DOI: 10.1016/0169-328x(92)90202-m. Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1

Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1

10.1016/0169-328x(92)90202-m

Crossref journal-article

Elsevier BV

Molecular Brain Research (78)

Bibliography

Forloni, G., Demicheli, F., Giorgi, S., Bendotti, C., & Angeretti, N. (1992). Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1. Molecular Brain Research, 16(1â2), 128â134.

Authors 5

Gianluigi Forloni (first)
Federica Demicheli (additional)
Sussana Giorgi (additional)
Caterina Bendotti (additional)
Nadia Angeretti (additional)

References 62 Referenced 194

10.1016/0006-8993(92)90380-R / Brain Res. / β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease by Araujo (1992)
10.1016/0306-4522(91)90412-H / Neuroscience / Receptors for interleukin-1 (α and β) in mouse brain: mapping and neuronal localization in hippocampus by Ban (1991)
10.1126/science.3299701 / Science / Localization of amyloid β protein messenger RNA in brains from patients with Alzheimer's disease by Bahmanyer (1987)
{'key': '10.1016/0169-328X(92)90202-M_BIB4', 'first-page': '204', 'article-title': 'Evidence that vascular endothelial cells can induce tha retraction of fibrin clots', 'volume': '168', 'author': 'Barbieri', 'year': '1981'} / Evidence that vascular endothelial cells can induce tha retraction of fibrin clots by Barbieri (1981)
{'key': '10.1016/0169-328X(92)90202-M_BIB5', 'first-page': '3628', 'article-title': 'Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid and lesioned mice', 'volume': '85', 'author': 'Bendotti', 'year': '1988'} / Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid and lesioned mice by Bendotti (1988)
10.1523/JNEUROSCI.11-03-00600.1991 / J. Neurosci. / Distribution of GAP-43 mRNA in the brain stem of adult rats as evidenced by in situ hybridization: localization within monoaminergic neurons by Bendotti (1991)
10.1002/jnr.490250321 / J. Neurosci. Res. / The Alzheimer's amyloid precursor protein is produced by type I astrocytes in primary cultures of rat neuroglia by Berkenbosch (1990)
10.4049/jimmunol.147.7.2122 / J. Immunol. / Murine endothelioma cell lines transformed by polyoma middle T oncogene as target for and producers of cytokines by Bussolino (1991)
10.1016/0896-6273(88)90131-6 / Neuron / Immunocytochemical localization of the precursor protein for β-amyloid in the rat central nervous system by Card (1987)
10.1111/j.1471-4159.1991.tb08197.x / J. Neurochem. / Regulation by interleukin 1 of nerve growth factor secretion and nerve growth factor mRNA expression in rat primary astroglial cultures by Carman-Krzan (1991)
{'key': '10.1016/0169-328X(92)90202-M_BIB11', 'first-page': '156', 'article-title': 'Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction', 'volume': '162', 'author': 'Chomczynsky', 'year': '1987', 'journal-title': 'Anal. Biochem.'} / Anal. Biochem. / Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction by Chomczynsky (1987)
10.1016/0304-3940(91)90318-N / Neurosci. Lett. / Abnormal production of interleukin-1 by microglia from trisomy 16 mice by Colton (1991)
10.1089/dna.1988.7.261 / DNA / p1B15: cDNA clone of the rat mRNA encoding cyclophilin by Danielson (1988)
10.1126/science.2569763 / Science / A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein by De Sauvage (1989)
10.1007/BF00712843 / Cell Mol. Neurobiol. / Interleukin-1 stimulates the beta-amyloid precursor protein promoter by Donnelly (1990)
{'key': '10.1016/0169-328X(92)90202-M_BIB16', 'first-page': '8362', 'article-title': 'Effects of injected Alzheimer β-amyloid cores in rat brain', 'volume': '88', 'author': 'Frautschy', 'year': '1991'} / Effects of injected Alzheimer β-amyloid cores in rat brain by Frautschy (1991)
10.1016/0304-3940(90)90687-5 / Neurosci. Lett. / Interleukin-1 β and tumor necrosis factor-α synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes by Gadient (1990)
10.1126/science.3872478 / Science / Interleukin-1 stimulation of astroglial proliferation after brain injury by Giulian (1985)
10.1084/jem.164.2.594 / J. Exp. Med. / Interleukin-1 of the central nervous system is produced by ameboid microglia by Giulian (1986)
10.1016/S0006-291X(84)80190-4 / Biochem. Biophys. Res. Commun. / Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein by Glenner (1984)
