Crossref journal-article
Elsevier BV
Cell (78)
Bibliography

Imamoto, A., & Soriano, P. (1993). Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell, 73(6), 1117–1124.

Authors 2
  1. Akira Imamoto (first)
  2. Philippe Soriano (additional)
References 62 Referenced 315
  1. 10.1016/0092-8674(92)90309-Z / Cell / Defective T cell receptor signaling in mice lacking the thymic isoform of p59syn by Appleby (1992)
  2. 10.1038/349172a0 / Nature / Altered tyrosine 527 phosphorylation and mitotic activation of p60c-src by Bagrodia (1991)
  3. 10.1002/j.1460-2075.1992.tb05361.x / EMBO J. / The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity by Bergman (1992)
  4. 10.1016/0092-8674(84)90272-1 / Cell / Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation by Bolen (1984)
  5. {'key': '10.1016/0092-8674(93)90641-3_BIB5', 'first-page': '2251', 'article-title': 'Activation of pp60c-src protein kinase activity in human colon carcinoma', 'volume': '84', 'author': 'Bolen', 'year': '1987'} / Activation of pp60c-src protein kinase activity in human colon carcinoma by Bolen (1987)
  6. {'key': '10.1016/0092-8674(93)90641-3_BIB6', 'first-page': '149', 'article-title': 'Analysis of pp60c-src in human colon carcinoma and normal human colon mucosal cells', 'volume': '1', 'author': 'Bolen', 'year': '1987', 'journal-title': 'Oncogene Res.'} / Oncogene Res. / Analysis of pp60c-src in human colon carcinoma and normal human colon mucosal cells by Bolen (1987)
  7. 10.1242/dev.111.2.357 / Development / Expression of v-src induces aberrant development and twinning in chimaeric mice by Boulter (1991)
  8. 10.1016/0378-1119(92)90649-A / Gene / Isolation and characterization of a human gene that encodes a new subclass of protein tyrosine kinases by Bräuninger (1992)
  9. 10.1128/JVI.60.1.290-293.1986 / J. Virol. / A recombinant murine retrovirus for simian virus 40 large T DNA transforms mouse fibroblasts to anchorage-independent growth by Brown (1986)
  10. 10.1016/0092-8674(91)90639-G / Cell / Oncogenes and signal transduction by Cantley (1991)
  11. 10.1128/MCB.6.5.1562 / Mol. Cell. Biol. / Altered sites of tyrosine phosphorylation in pp60c-src associated with polyoma middle tumor antigen by Cartwright (1986)
  12. 10.1016/0092-8674(87)90758-6 / Cell / Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain by Cartwright (1987)
  13. {'key': '10.1016/0092-8674(93)90641-3_BIB13', 'first-page': '3348', 'article-title': 'pp60c-src expression in the developing rat brain', 'volume': '85', 'author': 'Cartwright', 'year': '1988'} / pp60c-src expression in the developing rat brain by Cartwright (1988)
  14. 10.1002/jez.1400700306 / J. Exp. Zool. / Development of the short-tailed mutant in the house mouse by Chesley (1935)
  15. {'key': '10.1016/0092-8674(93)90641-3_BIB15', 'series-title': 'Peptides and Protein Phosphorylation', 'first-page': '85', 'article-title': 'The src family of protein tyrosine kinases', 'author': 'Cooper', 'year': '1989'} / Peptides and Protein Phosphorylation / The src family of protein tyrosine kinases by Cooper (1989)
  16. 10.1128/MCB.6.12.4467 / Mol. Cell. Biol. / Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src by Cooper (1986)
  17. {'key': '10.1016/0092-8674(93)90641-3_BIB17', 'first-page': '4232', 'article-title': 'Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation', 'volume': '85', 'author': 'Cooper', 'year': '1988'} / Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation by Cooper (1988)
  18. {'key': '10.1016/0092-8674(93)90641-3_BIB18', 'first-page': '297', 'article-title': 'Avian pp60c-src is more active when expressed in yeast than in vertebrate fibroblasts', 'volume': '1', 'author': 'Cooper', 'year': '1987', 'journal-title': 'Oncogene Res.'} / Oncogene Res. / Avian pp60c-src is more active when expressed in yeast than in vertebrate fibroblasts by Cooper (1987)
  19. 10.1126/science.2420005 / Science / Tyr527 is phosphorylated in pp60c-src: implications for regulation by Cooper (1986)
  20. 10.1016/0301-0082(90)90037-H / Prog. Neurobiol. / The embryonic development of mammalian neural tube defects by Copp (1990)
  21. 10.1002/j.1460-2075.1985.tb03805.x / EMBO J. / Activation of pp60c-src kinase by middle T antigen binding or by dephosphorylation by Courtneidge (1985)
