DOI: 10.1016/0166-4328(93)90134-c. Environmental influences on the central nervous system and their implications for the aging rat

Environmental influences on the central nervous system and their implications for the aging rat

10.1016/0166-4328(93)90134-c

Crossref journal-article

Elsevier BV

Behavioural Brain Research (78)

Bibliography

Mohammed, A. H., Henriksson, B. G., SÃ¶derstrÃ¶m, S., Ebendal, T., Olsson, T., & Seckl, J. R. (1993). Environmental influences on the central nervous system and their implications for the aging rat. Behavioural Brain Research, 57(2), 183â191.

Authors 6

Abdul H. Mohammed (first)
Bengt G. Henriksson (additional)
Stine Söderström (additional)
Ted Ebendal (additional)
Tommy Olsson (additional)
Jonathan R. Seckl (additional)

References 102 Referenced 158

10.1016/0031-9384(69)90179-6 / Physiol. Behav. / Effects of early experience on adrenocortical reactivity by Ader (1969)
Alridge, J. and Seckl, J.R., Quantitation of emulsion autoradiography in situ hybridization using image analysis and rate of change filters, J. Anat., in press.
{'key': '10.1016/0166-4328(93)90134-C_BIB3', 'series-title': 'Physiology and Cell Biology of Aging', 'first-page': '141', 'article-title': 'Brain plasticity, memory and aging', 'author': 'Bennett', 'year': '1979'} / Physiology and Cell Biology of Aging / Brain plasticity, memory and aging by Bennett (1979)
10.1126/science.146.3644.610 / Science / Chemical and anatomical plasticity of brain by Bennett (1964)
10.1126/science.163.3869.825 / Science / Rat brain: effects of environmental enrichment on wet and dry weights by Bennett (1969)
{'key': '10.1016/0166-4328(93)90134-C_BIB6', 'series-title': 'Molecular Approaches to Learning', 'first-page': '55', 'article-title': 'Time course of effects of differential experience on brain measures and behavior of rats', 'author': 'Bennett', 'year': '1970'} / Molecular Approaches to Learning / Time course of effects of differential experience on brain measures and behavior of rats by Bennett (1970)
10.1037/h0062513 / J. Comp. Physiol. Psychol. / The effect of different environments during infancy on adult behavior in the rat by Bingham (1952)
10.1002/dev.420220707 / Dev. Psychobiol. / Effects of complex experience on somatic growth and organ development in rats by Black (1989)
10.1016/0197-4580(91)90009-9 / Neurobiol. Aging / Usual vs. successful aging: some notes on experiential factors by Black (1991)
10.1523/JNEUROSCI.13-06-02582.1993 / J. Neurosci. / Selective loss of hippocampal granule cells following adrenalectamy: implication for spatial memory by Conrad (1993)
10.1038/243516a0 / Nature / Environmentally-induced changes in the brains of elderly rats by Cummins (1973)
{'key': '10.1016/0166-4328(93)90134-C_BIB12', 'series-title': 'Biology and Behavior: Neurophysiology and Emotion', 'first-page': '161', 'article-title': 'Stimulation in infancy, emotional reactivity, and exploratory behavior', 'author': 'Denenberg', 'year': '1967'} / Biology and Behavior: Neurophysiology and Emotion / Stimulation in infancy, emotional reactivity, and exploratory behavior by Denenberg (1967)
10.1016/S0197-4580(88)80117-9 / Neurobiol. Aging / Age-dependent alterations in hippocampal synaptic plasticity: relation to memory disorders by deToledo (1988)
10.1016/0163-1047(92)90892-8 / Behav. Neural Biol. / The relationship between adrenal steroids and enrichment-induced brain growth by Devenport (1992)
{'key': '10.1016/0166-4328(93)90134-C_BIB15', 'first-page': '66', 'article-title': 'The aging brain—some enlightening and optimistic results', 'volume': '66', 'author': 'Diamond', 'year': '1978', 'journal-title': 'Am. Sci.'} / Am. Sci. / The aging brain—some enlightening and optimistic results by Diamond (1978)
10.1002/neu.480070108 / J. Neurobiol. / Effects of environment on morphology of rat cerebral cortex and hippocampus by Diamond (1976)
10.1002/jnr.490010203 / J. Neurosci. Res. / Differences in occipital cortical synapses from environmentally enriched, unpoverished and standard colony rats by Diamond (1975)
10.1016/0014-4886(85)90221-3 / Exp. Neurol. / Plasticity in the 904-day-old male rat cerebral cortex by Diamond (1985)
10.1093/geronj/27.3.358 / J. Gerontol. / The effect of cage environment upon avoidance responding of aged rats by Doty (1972)
{'key': '10.1016/0166-4328(93)90134-C_BIB20', 'first-page': '529', 'article-title': 'Endocrine influences on cerebral development', 'volume': '75', 'author': 'Eayrs', 'year': '1964', 'journal-title': 'Arch. Biol.'} / Arch. Biol. / Endocrine influences on cerebral development by Eayrs (1964)
10.1016/0304-3940(92)90494-R / Neurosci. Lett. / Increased expression of BDNF mRNA in the hippocampus is associated with spatial learning and enriched environment by Falkenberg (1992)
10.1016/0014-4886(78)90229-7 / Exp. Neurol. / Environmental complexity modulates growth of granule cells dendrites in developing but not adult hippocampus of rats by Fiala (1978)
10.1037/h0053731 / J. Comp. Physiol. Psychol. / The nature of the effect of the free-environment experience in the rat by Forgays (1952)
10.1016/0006-8993(86)91486-1 / Brain Res. / Aged rats need a perforated axospinous synapses per hippocampal neuron to maintain good spatial memory by Geinisman (1986)
10.1037/h0033910 / J. Comp. Physiol. Psychol. / Effects of differential experience on dendritic spine counts in rat cerebral cortex by Globus (1973)
10.3758/BF03328961 / Psychon. Sci. / Effects of isolation, daily handling, and enriched rearing on maze learning by Greenough (1972)
10.1016/0006-8993(86)91437-X / Brain Res. / Environmental conditions modulate degeneration and new dendrite growth in cerebellum of senescent rats by Greenough (1986)
10.1016/0361-9230(80)90276-2 / Brain Res. Bull. / Paradoxical sleep and memory. I. Selective alterations following enriched and impoverished environmental rearing by Gutwein (1980)
{'key': '10.1016/0166-4328(93)90134-C_BIB29', 'series-title': 'The Organisation of Behavior', 'author': 'Hebb', 'year': '1949'} / The Organisation of Behavior by Hebb (1949)
10.1016/S0166-4328(05)80134-2 / Behav. Brain Res. / Hippocampal nerve growth factor levels are related to spatial learning in aged rats by Henriksson (1992)
10.1016/0031-9384(69)90023-7 / Physiol. Behav. / Modification of the corticosterone response curve as a function of handling in infancy by Hess (1969)
{'key': '10.1016/0166-4328(93)90134-C_BIB32', 'article-title': 'Effect of adrenalectomy on 5-HT and corticosteroid receptor subtype mRNA expression in the rat anterior hippocampus', 'volume': '128.8', 'author': 'Holmes', 'year': '1993'} / Effect of adrenalectomy on 5-HT and corticosteroid receptor subtype mRNA expression in the rat anterior hippocampus by Holmes (1993)
10.1037/h0061535 / J. Comp. Physiol. Psychol. / The effects of experimental variations on problem solving in the rat by Hymovitch (1952)
