author": "Weinstein",
      "year": "1990",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "1688",
      "DOI": "10.1056/NEJM199112123252403",
      "article-title": "Activating mutations of the stimulatory G protein in the McCune-Albright syndrome",
      "volume": "325",
      "author": "Weinstein",
      "year": "1991",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "5152",
      "DOI": "10.1073/pnas.89.11.5152",
      "article-title": "Identification of a mutation in the gene encoding the \u03b1 subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome",
      "volume": "89",
      "author": "Schwindinger",
      "year": "1992",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "413",
      "DOI": "10.1038/292413a0",
      "article-title": "Actions of cholera toxin and the prevention and treatment of cholera",
      "volume": "292",
      "author": "Holmgren",
      "year": "1981",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "S78",
      "DOI": "10.1097/00006454-199704001-00002",
      "article-title": "Pertussis",
      "volume": "16",
      "author": "Hewlett",
      "year": "1997",
      "journal-title": "Pediatr Infect Dis J"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "1056",
      "DOI": "10.1126/science.271.5252.1056",
      "article-title": "Regulating G protein signaling",
      "volume": "271",
      "author": "Roush",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "430",
      "DOI": "10.1016/S0165-6147(97)90676-3",
      "article-title": "Orphan G protein-coupled receptors",
      "volume": "18",
      "author": "Stadel",
      "year": "1997",
      "journal-title": "Trends Pharmacol Sci"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "251",
      "DOI": "10.1016/S0092-8674(00)80204-4",
      "article-title": "Structure of RGS4 bound to A1F4\u2212-activated Gi\u03b1",
      "volume": "89",
      "author": "Tesmer",
      "year": "1997",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "311",
      "DOI": "10.1038/379311a0",
      "article-title": "The 2.0 \u00c5 crystal structure of a heterotrimeric G protein",
      "volume": "379",
      "author": "Lambright",
      "year": "1996",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "215",
      "DOI": "10.1080/10409239991209273",
      "article-title": "Whither goest the RGS proteins?",
      "volume": "34",
      "author": "Siderovski",
      "year": "1999",
      "journal-title": "Crit Rev Biochem Mol Biol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "134",
      "DOI": "10.1016/S0955-0674(97)80054-3",
      "article-title": "How receptors talk to trimeric G proteins",
      "volume": "9",
      "author": "Bourne",
      "year": "1997",
      "journal-title": "Curr Biol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "654",
      "DOI": "10.1038/366654a0",
      "article-title": "The 2.2 \u00c5 crystal structure of transducin-\u03b1 complexed with GTP\u03b3 S",
      "volume": "366",
      "author": "Noel",
      "year": "1993",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "621",
      "DOI": "10.1038/369621a0",
      "article-title": "Structural determinants for activation of the \u03b1-subunit of a heterotrimeric G protein",
      "volume": "369",
      "author": "Lambright",
      "year": "1994",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "1271",
      "DOI": "10.1126/science.280.5367.1271",
      "article-title": "Molecular basis for interactions of G protein \u03b2\u03b3 subunits with effectors",
      "volume": "280",
      "author": "Ford",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "16265",
      "DOI": "10.1074/jbc.273.26.16265",
      "article-title": "Sites for G\u03b1 binding on the G protein \u03b2 subunit overlap with sites for regulation of phospholipase C\u03b2 and adenylyl cyclase",
      "volume": "273",
      "author": "Li",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "11916",
      "DOI": "10.1073/pnas.92.25.11916",
      "article-title": "GAIP, a protein that specifically interacts with the trimeric G protein G\u03b1i3, is a member of a protein family with a highly conserved core domain",
      "volume": "92",
      "author": "De Vries",
      "year": "1995",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "211",
      "DOI": "10.1016/S0960-9822(02)00454-2",
      "article-title": "A new family of regulators of G-protein-coupled receptors?",
      "volume": "6",
      "author": "Siderovski",
      "year": "1996",
      "journal-title": "Curr Biol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "5194",
      "DOI": "10.1128/MCB.16.9.5194",
      "article-title": "Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae",
      "volume": "16",
      "author": "Dohlman",
      "year": "1996",
      "journal-title": "Mol Cell Biol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "115",
      "DOI": "10.1016/S0092-8674(00)80998-8",
      "article-title": "EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins",