  22. 10.1128/MCB.5.10.2753 / Mol. Cell. Biol. / Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60c-src relative to pp60v-src by Coussens (1985)
  23. {'key': '10.1016/0092-8674(93)90641-3_BIB23', 'first-page': '134', 'article-title': 'The development of normal and homozygous Brachyury (TT) mouse embryos in the extraembryonic coelom of the chick', 'volume': '30', 'author': 'Gluecksohn-Schoenheimer', 'year': '1944'} / The development of normal and homozygous Brachyury (TT) mouse embryos in the extraembryonic coelom of the chick by Gluecksohn-Schoenheimer (1944)
  24. 10.1126/science.1361685 / Science / Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice by Grant (1992)
  25. {'key': '10.1016/0092-8674(93)90641-3_BIB25', 'first-page': '124', 'article-title': "Genetical studies on the skeleton of the mouse. XXII. The development of Danforth's short-tail", 'volume': '6', 'author': 'Grüneberg', 'year': '1958', 'journal-title': 'J. Embryol. Exp. Morphol.'} / J. Embryol. Exp. Morphol. / Genetical studies on the skeleton of the mouse. XXII. The development of Danforth's short-tail by Grüneberg (1958)
  26. {'key': '10.1016/0092-8674(93)90641-3_BIB26', 'first-page': '424', 'article-title': 'Genetical studies on the skeleton of the mouse. XXIII. The development of Brachyury and Anury', 'volume': '6', 'author': 'Grüneberg', 'year': '1958', 'journal-title': 'J. Embryol. Exp. Morphol.'} / J. Embryol. Exp. Morphol. / Genetical studies on the skeleton of the mouse. XXIII. The development of Brachyury and Anury by Grüneberg (1958)
  27. 10.1038/350243a0 / Nature / Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells by Hasty (1991)
  28. 10.1016/0092-8674(87)90745-8 / Cell / A tail of two src's: mutasis mutandis by Hunter (1987)
  29. 10.1128/MCB.5.5.1058 / Mol. Cell. Biol. / Low level of cellular protein phosphorylation by nontransforming overproduced p60c-src by Iba (1985)
  30. {'key': '10.1016/0092-8674(93)90641-3_BIB30', 'first-page': '1066', 'article-title': 'Protooncogene expression identifies a transient columnar organization of the forebrain within the late embryonic ventricular zone', 'volume': '86', 'author': 'Johnston', 'year': '1989'} / Protooncogene expression identifies a transient columnar organization of the forebrain within the late embryonic ventricular zone by Johnston (1989)
  31. {'year': '1992', 'series-title': 'The Atlas of Mouse Development', 'author': 'Kaufman', 'key': '10.1016/0092-8674(93)90641-3_BIB31'} / The Atlas of Mouse Development by Kaufman (1992)
  32. 10.1016/0092-8674(87)90756-2 / Cell / Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation by Kmiecik (1987)
  33. 10.1126/science.1708916 / Science / SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins by Koch (1991)
  34. {'key': '10.1016/0092-8674(93)90641-3_BIB34', 'first-page': '4455', 'article-title': 'Characterization of avian and viral p60src proteins expressed in yeast', 'volume': '84', 'author': 'Kornbluth', 'year': '1987'} / Characterization of avian and viral p60src proteins expressed in yeast by Kornbluth (1987)
  35. 10.1016/0092-8674(91)90226-O / Cell / Motorizing the spinal cord by Lumsden (1991)
  36. 10.1128/MCB.9.6.2648 / Mol. Cell. Biol. / Structural differences between repressed and depressed forms of p60c-src by MacAuley (1989)
  37. {'key': '10.1016/0092-8674(93)90641-3_BIB37', 'first-page': '117', 'article-title': 'Phosphorylation of Src mutants at Tyr 527 in fibroblasts does not correlate with in vitro phosphorylation by CSK', 'volume': '8', 'author': 'MacAuley', 'year': '1993', 'journal-title': 'Oncogene'} / Oncogene / Phosphorylation of Src mutants at Tyr 527 in fibroblasts does not correlate with in vitro phosphorylation by CSK by MacAuley (1993)
  38. 10.1126/science.1978757 / Science / Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms by Malkin (1990)
  39. 10.1016/0012-1606(86)90350-7 / Dev. Biol. / An early developmental phase of pp60c-src expression in the neural ectoderm by Maness (1986)
  40. 10.1016/S0021-9258(18)55197-8 / J. Biol. Chem. / Peptides reproducing the phosphoacceptor sites of pp60c-src as substrates for TPK-IIB, a splenic tyrosine kinase devoid of autophosphorylation activity by Marin (1991)
  41. 10.1126/science.1694307 / Science / Binding of transforming protein, p47gag-crk, to a broad range of phosphotyrosine-containing proteins by Matsuda (1990)