10.1523/JNEUROSCI.10-10-03247.1990 / J. Neurosci. / Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats by Issa (1990)
10.1016/S0163-1047(80)91017-1 / Behav. Neural Biol. / Morphological analysis of the hippocampus following differential rearing in environments of varying social and physical complexity by Jones (1980)
{'key': '10.1016/0166-4328(93)90134-C_BIB36', 'series-title': 'The Cerebral Cortex of the Rat', 'first-page': '483', 'article-title': 'The structure of the cerebral cortex: effects of gender and the environment', 'author': 'Juraska', 'year': '1990'} / The Cerebral Cortex of the Rat / The structure of the cerebral cortex: effects of gender and the environment by Juraska (1990)
10.1016/0006-8993(85)90125-8 / Brain Res. / Sex differences in the dendritic branching of dentate granule cells following differential experience by Juraska (1985)
10.1016/0006-8993(89)91341-3 / Brain Res. / The dendritic morphology of pyramidal neurons in the rat hippocampal CA3 area. II. Effects of gender and experience by Juraska (1989)
10.1016/0006-8993(90)91178-J / Brain Res. / Age related changes in the rat hippocampus: correlation with working memory deficiency by Kadar (1990)
10.1016/0031-9384(81)90164-5 / Physiol. Behav. / Effects of rearing environments upon sleep-wake patterns in rats by Kiyono (1981)
10.1016/0031-9384(66)90051-5 / Physiol. Behav. / Environmental impoverishment, social isolation and changes in brain chemistry and anatomy by Kretch (1966)
10.1126/science.6270791 / Science / Brain aging correlates: retardation by hormonal-pharmacological treatments by Landfield (1981)
10.1016/0006-8993(78)90655-8 / Brain Res. / Impaired synaptic potentiation processes in the hippocampus of aged, memory-deficient rats by Landfield (1978)
{'key': '10.1016/0166-4328(93)90134-C_BIB44', 'article-title': 'Postnatal handling in the rat alters hippocampal glucocorticoid receptor gene expression', 'volume': '204.7', 'author': 'LaRocque', 'year': '1992', 'journal-title': 'Soc. Neurosci. Abstr.'} / Soc. Neurosci. Abstr. / Postnatal handling in the rat alters hippocampal glucocorticoid receptor gene expression by LaRocque (1992)
10.1111/j.1467-6494.1956.tb01289.x / J. Pers. / A further study of infantile handling and adult avoidance learning by Levine (1956)
10.1126/science.126.3270.405 / Science / Infantile experience and resistance to physiological stress by Levine (1957)
{'key': '10.1016/0166-4328(93)90134-C_BIB47', 'first-page': '81', 'article-title': 'Stimulation in infancy', 'volume': '20', 'author': 'Levine', 'year': '1960', 'journal-title': 'Scient. Am.'} / Scient. Am. / Stimulation in infancy by Levine (1960)
10.1016/0031-9384(67)90011-X / Physiol. Behav. / Physiological and behavioral effects of infantile stimulation by Levine (1967)
{'key': '10.1016/0166-4328(93)90134-C_BIB49', 'series-title': 'World Culture and the Black Experience', 'author': 'Mazrui', 'year': '1974'} / World Culture and the Black Experience by Mazrui (1974)
10.1016/0006-8993(73)90143-1 / Brain Res. / Corticosterone binding to hippocampus: nuclear and cytosol binding in vitro by McEwen (1973)
10.1016/0165-3806(85)90183-X / Dev. Brain Res. / The effect of early postnatal handling on the development of hippocampal glucocorticoid receptors: temporal parameters by Meaney (1985)
10.1126/science.3340858 / Science / Postnatal handling attenuates neuroendocrine, anatomical, and cognitive impairments related to the aged hippocampus by Meaney (1988)
10.1159/000125287 / Neuroendocrinology / Postnatal handling increases hippocampal type II. glucocorticoid receptors and enhances adrenocortical negative-feedback efficacy in the rat by Meaney (1989)
10.1016/0197-4580(91)90036-J / Neurobiol. Aging / Postnatal handling attenuates certain neuroendocrine, anatomical, and cognitive dysfunctions associated with aging in female rats by Meaney (1991)
10.1016/0306-4530(91)90072-2 / Psychoneuroendocrinology / The effects of neonatal handling on the development of the adrenocortical response to stress: implications for neuropathology and cognitive deficits in later life by Meaney (1991)
10.1016/0006-8993(82)91203-3 / Brain Res. / Sleep patterns during rearing under different environmental conditions in juvenile rats by Mirmiran (1982)
10.1016/S0079-6123(08)64321-6 / Prog. Brain Res. / Enviromental influences on brain and behavior in aging and Alzheimer's disease by Mirmiran (1986)
10.1016/0006-8993(86)91243-6 / Brain Res. / Selective lesioning of forebrain noradrenaline neurones abolishes the improved maze learning performance induced by rearing in complex environment by Mohammed (1986)
{'key': '10.1016/0166-4328(93)90134-C_BIB59', 'article-title': 'Environmental influence on behaviour and nerve growth factor in the brain', 'volume': '62–72', 'author': 'Mohammed', 'year': '1990', 'journal-title': 'Brain Res.'} / Brain Res. / Environmental influence on behaviour and nerve growth factor in the brain by Mohammed (1990)
Nilsson, L., Mohammed, A.H., Henriksson, B.G., Folkesson, R., Winblad, B. and Bergström, L., Environmental influence on somatostatin levels and gene expression in the rat brain. Brain Res., in press. (10.1016/0006-8993(93)90942-G)
10.1002/dev.420250304 / Dev. Psychobiol. / Neonatal 6-OHDA lesions and rearing in complex environments: regional effects on adult brain 14C-2-deoxyglucose uptake revealed by exposure to novel stimulation by Norbrega (1992)
Olsson, T., Mohammed, A.K., French, K.L. and Seckl, J.R., NGFIA and glucocorticoid receptor mRNA expression is induced in the hippocampus after environmental enrichment in adult rats, Soc. Neurosci. Abstr., in press.
10.1016/0304-3940(92)90278-F / Neurosci. Lett. / Enriched environment primes forebrain cholme acetyltransferase activity to respond to learning experience by Park (1992)
10.1037/0735-7036.101.1.94 / J. Comp. Psychol. / Experience-dependent changes in exploratory behaviour in the adult rat (Rattus norvegicus): overall activity level and with objects by Renner (1987)
10.1037/0735-7036.100.3.229 / J. Comp. Physiol. Psychol. / Object interactions in juvenile rats (Rattus norvegicus): effects of different experiential histories by Renner (1986)
10.1210/endo-117-6-2505 / Endocrinology / Two receptor stystems for corticosterone in rat brain: microdistribution and differential occupation by Reul (1985)
10.1016/0022-4731(86)90063-4 / J. Steroid Biochem. / Anatomical resolution of two types of corticosterone reeeptor sites in the rat brain with in vitro autoradiography and computerized image analysis by Reul (1986)
10.1016/0006-8993(84)90612-7 / Brain Res. / Spatial orientation and hippocampal corticosterone receptor systems of old rats: effect of ACTH 4–9 analogue ORG2766 by Rigter (1984)
