DOI: 10.1016/0090-6980(77)90306-9. Thromboxane synthetase inhibitors as pharmacological tools: Differential biochemical and biological effects on platelet suspensions

Thromboxane synthetase inhibitors as pharmacological tools: Differential biochemical and biological effects on platelet suspensions

10.1016/0090-6980(77)90306-9

Crossref journal-article

Elsevier BV

Prostaglandins (78)

Bibliography

Needleman, P., Bryan, B., Wyche, A., Bronson, S. D., Eakins, K., Ferrendelli, J. A., & Minkes, M. (1977). Thromboxane synthetase inhibitors as pharmacological tools: Differential biochemical and biological effects on platelet suspensions. Prostaglandins, 14(5), 897â907.

Authors 7

Philip Needleman (first)
Bruce Bryan (additional)
Angela Wyche (additional)
Sue D. Bronson (additional)
Ken Eakins (additional)
James A. Ferrendelli (additional)
Mark Minkes (additional)

References 25 Referenced 42

10.1038/261558a0 / Nature / Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides by Needleman (1976)
10.1016/0090-6980(76)90014-9 / Prostaglandins / Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition by Moncada (1976)
{'key': '10.1016/0090-6980(77)90306-9_BIB3', 'first-page': '1716', 'article-title': 'Application of imidazole as a selective inhibitor of thromboxane synthetase in human platelets', 'volume': '74', 'author': 'Needleman', 'year': '1977'} / Application of imidazole as a selective inhibitor of thromboxane synthetase in human platelets by Needleman (1977)
10.1016/0090-6980(77)90232-5 / Prostaglandins / Imidazole: A selective potent antagonist of thromboxane synthetase by Moncada (1977)
10.1016/0090-6980(76)90027-7 / Prostaglandins / N-0164 inhibits generation of thromboxane A2-like activity from prostaglandin endoperoxides by human platelet microsomes by Kulkarni (1976)
10.1111/j.1476-5381.1977.tb16757.x / Brit. J. Pharmacol. / Selective inhibitory actions of sodium-p-benzyl-4-[1-oxo-2(4-chlorobenzyl)-3-phenlpropyl'] phynyl phosphonate (N-0164) and idomethacin on the biosynthesis of prostaglandins and thromboxanes from arachidonic acid by Eakins (1977)
{'key': '10.1016/0090-6980(77)90306-9_BIB7', 'article-title': 'Inhibition of human platelet thromboxane synthetase by 9,11-azoprosta-5, 13-dienoic acid', 'author': 'Gorman', 'year': '1977'} / Inhibition of human platelet thromboxane synthetase by 9,11-azoprosta-5, 13-dienoic acid by Gorman (1977)
10.1016/0006-291X(77)90602-7 / Biochem. Biophys. Res. Comm. / Biosynthesis of thromboxanes in human platelets. I. Characterization and assay of thromboxane synthetase by Sun (1977)
Gryglewski, R. J., A. Zmuda, R. Korbut. Selective inhibition of thromboxane A2 biosynthesis in blood platelets. Nature 267: 627. (10.1038/267627a0)
10.1172/JCI108659 / J. Clin. Invest. / Cyclic adenosine 3′,5′-monophosphate inhibits the availability of arachidonate to prostaglandin synthetase in human platelet suspensions by Minkes (1977)
{'key': '10.1016/0090-6980(77)90306-9_BIB11', 'first-page': '345', 'volume': '71', 'author': 'Hamberg', 'year': '1974'} by Hamberg (1974)
{'key': '10.1016/0090-6980(77)90306-9_BIB12', 'first-page': '207', 'article-title': "Femtole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution", 'volume': '1', 'author': 'Harper', 'year': '1975', 'journal-title': 'J. Cyclic Nucleotide Res.'} / J. Cyclic Nucleotide Res. / Femtole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution by Harper (1975)
10.1016/S0021-9258(19)45621-4 / J. Biol. Chem. / Radioimmunoassay for cyclic nucleotides I. Preparation of antibodies and iodinated cyclic nucleotides by Steiner (1972)
10.1126/science.945611 / Science / Thromboxane: Selective biosynthesis and distinct biological properties by Needleman (1976)