      "volume": "84",
      "author": "Koelle",
      "year": "1996",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "927",
      "DOI": "10.1006/jmbi.1999.2989",
      "article-title": "Solution structure of human GAIP (G\u03b1 interacting protein)",
      "volume": "291",
      "author": "de Alba",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "7063",
      "DOI": "10.1021/bi992760w",
      "article-title": "NMR structure of free RGS4 reveals an induced conformational change upon binding G\u03b1",
      "volume": "39",
      "author": "Moy",
      "year": "2000",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "445",
      "DOI": "10.1016/S0092-8674(00)80117-8",
      "article-title": "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein \u03b1 subunits",
      "volume": "86",
      "author": "Berman",
      "year": "1996",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "4815",
      "DOI": "10.1021/bi9729965",
      "article-title": "Sst2 is a GTPase-activating protein for Gpa1",
      "volume": "37",
      "author": "Apanovitch",
      "year": "1998",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "17749",
      "DOI": "10.1074/jbc.273.28.17749",
      "article-title": "GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain",
      "volume": "273",
      "author": "Snow",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "125",
      "DOI": "10.1089/dna.1994.13.125",
      "article-title": "A human gene encoding a putative basic helix-loop-helix phosphoprotein whose mRNA increases rapidly in cycloheximide-treated blood mononuclear cells",
      "volume": "13",
      "author": "Siderovski",
      "year": "1994",
      "journal-title": "DNA Cell Biol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "15203",
      "DOI": "10.1073/pnas.93.26.15203",
      "article-title": "GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G\u03b1i subunits",
      "volume": "93",
      "author": "De Vries",
      "year": "1996",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "742",
      "DOI": "10.1038/379742a0",
      "article-title": "Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family",
      "volume": "379",
      "author": "Druey",
      "year": "1996",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "411",
      "DOI": "10.1016/S0968-0004(99)01474-7",
      "article-title": "Divergence of RGS proteins",
      "volume": "24",
      "author": "Zheng",
      "year": "1999",
      "journal-title": "Trends Biochem Sci"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "2109",
      "DOI": "10.1126/science.280.5372.2109",
      "article-title": "p115 RhoGEF, a GTPase activating protein for G\u03b112 and G\u03b113",
      "volume": "280",
      "author": "Kozasa",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "5868",
      "DOI": "10.1074/jbc.274.9.5868",
      "article-title": "A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho",
      "volume": "274",
      "author": "Fukuhara",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "2112",
      "DOI": "10.1126/science.280.5372.2112",
      "article-title": "Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by G\u03b113",
      "volume": "280",
      "author": "Hart",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "770",
      "DOI": "10.1006/bbrc.1997.6537",
      "article-title": "Molecular cloning and expression analysis of rat Rgs12 and Rgs14",
      "volume": "233",
      "author": "Snow",
      "year": "1997",
      "journal-title": "Biochem Biophys Res Commun"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "340",
      "DOI": "10.1016/S0968-0004(99)01441-3",
      "article-title": "The GoLoco motif",
      "volume": "24",
      "author": "Siderovski",
      "year": "1999",
      "journal-title": "Trends Biochem Sci"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "695",
      "DOI": "10.1007/s001099900054",
      "article-title": "Raf-like Ras/Rap-binding domains in RGS 12- and still-life-like signalling proteins",
      "volume": "77",
      "author": "Ponting",
      "year": "1999",
      "journal-title": "J Mol Med"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "19",
      "DOI": "10.1042/bj3500019",
      "article-title": "RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of G\u03b1o",
      "volume": "350",
      "author": "Traver",
      "year": "2000",
      "journal-title": "Biochem J"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "723",
      "DOI": "10.1038/35047093",
      "article-title": "Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel",
      "volume": "408",
      "author": "Schiff",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "13307",
      "DOI": "10.1073/pnas.95.22.13307",
      "article-title": "A G protein \u03b3 subunit-like domain shared between RGS11 and other RGS proteins specifies binding to G\u03b25 subunits",
      "volume": "95",
