DOI: 10.1016/0028-3908(93)90020-4. Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells

Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells

10.1016/0028-3908(93)90020-4

Crossref journal-article

Elsevier BV

Neuropharmacology (78)

Bibliography

Lafon-Cazal, M., Culcasi, M., Gaven, F., Pietri, S., & Bockaert, J. (1993). Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells. Neuropharmacology, 32(11), 1259â1266.

Authors 5

Mireille Lafon-Cazal (first)
Marcel Culcasi (additional)
Florence Gaven (additional)
Sylvia Pietri (additional)
Joël Bockaert (additional)

References 51 Referenced 161

10.1016/0022-510X(92)90191-M / J. Neurol. Sci. / Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex by Beal (1992)
{'key': '10.1016/0028-3908(93)90020-4_BIB2', 'first-page': '1620', 'article-title': 'Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide', 'volume': '87', 'author': 'Beckman', 'year': '1990'} / Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide by Beckman (1990)
{'key': '10.1016/0028-3908(93)90020-4_BIB3', 'first-page': '43', 'article-title': "Les canaux ioniques dans 1'anoxie céré-brale: cibles possibles d'agents protecteurs", 'volume': '7', 'author': 'Ben-Ari', 'year': '1991', 'journal-title': 'Méd. Sci.'} / Méd. Sci. / Les canaux ioniques dans 1'anoxie céré-brale: cibles possibles d'agents protecteurs by Ben-Ari (1991)
10.1016/0896-6273(92)90104-L / Neuron / Nitric oxide, a novel neuronal messenger by Bredt (1992)
10.1038/351714a0 / Nature / Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase by Bredt (1991)
{'key': '10.1016/0028-3908(93)90020-4_BIB6', 'first-page': '444', 'article-title': 'Nitric oxide: an endogenous anticonvulsant substance', 'volume': '4', 'author': 'Buisson', 'year': '1993', 'journal-title': 'Neuro Report'} / Neuro Report / Nitric oxide: an endogenous anticonvulsant substance by Buisson (1993)
10.1016/0891-5849(93)90088-C / Free Rad. Biol. Med. / Superoxide and nitric oxide cooperation in hypoxia/reoxygenation-induced neuron injury by Cazevieille Muller (1993)
10.1007/BF00581130 / Plügers Arch. / Atrial natriuretic peptide effects on cyclic GMP and cyclic AMP contents in microdissected glomeruli and segments of the rat and rabbit nephron by Chabardesse (1987)
10.1016/0166-2236(88)90200-7 / Trends Neurosci. / Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage by Choi (1988)
10.1016/0896-6273(88)90162-6 / Neuron / Glutamate neurotoxicity and disease of the nervous system by Choi (1988)
10.1523/JNEUROSCI.10-08-02493.1990 / J. Neurosci. / Cerebral hypoxia: some new approaches and unanswered questions by Choi (1990)
10.1523/JNEUROSCI.13-06-02651.1993 / J. Neurosci. / Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures by Dawson (1993)
{'key': '10.1016/0028-3908(93)90020-4_BIB13', 'first-page': '6368', 'article-title': 'Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures', 'volume': '88', 'author': 'Dawson', 'year': '1991'} / Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures by Dawson (1991)
10.1016/S0006-291X(05)81441-X / Biochem. Biophys. Res. Commun. / Absence of implication of l-argininenitric oxide pathway on neuronal cell injury induced by l-glutamate or hypoxia by Demerlé-Pellardy (1991)
10.1002/jnr.490270105 / J. Neurosci. Res. / Rapid, sensitive and simple method for the quantification of both neurotoxic and neurotrophic effects of NMDA on cultured cerebellar granule cells by Didier (1990)
10.1111/j.1600-0404.1992.tb08052.x / Acta Neurol. Scand. / Protection against ischemic hippocampal CA1 damage in the rat with a new non-NMDA antagonist, NBQX by Diemer (1992)
10.1016/0165-6147(90)90238-4 / Trends Pharmac. Sci. / Excitatory amino acid receptors in epilepsy by Dingledine (1990)
10.1016/0014-2999(90)90623-E / Eur. J. Pharmac. / Nanomolar NG-nitroarginine inhibits NMDA-induced cyclic GMP formation in rat cerebellum by East (1990)
10.1126/science.2567056 / Science / The role of excitatory amino-acids and NMDA receptors in traumatic brain injury by Faden (1989)
10.1016/0003-9861(80)90323-9 / Archs Biochem. Biophys. / Spin trapping of superoxide and hydroxyl radical: practical aspects by Finkelstein (1980)
10.1016/0306-4522(86)90043-6 / Neuroscience / In vitro neurotoxicity of excitatory amino acid analogues during cerebellar development by Garthwaite (1986)
10.1111/j.1460-9568.1991.tb01669.x / Eur. J. Neurosci. / Mechanisms of AMPA neurotoxicity in rat brain slices by Garthwaite (1991)
10.3171/jns.1988.68.3.0462 / J. Neurosurg. / Effects of the 21-aminosteroid U7400F on post traumatic spinal cord ischemia in cats by Hall (1988)