10.1016/0166-4328(87)90057-X / Behav. Brain Res. / Environmental enrichment and recovery from contralateral sensory neglect in rats with large unilateral neocortical lesions by Rose (1987)
10.1097/00001756-199302000-00012 / Neuroreport / How does environmental enrichment aid recovery following cortical injury in the rat? by Rose (1993)
10.1016/0166-4328(93)90025-L / Behav. Brain Res. / Environmental enrichment following brain damage: an aid to recovery or compensation? by Rose (1993)
{'key': '10.1016/0166-4328(93)90134-C_BIB72', 'series-title': 'Development and Evolution of Brain Size: Behavioral Implications', 'first-page': '263', 'article-title': 'Responsiveness of brain size to individual experience: behavioural and evolutionary implications', 'author': 'Rosenzweig', 'year': '1979'} / Development and Evolution of Brain Size: Behavioral Implications / Responsiveness of brain size to individual experience: behavioural and evolutionary implications by Rosenzweig (1979)
10.1002/dev.420020208 / Dev. Psychobiol. / Effects of differential environments on brain weights and enzyme activities in gerbils, rats and mice by Rosenzweig (1969)
10.1016/B978-0-12-609304-9.50019-X / Studies on the Development of Behavior and the Nervous System / Experiential influences on brain anatomy and brain chemistry in rodents by Rosenzweig (1978)
10.1037/h0032527 / J. Comp. Physiol. Psychol. / Cerebral effects of differential experience in hypophysectomized rats by Rosenzweig (1972)
10.1016/0892-0362(90)90109-P / Neurotoxicol. Teratol. / Enriched housing masks deficits in place navigation induced by neonatal monosodium glutamate by Saari (1990)
{'key': '10.1016/0166-4328(93)90134-C_BIB77', 'series-title': 'Stress, The Aging Brain and Mechanism of Neuronal Death', 'author': 'Sapolsky', 'year': '1992'} / Stress, The Aging Brain and Mechanism of Neuronal Death by Sapolsky (1992)
10.1016/0006-8993(83)90024-0 / Brain Res. / Corticosterone receptors decline in a site specific manner in the aged rat brain by Sapolsky (1983)
10.1523/JNEUROSCI.05-05-01222.1985 / J. Neurosci. / Prolonged glucocorticoid exposure reduced hippocampal neuron number: implications for aging by Sapolsky (1985)
10.1210/edrv-7-3-284 / Endocr. Rev. / The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis by Sapolsky (1986)
10.1016/0014-4886(91)90041-A / Exp. Neurol. / Long-term adrenalectomy causes loss of dentate gyrus and pyramidal neurons in the adult hippocampus by Sapolsky (1991)
10.1016/0016-6480(68)90028-2 / Gen. Comp. Endocr. / Some physiological, biochemical, and behavioral consequences of neonatal hormone administration: cortisol and thyroxine by Schapiro (1968)
10.1037/h0045518 / J. Comp. Physiol. Psychol. / Effect of neonatal cortical lesions and early environmental factors on adult rat behavior by Schwartz (1964)
10.1016/0031-9384(81)90045-7 / Physiol. Behav. / Environmental enrichment alleviates maze performance deficits in rats with microcephaly induced by X-irradiation by Shibagaki (1981)
10.1016/0014-4886(91)90052-E / Exp. Neurol. / Astrocyte hypertrophy in the dentate gyrus of young male rats reflect variation of individual stress rather than group environmental complexity manipulation by Sirevaag (1991)
10.1126/science.2911756 / Science / Selective loss of hippocampal granule cells in the mature rat brain after adrenalectomy by Sloviter (1989)
10.1002/cne.903300304 / J. Comp. Neurol. / Adrenalectomy-induced granule cell degeneraation in the rat hippocampal dentate gyrus: characterization of an in vivo model of controlled neuronal death by Sloviter (1993)
10.1002/jnr.490270427 / J. Neurosci. Res. / Recombinant human β-nerve growth factor (NGF): biological activity and properties in an enzyme immunoassay by Söderström (1990)
10.1037/0033-295X.99.2.195 / Psychol. Rev. / Memory and the hippocampus: a synthesis from findings with rats, monkeys and humans by Squire (1992)
10.1093/icb/11.4.725 / Am. Zool. / Autoradiographic techniques and the localization of estrogen, androgen and glucocorticoid in the pituitary and brain by Stumpf (1971)
10.1016/0197-4580(91)90008-8 / Neurobiol. Aging / Brain aging and Alzheimer's disease, “wear and tear” versus “use it or lose it” by Swaab (1991)
{'key': '10.1016/0166-4328(93)90134-C_BIB92', 'first-page': '239', 'article-title': 'Synapses per neuron and synaptic dimensions in occipital cortex of rats reared in complex, social, or isolation housing', 'volume': '2', 'author': 'Turner', 'year': '1983', 'journal-title': 'Acta Stereolog.'} / Acta Stereolog. / Synapses per neuron and synaptic dimensions in occipital cortex of rats reared in complex, social, or isolation housing by Turner (1983)
10.1037/0033-2909.88.1.215 / Psychol. Bull. / Reevaluation of mechanisms that mediate brain differences between enriched and impoverished animals by Uphouse (1980)
10.1093/sleep/9.2.335 / Sleep / Effects of aging and housing in an enriched environment on sleep-wake patterns in rats by Van Gool (1986)
10.1126/science.176.4042.1445 / Science / Rearing complexity affects branching of dendrites in the visual cortex of rat by Volkmar (1972)
10.1037/0033-2909.82.6.986 / Psychol. Bull. / Mechanisms mediating the production of environmentally induced brain changes by Walsh (1975)
10.1002/cne.901370309 / J. Comp. Neurol. / The effects of environmental complexity on the histology of the rat hippocampus by Walsh (1969)
10.1016/S0091-6773(72)80207-4 / Behav. Biol. / Effect of environmental complexity on cortical synapses of rats by West (1972)
{'key': '10.1016/0166-4328(93)90134-C_BIB99', 'series-title': 'Recovery From Brain Damage: Reflections And Directions', 'first-page': '79', 'article-title': 'Environmental approaches to recovery of function from brain damage: a review of animal studies (1981 to 1991)', 'author': 'Will', 'year': '1992'} / Recovery From Brain Damage: Reflections And Directions / Environmental approaches to recovery of function from brain damage: a review of animal studies (1981 to 1991) by Will (1992)
10.1016/0031-9384(76)90221-3 / Physiol. Behav. / Effects of differential environments on recovery from neonatal brain lesions, measured by problem-solving scores by Will (1976)
10.1037/h0077306 / J. Comp. Physiol. Psychol. / Relatively brief environment enrichment aids recovery of learning capacity and alters brain measures after postweaning brain lesion by Will (1977)
{'key': '10.1016/0166-4328(93)90134-C_BIB102', 'article-title': 'Induction of the immediate early gene zif-268 in the cortex and hippocampal formation of weanling rats after brief exposure to environmental complexity', 'volume': '56.11', 'author': 'Withers', 'year': '1991', 'journal-title': 'Soc. Neurosci. Abstr.'} / Soc. Neurosci. Abstr. / Induction of the immediate early gene zif-268 in the cortex and hippocampal formation of weanling rats after brief exposure to environmental complexity by Withers (1991)