10.1038/349704a0 / Nature / Segregation of missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease by Goate (1991)
{'key': '10.1016/0169-328X(92)90202-M_BIB22', 'first-page': '760', 'article-title': 'Interleukin-1 regulates synthesis of amyloid β-protein precursor mRNA in human endothelial cells', 'volume': '86', 'author': 'Goldgaber', 'year': '1989'} / Interleukin-1 regulates synthesis of amyloid β-protein precursor mRNA in human endothelial cells by Goldgaber (1989)
{'key': '10.1016/0169-328X(92)90202-M_BIB23', 'first-page': '7611', 'article-title': "Brain Interleukin-1 and S-100 immunoreactivity are elevated in Down Syndrome and Alzheimer's disease", 'volume': '86', 'author': 'Griffin', 'year': '1989'} / Brain Interleukin-1 and S-100 immunoreactivity are elevated in Down Syndrome and Alzheimer's disease by Griffin (1989)
10.1007/BF00687883 / Acta Neuropathol. / Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain by Haag (1989)
{'key': '10.1016/0169-328X(92)90202-M_BIB25', 'series-title': 'Interspecies divergence of 3′ non coding regions', 'first-page': '673', 'article-title': 'Complementary DNA sequence of a human cytoplasmatic actin', 'volume': '163', 'author': 'Hanokoglu', 'year': '1983'} / Interspecies divergence of 3′ non coding regions / Complementary DNA sequence of a human cytoplasmatic actin by Hanokoglu (1983)
10.1111/j.1471-4159.1991.tb08160.x / J. Neurochem. / Proteolytic cleavage of the Alzheimer's disease amyloid A4 precursor protein by Ishiura (1991)
10.1016/0197-4580(91)90090-7 / Neurobiol. Aging / Quantitative measurement of alternatively spliced amyloid precursor protein mRNA expression in Alzheimer's disease and normal brain by S1 nuclease protection analysis by Jacobsen (1991)
10.1126/science.2111579 / Science / Relation of neuronal APP 751/APP 695 and neurite plaque density in Alzheimer's disease by Johnson (1990)
10.1038/325733a0 / Nature / The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor by Kang (1987)
10.1016/0006-291X(90)90992-V / Biochem. Biophys. Res. Commun. / Differential splicing of Alzheimer's disease amyloid A4 precursor RNA in rat tissues: pre A4 695 mRNA is predominantly produced in rat and human brain by Kang (1990)
10.1016/S0006-291X(88)80805-2 / Biochem. Biophysic. Res. Commun. / Identification of a high-affinity receptor for interleukin-1 beta in rat brain by Katsuura (1988)
10.1038/331530a0 / Nature / Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity by Kitaguchi (1988)
10.1016/0014-5793(90)81181-M / FEBS lett. / Retinoic acid induced differentiated neuroblastoma cells show increased expression of the βA4 amyloid gene of Alzheimer's disease and an altered splicing pattern by Konig (1990)
10.1016/0169-328X(91)90010-U / Molec. Brain Res. / Alternative splicing of the βA4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's diseases patients by Konig (1991)
{'key': '10.1016/0169-328X(92)90202-M_BIB35', 'first-page': '7247', 'article-title': 'An in vivo model for the neurodegenerative effects of β-amyloid and protection by substance P', 'volume': '88', 'author': 'Kowall', 'year': '1991'} / An in vivo model for the neurodegenerative effects of β-amyloid and protection by substance P by Kowall (1991)
{'key': '10.1016/0169-328X(92)90202-M_BIB36', 'first-page': '573.7', 'article-title': 'APP gene expression in specific cell types of the rat CNS', 'volume': '21', 'author': 'Le Blanc', 'year': '1991', 'journal-title': 'Soc.. Neurosci. Abstr.'} / Soc.. Neurosci. Abstr. / APP gene expression in specific cell types of the rat CNS by Le Blanc (1991)
{'key': '10.1016/0169-328X(92)90202-M_BIB37', 'first-page': '1691', 'article-title': 'Distribution of precursor amyloid-β-protein messenger RNA in human cerebral cortex: relationship to neurofibrillary tangles and neurite plaques', 'volume': '86', 'author': 'Lewis', 'year': '1988'} / Distribution of precursor amyloid-β-protein messenger RNA in human cerebral cortex: relationship to neurofibrillary tangles and neurite plaques by Lewis (1988)
{'key': '10.1016/0169-328X(92)90202-M_BIB38', 'first-page': '2743', 'article-title': 'Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments', 'volume': '81', 'author': 'Lewis', 'year': '1984'} / Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments by Lewis (1984)
