DOI: 10.1016/s0002-8703(99)70104-3. Long-term oral platelet glycoprotein IIb/IIIa receptor antagonism with sibrafiban after acute coronary syndromes: Study design of the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events post-acute cOroNary sYndromes (SYMPHONY) trial

Long-term oral platelet glycoprotein IIb/IIIa receptor antagonism with sibrafiban after acute coronary syndromes: Study design of the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events post-acute cOroNary sYndromes (SYMPHONY) trial

10.1016/s0002-8703(99)70104-3

Crossref journal-article

Elsevier BV

American Heart Journal (78)

Bibliography

Newby, L. K. (1999). Long-term oral platelet glycoprotein IIb/IIIa receptor antagonism with sibrafiban after acute coronary syndromes: Study design of the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events post-acute cOroNary sYndromes (SYMPHONY) trial. American Heart Journal, 138(2), 210â218.

Authors 1

L.Kristin Newby (first)

References 36 Referenced 34

{'key': '10.1016/S0002-8703(99)70104-3_bib1', 'first-page': '3', 'article-title': '1998 heart and stroke statistical update', 'author': 'American Heart Association', 'year': '1997'} / 1998 heart and stroke statistical update by American Heart Association (1997)
{'key': '10.1016/S0002-8703(99)70104-3_bib2', 'series-title': '1995 summary: national hospital discharge survey', 'author': 'Graves', 'year': '1997'} / 1995 summary: national hospital discharge survey by Graves (1997)
10.1056/NEJM199309023291001 / N Engl J Med / An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction by The GUSTO Investigators (1993)
10.1056/NEJM199609123351103 / N Engl J Med / A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes by The Global Use of Strategies to Open Occluded Coronary Arteries GUSTO IIb Investigators (1996)
10.1161/01.CIR.97.24.2386 / Circulation / International, randomized, controlled trial of lamifiban, a platelet glycoprotein IIb/IIIa inhibitor, heparin, or both in unstable angina by The PARAGON Investigators (1998)
10.1056/NEJM199808133390704 / N Engl J Med / Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes by The PURSUIT Trial Investigators (1998)
10.1056/NEJM199805213382102 / N Engl J Med / Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction by The Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms PRISM-PLUS Study Investigators (1998)
10.1016/S0140-6736(96)09457-3 / Lancet / A randomized, blinded trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE) by CAPRIE Steering Committee (1996)
10.1136/bmj.308.6921.81 / BMJ / Collaborative overview of randomized trials of antiplatelet therapy-I: prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients by Antiplatelet Trialists’ Collaboration (1994)
10.1016/0091-7435(85)90031-3 / Prev Med / A randomized trial of aspirin and β-carotene among US physicians by Hennekens (1985)
Roderick PJ, Wilkes HC, Meade TW. The gastrointestinal toxicity of aspirin: an overview of randomized controlled trials. Br J Clin Pharmacol 193;35:219-26. (10.1111/j.1365-2125.1993.tb05689.x)
10.1016/S0140-6736(67)91658-3 / Lancet / Impaired platelet-connective tissue reaction in man after aspirin ingestion by Weiss (1967)
10.1016/S0140-6736(68)92228-9 / Lancet / Effects of salicylates on human platelets by O’Brien (1968)
10.1016/0049-3848(93)90164-J / Thromb Res / Two-year follow-up of aspirin responder and aspirin non-responder. A pilot trial including 180 post-stroke patients by Grotemeyer (1993)
10.1016/S0735-1097(97)85237-0 / J Am Coll Cardiol / Unexpected, discordant effect of aspirin on platelet reactivity by Farrell (1998)
10.1055/s-0038-1657677 / Thromb Haemost / Variable response to low-dose ASA and the risk of limb deterioration in patients submitted to peripheral arterial angioplasty by Mueller (1997)
{'key': '10.1016/S0002-8703(99)70104-3_bib17', 'first-page': '221', 'article-title': 'Individual variation in the effects of ASA on platelet function: implications for the use of ASA clinically', 'volume': '11', 'author': 'Buchanan', 'year': '1995', 'journal-title': 'Can J Cardiol'} / Can J Cardiol / Individual variation in the effects of ASA on platelet function: implications for the use of ASA clinically by Buchanan (1995)