10.1016/0090-6980(77)90132-0 / Prostaglandins / Prostaglandins H1 and H2. Convenient biochemical synthesis and isolation. Further biological and spectroscopic characterization by Gorman (1977)
10.1016/0005-2760(76)90273-3 / Biochem. Biophys. Acta / Isomerization of prostaglandin H2 into prostaglandin D2 in the presence of serum albumin by Hamberg (1976)
10.1111/j.1476-5381.1976.tb07709.x / Brit. J. Pharmacol. / Prostaglandin antagonism by sodium p-Benzyl-4-[1-oxo-2-(4-chlorobenzyl)-3-phenylprophyl] phenyl phosphonate (N-0164) by Eakins (1976)
10.1016/0005-2760(77)90188-6 / Biochem Biophys Acta / Endoperoxides and thromboxane: structural determinants for platelet aggregation and vasoconstriction by Raz (1977)
{'key': '10.1016/0090-6980(77)90306-9_BIB19', 'first-page': '231', 'article-title': 'Role of cyclic AMP in platelet function', 'volume': '1', 'author': 'Salzman', 'year': '1972', 'journal-title': 'Adv. Cyclic Nucleotide Res.'} / Adv. Cyclic Nucleotide Res. / Role of cyclic AMP in platelet function by Salzman (1972)
10.1007/BF02027355 / Agents and Actions / Substances that increase the cyclic AMP content prevent platelet aggregation and the concurrent release of pharmacologically active substances evoked by arachidonic acid by Vargaftig (1975)
{'key': '10.1016/0090-6980(77)90306-9_BIB21', 'first-page': '333', 'article-title': 'Interactions of the pharmacological receptors of blood platelets with adenylate cyclase', 'volume': '6', 'author': 'Haslam', 'year': '1973', 'journal-title': 'Ser. Haematol.'} / Ser. Haematol. / Interactions of the pharmacological receptors of blood platelets with adenylate cyclase by Haslam (1973)
{'key': '10.1016/0090-6980(77)90306-9_BIB22', 'first-page': '79', 'article-title': 'Modulation of platelet cyclic nucleotide content by PGE1 and the prostaglandin endoperoxide PGG2', 'volume': '2', 'author': 'Miller', 'year': '1976', 'journal-title': 'J. Cyclic Nucleotide Res.'} / J. Cyclic Nucleotide Res. / Modulation of platelet cyclic nucleotide content by PGE1 and the prostaglandin endoperoxide PGG2 by Miller (1976)
10.1016/S0021-9258(18)60316-3 / J. Biol. Chem. / Adenosine 3′5′-phosphate in biological materials. I. Purification and properties of cyclic-3′5′-nucleotide phosphodiesterase and use of this enzume to characterize adenosine 3′5′-phosphate in human urine by Butcher (1962)
10.1016/0014-2999(77)90199-6 / Europ. J. Pharmacol. / Action of methylxanthines and imidazole on the contractility of the terminal ileum of the guinea pig by Kazic (1977)
10.1111/j.1748-1716.1976.tb10329.x / Acta Physiol Scand. / Contraction of glycerol extracted fibers of smooth muscle by acetylcholine and imidazole in the presence of a Ca-binding micsomal fraction from rabbit colon by Nilsson (1976)

Dates

Type	When
Created	22 years, 6 months ago (Feb. 12, 2003, 9:04 a.m.)
Deposited	4 years, 3 months ago (June 4, 2021, 9:12 a.m.)
Indexed	2 days, 6 hours ago (Sept. 4, 2025, 10:35 a.m.)
Issued	47 years, 10 months ago (Nov. 1, 1977)
Published	47 years, 10 months ago (Nov. 1, 1977)
Published Print	47 years, 10 months ago (Nov. 1, 1977)

Funders 0

None

BibTeX

@article{Needleman_1977, title={Thromboxane synthetase inhibitors as pharmacological tools: Differential biochemical and biological effects on platelet suspensions}, volume={14}, ISSN={0090-6980}, url={http://dx.doi.org/10.1016/0090-6980(77)90306-9}, DOI={10.1016/0090-6980(77)90306-9}, number={5}, journal={Prostaglandins}, publisher={Elsevier BV}, author={Needleman, Philip and Bryan, Bruce and Wyche, Angela and Bronson, Sue D. and Eakins, Ken and Ferrendelli, James A. and Minkes, Mark}, year={1977}, month=nov, pages={897–907} }

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