Dates

Type	When
Created	22 years, 4 months ago (April 24, 2003, 1:34 p.m.)
Deposited	5 years, 5 months ago (March 18, 2020, 11:38 a.m.)
Indexed	3 months ago (May 24, 2025, 4:04 a.m.)
Issued	31 years, 9 months ago (Nov. 1, 1993)
Published	31 years, 9 months ago (Nov. 1, 1993)
Published Print	31 years, 9 months ago (Nov. 1, 1993)

Funders 0

None

BibTeX

@article{Mohammed_1993, title={Environmental influences on the central nervous system and their implications for the aging rat}, volume={57}, ISSN={0166-4328}, url={http://dx.doi.org/10.1016/0166-4328(93)90134-c}, DOI={10.1016/0166-4328(93)90134-c}, number={2}, journal={Behavioural Brain Research}, publisher={Elsevier BV}, author={Mohammed, Abdul H. and Henriksson, Bengt G. and Söderström, Stine and Ebendal, Ted and Olsson, Tommy and Seckl, Jonathan R.}, year={1993}, month=nov, pages={183–191} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        5,
        24
      ]
    ],
    "date-time": "2025-05-24T08:04:01Z",
    "timestamp": 1748073841711
  },
  "reference-count": 102,
  "publisher": "Elsevier BV",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1993,
            11,
            1
          ]
        ],
        "date-time": "1993-11-01T00:00:00Z",
        "timestamp": 752112000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1993,
        11
      ]
    ]
  },
  "DOI": "10.1016/0166-4328(93)90134-c",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2003,
        4,
        24
      ]
    ],
    "date-time": "2003-04-24T17:34:16Z",
    "timestamp": 1051205656000
  },
  "page": "183-191",
  "source": "Crossref",
  "is-referenced-by-count": 158,
  "title": "Environmental influences on the central nervous system and their implications for the aging rat",
  "prefix": "10.1016",
  "volume": "57",
  "author": [
    {
      "given": "Abdul H.",
      "family": "Mohammed",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Bengt G.",
      "family": "Henriksson",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Stine",
      "family": "S\u00f6derstr\u00f6m",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Ted",
      "family": "Ebendal",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Tommy",
      "family": "Olsson",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Jonathan R.",
      "family": "Seckl",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "303",
      "DOI": "10.1016/0031-9384(69)90179-6",
      "article-title": "Effects of early experience on adrenocortical reactivity",
      "volume": "4",
      "author": "Ader",
      "year": "1969",
      "journal-title": "Physiol. Behav."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB2",
      "unstructured": "Alridge, J. and Seckl, J.R., Quantitation of emulsion autoradiography in situ hybridization using image analysis and rate of change filters, J. Anat., in press."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB3",
      "series-title": "Physiology and Cell Biology of Aging",
      "first-page": "141",
      "article-title": "Brain plasticity, memory and aging",
      "author": "Bennett",
      "year": "1979"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "610",
      "DOI": "10.1126/science.146.3644.610",
      "article-title": "Chemical and anatomical plasticity of brain",
      "volume": "146",
      "author": "Bennett",
      "year": "1964",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "825",
      "DOI": "10.1126/science.163.3869.825",
      "article-title": "Rat brain: effects of environmental enrichment on wet and dry weights",
      "volume": "163",
      "author": "Bennett",
      "year": "1969",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB6",
      "series-title": "Molecular Approaches to Learning",
      "first-page": "55",
      "article-title": "Time course of effects of differential experience on brain measures and behavior of rats",
      "author": "Bennett",
      "year": "1970"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "307",
      "DOI": "10.1037/h0062513",
      "article-title": "The effect of different environments during infancy on adult behavior in the rat",
      "volume": "45",
      "author": "Bingham",
      "year": "1952",
      "journal-title": "J. Comp. Physiol. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "727",
      "DOI": "10.1002/dev.420220707",
      "article-title": "Effects of complex experience on somatic growth and organ development in rats",
      "volume": "22",
      "author": "Black",
      "year": "1989",
      "journal-title": "Dev. Psychobiol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "325",
      "DOI": "10.1016/0197-4580(91)90009-9",
      "article-title": "Usual vs. successful aging: some notes on experiential factors",
      "volume": "12",
      "author": "Black",
      "year": "1991",
      "journal-title": "Neurobiol. Aging"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "2582",
      "DOI": "10.1523/JNEUROSCI.13-06-02582.1993",
      "article-title": "Selective loss of hippocampal granule cells following adrenalectamy: implication for spatial memory",
      "volume": "13",
      "author": "Conrad",
      "year": "1993",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "516",
      "DOI": "10.1038/243516a0",
      "article-title": "Environmentally-induced changes in the brains of elderly rats",
      "volume": "243",
      "author": "Cummins",
      "year": "1973",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB12",
      "series-title": "Biology and Behavior: Neurophysiology and Emotion",
      "first-page": "161",
      "article-title": "Stimulation in infancy, emotional reactivity, and exploratory behavior",
      "author": "Denenberg",
      "year": "1967"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "581",
      "DOI": "10.1016/S0197-4580(88)80117-9",
      "article-title": "Age-dependent alterations in hippocampal synaptic plasticity: relation to memory disorders",
      "volume": "9",
      "author": "deToledo",
      "year": "1988",
      "journal-title": "Neurobiol. Aging"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "45",
      "DOI": "10.1016/0163-1047(92)90892-8",
      "article-title": "The relationship between adrenal steroids and enrichment-induced brain growth",
      "volume": "58",
      "author": "Devenport",
      "year": "1992",
      "journal-title": "Behav. Neural Biol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB15",
      "first-page": "66",
      "article-title": "The aging brain\u2014some enlightening and optimistic results",
      "volume": "66",
      "author": "Diamond",
      "year": "1978",
      "journal-title": "Am. Sci."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "75",
      "DOI": "10.1002/neu.480070108",
      "article-title": "Effects of environment on morphology of rat cerebral cortex and hippocampus",
      "volume": "7",
      "author": "Diamond",
      "year": "1976",
      "journal-title": "J. Neurobiol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "109",
      "DOI": "10.1002/jnr.490010203",
      "article-title": "Differences in occipital cortical synapses from environmentally enriched, unpoverished and standard colony rats",
      "volume": "1",
      "author": "Diamond",
      "year": "1975",
      "journal-title": "J. Neurosci. Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "309",
      "DOI": "10.1016/0014-4886(85)90221-3",
      "article-title": "Plasticity in the 904-day-old male rat cerebral cortex",
      "volume": "87",
      "author": "Diamond",
