DOI: 10.1016/0092-8674(88)90134-1. A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein β subunit

A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein β subunit

10.1016/0092-8674(88)90134-1

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Hartley, D. A., Preiss, A., & Artavanis-Tsakonas, S. (1988). A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein Î² subunit. Cell, 55(5), 785â795.

Authors 3

David A. Hartley (first)
Anette Preiss (additional)
Spyros Artavanis-Tsakonas (additional)

References 56 Referenced 152

10.1016/0168-9525(88)90096-0 / Trends Genet. / The molecular biology of the Notch locus and the fine tuning of differentiation in Drosophila by Artavanis-Tsakonas (1988)
{'key': '10.1016/0092-8674(88)90134-1_BIB2', 'first-page': '5561', 'article-title': 'Clones from the human gene complex coding for salivary proline-rich proteins', 'volume': '81', 'author': 'Azen', 'year': '1984'} / Clones from the human gene complex coding for salivary proline-rich proteins by Azen (1984)
{'key': '10.1016/0092-8674(88)90134-1_BIB3', 'first-page': '317', 'article-title': 'Embryogenesis of an insect nervous system. I. A map of the thoracic and abdominal neuroblasts in Locusta migratoria', 'volume': '61', 'author': 'Bate', 'year': '1976', 'journal-title': 'J. Embryol. Exp. Morphol.'} / J. Embryol. Exp. Morphol. / Embryogenesis of an insect nervous system. I. A map of the thoracic and abdominal neuroblasts in Locusta migratoria by Bate (1976)
10.1126/science.322279 / Science / Screening lambda gt10 recombinant clones by hybridizing to single plaques in situ by Benton (1977)
10.1038/321814a0 / Nature / One molecular mechanism can transduce diverse signals by Bourne (1986)
10.1038/329651a0 / Nature / Similarity between cell cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila by Breeden (1987)
10.1016/0022-2836(88)90010-1 / J. Mol. Biol. / Functional cDNA libraries from Drosophila embryos by Brown (1988)
{'key': '10.1016/0092-8674(88)90134-1_BIB8', 'series-title': 'The embryonic development of Drosophila melanogaster', 'author': 'Campos-Ortega', 'year': '1985'} / The embryonic development of Drosophila melanogaster by Campos-Ortega (1985)
10.1093/nar/15.4.1353 / Nucl. Acids Res. / Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates by Cavener (1987)
10.1126/science.2436299 / Science / The alpha subunit of the GTP binding protein Gk opens atrial potassium channels by Codina (1987)
10.1016/0147-619X(85)90053-8 / Plasmid / A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: application to sequencing the corn mitochondrial 18S rDNA by Dale (1985)
10.1093/genetics/118.3.499 / Genetics / Functional interactions of neurogenic genes of Drosophila melanogaster by de la Concha (1988)
10.3109/01677068409107094 / J. Neurogenet / The expression of neurogenic loci in imaginal epidermal cells of Drosophila melanogaster by Dietrich (1984)
10.1016/0012-1606(85)90445-2 / Dev. Biol. / Early events in insect neurogenesis. I. Development and segmental differences in the pattern of neuronal precursor cells by Doe (1985)
10.1016/0012-1606(85)90446-4 / Dev. Biol. / Early events in insect neurogenesis. II. The role of cell interactions and cell lineage in the determination of neuronal precursor cells by Doe (1985)
10.1126/science.7355290 / Science / Collagen: molecular diversity in the body's protein scaffold by Eyre (1980)
10.1016/0003-2697(83)90418-9 / Anal. Biochem. / A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity by Feinberg (1983)
{'key': '10.1016/0092-8674(88)90134-1_BIB18', 'first-page': '2162', 'article-title': 'Repetitive segmental structure of the transducin β subunit: homology with the CDC4 gene and identification of related mRNAs', 'volume': '83', 'author': 'Fong', 'year': '1986'} / Repetitive segmental structure of the transducin β subunit: homology with the CDC4 gene and identification of related mRNAs by Fong (1986)
