10.1016/0959-437x(94)90102-3
Crossref journal-article
Elsevier BV
Current Opinion in Genetics & Development (78)
Bibliography

Hinds, P. W., & Weinberg, R. A. (1994). Tumor suppressor genes. Current Opinion in Genetics & Development, 4(1), 135–141.

Authors 2
  1. Philip W. Hinds (first)
  2. Robert A. Weinberg (additional)
References 74 Referenced 161
  1. {'key': '10.1016/0959-437X(94)90102-3_BIB1', 'first-page': '2141', 'article-title': 'Identification of Mutations in the WT1 Gene in Tumours from Patients with the WAGR Syndrome', 'volume': '7', 'author': 'Baird', 'year': '1992', 'journal-title': 'Oncogene'} / Oncogene / Identification of Mutations in the WT1 Gene in Tumours from Patients with the WAGR Syndrome by Baird (1992)
  2. 10.1016/S0021-9258(18)98329-8 / J Biol Chem / The Wilms' Tumor Gene Product WT Activates or Suppresses Transcription Through Separate Functional Domains by Wang (1992)
  3. 10.1016/0168-9525(92)90019-Z / Trends Genet / Wilms' Tumor: Reconciling Genetics and Biology by Van Heyningen (1992)
  4. 10.1038/ng0293-97 / Nature Genet / NF1: A Prevalent Cause of Tumorigenesis in Human Cancers by Seizinger (1993)
  5. 10.1038/ng0293-122 / Nature Genet / Somatic Deletion of the Neurofibromatosis Type-1 Gene in a Neurofibrosarcoma Supports a Tumour Suppressor Gene Hypothesis by Legius (1993)
  6. {'key': '10.1016/0959-437X(94)90102-3_BIB6', 'first-page': '761', 'article-title': 'Analysis of the Neurofibromatosis Type-1 (NF1) GAP-Related Domain by Site-Directed Mutagenesis', 'volume': '8', 'author': 'Gutmann', 'year': '1993', 'journal-title': 'Oncogene'} / Oncogene / Analysis of the Neurofibromatosis Type-1 (NF1) GAP-Related Domain by Site-Directed Mutagenesis by Gutmann (1993)
  7. 10.1016/0092-8674(93)90406-G / Cell / A Novel Moesin, Ezrirr, Radixin-Like Gene is a Candidate for the Neurofibromatosis 2 Tumor Suppressor by Trofatter (1993)
  8. 10.1038/363515a0 / Nature / Alteration in a New Gene Encoding a Putative Membrane-Organizing Protein Causes Neuro-Fibromatosis Type 2 by Rouleau (1993)
  9. 10.1126/science.8493574 / Science / Identification of the con Hippel-Lindau Disease Tumor Suppressor Gene by Latif (1993)
  10. {'key': '10.1016/0959-437X(94)90102-3_BIB10_1', 'first-page': '2846', 'article-title': 'The APC Gene Product in Normal and Tumor Cells', 'volume': '90', 'author': 'Smith', 'year': '1993'} / The APC Gene Product in Normal and Tumor Cells by Smith (1993)
  11. 10.1126/science.1350108 / Science / Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene by Su (1992)
  12. {'key': '10.1016/0959-437X(94)90102-3_BIB12', 'first-page': '95', 'article-title': 'Alteration of the DCC Tumor-Suppressor Gene in Tumorigenic HPV-18 Immortalized Human Keratinocytes Transformed by Nitrosomethylurea', 'volume': '8', 'author': 'Klingelhutz', 'year': '1993', 'journal-title': 'Oncogene'} / Oncogene / Alteration of the DCC Tumor-Suppressor Gene in Tumorigenic HPV-18 Immortalized Human Keratinocytes Transformed by Nitrosomethylurea by Klingelhutz (1993)
  13. {'key': '10.1016/0959-437X(94)90102-3_BIB13', 'first-page': '279', 'article-title': 'Tumor Suppressor Activity of RB and p53 Genes in Human Breast Carcinoma Cells', 'volume': '8', 'author': 'Wang', 'year': '1993', 'journal-title': 'Oncogene'} / Oncogene / Tumor Suppressor Activity of RB and p53 Genes in Human Breast Carcinoma Cells by Wang (1993)
  14. 10.1016/0968-0004(92)90443-D / Trends Biochem Sci / The Retinoblastoma Protein and the Regulation of Cell Cycling by Cobrinik (1992)