      "year": "1985",
      "journal-title": "Exp. Neurol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "358",
      "DOI": "10.1093/geronj/27.3.358",
      "article-title": "The effect of cage environment upon avoidance responding of aged rats",
      "volume": "27",
      "author": "Doty",
      "year": "1972",
      "journal-title": "J. Gerontol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB20",
      "first-page": "529",
      "article-title": "Endocrine influences on cerebral development",
      "volume": "75",
      "author": "Eayrs",
      "year": "1964",
      "journal-title": "Arch. Biol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "153",
      "DOI": "10.1016/0304-3940(92)90494-R",
      "article-title": "Increased expression of BDNF mRNA in the hippocampus is associated with spatial learning and enriched environment",
      "volume": "138",
      "author": "Falkenberg",
      "year": "1992",
      "journal-title": "Neurosci. Lett."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "372",
      "DOI": "10.1016/0014-4886(78)90229-7",
      "article-title": "Environmental complexity modulates growth of granule cells dendrites in developing but not adult hippocampus of rats",
      "volume": "59",
      "author": "Fiala",
      "year": "1978",
      "journal-title": "Exp. Neurol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "322",
      "DOI": "10.1037/h0053731",
      "article-title": "The nature of the effect of the free-environment experience in the rat",
      "volume": "45",
      "author": "Forgays",
      "year": "1952",
      "journal-title": "J. Comp. Physiol. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "266",
      "DOI": "10.1016/0006-8993(86)91486-1",
      "article-title": "Aged rats need a perforated axospinous synapses per hippocampal neuron to maintain good spatial memory",
      "volume": "398",
      "author": "Geinisman",
      "year": "1986",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "175",
      "DOI": "10.1037/h0033910",
      "article-title": "Effects of differential experience on dendritic spine counts in rat cerebral cortex",
      "volume": "82",
      "author": "Globus",
      "year": "1973",
      "journal-title": "J. Comp. Physiol. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "279",
      "DOI": "10.3758/BF03328961",
      "article-title": "Effects of isolation, daily handling, and enriched rearing on maze learning",
      "volume": "27",
      "author": "Greenough",
      "year": "1972",
      "journal-title": "Psychon. Sci."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "136",
      "DOI": "10.1016/0006-8993(86)91437-X",
      "article-title": "Environmental conditions modulate degeneration and new dendrite growth in cerebellum of senescent rats",
      "volume": "380",
      "author": "Greenough",
      "year": "1986",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "9",
      "DOI": "10.1016/0361-9230(80)90276-2",
      "article-title": "Paradoxical sleep and memory. I. Selective alterations following enriched and impoverished environmental rearing",
      "volume": "5",
      "author": "Gutwein",
      "year": "1980",
      "journal-title": "Brain Res. Bull."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB29",
      "series-title": "The Organisation of Behavior",
      "author": "Hebb",
      "year": "1949"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "15",
      "DOI": "10.1016/S0166-4328(05)80134-2",
      "article-title": "Hippocampal nerve growth factor levels are related to spatial learning in aged rats",
      "volume": "48",
      "author": "Henriksson",
      "year": "1992",
      "journal-title": "Behav. Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "109",
      "DOI": "10.1016/0031-9384(69)90023-7",
      "article-title": "Modification of the corticosterone response curve as a function of handling in infancy",
      "volume": "4",
      "author": "Hess",
      "year": "1969",
      "journal-title": "Physiol. Behav."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB32",
      "article-title": "Effect of adrenalectomy on 5-HT and corticosteroid receptor subtype mRNA expression in the rat anterior hippocampus",
      "volume": "128.8",
      "author": "Holmes",
      "year": "1993"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "313",
      "DOI": "10.1037/h0061535",
      "article-title": "The effects of experimental variations on problem solving in the rat",
      "volume": "45",
      "author": "Hymovitch",
      "year": "1952",
      "journal-title": "J. Comp. Physiol. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "3247",
      "DOI": "10.1523/JNEUROSCI.10-10-03247.1990",
      "article-title": "Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats",
      "volume": "10",
      "author": "Issa",
      "year": "1990",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "135",
      "DOI": "10.1016/S0163-1047(80)91017-1",
      "article-title": "Morphological analysis of the hippocampus following differential rearing in environments of varying social and physical complexity",
      "volume": "30",
      "author": "Jones",
      "year": "1980",
      "journal-title": "Behav. Neural Biol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB36",
      "series-title": "The Cerebral Cortex of the Rat",
      "first-page": "483",
      "article-title": "The structure of the cerebral cortex: effects of gender and the environment",
      "author": "Juraska",
      "year": "1990"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "73",
      "DOI": "10.1016/0006-8993(85)90125-8",
      "article-title": "Sex differences in the dendritic branching of dentate granule cells following differential experience",
      "volume": "333",
      "author": "Juraska",
      "year": "1985",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "115",
      "DOI": "10.1016/0006-8993(89)91341-3",
      "article-title": "The dendritic morphology of pyramidal neurons in the rat hippocampal CA3 area. II. Effects of gender and experience",
      "volume": "79",
      "author": "Juraska",
      "year": "1989",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "113",
      "DOI": "10.1016/0006-8993(90)91178-J",
      "article-title": "Age related changes in the rat hippocampus: correlation with working memory deficiency",
      "volume": "512",
      "author": "Kadar",
      "year": "1990",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "391",
      "DOI": "10.1016/0031-9384(81)90164-5",
      "article-title": "Effects of rearing environments upon sleep-wake patterns in rats",
      "volume": "26",
      "author": "Kiyono",
      "year": "1981",
      "journal-title": "Physiol. Behav."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "99",
      "DOI": "10.1016/0031-9384(66)90051-5",
      "article-title": "Environmental impoverishment, social isolation and changes in brain chemistry and anatomy",
      "volume": "1",
      "author": "Kretch",
      "year": "1966",
      "journal-title": "Physiol. Behav."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "581",
      "DOI": "10.1126/science.6270791",
      "article-title": "Brain aging correlates: retardation by hormonal-pharmacological treatments",
      "volume": "214",
      "author": "Landfield",
      "year": "1981",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "85",
      "DOI": "10.1016/0006-8993(78)90655-8",
      "article-title": "Impaired synaptic potentiation processes in the hippocampus of aged, memory-deficient rats",