{'key': '10.1016/0092-8674(88)90134-1_BIB19', 'first-page': '3792', 'article-title': 'Distinct forms of the β subunit of GTP-binding regulatory proteins identified by molecular cloning', 'volume': '84', 'author': 'Fong', 'year': '1987'} / Distinct forms of the β subunit of GTP-binding regulatory proteins identified by molecular cloning by Fong (1987)
{'key': '10.1016/0092-8674(88)90134-1_BIB20', 'first-page': '6122', 'article-title': 'A second form of the β subunit of signal-transducing G proteins', 'volume': '84', 'author': 'Gao', 'year': '1987'} / A second form of the β subunit of signal-transducing G proteins by Gao (1987)
10.1146/annurev.bi.56.070187.003151 / Annu. Rev. Biochem. / G proteins: transducers of receptor-generated signals by Gilman (1987)
10.1093/nar/12.1Part2.539 / Nucl. Acids Res. / The codon preference plot: graphic analysis of protein coding sequences and prediction of gene expression by Gribshov (1984)
10.1007/BF00848159 / Roux's Arch. Dev. Biol. / Early neurogenesis in wild-type Drosophila melanogaster by Hartenstein (1984)
10.1002/j.1460-2075.1987.tb02664.x / EMBO J. / The embryonic expression of the Notch locus of Drosophila melanogaster and the implications of point mutations in the extracellular EGF-like domain of the predicted protein by Hartley (1987)
10.1016/0378-1119(84)90153-7 / Gene / Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing by Henikoff (1984)
10.1016/0092-8674(86)90353-3 / Cell / Local function of the Notch gene for embryonic ectodermal pathway choice in Drosophila by Hoppe (1986)
10.1038/318439a0 / Nature / Transcription pattern of the Drosophila segmentation gene hairy by Ingham (1985)
{'key': '10.1016/0092-8674(88)90134-1_BIB28', 'first-page': '3623', 'article-title': 'Stimulation of phospholipase A2 activity in bovine rod outer segments by the βgamma subunits of transducin and its inhibition by the α subunit', 'volume': '84', 'author': 'Jelsema', 'year': '1987'} / Stimulation of phospholipase A2 activity in bovine rod outer segments by the βgamma subunits of transducin and its inhibition by the α subunit by Jelsema (1987)
10.1016/0092-8674(87)90123-1 / Cell / Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus by Kelley (1987)
10.1016/0012-1606(87)90351-4 / Dev. Biol. / The Enhancer of split locus and neurogenesis in Drosophila melanogaster by Knust (1987)
10.1002/j.1460-2075.1987.tb02757.x / EMBO J. / Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster by Knust (1987)
10.1016/0022-2836(82)90515-0 / J. Mol. Biol. / A simple method for displaying the hydropathic character of a protein by Kyte (1982)
10.1007/BF00848482 / Roux's Arch. Dev. Biol. / On the phenotype and development of mutants of early neurogenesis in Drosophila melanogaster by Lehmann (1983)
10.1126/science.2983426 / Science / Rapid and sensitive protein similarity searches by Lipman (1985)
10.1038/325321a0 / Nature / The βgamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart by Logothetis (1987)
{'key': '10.1016/0092-8674(88)90134-1_BIB36', 'first-page': '7665', 'article-title': 'Enhanced graphic matrix analysis of nucleic acid protein sequences', 'volume': '78', 'author': 'Maizel', 'year': '1981'} / Enhanced graphic matrix analysis of nucleic acid protein sequences by Maizel (1981)
{'key': '10.1016/0092-8674(88)90134-1_BIB37', 'series-title': 'Ph.D. thesis', 'article-title': 'The role of the Notch locus in the imaginal development of Drosophila melanogaster', 'author': 'Markopoulou', 'year': '1987'} / Ph.D. thesis / The role of the Notch locus in the imaginal development of Drosophila melanogaster by Markopoulou (1987)
10.1093/nar/14.3.1319 / Nucl. Acids Res. / Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7 deazaguanosine triphosphate in place of dGTP by Mizusawa (1986)
