Crossref journal-article
Elsevier BV
Cell (78)
Bibliography

Ridley, A. J., Paterson, H. F., Johnston, C. L., Diekmann, D., & Hall, A. (1992). The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell, 70(3), 401–410.

Authors 5
  1. Anne J. Ridley (first)
  2. Hugh F. Paterson (additional)
  3. Caroline L. Johnston (additional)
  4. Dagmar Diekmann (additional)
  5. Alan Hall (additional)
References 45 Referenced 2,994
  1. 10.1038/353668a0 / Nature / The small GTP-binding protein, p21rac1, is involved in the activation of the phagocyte NADPH oxidase by Abo (1991)
  2. 10.1083/jcb.111.1.131 / J. Cell Biol. / CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae by Adams (1990)
  3. 10.1126/science.3090687 / Science / Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins by Bar-Sagi (1986)
  4. 10.1002/jcp.1041330414 / J. Cell. Physiol. / Inhibition of cell surface ruffling and fluid-phase pinocytosis by microinjection of anti-ras antibodies into living cells by Bar-Sagi (1987)
  5. {'key': '10.1016/0092-8674(92)90164-8_BIB5', 'first-page': '395', 'article-title': 'Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells', 'volume': '88', 'author': 'Battey', 'year': '1991'} / Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells by Battey (1991)
  6. 10.1038/349117a0 / Nature / The GTPase superfamily: conserved structure and molecular mechanism by Bourne (1991)
  7. 10.1128/MCB.10.10.5314 / Mol. Cell. Biol. / Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells by Cai (1990)
  8. 10.1083/jcb.115.3.677 / J. Cell Biol. / Kinetic analysis of F-actin depolymerisation in polymorphonuclear leukocyte lysates indicates that chemoattractant stimulation increases actin filament number without altering the filament length distribution by Cano (1991)
  9. 10.1083/jcb.103.6.2707 / J. Cell Biol. / An actin-nucleating activity in polymorphonuclear leukocytes is modulated by chemotactic peptides by Carson (1986)
  10. 10.1002/j.1460-2075.1989.tb03477.x / EMBO J. / The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells by Chardin (1989)
  11. 10.1016/0092-8674(91)90638-F / Cell / Growth factors in development, transformation, and tumorigenesis by Cross (1991)
  12. 10.1016/S0021-9258(19)84716-6 / J. Biol. Chem. / Rac, a novel ras-related family of proteins that are botulinum toxin substrates by Didsbury (1989)
  13. 10.1038/351400a0 / Nature / Bcr encodes a GTPase activating protein for p21rac by Diekmann (1991)
  14. 10.1083/jcb.116.3.695 / J. Cell Biol. / Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C by Downey (1992)
  15. 10.1016/0968-0004(90)90300-Z / Trends Biochem. Sci. / The ras superfamily of small GTP-binding proteins by Downward (1990)
  16. 10.1038/346719a0 / Nature / Stimulation of p21ras upon T-cell activation by Downward (1990)
  17. 10.1128/MCB.5.12.3610 / Mol. Cell. Biol. / Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product by Evan (1985)
  18. 10.1128/MCB.11.10.4822 / Mol. Cell. Biol. / Dominant inhibitory mutations in the Mg2+-binding site of RasH prevent its activation by GTP by Farnsworth (1991)
  19. 10.1128/MCB.8.8.3235 / Mol. Cell. Biol. / Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP by Feig (1988)
  20. 10.1128/JVI.43.1.294-304.1982 / J. Virol. / Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and the cellular ras gene family by Furth (1982)
  21. 10.1126/science.2116664 / Science / The cellular function of small GTP-binding proteins by Hall (1990)
  22. 10.1016/S0021-9258(18)67333-8 / J. Biol. Chem. / The effect of Mg2+ on the guanine nucleotide exchange rate of p21N-ras by Hall (1986)
  23. 10.1016/0006-291X(92)91820-G / Biochem. Biophys. Res. Commun. / Both stimulatory and inhibitory GDPGTP exchange proteins, smgGDS and rhoGDI, are active on multiple small GTP-binding proteins by Hiraoka (1992)
  24. 10.1083/jcb.111.1.143 / J. Cell Biol. / Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity by Johnson (1990)
  25. 10.1002/jcp.1041450311 / J. Cell. Physiol. / Diacylglycerols and PMA are particularly effective stimulators of fluid pinocytosis in human neutrophils by Keller (1990)
  26. 10.1242/jcs.96.1.99 / J. Cell Sci. / The protein kinase C inhibitor H-7 activates human neutrophils: effect on shape, actin polymerization, fluid pinocytosis and locomotion by Keller (1990)