  15. 10.1126/science.1329201 / Science / Association of Human Cyclin E with a Periodic G1-S Phase Protein of Kinase by Dulic (1992)
  16. 10.1016/0092-8674(92)90249-C / Cell / Regulation of Retinoblastoma Protein Functions by Ectopic Expression of Human Cyclins by Hinds (1992)
  17. 10.1101/gad.7.5.812 / Genes Dev / Cyclin D1 is a Nuclear Protein Required for Cell Cycle Progression in G1 by Baldin (1993)
  18. 10.1016/0092-8674(93)90136-E / Cell / Functional Interactions of the Retinoblastoma Protein with Mammalian D-Type Cyclins by Ewen (1993)
  19. 10.1016/0092-8674(93)90137-F / Cell / Physical Interaction of the Retinoblastoma Protein with Human D-Cyclins by Dowdy (1993)
  20. 10.1101/gad.7.3.331 / Genes Dev / Direct Binding of Cyclin-D to the Retinoblastoma Gene Product (pRb) and pRb Phosphorylation by the Cyclin D-Dependent Kinase CDK4 by Kato (1993)
  21. Hinds PW, Dowdy SF, Eaton EN, Arnold A, Weinberg RA: Function of a Human Cyclin Gene as an Oncogene. Proc Natl Acad Sci USA in press. (10.1073/pnas.91.2.709)
  22. 10.1126/science.8475385 / Science / Negative Regulation of G1 in Mammalian Cells — Inhibition of Cyclin E Dependent Kinase by TGF-β by Koff (1993)
  23. 10.1016/0092-8674(93)90723-4 / Cell / TGFβ Inhibition of Cdk4 Synthesis is Linked to Cell Cycle Arrest by Ewen (1993)
  24. 10.1038/359288a0 / Nature / Mice Deficient for RB Are Nonvisible and Show Defects in Neurogenesis and Haematopoiesis by Lee (1992)
  25. 10.1038/359295a0 / Nature / Effects of an Rb Mutation in the Mouse by Jacḱs (1992)
  26. 10.1038/359328a0 / Nature / Requirement for a Functional Rb-1 Gene in Murine Development by Clarke (1992)
  27. 10.1002/j.1460-2075.1993.tb05742.x / EMBO J / Interactions of the p107 and Rb Proteins with E2F During the Cell Proliferation Response by Schwarz (1993)
  28. 10.1126/science.1532457 / Science / Interaction of p107 with Cyclin A Independent of Complex Formation with Viral Oncoproteins by Ewen (1992)
  29. 10.1091/mbc.4.4.389 / Mol Cell Biol / Transcriptional Repression by the Rb-Related Protein p107 by Zamanian (1993)
  30. 10.1126/science.1411535 / Science / E2F—A Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins by Nevins (1992)
  31. 10.1128/MCB.13.7.3975 / Mol Cell Biol / Cell Cycle Analysis of E2F in Primary Human T Cells Reveals Novel E2F Complexes and Biochemically Distinct Forms of Free E2E by Chittenden (1993)
  32. 10.1038/358259a0 / Nature / Retinoblastoma Protein Switches the E2F Site from a Positive to a Negative Element by Weintraub (1992)
  33. 10.1128/JVI.67.4.2402-2407.1993 / J Virol / The Human Papillomavirus E7 Oncoprotein and the Cellular Transcription Factor E2F Bind to Separate Sites on the Retinoblastoma Tumor Suppressor Protein by Wu (1993)
  34. 10.1093/nar/20.22.5947 / Nucleic Acids Res / Retinoblastoma-Repression of E2F-Dependent Transcription Depends on the Ability of the Retinoblastoma Protein to Interact with E2F and is Abrogated by the Adenovirus E1A Oncoprotein by Arroyo (1992)
  35. 10.1128/MCB.13.2.953 / Mol Cell Biol / Protein Domains Governing Interactions Between E2F, the Retinoblastoma Gene Product, and Human Papillomvirus Type-16 E7 Protein by Huang (1993)
  36. 10.1038/365349a0 / Nature / Expression of Transcription Factor E2F1 Induces Quiescent Cells to Enter S Phase by Johnson (1993)
  37. 10.1016/0092-8674(93)90497-E / Cell / A C-Terminal Protein-Binding Domain in the Retinoblastoma Protein Regulates Nuclear c-abl Tyrosine Kinase in the Cell Cycle by Welch (1993)