10.1016/0022-2836(70)90057-4 / J. Mol. Biol. / A general method applicable to the search for similarities in the amino acid sequence of two proteins by Needleman (1970)
10.1016/0092-8674(85)90306-X / Cell / The engrailed locus of Drosophila: structural analysis of an embryonic transcript by Poole (1985)
{'key': '10.1016/0092-8674(88)90134-1_BIB41', 'first-page': '133', 'article-title': 'Chromosomal deficiencies and embryonic development of Drosophila melanogaster', 'volume': '23', 'author': 'Poulson', 'year': '1937'} / Chromosomal deficiencies and embryonic development of Drosophila melanogaster by Poulson (1937)
{'key': '10.1016/0092-8674(88)90134-1_BIB42', 'series-title': 'Biology of Drosophila', 'first-page': '168', 'article-title': 'Histogenesis, organogenesis, and differentiation in the embryo of Drosophila melanogaster', 'author': 'Poulson', 'year': '1950'} / Biology of Drosophila / Histogenesis, organogenesis, and differentiation in the embryo of Drosophila melanogaster by Poulson (1950)
10.1002/j.1460-2075.1988.tb03278.x / EMBO J. / The molecular genetics of enhancer of split, a gene required for embryonic neural development in Drosophila by Preiss (1988)
{'key': '10.1016/0092-8674(88)90134-1_BIB44', 'first-page': '5463', 'article-title': 'DNA sequencing with chain-terminating inhibitors', 'volume': '74', 'author': 'Sanger', 'year': '1977'} / DNA sequencing with chain-terminating inhibitors by Sanger (1977)
10.1146/annurev.cb.02.110186.002135 / Annu. Rev. Cell Biol. / G proteins: a family of signal transducers by Stryer (1986)
{'key': '10.1016/0092-8674(88)90134-1_BIB46', 'first-page': '4767', 'article-title': 'DNA sequence analysis with a modified bacteriophage T7 DNA polymerase', 'volume': '84', 'author': 'Tabor', 'year': '1987'} / DNA sequence analysis with a modified bacteriophage T7 DNA polymerase by Tabor (1987)
10.1007/BF00375748 / Roux's Arch. Dev. Biol. / Lineage analysis of transplanted individual cells in embryos of Drosophila melanogaster II. Commitment and proliferative abilities of epidermal and neural cell precursors by Technau (1986)
{'key': '10.1016/0092-8674(88)90134-1_BIB48', 'first-page': '4500', 'article-title': 'Cell autonomy of expression of neurogenic genes of Drosophila melanogaster', 'volume': '84', 'author': 'Technau', 'year': '1987'} / Cell autonomy of expression of neurogenic genes of Drosophila melanogaster by Technau (1987)
10.1038/310203a0 / Nature / From grasshopper to Drosophila: a common plan for neuronal development by Thomas (1984)
10.3109/01677068509102325 / J. Neurogenet. / Genetic interactions in early neurogenesis of Drosophila melanogaster by Vässin (1985)
10.1002/j.1460-2075.1987.tb02666.x / EMBO J. / The neurogenic locus Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats by Vässin (1987)
{'key': '10.1016/0092-8674(88)90134-1_BIB52', 'first-page': '157', 'article-title': 'Dosage experiments with split mutants in the presence of an enhancer of split', 'volume': '30', 'author': 'Welshons', 'year': '1956', 'journal-title': 'Dros. Inf. Service'} / Dros. Inf. Service / Dosage experiments with split mutants in the presence of an enhancer of split by Welshons (1956)
10.1126/science.150.3700.1122 / Science / Analysis of a gene in Drosophila by Welshons (1965)
10.1016/0092-8674(85)90229-6 / Cell / Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats by Wharton (1985)
{'key': '10.1016/0092-8674(88)90134-1_BIB55', 'article-title': 'Cloning of a Drosophila melanogaster G protein β subunit gene and characterization of its expression during development', 'author': 'Yarfitz', 'year': '1988'} / Cloning of a Drosophila melanogaster G protein β subunit gene and characterization of its expression during development by Yarfitz (1988)
10.1016/0022-2836(87)90646-2 / J. Mol. Biol. / Structural comparison of the yeast cell division cycle gene CDC4 and a related pseudogene by Yochem (1987)