      "author": "Snow",
      "year": "1998",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "245",
      "DOI": "10.1016/S0968-0004(96)30027-3",
      "article-title": "Pleckstrin\u2019s repeat performance",
      "volume": "21",
      "author": "Ponting",
      "year": "1996",
      "journal-title": "Trends Biochem Sci"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "1780",
      "DOI": "10.1101/gad.13.14.1780",
      "article-title": "Antagonism between Go\u03b1 and Gq\u03b1 in Caenorhabditis elegans",
      "volume": "13",
      "author": "Hajdu-Cronin",
      "year": "1999",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "983",
      "DOI": "10.1089/dna.1998.17.983",
      "article-title": "dRGS7 encodes a Drosophila homolog of EGL-10 and vertebrate RGS7",
      "volume": "17",
      "author": "Elmore",
      "year": "1998",
      "journal-title": "DNA Cell Biol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "2185",
      "DOI": "10.1126/science.287.5461.2185",
      "article-title": "The genome sequence of Drosophila melanogaster",
      "volume": "287",
      "author": "Adams",
      "year": "2000",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "263",
      "DOI": "10.1093/nar/28.1.263",
      "article-title": "The Pfam protein families database",
      "volume": "28",
      "author": "Bateman",
      "year": "2000",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "207",
      "DOI": "10.1002/bies.950180308",
      "article-title": "Kinesin proteins",
      "volume": "18",
      "author": "Moore",
      "year": "1996",
      "journal-title": "Bioessays"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "1169",
      "DOI": "10.1016/S0969-2126(98)00117-8",
      "article-title": "Structural basis of activity and subunit recognition in G protein heterotrimers",
      "volume": "6",
      "author": "Wall",
      "year": "1998",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "369",
      "DOI": "10.1038/379369a0",
      "article-title": "Crystal structure of a GA-protein \u03b2\u03b3 dimer at 2.1 \u00c5 resolution",
      "volume": "379",
      "author": "Sondek",
      "year": "1996",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "14909",
      "DOI": "10.1074/jbc.274.21.14909",
      "article-title": "The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform",
      "volume": "274",
      "author": "Yarwood",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "2022",
      "DOI": "10.1126/science.282.5396.2022",
      "article-title": "Comparison of the complete protein sets of worm and yeast",
      "volume": "282",
      "author": "Chervitz",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "6489",
      "DOI": "10.1073/pnas.96.11.6489",
      "article-title": "Fidelity of G protein \u03b2-subunit association by the G protein \u03b3-subunit-like domains of RGS6, RGS7, and RGS11",
      "volume": "96",
      "author": "Snow",
      "year": "1999",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "2503",
      "DOI": "10.1073/pnas.96.5.2503",
      "article-title": "G\u03b25 prevents the RGS7-G\u03b1o interaction through binding to a distinct G\u03b3-like domain found in RGS7 and other RGS proteins",
      "volume": "96",
      "author": "Levay",
      "year": "1999",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "31087",
      "DOI": "10.1074/jbc.274.43.31087",
      "article-title": "Regulators of G protein signaling 6 and 7. Purification of complexes with G\u03b25 and assessment of their effects on G protein-mediated signaling pathways",
      "volume": "274",
      "author": "Posner",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB57",
      "doi-asserted-by": "crossref",
      "first-page": "1947",
      "DOI": "10.1073/pnas.96.5.1947",
      "article-title": "The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein \u03b2 subunit",
      "volume": "96",
      "author": "Makino",
      "year": "1999",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "58",
      "DOI": "10.1002/(SICI)1097-4547(20000401)60:1<58::AID-JNR6>3.0.CO;2-L",
      "article-title": "RGS7 complex formation and colocalization with the G\u03b25 subunit in the adult rat brain and influence on G\u03b25\u03b32-mediated PLC\u03b2 signaling",
      "volume": "60",
      "author": "Liang",
      "year": "2000",
      "journal-title": "J Neurosci Res"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB59",
      "doi-asserted-by": "crossref",
      "first-page": "RC59",
      "DOI": "10.1523/JNEUROSCI.20-03-j0004.2000",
      "article-title": "Copurification of brain G-protein \u03b25 with RGS6 and RGS7",
      "volume": "20",
      "author": "Zhang",
      "year": "2000",
      "journal-title": "J Neurosci (Online)"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB60",
      "doi-asserted-by": "crossref",
      "first-page": "22150",
      "DOI": "10.1016/S0021-9258(17)31768-4",