10.1212/WNL.40.4.635 / Neurology / Astrocytes and the plaques of Alzheimer's disease by Mandybur (1990)
{'year': '1980', 'author': 'Maniatis', 'key': '10.1016/0169-328X(92)90202-M_BIB40'} by Maniatis (1980)
10.1093/ije/20.Supplement_2.S28 / Int. J. Epidemiol. / Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies by Mortimer (1991)
10.1016/0140-6736(91)91612-X / Lancet / Mis-sense mutation Val-to-ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease by Narute (1991)
10.1016/0169-328X(87)90012-X / Mol. Brain Res. / The neuronal growth associated protein GAP-43 (B-50, F1): neuronal specificity, developmental regulation and regional distribution of the huma and rat mRNAs by Neve (1987)
10.1016/0896-6273(88)90166-3 / Neuron / Expression of the Alzheimer's amyloid precursor gene transcripts in the human brain by Neve (1988)
10.1016/0896-6273(90)90169-G / Neuron / The Alzheimer's amyloid precursor-related transcript lacking the β/A4 sequence is specifically increased in Alzheimer's disease brain by Neve (1990)
10.1038/331525a0 / Nature / A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors by Ponte (1988)
{'key': '10.1016/0169-328X(92)90202-M_BIB47', 'first-page': '4190', 'article-title': 'Molecular cloning ane charcaterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptide', 'volume': '84', 'author': 'Robakis', 'year': '1987'} / Molecular cloning ane charcaterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptide by Robakis (1987)
10.1016/0140-6736(91)92724-G / Lancet / βA4 amyloid protein deposition in brain after head trauma by Roberts (1991)
10.1016/0896-6273(91)90052-2 / Neuron / The molecular pathology of Alzheimer's disease by Selkoe (1991)
10.1016/0896-6273(89)90252-3 / Neuron / Expression of β-amyloid precursor protein in reactive astrocytes following neuronal damage by Siman (1989)
10.1016/0169-328X(91)90095-F / Mol. Brain Res. / Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of β-amyloid precursor mRNAs in the PC 12 cell line by Smith (1991)
10.1210/endo-127-6-3070 / Endocrinology / Interleukin-1 receptors in mouse brain: characterization and neuronal localization by Takao (1990)
10.1016/S0006-291X(88)80273-0 / Biochem. Biophys. Res. Commun. / Three types of amyloid protein precursor mRNA in human brain: their differential expression in Alzheimer's disease by Tanaka (1988)
{'key': '10.1016/0169-328X(92)90202-M_BIB54', 'first-page': '77', 'article-title': 'Amyloid β protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus', 'volume': '237', 'author': 'Tanzi', 'year': '1987', 'journal-title': 'Science'} / Science / Amyloid β protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus by Tanzi (1987)
10.1038/331528a0 / Nature / Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease by Tanzi (1988)
{'key': '10.1016/0169-328X(92)90202-M_BIB56', 'first-page': '353', 'article-title': "Failure of familial Alzheimer's disease to segregate with the A4-amyloid gene in several European families", 'volume': '329', 'author': 'Van Broeckoven', 'year': '1987', 'journal-title': 'Nature'} / Nature / Failure of familial Alzheimer's disease to segregate with the A4-amyloid gene in several European families by Van Broeckoven (1987)
10.1016/0169-328X(88)90004-6 / Mol. Brain Res. / Absence of mutation in the β-amyloid cDNAs cloned from the brains of three patients with sporadic Alzheimer's disease by Vitek (1988)
10.1016/0092-8674(88)90536-3 / Cell / Embryonic lethalities and endothelial tumors in chimeric mice expressing polyoma virus middle T oncogene by Williams (1988)
10.1016/0092-8674(89)90343-7 / Cell / Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment by Williams (1989)
10.1007/BF00688170 / Acta Neuropathol. / Spectrum of morphological appearance of amyloid deposits in Alzheimer's by Wisniewski (1989)
{'key': '10.1016/0169-328X(92)90202-M_BIB61', 'first-page': '120', 'article-title': 'Subpial β/A4 amyloid deposition occurs between astroglial processes in Alzheimer-type dementia', 'volume': '223', 'author': 'Yamaguchi', 'year': '1991', 'journal-title': 'Neurosci. Lett.'} / Neurosci. Lett. / Subpial β/A4 amyloid deposition occurs between astroglial processes in Alzheimer-type dementia by Yamaguchi (1991)
10.1126/science.2218531 / Science / Neurotrophic neuropoxic effects of amyloid β protein: reversal by tachynin neuropeptides by Yankner (1990)

