DOI: 10.1016/s0006-291x(03)00148-7. Unusual function of the activation loop in the protein kinase DYRK1A

Unusual function of the activation loop in the protein kinase DYRK1A

10.1016/s0006-291x(03)00148-7

Crossref journal-article

Elsevier BV

Biochemical and Biophysical Research Communications (78)

Bibliography

Wiechmann, S., Czajkowska, H., de Graaf, K., GrÃ¶tzinger, J., Joost, H.-G., & Becker, W. (2003). Unusual function of the activation loop in the protein kinase DYRK1A. Biochemical and Biophysical Research Communications, 302(2), 403â408.

Authors 6

Stephan Wiechmann (first)
Hanna Czajkowska (additional)
Katrin de Graaf (additional)
Joachim Grötzinger (additional)
Hans-Georg Joost (additional)
Walter Becker (additional)

References 26 Referenced 35

10.1016/S0079-6603(08)60503-6 / Progr. Nucleic Acids Res. Mol. Biol. / Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity by Becker (1999)
10.1101/gad.3.9.1336 / Genes Dev. / Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAK1, whose product may act downstream of the cAMP-dependent protein kinase by Garrett (1989)
10.1101/gad.12.9.1356 / Genes Dev. / Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis by Bähler (1998)
10.1242/dev.125.12.2291 / Development / YakA, a protein kinase required for the transition from growth to development in Dictyostelium by Souza (1998)
10.1074/jbc.271.7.3488 / J. Biol. Chem. / Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII by Kentrup (1996)
10.1074/jbc.273.40.25893 / J. Biol. Chem. / Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases by Becker (1998)
10.1006/bbrc.1998.9967 / Biochem. Biophys. Res. Commun. / Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases by Leder (1999)
10.1093/hmg/5.9.1305 / Hum. Mol. Genet. / A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region by Guimerá (1996)
10.1038/ng0597-28 / Nature Genet. / Functional screening of 2Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome by Smith (1997)
10.1093/hmg/10.18.1915 / Hum. Mol. Genet. / Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down’s syndrome by Altafaj (2001)
10.1096/fasebj.9.8.7768349 / FASEB J. / Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification by Hanks (1995)
10.1042/bj3590497 / Biochem. J. / Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A by Himpel (2001)
10.1074/jbc.M205374200 / J. Biol. Chem. / DYRK3 activation, engagement of protein kinase A/cAMP response element-binding protein, and modulation of progenitor cell survival by Li (2002)
{'key': '10.1016/S0006-291X(03)00148-7_BIB14', 'first-page': '3631', 'article-title': 'Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells', 'volume': '60', 'author': 'Lee', 'year': '2000', 'journal-title': 'Cancer Res.'} / Cancer Res. / Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells by Lee (2000)
10.1093/emboj/20.5.1064 / EMBO J. / Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division by Bähler (2001)
10.1074/jbc.275.4.2431 / J. Biol. Chem. / Specificity determinants of substrate recognition by the protein kinase DYRK1A by Himpel (2000)
10.1074/jbc.271.22.12999 / J. Biol. Chem. / Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation by Gerhartz (1996)
10.1038/84178 / Nat. Struct. Biol. / The structure of Sky1p reveals a novel mechanism for constitutive activity by Nolen (2001)
10.1074/jbc.273.40.25875 / J. Biol. Chem. / Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors by Kim (1998)
10.1016/S0092-8674(00)80351-7 / Cell / Activation mechanism of the MAP kinase ERK2 by dual phosphorylation by Canagarajah (1997)
10.1091/mbc.5.3.297 / Mol. Biol. Cell / A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog by Brill (1994)
10.1128/MCB.18.4.2282 / Mol. Cell. Biol. / Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2α kinases PKR and GCN2 by Romano (1998)
10.1016/S0022-1759(00)00313-6 / J. Immunol. Methods / A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody by Matsuo (2001)
10.1016/S0969-2126(99)80173-7 / Struct. Fold Des. / The structure of phosphorylated p38γ is monomeric and reveals a conserved activation-loop conformation by Bellon (1999)
10.1093/emboj/20.19.5320 / EMBO J. / Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme by Niefind (2001)
10.1074/jbc.274.13.8746 / J. Biol. Chem. / Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity by Brown (1999)

Dates

Type	When
Created	22 years, 5 months ago (Feb. 28, 2003, 9 a.m.)
Deposited	4 years, 2 months ago (June 4, 2021, 6:46 p.m.)
Indexed	11 months, 1 week ago (Sept. 13, 2024, 1:37 p.m.)
Issued	22 years, 5 months ago (March 1, 2003)
Published	22 years, 5 months ago (March 1, 2003)
Published Print	22 years, 5 months ago (March 1, 2003)

Funders 0

None

BibTeX

@article{Wiechmann_2003, title={Unusual function of the activation loop in the protein kinase DYRK1A}, volume={302}, ISSN={0006-291X}, url={http://dx.doi.org/10.1016/s0006-291x(03)00148-7}, DOI={10.1016/s0006-291x(03)00148-7}, number={2}, journal={Biochemical and Biophysical Research Communications}, publisher={Elsevier BV}, author={Wiechmann, Stephan and Czajkowska, Hanna and de Graaf, Katrin and Grötzinger, Joachim and Joost, Hans-Georg and Becker, Walter}, year={2003}, month=mar, pages={403–408} }

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