      "article-title": "A fifth member of the mammalian G-protein \u03b2-subunit family. Expression in brain and activation of the \u03b2 2 isotype of phospholipase C",
      "volume": "269",
      "author": "Watson",
      "year": "1994",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB61",
      "doi-asserted-by": "crossref",
      "first-page": "28154",
      "DOI": "10.1074/jbc.271.45.28154",
      "article-title": "A novel form of the G protein \u03b2 subunit G\u03b25 is specifically expressed in the vertebrate retina",
      "volume": "271",
      "author": "Watson",
      "year": "1996",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB62",
      "doi-asserted-by": "crossref",
      "first-page": "686",
      "DOI": "10.1038/360686a0",
      "article-title": "Subunits \u03b2\u03b3 of heterotrimeric G protein activate \u03b2 2 isoform of phospholipase C",
      "volume": "360",
      "author": "Katz",
      "year": "1992",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB63",
      "doi-asserted-by": "crossref",
      "first-page": "1019",
      "DOI": "10.1096/fasebj.12.11.1019",
      "article-title": "Inhibition of adenylyl cyclase isoforms V and VI by various G\u03b2\u03b3 subunits",
      "volume": "12",
      "author": "Bayewitch",
      "year": "1998",
      "journal-title": "FASEB J"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB64",
      "doi-asserted-by": "crossref",
      "first-page": "2273",
      "DOI": "10.1074/jbc.273.4.2273",
      "article-title": "Differential modulation of adenylyl cyclases I and II by various G\u03b2 subunits",
      "volume": "273",
      "author": "Bayewitch",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB65",
      "doi-asserted-by": "crossref",
      "first-page": "2183",
      "DOI": "10.1523/JNEUROSCI.20-06-02183.2000",
      "article-title": "Multiple G-protein \u03b2\u03b3 combinations produce voltage-dependent inhibition of N-type calcium channels in rat superior cervical ganglion neurons",
      "volume": "20",
      "author": "Ruiz-Velasco",
      "year": "2000",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB66",
      "doi-asserted-by": "crossref",
      "first-page": "7143",
      "DOI": "10.1523/JNEUROSCI.20-19-07143.2000",
      "article-title": "Selective regulation of N-type Ca channels by different combinations of G-protein \u03b2/\u03b3 subunits and RGS proteins",
      "volume": "20",
      "author": "Zhou",
      "year": "2000",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB67",
      "doi-asserted-by": "crossref",
      "first-page": "33575",
      "DOI": "10.1074/jbc.271.52.33575",
      "article-title": "Selective activation of effector pathways by brain-specific G protein \u03b25",
      "volume": "271",
      "author": "Zhang",
      "year": "1996",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB68",
      "doi-asserted-by": "crossref",
      "first-page": "13746",
      "DOI": "10.1074/jbc.275.18.13746",
      "article-title": "G\u03b25\u03b32 is a highly selective activator of phospholipid-dependent enzymes",
      "volume": "275",
      "author": "Maier",
      "year": "2000",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB69",
      "doi-asserted-by": "crossref",
      "first-page": "126",
      "DOI": "10.1006/abio.1998.3064",
      "article-title": "Instability of the G-protein \u03b25 subunit in detergent",
      "volume": "268",
      "author": "Jones",
      "year": "1999",
      "journal-title": "Anal Biochem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB70",
      "doi-asserted-by": "crossref",
      "first-page": "636",
      "DOI": "10.1074/jbc.273.1.636",
      "article-title": "The G protein \u03b25 subunit interacts selectively with the Gq \u03b1 subunit",
      "volume": "273",
      "author": "Fletcher",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB71",
      "doi-asserted-by": "crossref",
      "first-page": "34429",
      "DOI": "10.1074/jbc.273.51.34429",
      "article-title": "Differential activity of the G protein \u03b25/\u03b32 subunit at receptors and effectors",
      "volume": "273",
      "author": "Lindorfer",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB72",
      "doi-asserted-by": "crossref",
      "first-page": "24872",
      "DOI": "10.1074/jbc.M001535200",
      "article-title": "Complexes of the G protein subunit G\u03b25 with the regulators of G protein signaling RGS7 and RGS9",
      "volume": "275",
      "author": "Witherow",
      "year": "2000",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB73",
      "doi-asserted-by": "crossref",
      "first-page": "557",
      "DOI": "10.1038/35000601",
      "article-title": "Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9\u20131",
      "volume": "403",
      "author": "Chen",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB74",
      "doi-asserted-by": "crossref",
      "first-page": "3397",
      "DOI": "10.1074/jbc.275.5.3397",