      "volume": "150",
      "author": "Landfield",
      "year": "1978",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB44",
      "article-title": "Postnatal handling in the rat alters hippocampal glucocorticoid receptor gene expression",
      "volume": "204.7",
      "author": "LaRocque",
      "year": "1992",
      "journal-title": "Soc. Neurosci. Abstr."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "70",
      "DOI": "10.1111/j.1467-6494.1956.tb01289.x",
      "article-title": "A further study of infantile handling and adult avoidance learning",
      "volume": "25",
      "author": "Levine",
      "year": "1956",
      "journal-title": "J. Pers."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "405",
      "DOI": "10.1126/science.126.3270.405",
      "article-title": "Infantile experience and resistance to physiological stress",
      "volume": "126",
      "author": "Levine",
      "year": "1957",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB47",
      "first-page": "81",
      "article-title": "Stimulation in infancy",
      "volume": "20",
      "author": "Levine",
      "year": "1960",
      "journal-title": "Scient. Am."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "55",
      "DOI": "10.1016/0031-9384(67)90011-X",
      "article-title": "Physiological and behavioral effects of infantile stimulation",
      "volume": "2",
      "author": "Levine",
      "year": "1967",
      "journal-title": "Physiol. Behav."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB49",
      "series-title": "World Culture and the Black Experience",
      "author": "Mazrui",
      "year": "1974"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "373",
      "DOI": "10.1016/0006-8993(73)90143-1",
      "article-title": "Corticosterone binding to hippocampus: nuclear and cytosol binding in vitro",
      "volume": "57",
      "author": "McEwen",
      "year": "1973",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "301",
      "DOI": "10.1016/0165-3806(85)90183-X",
      "article-title": "The effect of early postnatal handling on the development of hippocampal glucocorticoid receptors: temporal parameters",
      "volume": "22",
      "author": "Meaney",
      "year": "1985",
      "journal-title": "Dev. Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "766",
      "DOI": "10.1126/science.3340858",
      "article-title": "Postnatal handling attenuates neuroendocrine, anatomical, and cognitive impairments related to the aged hippocampus",
      "volume": "238",
      "author": "Meaney",
      "year": "1988",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "597",
      "DOI": "10.1159/000125287",
      "article-title": "Postnatal handling increases hippocampal type II. glucocorticoid receptors and enhances adrenocortical negative-feedback efficacy in the rat",
      "volume": "50",
      "author": "Meaney",
      "year": "1989",
      "journal-title": "Neuroendocrinology"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "31",
      "DOI": "10.1016/0197-4580(91)90036-J",
      "article-title": "Postnatal handling attenuates certain neuroendocrine, anatomical, and cognitive dysfunctions associated with aging in female rats",
      "volume": "12",
      "author": "Meaney",
      "year": "1991",
      "journal-title": "Neurobiol. Aging"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "85",
      "DOI": "10.1016/0306-4530(91)90072-2",
      "article-title": "The effects of neonatal handling on the development of the adrenocortical response to stress: implications for neuropathology and cognitive deficits in later life",
      "volume": "16",
      "author": "Meaney",
      "year": "1991",
      "journal-title": "Psychoneuroendocrinology"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "287",
      "DOI": "10.1016/0006-8993(82)91203-3",
      "article-title": "Sleep patterns during rearing under different environmental conditions in juvenile rats",
      "volume": "233",
      "author": "Mirmiran",
      "year": "1982",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB57",
      "doi-asserted-by": "crossref",
      "first-page": "443",
      "DOI": "10.1016/S0079-6123(08)64321-6",
      "article-title": "Enviromental influences on brain and behavior in aging and Alzheimer's disease",
      "volume": "70",
      "author": "Mirmiran",
      "year": "1986",
      "journal-title": "Prog. Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "6",
      "DOI": "10.1016/0006-8993(86)91243-6",
      "article-title": "Selective lesioning of forebrain noradrenaline neurones abolishes the improved maze learning performance induced by rearing in complex environment",
      "volume": "398",
      "author": "Mohammed",
      "year": "1986",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB59",
      "article-title": "Environmental influence on behaviour and nerve growth factor in the brain",
      "volume": "62\u201372",
      "author": "Mohammed",
      "year": "1990",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB60",
      "doi-asserted-by": "crossref",
      "unstructured": "Nilsson, L., Mohammed, A.H., Henriksson, B.G., Folkesson, R., Winblad, B. and Bergstr\u00f6m, L., Environmental influence on somatostatin levels and gene expression in the rat brain. Brain Res., in press.",
      "DOI": "10.1016/0006-8993(93)90942-G"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB61",
      "doi-asserted-by": "crossref",
      "first-page": "183",
      "DOI": "10.1002/dev.420250304",
      "article-title": "Neonatal 6-OHDA lesions and rearing in complex environments: regional effects on adult brain 14C-2-deoxyglucose uptake revealed by exposure to novel stimulation",
      "volume": "25",
      "author": "Norbrega",
      "year": "1992",
      "journal-title": "Dev. Psychobiol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB62",
      "unstructured": "Olsson, T., Mohammed, A.K., French, K.L. and Seckl, J.R., NGFIA and glucocorticoid receptor mRNA expression is induced in the hippocampus after environmental enrichment in adult rats, Soc. Neurosci. Abstr., in press."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB63",
      "doi-asserted-by": "crossref",
      "first-page": "259",
      "DOI": "10.1016/0304-3940(92)90278-F",
      "article-title": "Enriched environment primes forebrain cholme acetyltransferase activity to respond to learning experience",
      "volume": "143",
      "author": "Park",
      "year": "1992",
      "journal-title": "Neurosci. Lett."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB64",
      "doi-asserted-by": "crossref",
      "first-page": "94",
      "DOI": "10.1037/0735-7036.101.1.94",
      "article-title": "Experience-dependent changes in exploratory behaviour in the adult rat (Rattus norvegicus): overall activity level and with objects",
      "volume": "101",
      "author": "Renner",
      "year": "1987",
      "journal-title": "J. Comp. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB65",
      "doi-asserted-by": "crossref",
      "first-page": "229",
      "DOI": "10.1037/0735-7036.100.3.229",
      "article-title": "Object interactions in juvenile rats (Rattus norvegicus): effects of different experiential histories",
      "volume": "100",
      "author": "Renner",
      "year": "1986",
      "journal-title": "J. Comp. Physiol. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB66",
      "doi-asserted-by": "crossref",
      "first-page": "2505",
      "DOI": "10.1210/endo-117-6-2505",