10.1016/0166-2236(85)90010-4 / Trends Neurosci. / Oxygen radicals and the nervous system by Halliwell (1985)
10.1042/bj2810419 / Biochem. J. / Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide by Hogg (1992)
10.1038/364535a0 / Nature / NMDA-dependent superoxide production and neurotoxicity by Lafon-Cazal (1993)
10.1016/0306-4522(93)90254-D / Neuroscience / Contributory mechanisms in the causation of neurodegenerative disorders by Lees (1993)
{'key': '10.1016/0028-3908(93)90020-4_BIB28', 'first-page': '1109', 'article-title': 'Chronic NO synthase inhibition fails to protect hippocampal neurones against NMDA toxicity', 'volume': '3', 'author': 'Lerner-Natoli', 'year': '1992', 'journal-title': 'Neuro Report'} / Neuro Report / Chronic NO synthase inhibition fails to protect hippocampal neurones against NMDA toxicity by Lerner-Natoli (1992)
10.1016/0092-8674(92)90301-R / Cell / Nitric oxide, a novel biological messenger by Lowenstein (1992)
10.1016/0896-6273(92)90087-T / Neuron / Nitric oxide induced blockade of NMDA receptors by Manzoni (1992)
10.1016/0166-2236(87)90025-7 / Trends Neurosci. / Glutamate dysfunction in Alzheimer's disease: an hypothesis by Maragos (1992)
10.1111/j.1460-9568.1992.tb00892.x / Eur. J. Neurosci. / A nitric oxide-synthase activity selectively stimulated by NMDA receptors via protein kinase C activation in mouse striatal neurons by Marin (1992)
10.1016/0165-6147(90)90184-A / Trends Pharmac. Sci. / Excitatory amino acid neurotoxicity and neurodegenerative disease by Meldrum (1990)
10.1016/0165-0173(89)90002-7 / Brain Res. Rev. / Calcium, neuronal hyperexcitability and ischemic injury by Meyer (1989)
10.1097/00001756-199206000-00020 / NeuroReport / Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions by Moncada (1992)
10.1016/0896-6273(90)90302-V / Neuron / 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures by Monyer (1990)
10.1042/bj2880597 / Biochem. J. / NO accounts completely for the oxygenated nitrogen species generated by enzymic l-arginine oxygenation by Mülsch (1992)
10.1016/0014-2999(91)90862-K / Eur. J. Pharmac. / Nitric oxide mediates neuronal death after focal ischemia in the mouse by Nowicki (1991)
10.1002/ddr.430170406 / Drug Dev. Res. / Excitotoxicity and N-methyl-d-aspartate receptors by Olney (1989)
10.1016/0304-3940(92)90225-V / Neurosci. Lett. / Blockade of nitric oxide formation does not prevent glutamate-induced neurotoxicity in neuronal cultures from rat hippocampus by Pauwels (1992)
10.1016/0003-2697(89)90002-X / Analyt. Biochem. / Problems associated with spin trapping oxygen-centered free radicals in biological systems by Pou (1989)
10.1016/S0021-9258(20)64313-7 / J. Biol. Chem. / Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide by Radi (1991)
10.1016/0003-9861(91)90224-7 / Archs Biochem. Biophys. / Peroxynitrite-induced membrane lipid peroxidation. The cytotoxic potential of superoxide and nitric oxide by Radi (1991)
{'key': '10.1016/0028-3908(93)90020-4_BIB44', 'article-title': 'l-Nitroarginine, an inhibitor of NO synthase, dramatically worsens limbic epilepsy in rats', 'author': 'Rondouin', 'year': '1993', 'journal-title': 'NeuroReport'} / NeuroReport / l-Nitroarginine, an inhibitor of NO synthase, dramatically worsens limbic epilepsy in rats by Rondouin (1993)
10.1038/362059a0 / Nature / Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis by Rosen (1993)
10.1002/ana.410190202 / Ann. Neurol. / Glutamate and pathophysiology of hypoxic-ischemic brain damage by Rothman (1986)
10.1159/000108829 / Cerebrovasc. Dis. / N-Methyl-d-aspartate receptor antagonists: a novel therapeutic perspective for the treatment of ischemic brain injury by Scatton (1991)
{'key': '10.1016/0028-3908(93)90020-4_BIB48', 'first-page': '165', 'article-title': 'Free radicals and brain damage', 'volume': '1', 'author': 'Siesjö', 'year': '1989', 'journal-title': 'Cerebrovasc. Brain Metab. Rev.'} / Cerebrovasc. Brain Metab. Rev. / Free radicals and brain damage by Siesjö (1989)
10.1126/science.3603037 / Science / Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin by Spencer (1987)
{'key': '10.1016/0028-3908(93)90020-4_BIB50', 'first-page': '1155', 'article-title': 'Cytotoxic effect of brain macrophages on developing neurons', 'volume': '3', 'author': 'Thery', 'year': '1991', 'journal-title': 'Eur. J. Pharmac.'} / Eur. J. Pharmac. / Cytotoxic effect of brain macrophages on developing neurons by Thery (1991)
10.1111/j.1471-4159.1989.tb01870.x / J. Neurochem. / Endogenous amino acid release from cultured cerebellar neuronal cells: effect of tetanus toxin on glutamate release by Van-Vliet (1989)