Dates

Type	When
Created	21 years, 4 months ago (May 4, 2004, 6:14 a.m.)
Deposited	4 years, 2 months ago (June 17, 2021, 4:12 a.m.)
Indexed	1 month, 1 week ago (July 27, 2025, 3:28 a.m.)
Issued	36 years, 9 months ago (Dec. 1, 1988)
Published	36 years, 9 months ago (Dec. 1, 1988)
Published Print	36 years, 9 months ago (Dec. 1, 1988)

Funders 0

None

BibTeX

@article{Hartley_1988, title={A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein β subunit}, volume={55}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/0092-8674(88)90134-1}, DOI={10.1016/0092-8674(88)90134-1}, number={5}, journal={Cell}, publisher={Elsevier BV}, author={Hartley, David A. and Preiss, Anette and Artavanis-Tsakonas, Spyros}, year={1988}, month=dec, pages={785–795} }

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      "first-page": "351",
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      "article-title": "Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing",
      "volume": "28",
      "author": "Henikoff",
      "year": "1984",
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      "article-title": "Local function of the Notch gene for embryonic ectodermal pathway choice in Drosophila",
      "volume": "46",
      "author": "Hoppe",
      "year": "1986",
      "journal-title": "Cell"
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      "first-page": "439",
      "DOI": "10.1038/318439a0",
      "article-title": "Transcription pattern of the Drosophila segmentation gene hairy",
      "volume": "318",
      "author": "Ingham",
      "year": "1985",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0092-8674(88)90134-1_BIB28",
      "first-page": "3623",
      "article-title": "Stimulation of phospholipase A2 activity in bovine rod outer segments by the \u03b2gamma subunits of transducin and its inhibition by the \u03b1 subunit",
      "volume": "84",
      "author": "Jelsema",
      "year": "1987"
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      "first-page": "539",
      "DOI": "10.1016/0092-8674(87)90123-1",
      "article-title": "Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus",
      "volume": "51",
      "author": "Kelley",
      "year": "1987",
      "journal-title": "Cell"
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "262",
      "DOI": "10.1016/0012-1606(87)90351-4",
      "article-title": "The Enhancer of split locus and neurogenesis in Drosophila melanogaster",
      "volume": "122",
      "author": "Knust",
      "year": "1987",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1016/0092-8674(88)90134-1_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "4113",
      "DOI": "10.1002/j.1460-2075.1987.tb02757.x",
      "article-title": "Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster",
      "volume": "6",
      "author": "Knust",
      "year": "1987",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/0092-8674(88)90134-1_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "105",
      "DOI": "10.1016/0022-2836(82)90515-0",
      "article-title": "A simple method for displaying the hydropathic character of a protein",
      "volume": "157",
      "author": "Kyte",
      "year": "1982",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/0092-8674(88)90134-1_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "62",
      "DOI": "10.1007/BF00848482",
      "article-title": "On the phenotype and development of mutants of early neurogenesis in Drosophila melanogaster",
      "volume": "192",
      "author": "Lehmann",
      "year": "1983",
      "journal-title": "Roux's Arch. Dev. Biol."
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    {
      "key": "10.1016/0092-8674(88)90134-1_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "1435",
      "DOI": "10.1126/science.2983426",
      "article-title": "Rapid and sensitive protein similarity searches",
      "volume": "227",
      "author": "Lipman",
      "year": "1985",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0092-8674(88)90134-1_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "321",
      "DOI": "10.1038/325321a0",
      "article-title": "The \u03b2gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart",
      "volume": "325",
      "author": "Logothetis",
      "year": "1987",
      "journal-title": "Nature"
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    {
      "key": "10.1016/0092-8674(88)90134-1_BIB36",
      "first-page": "7665",
      "article-title": "Enhanced graphic matrix analysis of nucleic acid protein sequences",
      "volume": "78",
      "author": "Maizel",
      "year": "1981"
    },
    {
      "key": "10.1016/0092-8674(88)90134-1_BIB37",
      "series-title": "Ph.D. thesis",
      "article-title": "The role of the Notch locus in the imaginal development of Drosophila melanogaster",
      "author": "Markopoulou",
      "year": "1987"
    },
    {
      "key": "10.1016/0092-8674(88)90134-1_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "1319",
      "DOI": "10.1093/nar/14.3.1319",
      "article-title": "Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7 deazaguanosine triphosphate in place of dGTP",
      "volume": "14",
      "author": "Mizusawa",