10.1161/01.CIR.97.1.26 / Circulation / Coronary angioscopic findings in the infarct-related vessel with 1 month of acute myocardial infarction: natural history and the effect of thrombolysis by Van Belle (1998)
10.1161/01.CIR.90.1.61 / Circulation / Persistent activation of coagulation mechanism in unstable angina and myocardial infarction by Merlini (1994)
10.1055/s-0038-1642701 / Thromb Haemost / Platelet integrins by Ginsberg (1995)
10.1056/NEJM199506083322306 / N Engl J Med / Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine by Lefkovits (1995)
10.1161/01.CIR.95.7.1755 / Circulation / Restoration of coronary blood flow in myocardial infarction by intravenous chimeric 7E3 antibody without exogenous plasminogen activators: observations in animals and humans by Gold (1997)
10.1056/NEJM199404073301402 / N Engl J Med / Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty by The EPIC Investigators (1994)
10.1056/NEJM199706123362401 / N Engl J Med / Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization by The EPILOG Investigators (1997)
10.1016/S0140-6736(96)10452-9 / Lancet / Randomized placebo-controlled trial of the abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE study by The CAPTURE Investigators (1997)
10.1016/S0140-6736(98)06113-3 / Lancet / Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade. Evaluation of platelet IIb/IIIa inhibitor for stenting by The EPISTENT Investigators (1998)
10.1056/NEJM199805213382103 / N Engl J Med / A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina by Platelet Receptor Inhibition in Ischemic Syndrome Management PRISM Study Investigators (1998)
10.1016/0735-1097(93)90041-X / J Am Coll Cardiol / Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy. Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI 8) pilot study by Kleiman (1993)
10.1161/01.CIR.95.4.846 / Circulation / Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with integrilin in acute myocardial infarction: results of a randomized, placebo-controlled, dose-ranging trial by Ohman (1997)
{'key': '10.1016/S0002-8703(99)70104-3_bib30', 'first-page': 'I-540', 'article-title': 'Enhanced early reperfusion at 60 minutes with low-dose reteplase combined with full-dose abciximab in acute myocardial infarction: preliminary results from the GUSTO-4 pilot (SPEED) dose-ranging trial', 'volume': '98', 'author': 'Ohman', 'year': '1998', 'journal-title': 'Circulation'} / Circulation / Enhanced early reperfusion at 60 minutes with low-dose reteplase combined with full-dose abciximab in acute myocardial infarction: preliminary results from the GUSTO-4 pilot (SPEED) dose-ranging trial by Ohman (1998)
10.1016/S0735-1097(97)84535-4 / J Am Coll Cardiol / Abciximab (ReoPro) potentiates thrombolysis in ST elevation myocardial infarction: results of TIMI 14 trial by Antman (1998)
10.1097/00005344-199809000-00010 / J Cardiovasc Pharmacol / Pharmacokinetics and pharmacodynamics of sibrafiban (Ro 48-3657), an orally active IIb/IIIa antagonist administered alone or in combination with heparin, aspirin, and recombinant tissue-type plasminogen activator in beagles by Modi (1998)
10.1161/01.CIR.97.4.340 / Circulation / Randomized trial of an oral platelet glyocprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: results of the TIMI 12 trial by Cannon (1998)
10.1161/01.CIR.94.5.899 / Circulation / Platelet membrane glycoprotein IIb/IIIa antagonism in unstable angina. The Canadian Lamifiban Study by Theroux (1996)
10.1016/S0140-6736(96)10172-0 / Lancet / Randomized placebo-controlled trial of eptifibatide on complications of percutaneous coronary intervention: IMPACT II by The IMPACT-II Investigators (1997)
{'key': '10.1016/S0002-8703(99)70104-3_bib36', 'first-page': '800', 'article-title': 'A sharper Bonferroni procedure for multiple tests of significance', 'volume': '74', 'author': 'Hochberg', 'year': '1998', 'journal-title': 'Biometrika'} / Biometrika / A sharper Bonferroni procedure for multiple tests of significance by Hochberg (1998)