Dates

Type	When
Created	22 years, 4 months ago (April 24, 2003, 11:25 p.m.)
Deposited	1 year, 7 months ago (Jan. 9, 2024, 2:45 p.m.)
Indexed	2 months ago (July 6, 2025, 1:26 p.m.)
Issued	32 years, 10 months ago (Nov. 1, 1992)
Published	32 years, 10 months ago (Nov. 1, 1992)
Published Print	32 years, 10 months ago (Nov. 1, 1992)

Funders 0

None

BibTeX

@article{Forloni_1992, title={Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1}, volume={16}, ISSN={0169-328X}, url={http://dx.doi.org/10.1016/0169-328x(92)90202-m}, DOI={10.1016/0169-328x(92)90202-m}, number={1–2}, journal={Molecular Brain Research}, publisher={Elsevier BV}, author={Forloni, Gianluigi and Demicheli, Federica and Giorgi, Sussana and Bendotti, Caterina and Angeretti, Nadia}, year={1992}, month=nov, pages={128–134} }

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      "article-title": "Receptors for interleukin-1 (\u03b1 and \u03b2) in mouse brain: mapping and neuronal localization in hippocampus",
      "volume": "43",
      "author": "Ban",
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      "author": "Barbieri",
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      "first-page": "3628",
      "article-title": "Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid and lesioned mice",
      "volume": "85",
      "author": "Bendotti",
      "year": "1988"
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      "volume": "11",
      "author": "Bendotti",
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      "year": "1990",
      "journal-title": "J. Neurosci. Res."
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      "author": "Donnelly",
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    },
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      "key": "10.1016/0169-328X(92)90202-M_BIB16",
      "first-page": "8362",
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      "volume": "117",
      "author": "Gadient",
      "year": "1990",
      "journal-title": "Neurosci. Lett."
    },
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      "author": "Giulian",
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      "DOI": "10.1016/S0006-291X(84)80190-4",
      "article-title": "Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein",
      "volume": "120",
      "author": "Glenner",
      "year": "1984",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "704",
      "DOI": "10.1038/349704a0",
      "article-title": "Segregation of missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease",
      "volume": "349",
      "author": "Goate",
      "year": "1991",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB22",
      "first-page": "760",
      "article-title": "Interleukin-1 regulates synthesis of amyloid \u03b2-protein precursor mRNA in human endothelial cells",
      "volume": "86",
      "author": "Goldgaber",
      "year": "1989"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB23",
      "first-page": "7611",
      "article-title": "Brain Interleukin-1 and S-100 immunoreactivity are elevated in Down Syndrome and Alzheimer's disease",
      "volume": "86",
      "author": "Griffin",
      "year": "1989"
    },
    {
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      "first-page": "569",
      "DOI": "10.1007/BF00687883",
      "article-title": "Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain",
      "volume": "77",
      "author": "Haag",
      "year": "1989",
      "journal-title": "Acta Neuropathol."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB25",
      "series-title": "Interspecies divergence of 3\u2032 non coding regions",
      "first-page": "673",
      "article-title": "Complementary DNA sequence of a human cytoplasmatic actin",
      "volume": "163",
      "author": "Hanokoglu",
      "year": "1983"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "363",
      "DOI": "10.1111/j.1471-4159.1991.tb08160.x",
      "article-title": "Proteolytic cleavage of the Alzheimer's disease amyloid A4 precursor protein",
      "volume": "56",
      "author": "Ishiura",
      "year": "1991",
      "journal-title": "J. Neurochem."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "585",
      "DOI": "10.1016/0197-4580(91)90090-7",
      "article-title": "Quantitative measurement of alternatively spliced amyloid precursor protein mRNA expression in Alzheimer's disease and normal brain by S1 nuclease protection analysis",
      "volume": "12",
      "author": "Jacobsen",
      "year": "1991",
      "journal-title": "Neurobiol. Aging"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "854",
      "DOI": "10.1126/science.2111579",
      "article-title": "Relation of neuronal APP 751/APP 695 and neurite plaque density in Alzheimer's disease",
      "volume": "248",
      "author": "Johnson",
      "year": "1990",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "733",
      "DOI": "10.1038/325733a0",
      "article-title": "The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor",
      "volume": "325",