      "year": "1986",
      "journal-title": "Nucl. Acids Res."
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      "first-page": "443",
      "DOI": "10.1016/0022-2836(70)90057-4",
      "article-title": "A general method applicable to the search for similarities in the amino acid sequence of two proteins",
      "volume": "48",
      "author": "Needleman",
      "year": "1970",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/0092-8674(88)90134-1_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "37",
      "DOI": "10.1016/0092-8674(85)90306-X",
      "article-title": "The engrailed locus of Drosophila: structural analysis of an embryonic transcript",
      "volume": "40",
      "author": "Poole",
      "year": "1985",
      "journal-title": "Cell"
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    {
      "key": "10.1016/0092-8674(88)90134-1_BIB41",
      "first-page": "133",
      "article-title": "Chromosomal deficiencies and embryonic development of Drosophila melanogaster",
      "volume": "23",
      "author": "Poulson",
      "year": "1937"
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    {
      "key": "10.1016/0092-8674(88)90134-1_BIB42",
      "series-title": "Biology of Drosophila",
      "first-page": "168",
      "article-title": "Histogenesis, organogenesis, and differentiation in the embryo of Drosophila melanogaster",
      "author": "Poulson",
      "year": "1950"
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    {
      "key": "10.1016/0092-8674(88)90134-1_BIB43",
      "doi-asserted-by": "crossref",
      "DOI": "10.1002/j.1460-2075.1988.tb03278.x",
      "article-title": "The molecular genetics of enhancer of split, a gene required for embryonic neural development in Drosophila",
      "volume": "7",
      "author": "Preiss",
      "year": "1988",
      "journal-title": "EMBO J."
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    {
      "key": "10.1016/0092-8674(88)90134-1_BIB44",
      "first-page": "5463",
      "article-title": "DNA sequencing with chain-terminating inhibitors",
      "volume": "74",
      "author": "Sanger",
      "year": "1977"
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      "key": "10.1016/0092-8674(88)90134-1_BIB45",
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      "first-page": "391",
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      "article-title": "G proteins: a family of signal transducers",
      "volume": "2",
      "author": "Stryer",
      "year": "1986",
      "journal-title": "Annu. Rev. Cell Biol."
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    {
      "key": "10.1016/0092-8674(88)90134-1_BIB46",
      "first-page": "4767",
      "article-title": "DNA sequence analysis with a modified bacteriophage T7 DNA polymerase",
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      "author": "Tabor",
      "year": "1987"
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      "DOI": "10.1007/BF00375748",
      "article-title": "Lineage analysis of transplanted individual cells in embryos of Drosophila melanogaster II. Commitment and proliferative abilities of epidermal and neural cell precursors",
      "volume": "195",
      "author": "Technau",
      "year": "1986",
      "journal-title": "Roux's Arch. Dev. Biol."
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      "first-page": "4500",
      "article-title": "Cell autonomy of expression of neurogenic genes of Drosophila melanogaster",
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      "DOI": "10.1038/310203a0",
      "article-title": "From grasshopper to Drosophila: a common plan for neuronal development",
      "volume": "310",
      "author": "Thomas",
      "year": "1984",
      "journal-title": "Nature"
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      "DOI": "10.3109/01677068509102325",
      "article-title": "Genetic interactions in early neurogenesis of Drosophila melanogaster",
      "volume": "2",
      "author": "V\u00e4ssin",
      "year": "1985",
      "journal-title": "J. Neurogenet."
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      "first-page": "3431",
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      "volume": "11",
      "author": "V\u00e4ssin",
      "year": "1987",
      "journal-title": "EMBO J."
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      "first-page": "157",
      "article-title": "Dosage experiments with split mutants in the presence of an enhancer of split",
      "volume": "30",
      "author": "Welshons",
      "year": "1956",
      "journal-title": "Dros. Inf. Service"
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      "year": "1965",
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      "volume": "43",
      "author": "Wharton",
      "year": "1985",
      "journal-title": "Cell"
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      "article-title": "Cloning of a Drosophila melanogaster G protein \u03b2 subunit gene and characterization of its expression during development",
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      "volume": "195",
      "author": "Yochem",
      "year": "1987",
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