Dates

Type	When
Created	19 years, 9 months ago (Nov. 3, 2005, 7:48 a.m.)
Deposited	5 years, 4 months ago (April 10, 2020, 12:45 p.m.)
Indexed	1 year, 1 month ago (July 10, 2024, 1:06 a.m.)
Issued	26 years ago (Aug. 1, 1999)
Published	26 years ago (Aug. 1, 1999)
Published Print	26 years ago (Aug. 1, 1999)

Funders 0

None

BibTeX

@article{Newby_1999, title={Long-term oral platelet glycoprotein IIb/IIIa receptor antagonism with sibrafiban after acute coronary syndromes: Study design of the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events post-acute cOroNary sYndromes (SYMPHONY) trial}, volume={138}, ISSN={0002-8703}, url={http://dx.doi.org/10.1016/s0002-8703(99)70104-3}, DOI={10.1016/s0002-8703(99)70104-3}, number={2}, journal={American Heart Journal}, publisher={Elsevier BV}, author={Newby, L.Kristin}, year={1999}, month=aug, pages={210–218} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        7,
        10
      ]
    ],
    "date-time": "2024-07-10T05:06:12Z",
    "timestamp": 1720587972742
  },
  "reference-count": 36,
  "publisher": "Elsevier BV",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1999,
            8,
            1
          ]
        ],
        "date-time": "1999-08-01T00:00:00Z",
        "timestamp": 933465600000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1999,
        8
      ]
    ]
  },
  "DOI": "10.1016/s0002-8703(99)70104-3",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        11,
        3
      ]
    ],
    "date-time": "2005-11-03T12:48:02Z",
    "timestamp": 1131022082000
  },
  "page": "210-218",
  "source": "Crossref",
  "is-referenced-by-count": 34,
  "title": "Long-term oral platelet glycoprotein IIb/IIIa receptor antagonism with sibrafiban after acute coronary syndromes: Study design of the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events post-acute cOroNary sYndromes (SYMPHONY) trial",
  "prefix": "10.1016",
  "volume": "138",
  "author": [
    {
      "given": "L.Kristin",
      "family": "Newby",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib1",
      "first-page": "3",
      "article-title": "1998 heart and stroke statistical update",
      "author": "American Heart Association",
      "year": "1997"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib2",
      "series-title": "1995 summary: national hospital discharge survey",
      "author": "Graves",
      "year": "1997"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "673",
      "DOI": "10.1056/NEJM199309023291001",
      "article-title": "An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction",
      "volume": "329",
      "author": "The GUSTO Investigators",
      "year": "1993",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "775",
      "DOI": "10.1056/NEJM199609123351103",
      "article-title": "A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes",
      "volume": "335",
      "author": "The Global Use of Strategies to Open Occluded Coronary Arteries GUSTO IIb Investigators",
      "year": "1996",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "2386",
      "DOI": "10.1161/01.CIR.97.24.2386",
      "article-title": "International, randomized, controlled trial of lamifiban, a platelet glycoprotein IIb/IIIa inhibitor, heparin, or both in unstable angina",
      "volume": "97",
      "author": "The PARAGON Investigators",
      "year": "1998",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "436",
      "DOI": "10.1056/NEJM199808133390704",
      "article-title": "Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes",
      "volume": "339",
      "author": "The PURSUIT Trial Investigators",
      "year": "1998",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "1488",
      "DOI": "10.1056/NEJM199805213382102",
      "article-title": "Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction",
      "volume": "338",
      "author": "The Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms PRISM-PLUS Study Investigators",
      "year": "1998",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "1329",
      "DOI": "10.1016/S0140-6736(96)09457-3",
      "article-title": "A randomized, blinded trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)",
      "volume": "348",
      "author": "CAPRIE Steering Committee",
      "year": "1996",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "81",
      "DOI": "10.1136/bmj.308.6921.81",
      "article-title": "Collaborative overview of randomized trials of antiplatelet therapy-I: prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients",
      "volume": "308",
      "author": "Antiplatelet Trialists\u2019 Collaboration",
      "year": "1994",
      "journal-title": "BMJ"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "165",
      "DOI": "10.1016/0091-7435(85)90031-3",