      "author": "Kang",
      "year": "1987",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "1192",
      "DOI": "10.1016/0006-291X(90)90992-V",
      "article-title": "Differential splicing of Alzheimer's disease amyloid A4 precursor RNA in rat tissues: pre A4 695 mRNA is predominantly produced in rat and human brain",
      "volume": "166",
      "author": "Kang",
      "year": "1990",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "61",
      "DOI": "10.1016/S0006-291X(88)80805-2",
      "article-title": "Identification of a high-affinity receptor for interleukin-1 beta in rat brain",
      "volume": "156",
      "author": "Katsuura",
      "year": "1988",
      "journal-title": "Biochem. Biophysic. Res. Commun."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "350",
      "DOI": "10.1038/331530a0",
      "article-title": "Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity",
      "volume": "331",
      "author": "Kitaguchi",
      "year": "1988",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "305",
      "DOI": "10.1016/0014-5793(90)81181-M",
      "article-title": "Retinoic acid induced differentiated neuroblastoma cells show increased expression of the \u03b2A4 amyloid gene of Alzheimer's disease and an altered splicing pattern",
      "volume": "269",
      "author": "Konig",
      "year": "1990",
      "journal-title": "FEBS lett."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "259",
      "DOI": "10.1016/0169-328X(91)90010-U",
      "article-title": "Alternative splicing of the \u03b2A4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's diseases patients",
      "volume": "9",
      "author": "Konig",
      "year": "1991",
      "journal-title": "Molec. Brain Res."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB35",
      "first-page": "7247",
      "article-title": "An in vivo model for the neurodegenerative effects of \u03b2-amyloid and protection by substance P",
      "volume": "88",
      "author": "Kowall",
      "year": "1991"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB36",
      "first-page": "573.7",
      "article-title": "APP gene expression in specific cell types of the rat CNS",
      "volume": "21",
      "author": "Le Blanc",
      "year": "1991",
      "journal-title": "Soc.. Neurosci. Abstr."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB37",
      "first-page": "1691",
      "article-title": "Distribution of precursor amyloid-\u03b2-protein messenger RNA in human cerebral cortex: relationship to neurofibrillary tangles and neurite plaques",
      "volume": "86",
      "author": "Lewis",
      "year": "1988"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB38",
      "first-page": "2743",
      "article-title": "Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments",
      "volume": "81",
      "author": "Lewis",
      "year": "1984"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "635",
      "DOI": "10.1212/WNL.40.4.635",
      "article-title": "Astrocytes and the plaques of Alzheimer's disease",
      "volume": "40",
      "author": "Mandybur",
      "year": "1990",
      "journal-title": "Neurology"
    },
    {
      "year": "1980",
      "author": "Maniatis",
      "key": "10.1016/0169-328X(92)90202-M_BIB40"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "S28",
      "DOI": "10.1093/ije/20.Supplement_2.S28",
      "article-title": "Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies",
      "volume": "20",
      "author": "Mortimer",
      "year": "1991",
      "journal-title": "Int. J. Epidemiol."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "978",
      "DOI": "10.1016/0140-6736(91)91612-X",
      "article-title": "Mis-sense mutation Val-to-ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease",
      "volume": "337",
      "author": "Narute",
      "year": "1991",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "177",
      "DOI": "10.1016/0169-328X(87)90012-X",
      "article-title": "The neuronal growth associated protein GAP-43 (B-50, F1): neuronal specificity, developmental regulation and regional distribution of the huma and rat mRNAs",
      "volume": "2",
      "author": "Neve",
      "year": "1987",
      "journal-title": "Mol. Brain Res."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "669",
      "DOI": "10.1016/0896-6273(88)90166-3",
      "article-title": "Expression of the Alzheimer's amyloid precursor gene transcripts in the human brain",
      "volume": "1",
      "author": "Neve",
      "year": "1988",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "329",
      "DOI": "10.1016/0896-6273(90)90169-G",
      "article-title": "The Alzheimer's amyloid precursor-related transcript lacking the \u03b2/A4 sequence is specifically increased in Alzheimer's disease brain",
      "volume": "5",
      "author": "Neve",
      "year": "1990",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "1080",
      "DOI": "10.1038/331525a0",
      "article-title": "A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors",
      "volume": "331",