      "article-title": "Two receptor stystems for corticosterone in rat brain: microdistribution and differential occupation",
      "volume": "117",
      "author": "Reul",
      "year": "1985",
      "journal-title": "Endocrinology"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB67",
      "doi-asserted-by": "crossref",
      "first-page": "269",
      "DOI": "10.1016/0022-4731(86)90063-4",
      "article-title": "Anatomical resolution of two types of corticosterone reeeptor sites in the rat brain with in vitro autoradiography and computerized image analysis",
      "volume": "25",
      "author": "Reul",
      "year": "1986",
      "journal-title": "J. Steroid Biochem."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB68",
      "doi-asserted-by": "crossref",
      "first-page": "393",
      "DOI": "10.1016/0006-8993(84)90612-7",
      "article-title": "Spatial orientation and hippocampal corticosterone receptor systems of old rats: effect of ACTH 4\u20139 analogue ORG2766",
      "volume": "309",
      "author": "Rigter",
      "year": "1984",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB69",
      "doi-asserted-by": "crossref",
      "first-page": "195",
      "DOI": "10.1016/0166-4328(87)90057-X",
      "article-title": "Environmental enrichment and recovery from contralateral sensory neglect in rats with large unilateral neocortical lesions",
      "volume": "24",
      "author": "Rose",
      "year": "1987",
      "journal-title": "Behav. Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB70",
      "doi-asserted-by": "crossref",
      "first-page": "163",
      "DOI": "10.1097/00001756-199302000-00012",
      "article-title": "How does environmental enrichment aid recovery following cortical injury in the rat?",
      "volume": "4",
      "author": "Rose",
      "year": "1993",
      "journal-title": "Neuroreport"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB71",
      "doi-asserted-by": "crossref",
      "first-page": "93",
      "DOI": "10.1016/0166-4328(93)90025-L",
      "article-title": "Environmental enrichment following brain damage: an aid to recovery or compensation?",
      "volume": "5",
      "author": "Rose",
      "year": "1993",
      "journal-title": "Behav. Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB72",
      "series-title": "Development and Evolution of Brain Size: Behavioral Implications",
      "first-page": "263",
      "article-title": "Responsiveness of brain size to individual experience: behavioural and evolutionary implications",
      "author": "Rosenzweig",
      "year": "1979"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB73",
      "doi-asserted-by": "crossref",
      "first-page": "87",
      "DOI": "10.1002/dev.420020208",
      "article-title": "Effects of differential environments on brain weights and enzyme activities in gerbils, rats and mice",
      "volume": "2",
      "author": "Rosenzweig",
      "year": "1969",
      "journal-title": "Dev. Psychobiol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB74",
      "series-title": "Studies on the Development of Behavior and the Nervous System",
      "doi-asserted-by": "crossref",
      "first-page": "289",
      "DOI": "10.1016/B978-0-12-609304-9.50019-X",
      "article-title": "Experiential influences on brain anatomy and brain chemistry in rodents",
      "author": "Rosenzweig",
      "year": "1978"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB75",
      "doi-asserted-by": "crossref",
      "first-page": "56",
      "DOI": "10.1037/h0032527",
      "article-title": "Cerebral effects of differential experience in hypophysectomized rats",
      "volume": "79",
      "author": "Rosenzweig",
      "year": "1972",
      "journal-title": "J. Comp. Physiol. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB76",
      "doi-asserted-by": "crossref",
      "first-page": "29",
      "DOI": "10.1016/0892-0362(90)90109-P",
      "article-title": "Enriched housing masks deficits in place navigation induced by neonatal monosodium glutamate",
      "volume": "1",
      "author": "Saari",
      "year": "1990",
      "journal-title": "Neurotoxicol. Teratol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB77",
      "series-title": "Stress, The Aging Brain and Mechanism of Neuronal Death",
      "author": "Sapolsky",
      "year": "1992"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB78",
      "doi-asserted-by": "crossref",
      "first-page": "235",
      "DOI": "10.1016/0006-8993(83)90024-0",
      "article-title": "Corticosterone receptors decline in a site specific manner in the aged rat brain",
      "volume": "289",
      "author": "Sapolsky",
      "year": "1983",
      "journal-title": "Brain Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB79",
      "doi-asserted-by": "crossref",
      "first-page": "1221",
      "DOI": "10.1523/JNEUROSCI.05-05-01222.1985",
      "article-title": "Prolonged glucocorticoid exposure reduced hippocampal neuron number: implications for aging",
      "volume": "5",
      "author": "Sapolsky",
      "year": "1985",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB80",
      "doi-asserted-by": "crossref",
      "first-page": "284",
      "DOI": "10.1210/edrv-7-3-284",
      "article-title": "The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis",
      "volume": "7",
      "author": "Sapolsky",
      "year": "1986",
      "journal-title": "Endocr. Rev."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB81",
      "doi-asserted-by": "crossref",
      "first-page": "246",
      "DOI": "10.1016/0014-4886(91)90041-A",
      "article-title": "Long-term adrenalectomy causes loss of dentate gyrus and pyramidal neurons in the adult hippocampus",
      "volume": "114",
      "author": "Sapolsky",
      "year": "1991",
      "journal-title": "Exp. Neurol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB82",
      "doi-asserted-by": "crossref",
      "first-page": "214",
      "DOI": "10.1016/0016-6480(68)90028-2",
      "article-title": "Some physiological, biochemical, and behavioral consequences of neonatal hormone administration: cortisol and thyroxine",
      "volume": "10",
      "author": "Schapiro",
      "year": "1968",
      "journal-title": "Gen. Comp. Endocr."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB83",
      "doi-asserted-by": "crossref",
      "first-page": "72",
      "DOI": "10.1037/h0045518",
      "article-title": "Effect of neonatal cortical lesions and early environmental factors on adult rat behavior",
      "volume": "57",
      "author": "Schwartz",
      "year": "1964",
      "journal-title": "J. Comp. Physiol. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB84",
      "doi-asserted-by": "crossref",
      "first-page": "72",
      "DOI": "10.1016/0031-9384(81)90045-7",
      "article-title": "Environmental enrichment alleviates maze performance deficits in rats with microcephaly induced by X-irradiation",
      "volume": "27",
      "author": "Shibagaki",
      "year": "1981",
      "journal-title": "Physiol. Behav."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB85",
      "doi-asserted-by": "crossref",
      "first-page": "74",
      "DOI": "10.1016/0014-4886(91)90052-E",
      "article-title": "Astrocyte hypertrophy in the dentate gyrus of young male rats reflect variation of individual stress rather than group environmental complexity manipulation",
      "volume": "111",
      "author": "Sirevaag",
      "year": "1991",