      "article-title": "A randomized trial of aspirin and \u03b2-carotene among US physicians",
      "volume": "14",
      "author": "Hennekens",
      "year": "1985",
      "journal-title": "Prev Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib11",
      "doi-asserted-by": "crossref",
      "unstructured": "Roderick PJ, Wilkes HC, Meade TW. The gastrointestinal toxicity of aspirin: an overview of randomized controlled trials. Br J Clin Pharmacol 193;35:219-26.",
      "DOI": "10.1111/j.1365-2125.1993.tb05689.x"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "495",
      "DOI": "10.1016/S0140-6736(67)91658-3",
      "article-title": "Impaired platelet-connective tissue reaction in man after aspirin ingestion",
      "volume": "2",
      "author": "Weiss",
      "year": "1967",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "779",
      "DOI": "10.1016/S0140-6736(68)92228-9",
      "article-title": "Effects of salicylates on human platelets",
      "volume": "1",
      "author": "O\u2019Brien",
      "year": "1968",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "397",
      "DOI": "10.1016/0049-3848(93)90164-J",
      "article-title": "Two-year follow-up of aspirin responder and aspirin non-responder. A pilot trial including 180 post-stroke patients",
      "volume": "71",
      "author": "Grotemeyer",
      "year": "1993",
      "journal-title": "Thromb Res"
    },
    {
      "issue": "suppl A",
      "key": "10.1016/S0002-8703(99)70104-3_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "352A",
      "DOI": "10.1016/S0735-1097(97)85237-0",
      "article-title": "Unexpected, discordant effect of aspirin on platelet reactivity",
      "volume": "31",
      "author": "Farrell",
      "year": "1998",
      "journal-title": "J Am Coll Cardiol"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "1003",
      "DOI": "10.1055/s-0038-1657677",
      "article-title": "Variable response to low-dose ASA and the risk of limb deterioration in patients submitted to peripheral arterial angioplasty",
      "volume": "78",
      "author": "Mueller",
      "year": "1997",
      "journal-title": "Thromb Haemost"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib17",
      "first-page": "221",
      "article-title": "Individual variation in the effects of ASA on platelet function: implications for the use of ASA clinically",
      "volume": "11",
      "author": "Buchanan",
      "year": "1995",
      "journal-title": "Can J Cardiol"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "26",
      "DOI": "10.1161/01.CIR.97.1.26",
      "article-title": "Coronary angioscopic findings in the infarct-related vessel with 1 month of acute myocardial infarction: natural history and the effect of thrombolysis",
      "volume": "97",
      "author": "Van Belle",
      "year": "1998",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "61",
      "DOI": "10.1161/01.CIR.90.1.61",
      "article-title": "Persistent activation of coagulation mechanism in unstable angina and myocardial infarction",
      "volume": "90",
      "author": "Merlini",
      "year": "1994",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "352",
      "DOI": "10.1055/s-0038-1642701",
      "article-title": "Platelet integrins",
      "volume": "74",
      "author": "Ginsberg",
      "year": "1995",
      "journal-title": "Thromb Haemost"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "1553",
      "DOI": "10.1056/NEJM199506083322306",
      "article-title": "Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine",
      "volume": "332",
      "author": "Lefkovits",
      "year": "1995",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "1755",
      "DOI": "10.1161/01.CIR.95.7.1755",
      "article-title": "Restoration of coronary blood flow in myocardial infarction by intravenous chimeric 7E3 antibody without exogenous plasminogen activators: observations in animals and humans",
      "volume": "95",
      "author": "Gold",
      "year": "1997",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "956",
      "DOI": "10.1056/NEJM199404073301402",
      "article-title": "Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty",
      "volume": "330",
      "author": "The EPIC Investigators",
      "year": "1994",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "1689",
      "DOI": "10.1056/NEJM199706123362401",
      "article-title": "Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization",
      "volume": "336",
      "author": "The EPILOG Investigators",
      "year": "1997",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "1429",
      "DOI": "10.1016/S0140-6736(96)10452-9",
      "article-title": "Randomized placebo-controlled trial of the abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE study",
      "volume": "349",
      "author": "The CAPTURE Investigators",