      "author": "Ponte",
      "year": "1988",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB47",
      "first-page": "4190",
      "article-title": "Molecular cloning ane charcaterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptide",
      "volume": "84",
      "author": "Robakis",
      "year": "1987"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "1422",
      "DOI": "10.1016/0140-6736(91)92724-G",
      "article-title": "\u03b2A4 amyloid protein deposition in brain after head trauma",
      "volume": "338",
      "author": "Roberts",
      "year": "1991",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "487",
      "DOI": "10.1016/0896-6273(91)90052-2",
      "article-title": "The molecular pathology of Alzheimer's disease",
      "volume": "6",
      "author": "Selkoe",
      "year": "1991",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "275",
      "DOI": "10.1016/0896-6273(89)90252-3",
      "article-title": "Expression of \u03b2-amyloid precursor protein in reactive astrocytes following neuronal damage",
      "volume": "3",
      "author": "Siman",
      "year": "1989",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "351",
      "DOI": "10.1016/0169-328X(91)90095-F",
      "article-title": "Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of \u03b2-amyloid precursor mRNAs in the PC 12 cell line",
      "volume": "10",
      "author": "Smith",
      "year": "1991",
      "journal-title": "Mol. Brain Res."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "3070",
      "DOI": "10.1210/endo-127-6-3070",
      "article-title": "Interleukin-1 receptors in mouse brain: characterization and neuronal localization",
      "volume": "127",
      "author": "Takao",
      "year": "1990",
      "journal-title": "Endocrinology"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "472",
      "DOI": "10.1016/S0006-291X(88)80273-0",
      "article-title": "Three types of amyloid protein precursor mRNA in human brain: their differential expression in Alzheimer's disease",
      "volume": "157",
      "author": "Tanaka",
      "year": "1988",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB54",
      "first-page": "77",
      "article-title": "Amyloid \u03b2 protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus",
      "volume": "237",
      "author": "Tanzi",
      "year": "1987",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "528",
      "DOI": "10.1038/331528a0",
      "article-title": "Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease",
      "volume": "331",
      "author": "Tanzi",
      "year": "1988",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB56",
      "first-page": "353",
      "article-title": "Failure of familial Alzheimer's disease to segregate with the A4-amyloid gene in several European families",
      "volume": "329",
      "author": "Van Broeckoven",
      "year": "1987",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB57",
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      "first-page": "121",
      "DOI": "10.1016/0169-328X(88)90004-6",
      "article-title": "Absence of mutation in the \u03b2-amyloid cDNAs cloned from the brains of three patients with sporadic Alzheimer's disease",
      "volume": "4",
      "author": "Vitek",
      "year": "1988",
      "journal-title": "Mol. Brain Res."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "121",
      "DOI": "10.1016/0092-8674(88)90536-3",
      "article-title": "Embryonic lethalities and endothelial tumors in chimeric mice expressing polyoma virus middle T oncogene",
      "volume": "52",
      "author": "Williams",
      "year": "1988",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB59",
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      "DOI": "10.1016/0092-8674(89)90343-7",
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      "volume": "57",
      "author": "Williams",
      "year": "1989",
      "journal-title": "Cell"
    },
    {
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      "first-page": "337",
      "DOI": "10.1007/BF00688170",
      "article-title": "Spectrum of morphological appearance of amyloid deposits in Alzheimer's",
      "volume": "78",
      "author": "Wisniewski",
      "year": "1989",
      "journal-title": "Acta Neuropathol."
    },
    {
      "key": "10.1016/0169-328X(92)90202-M_BIB61",
      "first-page": "120",
      "article-title": "Subpial \u03b2/A4 amyloid deposition occurs between astroglial processes in Alzheimer-type dementia",
      "volume": "223",
      "author": "Yamaguchi",
      "year": "1991",
      "journal-title": "Neurosci. Lett."
    },
    {
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      "first-page": "279",
      "DOI": "10.1126/science.2218531",
      "article-title": "Neurotrophic neuropoxic effects of amyloid \u03b2 protein: reversal by tachynin neuropeptides",
      "volume": "250",
      "author": "Yankner",
      "year": "1990",
      "journal-title": "Science"
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