  27. 10.1126/science.1660188 / Science / Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac2 by Knaus (1991)
  28. 10.1002/j.1460-2075.1989.tb03479.x / EMBO J / p21H-ras-induced morphological transformation and increases in c-myc expression are independent of functional protein kinase C by Lloyd (1989)
  29. 10.1128/MCB.11.12.5963 / Mol. Cell. Biol. / Two dominant inhibitory mutants of p21ras interfere with insulin-induced gene expression by Medema (1991)
  30. 10.1084/jem.164.5.1478 / J. Exp. Med. / Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain by Miller (1986)
  31. {'key': '10.1016/0092-8674(92)90164-8_BIB31', 'first-page': '863', 'article-title': 'The murine rac1 gene: cDNA cloning, tissue distribution and regulated expression of rac1 mRNA by disassembly of actin microfilaments', 'volume': '6', 'author': 'Moll', 'year': '1991', 'journal-title': 'Oncogene'} / Oncogene / The murine rac1 gene: cDNA cloning, tissue distribution and regulated expression of rac1 mRNA by disassembly of actin microfilaments by Moll (1991)
  32. 10.1111/j.1432-1033.1991.tb16312.x / Eur. J. Biochem. / The superoxide-generating oxidase of phagocytic cells by Morel (1991)
  33. 10.1038/313241a0 / Nature / Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells by Mulcahy (1985)
  34. 10.1152/physrev.1987.67.1.285 / Physiol. Rev. / Signal transduction and cytoskeletal activation in the neutrophil by Omann (1987)
  35. 10.1083/jcb.111.3.1001 / J. Cell Biol. / Microinjection of recombinant p21rho induces rapid changes in cell morphology by Paterson (1990)
  36. 10.1016/0092-8674(92)90163-7 / Cell / The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors by Ridley (1992)
  37. 10.1093/oxfordjournals.bmb.a072339 / British Med. Bull. / Signal transduction pathways in mitogenesis by Rozengurt (1989)
  38. 10.1016/S0021-9258(18)81834-8 / J. Biol. Chem. / Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase by Sekine (1989)
  39. {'key': '10.1016/0092-8674(92)90164-8_BIB39', 'first-page': '769', 'article-title': 'A member of the ras gene superfamily is specifically expressed in T, B and myeloid hemopoietic cells', 'volume': '5', 'author': 'Shirsat', 'year': '1990', 'journal-title': 'Oncogene'} / Oncogene / A member of the ras gene superfamily is specifically expressed in T, B and myeloid hemopoietic cells by Shirsat (1990)
  40. 10.1016/0378-1119(88)90005-4 / Gene / Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase by Smith (1988)
  41. {'key': '10.1016/0092-8674(92)90164-8_BIB41', 'first-page': '482', 'article-title': 'Tumor promoter induces reorganization of actin filaments and calspectin (fodrin or nonerythroid spectrin) in 3T3 cells', 'volume': '85', 'author': 'Sobue', 'year': '1988'} / Tumor promoter induces reorganization of actin filaments and calspectin (fodrin or nonerythroid spectrin) in 3T3 cells by Sobue (1988)
  42. 10.1128/MCB.11.8.4053 / Mol. Cell. Biol. / Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras by Stacey (1991)
  43. {'key': '10.1016/0092-8674(92)90164-8_BIB43', 'first-page': '2297', 'article-title': 'Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes', 'volume': '6', 'author': 'Stacey', 'year': '1991', 'journal-title': 'Oncogene'} / Oncogene / Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes by Stacey (1991)
  44. 10.1016/0092-8674(89)90868-4 / Cell / Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins by van Corven (1989)
  45. 10.1016/0092-8674(88)90531-4 / Cell / Cellular ras activity and phospholipid metabolism by Yu (1988)
Dates
Type When
Created 21 years, 3 months ago (May 1, 2004, 5:50 a.m.)
Deposited 4 years, 2 months ago (June 17, 2021, 2:03 a.m.)
Indexed 15 hours, 31 minutes ago (Aug. 24, 2025, 6:54 p.m.)
Issued 33 years ago (Aug. 1, 1992)
Published 33 years ago (Aug. 1, 1992)
Published Print 33 years ago (Aug. 1, 1992)
Funders 0

None

@article{Ridley_1992, title={The small GTP-binding protein rac regulates growth factor-induced membrane ruffling}, volume={70}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/0092-8674(92)90164-8}, DOI={10.1016/0092-8674(92)90164-8}, number={3}, journal={Cell}, publisher={Elsevier BV}, author={Ridley, Anne J. and Paterson, Hugh F. and Johnston, Caroline L. and Diekmann, Dagmar and Hall, Alan}, year={1992}, month=aug, pages={401–410} }