Dates

Type	When
Created	22 years, 8 months ago (Dec. 14, 2002, 1:52 p.m.)
Deposited	4 years, 2 months ago (June 1, 2021, 7:55 p.m.)
Indexed	5 hours, 1 minute ago (Aug. 30, 2025, 12:18 p.m.)
Issued	31 years, 9 months ago (Nov. 1, 1993)
Published	31 years, 9 months ago (Nov. 1, 1993)
Published Print	31 years, 9 months ago (Nov. 1, 1993)

Funders 0

None

BibTeX

@article{Lafon_Cazal_1993, title={Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells}, volume={32}, ISSN={0028-3908}, url={http://dx.doi.org/10.1016/0028-3908(93)90020-4}, DOI={10.1016/0028-3908(93)90020-4}, number={11}, journal={Neuropharmacology}, publisher={Elsevier BV}, author={Lafon-Cazal, Mireille and Culcasi, Marcel and Gaven, Florence and Pietri, Sylvia and Bockaert, Joël}, year={1993}, month=nov, pages={1259–1266} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        30
      ]
    ],
    "date-time": "2025-08-30T16:18:38Z",
    "timestamp": 1756570718244
  },
  "reference-count": 51,
  "publisher": "Elsevier BV",
  "issue": "11",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1993,
            11,
            1
          ]
        ],
        "date-time": "1993-11-01T00:00:00Z",
        "timestamp": 752112000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1993,
        11
      ]
    ]
  },
  "DOI": "10.1016/0028-3908(93)90020-4",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        12,
        14
      ]
    ],
    "date-time": "2002-12-14T18:52:00Z",
    "timestamp": 1039891920000
  },
  "page": "1259-1266",
  "source": "Crossref",
  "is-referenced-by-count": 161,
  "title": "Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells",
  "prefix": "10.1016",
  "volume": "32",
  "author": [
    {
      "given": "Mireille",
      "family": "Lafon-Cazal",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Marcel",
      "family": "Culcasi",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Florence",
      "family": "Gaven",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Sylvia",
      "family": "Pietri",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Jo\u00ebl",
      "family": "Bockaert",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "80",
      "DOI": "10.1016/0022-510X(92)90191-M",
      "article-title": "Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex",
      "volume": "108",
      "author": "Beal",
      "year": "1992",
      "journal-title": "J. Neurol. Sci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB2",
      "first-page": "1620",
      "article-title": "Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide",
      "volume": "87",
      "author": "Beckman",
      "year": "1990"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB3",
      "first-page": "43",
      "article-title": "Les canaux ioniques dans 1'anoxie c\u00e9r\u00e9-brale: cibles possibles d'agents protecteurs",
      "volume": "7",
      "author": "Ben-Ari",
      "year": "1991",
      "journal-title": "M\u00e9d. Sci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "3",
      "DOI": "10.1016/0896-6273(92)90104-L",
      "article-title": "Nitric oxide, a novel neuronal messenger",
      "volume": "8",
      "author": "Bredt",
      "year": "1992",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "714",
      "DOI": "10.1038/351714a0",
      "article-title": "Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase",
      "volume": "351",
      "author": "Bredt",
      "year": "1991",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB6",
      "first-page": "444",
      "article-title": "Nitric oxide: an endogenous anticonvulsant substance",
      "volume": "4",
      "author": "Buisson",
      "year": "1993",
      "journal-title": "Neuro Report"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "389",
      "DOI": "10.1016/0891-5849(93)90088-C",
      "article-title": "Superoxide and nitric oxide cooperation in hypoxia/reoxygenation-induced neuron injury",
      "volume": "14",
      "author": "Cazevieille Muller",
      "year": "1993",
      "journal-title": "Free Rad. Biol. Med."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "366",