  42. 10.1016/0092-8674(90)90385-R / Cell / The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain by McMahon (1990)
  43. 10.1038/351069a0 / Nature / Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src by Nada (1991)
  44. 10.1126/science.1900642 / Science / Recombinase-mediated gene activation and site-specific integration in mammalian cells by O'Gorman (1991)
  45. 10.1016/S0021-9258(18)54220-4 / J. Biol. Chem. / CSK: a protein-tyrosine kinase involved in regulation of src family kinases by Okada (1991)
  46. {'key': '10.1016/0092-8674(93)90641-3_BIB46', 'first-page': '6861', 'article-title': 'Tissue- and site-specific DNA recombination in transgenic mice', 'volume': '89', 'author': 'Orban', 'year': '1992'} / Tissue- and site-specific DNA recombination in transgenic mice by Orban (1992)
  47. {'key': '10.1016/0092-8674(93)90641-3_BIB47', 'first-page': '2013', 'article-title': 'cyl encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src)', 'volume': '6', 'author': 'Partanen', 'year': '1991', 'journal-title': 'Oncogene'} / Oncogene / cyl encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src) by Partanen (1991)
  48. 10.1016/0092-8674(87)90757-4 / Cell / Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src by Piwnica-Worms (1987)
  49. {'key': '10.1016/0092-8674(93)90641-3_BIB49', 'first-page': '9831', 'article-title': 'Brain-specific src oncogene mRNA mapped in rat brain by in situ hybridization', 'volume': '85', 'author': 'Ross', 'year': '1988'} / Brain-specific src oncogene mRNA mapped in rat brain by in situ hybridization by Ross (1988)
  50. {'key': '10.1016/0092-8674(93)90641-3_BIB50', 'first-page': '10696', 'article-title': 'Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src', 'volume': '88', 'author': 'Roussel', 'year': '1991'} / Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src by Roussel (1991)
  51. 10.1128/MCB.8.6.2465 / Mol. Cell. Biol. / Investigation of factors that influence phosphorylation of pp60c-src on tyrosine 527 by Schuh (1988)
  52. 10.1016/0955-0674(91)90062-4 / Curr. Opin. Cell Biol. / Protein tyrosine phosphorylation and the adhesive functions of platelets by Shattil (1991)
  53. 10.1126/science.3024318 / Science / Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses by Soriano (1986)
  54. 10.1016/0092-8674(91)90499-O / Cell / Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice by Soriano (1991)
  55. 10.1016/0092-8674(92)90308-Y / Cell / pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells by Stein (1992)
  56. 10.1016/0092-8674(83)90073-9 / Cell / Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus by Takeya (1983)
  57. {'key': '10.1016/0092-8674(93)90641-3_BIB57', 'first-page': '5128', 'article-title': 'Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs', 'volume': '89', 'author': 'te Riele', 'year': '1992'} / Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs by te Riele (1992)
  58. 10.1126/science.1719633 / Science / Phosphorylation of c-src on tyrosine 527 by another protein kinase by Thomas (1991)
  59. 10.1038/358646a0 / Nature / Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptide by Waksman (1992)
  60. 10.1128/MCB.8.1.502 / Mol. Cell. Biol. / Developmental expression of two forms of pp60c-src in mouse brain by Wiestler (1988)
  61. 10.1128/MCB.11.10.5113 / Mol. Cell. Biol. / Identification and characterization of a novel cytoskeleton-associated pp60src substrate by Wu (1991)
  62. 10.1016/0092-8674(91)90247-V / Cell / Control of cell pattern in the developing nervous system: polarizing activity of the floor plate and notochord by Yamada (1991)
Dates
Type When
Created 20 years, 11 months ago (Aug. 27, 2004, 2:36 p.m.)
Deposited 4 years, 2 months ago (June 25, 2021, 3:07 a.m.)
Indexed 1 month ago (July 19, 2025, 11:51 p.m.)
Issued 32 years, 2 months ago (June 1, 1993)
Published 32 years, 2 months ago (June 1, 1993)
Published Print 32 years, 2 months ago (June 1, 1993)
Funders 0

None

@article{Imamoto_1993, title={Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice}, volume={73}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/0092-8674(93)90641-3}, DOI={10.1016/0092-8674(93)90641-3}, number={6}, journal={Cell}, publisher={Elsevier BV}, author={Imamoto, Akira and Soriano, Philippe}, year={1993}, month=jun, pages={1117–1124} }