      "article-title": "Co-expression of G\u03b25 enhances the function of two G\u03b3 subunit-like domain-containing regulators of G protein signaling proteins",
      "volume": "275",
      "author": "Kovoor",
      "year": "2000",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB75",
      "doi-asserted-by": "crossref",
      "first-page": "167",
      "DOI": "10.1146/annurev.pharmtox.37.1.167",
      "article-title": "G protein \u03b2\u03b3 subunits",
      "volume": "37",
      "author": "Clapham",
      "year": "1997",
      "journal-title": "Annu Rev Pharmacol Toxicol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB76",
      "doi-asserted-by": "crossref",
      "first-page": "2610",
      "DOI": "10.1101/gad.12.16.2610",
      "article-title": "Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways",
      "volume": "12",
      "author": "Axelrod",
      "year": "1998",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB77",
      "doi-asserted-by": "crossref",
      "first-page": "20829",
      "DOI": "10.1074/jbc.M001113200",
      "article-title": "Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs",
      "volume": "275",
      "author": "de Rooij",
      "year": "2000",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB78",
      "doi-asserted-by": "crossref",
      "first-page": "38260",
      "DOI": "10.1074/jbc.274.53.38260",
      "article-title": "Palmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10",
      "volume": "274",
      "author": "Tu",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB79",
      "doi-asserted-by": "crossref",
      "first-page": "2103",
      "DOI": "10.1046/j.1471-4159.2000.0752103.x",
      "article-title": "RGS7 is palmitoylated and exists as biochemically distinct forms",
      "volume": "75",
      "author": "Rose",
      "year": "2000",
      "journal-title": "J Neurochem"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB80",
      "doi-asserted-by": "crossref",
      "first-page": "1763",
      "DOI": "10.1101/gad.13.14.1763",
      "article-title": "A G-protein signaling network mediated by an RGS protein",
      "volume": "13",
      "author": "Guan",
      "year": "1999",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB81",
      "doi-asserted-by": "crossref",
      "first-page": "2003",
      "DOI": "10.1101/gad.14.16.2003",
      "article-title": "Multiple RGS proteins alter neural G protein signaling to allow C. elegans to rapidly change behavior when fed",
      "volume": "14",
      "author": "Dong",
      "year": "2000",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB82",
      "doi-asserted-by": "crossref",
      "first-page": "13985",
      "DOI": "10.1021/bi9612879",
      "article-title": "Folding of proteins with WD-repeats",
      "volume": "35",
      "author": "Garcia-Higuera",
      "year": "1996",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB83",
      "doi-asserted-by": "crossref",
      "first-page": "1197",
      "DOI": "10.1016/S0969-2126(01)00255-6",
      "article-title": "The three domains of a bacterial sialidase",
      "volume": "3",
      "author": "Gaskell",
      "year": "1995",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB84",
      "doi-asserted-by": "crossref",
      "first-page": "837",
      "DOI": "10.1006/jmbi.1998.2115",
      "article-title": "An extracellular \u03b2-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components",
      "volume": "283",
      "author": "Springer",
      "year": "1998",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0006-2952(01)00633-5_BIB85",
      "doi-asserted-by": "crossref",
      "first-page": "1096",
      "DOI": "10.1073/pnas.97.3.1096",
      "article-title": "Peptide-in-groove interactions link target proteins to the \u03b2-propeller of clathrin",
      "volume": "97",
      "author": "ter Haar",
      "year": "2000",
      "journal-title": "Proc Natl Acad Sci USA"
    }
  ],
  "container-title": "Biochemical Pharmacology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0006295201006335?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0006295201006335?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        4,
        14
      ]
    ],
    "date-time": "2023-04-14T02:39:18Z",
    "timestamp": 1681439958000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0006295201006335"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2001,
        6
      ]
    ]
  },
  "references-count": 85,
  "journal-issue": {
    "issue": "11",
    "published-print": {
      "date-parts": [
        [
          2001,
          6
        ]
      ]
    }
  },
  "alternative-id": [
    "S0006295201006335"
  ],
  "URL": "http://dx.doi.org/10.1016/S0006-2952(01)00633-5",
  "relation": {},
  "ISSN": [
    "0006-2952"
  ],
  "subject": [],
  "container-title-short": "Biochemical Pharmacology",
  "published": {
    "date-parts": [
      [
        2001,
        6
      ]
    ]
  }
}