  38. 10.1038/356215a0 / Nature / Mice Deficient for p53 are Developmentally Normal but Susceptible to Spontaneous Tumors by Donehower (1992)
  39. {'key': '10.1016/0959-437X(94)90102-3_BIB39', 'first-page': '6304', 'article-title': 'Participation of p53 in the Cellular Response to DNA Damage', 'volume': '51', 'author': 'Kastan', 'year': '1991', 'journal-title': 'Cancer Res'} / Cancer Res / Participation of p53 in the Cellular Response to DNA Damage by Kastan (1991)
  40. {'key': '10.1016/0959-437X(94)90102-3_BIB40', 'first-page': '7491', 'article-title': 'Wild-Type p53 is a Cell Cycle Checkpoint Determinant Following Irradiation', 'volume': '89', 'author': 'Kuerbitz', 'year': '1992'} / Wild-Type p53 is a Cell Cycle Checkpoint Determinant Following Irradiation by Kuerbitz (1992)
  41. 10.1016/0092-8674(92)90593-2 / Cell / A Mammalian Cell Cycle Checkpoint Pathway Utilizing p53 and GADD45 is Defective in Ataxia-Telangiectasia by Kastan (1992)
  42. 10.1038/365022a0 / Nature / Cell Checkpoint and Radiosensitivity by Murnane (1993)
  43. 10.1016/0092-8674(92)90244-7 / Cell / Wild-Type p53 Restores Cell Cycle Control and Inhibits Gene Amplifications in Cells with Mutant p53 Alleles by Yin (1992)
  44. 10.1016/0092-8674(92)90243-6 / Cell / Altered Cell Cycle Arrest and Gene Amplification Potential Accompany Loss of Wild-Type p53 by Livingstone (1992)
  45. 10.1016/B978-0-12-364932-4.50010-1 / Int Rev Exp Pathol / Apoptosis: Mechanisms and Roles in Pathology by Arends (1991)
  46. 10.1038/352345a0 / Nature / Wild-Type p53 Induces Apoptosis of Myeloid Leukemic Cells that is inhibited by Interleukin-6 by Yonish-Rouach (1991)
  47. 10.1101/gad.7.4.546 / Genes Dev / Wild-Type p53 Mediates Apoptosis by E1A, which is Inhibited by E1B by Debbas (1993)
  48. 10.1101/gad.7.4.535 / Genes Dev / Stabilization of the p53 Tumor Suppressor is Induced by Adenovirus 5 E1A and Accompanies Apoptosis by Lowe (1993)
  49. 10.1038/362847a0 / Nature / p53 is Required for Radiation-Induced Apoptosis in Mouse Thymocytes by Lowe (1993)
  50. 10.1038/362849a0 / Nature / Thymocyte Apoptosis Induced by p53-Dependent and Independent Pathways by Clarke (1993)
  51. {'key': '10.1016/0959-437X(94)90102-3_BIB51', 'first-page': '307', 'article-title': 'Induction of Nuclear Accumulation of the Tumor-Suppressor Protein p53 by DNA-Damaging Agents', 'volume': '8', 'author': 'Fritsche', 'year': '1993', 'journal-title': 'Oncogene'} / Oncogene / Induction of Nuclear Accumulation of the Tumor-Suppressor Protein p53 by DNA-Damaging Agents by Fritsche (1993)
  52. 10.1016/0092-8674(93)90719-7 / Cell / p53-Dependent Apoptosis Modulates the Cytotoxicity of Anticancer Agents by Lowe (1993)
  53. 10.1038/bjc.1993.40 / Br J Cancer / Apoptosis by Wyllie (1993)
  54. 10.1038/ng0492-45 / Nature Genet / Definition of a Consensus Binding Site for p53 by El-Deiry (1992)
  55. 10.1101/gad.6.7.1143 / Genes Dev / Wild-Type p53 Mediates Positive Regulation of Gene Expression Through a Specific DNA Sequence Element by Zambetti (1992)
  56. 10.1128/MCB.12.6.2866 / Mol Cell Biol / A Transcriptionally Active DNA-Binding Site for Human p53 by Funk (1992)
  57. 10.1126/science.1589764 / Science / Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression by Kern (1992)
  58. 10.1128/MCB.12.12.5581 / Mol Cell Biol / Identification of a Minimal Transforming Domain of p53: Negative Dominance Through Abrogation of Sequence-Specific DNA Binding by Shaulian (1992)
  59. 10.1038/357082a0 / Nature / Inhibition of p53 Transactivation Required for Transformation by Adenovirus Early 1B Protein by Yew (1992)