      "journal-title": "Exp. Neurol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB86",
      "doi-asserted-by": "crossref",
      "first-page": "535",
      "DOI": "10.1126/science.2911756",
      "article-title": "Selective loss of hippocampal granule cells in the mature rat brain after adrenalectomy",
      "volume": "243",
      "author": "Sloviter",
      "year": "1989",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB87",
      "doi-asserted-by": "crossref",
      "first-page": "324",
      "DOI": "10.1002/cne.903300304",
      "article-title": "Adrenalectomy-induced granule cell degeneraation in the rat hippocampal dentate gyrus: characterization of an in vivo model of controlled neuronal death",
      "volume": "330",
      "author": "Sloviter",
      "year": "1993",
      "journal-title": "J. Comp. Neurol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB88",
      "doi-asserted-by": "crossref",
      "first-page": "665",
      "DOI": "10.1002/jnr.490270427",
      "article-title": "Recombinant human \u03b2-nerve growth factor (NGF): biological activity and properties in an enzyme immunoassay",
      "volume": "27",
      "author": "S\u00f6derstr\u00f6m",
      "year": "1990",
      "journal-title": "J. Neurosci. Res."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB89",
      "doi-asserted-by": "crossref",
      "first-page": "195",
      "DOI": "10.1037/0033-295X.99.2.195",
      "article-title": "Memory and the hippocampus: a synthesis from findings with rats, monkeys and humans",
      "volume": "99",
      "author": "Squire",
      "year": "1992",
      "journal-title": "Psychol. Rev."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB90",
      "doi-asserted-by": "crossref",
      "first-page": "725",
      "DOI": "10.1093/icb/11.4.725",
      "article-title": "Autoradiographic techniques and the localization of estrogen, androgen and glucocorticoid in the pituitary and brain",
      "volume": "11",
      "author": "Stumpf",
      "year": "1971",
      "journal-title": "Am. Zool."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB91",
      "doi-asserted-by": "crossref",
      "first-page": "317",
      "DOI": "10.1016/0197-4580(91)90008-8",
      "article-title": "Brain aging and Alzheimer's disease, \u201cwear and tear\u201d versus \u201cuse it or lose it\u201d",
      "volume": "12",
      "author": "Swaab",
      "year": "1991",
      "journal-title": "Neurobiol. Aging"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB92",
      "first-page": "239",
      "article-title": "Synapses per neuron and synaptic dimensions in occipital cortex of rats reared in complex, social, or isolation housing",
      "volume": "2",
      "author": "Turner",
      "year": "1983",
      "journal-title": "Acta Stereolog."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB93",
      "doi-asserted-by": "crossref",
      "first-page": "215",
      "DOI": "10.1037/0033-2909.88.1.215",
      "article-title": "Reevaluation of mechanisms that mediate brain differences between enriched and impoverished animals",
      "volume": "88",
      "author": "Uphouse",
      "year": "1980",
      "journal-title": "Psychol. Bull."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB94",
      "doi-asserted-by": "crossref",
      "first-page": "335",
      "DOI": "10.1093/sleep/9.2.335",
      "article-title": "Effects of aging and housing in an enriched environment on sleep-wake patterns in rats",
      "volume": "9",
      "author": "Van Gool",
      "year": "1986",
      "journal-title": "Sleep"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB95",
      "doi-asserted-by": "crossref",
      "first-page": "1445",
      "DOI": "10.1126/science.176.4042.1445",
      "article-title": "Rearing complexity affects branching of dendrites in the visual cortex of rat",
      "volume": "176",
      "author": "Volkmar",
      "year": "1972",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB96",
      "doi-asserted-by": "crossref",
      "first-page": "986",
      "DOI": "10.1037/0033-2909.82.6.986",
      "article-title": "Mechanisms mediating the production of environmentally induced brain changes",
      "volume": "82",
      "author": "Walsh",
      "year": "1975",
      "journal-title": "Psychol. Bull."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB97",
      "doi-asserted-by": "crossref",
      "first-page": "361",
      "DOI": "10.1002/cne.901370309",
      "article-title": "The effects of environmental complexity on the histology of the rat hippocampus",
      "volume": "137",
      "author": "Walsh",
      "year": "1969",
      "journal-title": "J. Comp. Neurol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB98",
      "doi-asserted-by": "crossref",
      "first-page": "279",
      "DOI": "10.1016/S0091-6773(72)80207-4",
      "article-title": "Effect of environmental complexity on cortical synapses of rats",
      "volume": "7",
      "author": "West",
      "year": "1972",
      "journal-title": "Behav. Biol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB99",
      "series-title": "Recovery From Brain Damage: Reflections And Directions",
      "first-page": "79",
      "article-title": "Environmental approaches to recovery of function from brain damage: a review of animal studies (1981 to 1991)",
      "author": "Will",
      "year": "1992"
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB100",
      "doi-asserted-by": "crossref",
      "first-page": "603",
      "DOI": "10.1016/0031-9384(76)90221-3",
      "article-title": "Effects of differential environments on recovery from neonatal brain lesions, measured by problem-solving scores",
      "volume": "16",
      "author": "Will",
      "year": "1976",
      "journal-title": "Physiol. Behav."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB101",
      "doi-asserted-by": "crossref",
      "first-page": "33",
      "DOI": "10.1037/h0077306",
      "article-title": "Relatively brief environment enrichment aids recovery of learning capacity and alters brain measures after postweaning brain lesion",
      "volume": "91",
      "author": "Will",
      "year": "1977",
      "journal-title": "J. Comp. Physiol. Psychol."
    },
    {
      "key": "10.1016/0166-4328(93)90134-C_BIB102",
      "article-title": "Induction of the immediate early gene zif-268 in the cortex and hippocampal formation of weanling rats after brief exposure to environmental complexity",
      "volume": "56.11",
      "author": "Withers",
      "year": "1991",
      "journal-title": "Soc. Neurosci. Abstr."
    }
  ],
  "container-title": "Behavioural Brain Research",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:016643289390134C?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:016643289390134C?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2020,
        3,
        18
      ]
    ],
    "date-time": "2020-03-18T15:38:40Z",
    "timestamp": 1584545920000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/016643289390134C"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1993,
        11
      ]
    ]
  },
  "references-count": 102,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1993,
          11
        ]
      ]
    }
  },
  "alternative-id": [
    "016643289390134C"
  ],
  "URL": "http://dx.doi.org/10.1016/0166-4328(93)90134-C",
  "relation": {},
  "ISSN": [
    "0166-4328"
  ],
  "subject": [],
  "container-title-short": "Behavioural Brain Research",
  "published": {
    "date-parts": [
      [
        1993,
        11
      ]
    ]
  }
}