      "year": "1997",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "87",
      "DOI": "10.1016/S0140-6736(98)06113-3",
      "article-title": "Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade. Evaluation of platelet IIb/IIIa inhibitor for stenting",
      "volume": "352",
      "author": "The EPISTENT Investigators",
      "year": "1998",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "1498",
      "DOI": "10.1056/NEJM199805213382103",
      "article-title": "A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina",
      "volume": "338",
      "author": "Platelet Receptor Inhibition in Ischemic Syndrome Management PRISM Study Investigators",
      "year": "1998",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "381",
      "DOI": "10.1016/0735-1097(93)90041-X",
      "article-title": "Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy. Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI 8) pilot study",
      "volume": "22",
      "author": "Kleiman",
      "year": "1993",
      "journal-title": "J Am Coll Cardiol"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "846",
      "DOI": "10.1161/01.CIR.95.4.846",
      "article-title": "Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with integrilin in acute myocardial infarction: results of a randomized, placebo-controlled, dose-ranging trial",
      "volume": "95",
      "author": "Ohman",
      "year": "1997",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib30",
      "first-page": "I-540",
      "article-title": "Enhanced early reperfusion at 60 minutes with low-dose reteplase combined with full-dose abciximab in acute myocardial infarction: preliminary results from the GUSTO-4 pilot (SPEED) dose-ranging trial",
      "volume": "98",
      "author": "Ohman",
      "year": "1998",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "191A",
      "DOI": "10.1016/S0735-1097(97)84535-4",
      "article-title": "Abciximab (ReoPro) potentiates thrombolysis in ST elevation myocardial infarction: results of TIMI 14 trial",
      "volume": "31",
      "author": "Antman",
      "year": "1998",
      "journal-title": "J Am Coll Cardiol"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "397",
      "DOI": "10.1097/00005344-199809000-00010",
      "article-title": "Pharmacokinetics and pharmacodynamics of sibrafiban (Ro 48-3657), an orally active IIb/IIIa antagonist administered alone or in combination with heparin, aspirin, and recombinant tissue-type plasminogen activator in beagles",
      "volume": "32",
      "author": "Modi",
      "year": "1998",
      "journal-title": "J Cardiovasc Pharmacol"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "340",
      "DOI": "10.1161/01.CIR.97.4.340",
      "article-title": "Randomized trial of an oral platelet glyocprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: results of the TIMI 12 trial",
      "volume": "97",
      "author": "Cannon",
      "year": "1998",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "899",
      "DOI": "10.1161/01.CIR.94.5.899",
      "article-title": "Platelet membrane glycoprotein IIb/IIIa antagonism in unstable angina. The Canadian Lamifiban Study",
      "volume": "94",
      "author": "Theroux",
      "year": "1996",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "1422",
      "DOI": "10.1016/S0140-6736(96)10172-0",
      "article-title": "Randomized placebo-controlled trial of eptifibatide on complications of percutaneous coronary intervention: IMPACT II",
      "volume": "349",
      "author": "The IMPACT-II Investigators",
      "year": "1997",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/S0002-8703(99)70104-3_bib36",
      "first-page": "800",
      "article-title": "A sharper Bonferroni procedure for multiple tests of significance",
      "volume": "74",
      "author": "Hochberg",
      "year": "1998",
      "journal-title": "Biometrika"
    }
  ],
  "container-title": "American Heart Journal",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0002870399701043?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0002870399701043?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2020,
        4,
        10
      ]
    ],
    "date-time": "2020-04-10T16:45:25Z",
    "timestamp": 1586537125000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0002870399701043"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1999,
        8
      ]
    ]
  },
  "references-count": 36,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1999,
          8
        ]
      ]
    }
  },
  "alternative-id": [
    "S0002870399701043"
  ],
  "URL": "http://dx.doi.org/10.1016/S0002-8703(99)70104-3",
  "relation": {},
  "ISSN": [
    "0002-8703"
  ],
  "subject": [],
  "container-title-short": "American Heart Journal",
  "published": {
    "date-parts": [
      [
        1999,
        8
      ]
    ]
  }
}