  60. 10.1002/j.1460-2075.1992.tb05608.x / EMBO J / The Transcriptional Transactivation Function of Wild-Type p53 is Inhibited by SV40 Large T-Antigen and by HPV-16 E6 Oncoprotein by Mietz (1992)
  61. 10.1038/358083a0 / Nature / Wild-Type p53 Activates Transcription in Vitro by Farmer (1992)
  62. 10.1016/0092-8674(92)90644-R / Cell / The mdm-2 Oncogene Product Forms a Complex with the p53 Protein and Inhibits p53-Mediated Transactivation by Momand (1992)
  63. 10.1038/362857a0 / Nature / Oncoprotein MDM2 Conceals the Activation Domain of Tumour Suppressor p53 by Oliner (1993)
  64. 10.1016/S0021-9258(18)53769-8 / J Biol Chem / Direct Interaction Between the Transcriptional Activation Domain of Human p53 and the TATA Box-Binding Protein by Truant (1993)
  65. 10.1016/S0021-9258(19)38619-3 / J Biol Chem / p53 Binds to the TATA-Binding Protein-TATA Complex by Martin (1993)
  66. 10.1128/MCB.13.6.3291 / Mol Cell Biol / The p53 Activation Domain Binds TATA Box-Binding Polypeptide in Holo-TFIID, and a Neighboring p53 Domain Inhibits Transcription by Liu (1993)
  67. {'key': '10.1016/0959-437X(94)90102-3_BIB67_1', 'first-page': '12028', 'article-title': 'Wild-Type p53 Binds to the TATA-Binding Protein and Represses Transcription', 'volume': '89', 'author': 'Seto', 'year': '1992'} / Wild-Type p53 Binds to the TATA-Binding Protein and Represses Transcription by Seto (1992)
  68. {'key': '10.1016/0959-437X(94)90102-3_BIB68', 'first-page': '1183', 'article-title': 'Wild-Type but not Mutant p53 Can Repress Transcription Initiation in Vitro by Interfering with the Binding of Basal Transcription Factors to the TATA Motif', 'volume': '8', 'author': 'Ragimov', 'year': '1993', 'journal-title': 'Oncogene'} / Oncogene / Wild-Type but not Mutant p53 Can Repress Transcription Initiation in Vitro by Interfering with the Binding of Basal Transcription Factors to the TATA Motif by Ragimov (1993)
  69. 10.1038/363281a0 / Nature / Specific Repression of TATA-Mediated but not Initiator-Mediated Transcription by Wild-Type p53 by Mack (1993)
  70. 10.1016/0092-8674(93)90649-B / Cell / The Acidic Transcriptional Activation Domains of VP16 and p53 Bind the Cellular Replication Protein A and Stimulate in Vitro BPV-1 DNA Replication by Li (1993)
  71. 10.1016/0092-8674(93)90650-F / Cell / The transactivator Proteins VP16 and GAL4 Bind Replication Factor A by He (1993)
  72. 10.1038/365079a0 / Nature / Inhibition of DNA Replication Factor RPA by p53 by Dutta (1993)
  73. 10.1016/0092-8674(93)90500-P / Cell / WAF1, a Potential Mediator of p53 Tumor Suppression by El-Deiry (1993)
  74. 10.1016/0092-8674(93)90499-G / Cell / The p21 Cdk-Interacting Protein Cip1 is a Potent Inhibitor of G1 Cyclin-Dependent Kinases by Harper (1993)
Dates
Type When
Created 21 years, 2 months ago (May 26, 2004, 6:25 p.m.)
Deposited 4 years, 2 months ago (June 17, 2021, 8:33 p.m.)
Indexed 1 month, 4 weeks ago (June 25, 2025, 10:29 a.m.)
Issued 31 years, 6 months ago (Feb. 1, 1994)
Published 31 years, 6 months ago (Feb. 1, 1994)
Published Print 31 years, 6 months ago (Feb. 1, 1994)
Funders 0

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@article{Hinds_1994, title={Tumor suppressor genes}, volume={4}, ISSN={0959-437X}, url={http://dx.doi.org/10.1016/0959-437x(94)90102-3}, DOI={10.1016/0959-437x(94)90102-3}, number={1}, journal={Current Opinion in Genetics & Development}, publisher={Elsevier BV}, author={Hinds, Philip W. and Weinberg, Robert A.}, year={1994}, month=feb, pages={135–141} }