      "DOI": "10.1007/BF00581130",
      "article-title": "Atrial natriuretic peptide effects on cyclic GMP and cyclic AMP contents in microdissected glomeruli and segments of the rat and rabbit nephron",
      "volume": "408",
      "author": "Chabardesse",
      "year": "1987",
      "journal-title": "Pl\u00fcgers Arch."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "465",
      "DOI": "10.1016/0166-2236(88)90200-7",
      "article-title": "Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage",
      "volume": "11",
      "author": "Choi",
      "year": "1988",
      "journal-title": "Trends Neurosci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "623",
      "DOI": "10.1016/0896-6273(88)90162-6",
      "article-title": "Glutamate neurotoxicity and disease of the nervous system",
      "volume": "1",
      "author": "Choi",
      "year": "1988",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "2493",
      "DOI": "10.1523/JNEUROSCI.10-08-02493.1990",
      "article-title": "Cerebral hypoxia: some new approaches and unanswered questions",
      "volume": "10",
      "author": "Choi",
      "year": "1990",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "2651",
      "DOI": "10.1523/JNEUROSCI.13-06-02651.1993",
      "article-title": "Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures",
      "volume": "13",
      "author": "Dawson",
      "year": "1993",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB13",
      "first-page": "6368",
      "article-title": "Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures",
      "volume": "88",
      "author": "Dawson",
      "year": "1991"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "456",
      "DOI": "10.1016/S0006-291X(05)81441-X",
      "article-title": "Absence of implication of l-argininenitric oxide pathway on neuronal cell injury induced by l-glutamate or hypoxia",
      "volume": "181",
      "author": "Demerl\u00e9-Pellardy",
      "year": "1991",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "25",
      "DOI": "10.1002/jnr.490270105",
      "article-title": "Rapid, sensitive and simple method for the quantification of both neurotoxic and neurotrophic effects of NMDA on cultured cerebellar granule cells",
      "volume": "27",
      "author": "Didier",
      "year": "1990",
      "journal-title": "J. Neurosci. Res."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "45",
      "DOI": "10.1111/j.1600-0404.1992.tb08052.x",
      "article-title": "Protection against ischemic hippocampal CA1 damage in the rat with a new non-NMDA antagonist, NBQX",
      "volume": "86",
      "author": "Diemer",
      "year": "1992",
      "journal-title": "Acta Neurol. Scand."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "334",
      "DOI": "10.1016/0165-6147(90)90238-4",
      "article-title": "Excitatory amino acid receptors in epilepsy",
      "volume": "11",
      "author": "Dingledine",
      "year": "1990",
      "journal-title": "Trends Pharmac. Sci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "311",
      "DOI": "10.1016/0014-2999(90)90623-E",
      "article-title": "Nanomolar NG-nitroarginine inhibits NMDA-induced cyclic GMP formation in rat cerebellum",
      "volume": "184",
      "author": "East",
      "year": "1990",
      "journal-title": "Eur. J. Pharmac."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "798",
      "DOI": "10.1126/science.2567056",
      "article-title": "The role of excitatory amino-acids and NMDA receptors in traumatic brain injury",
      "volume": "244",
      "author": "Faden",
      "year": "1989",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1016/0003-9861(80)90323-9",
      "article-title": "Spin trapping of superoxide and hydroxyl radical: practical aspects",
      "volume": "200",
      "author": "Finkelstein",
      "year": "1980",
      "journal-title": "Archs Biochem. Biophys."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "755",
      "DOI": "10.1016/0306-4522(86)90043-6",
      "article-title": "In vitro neurotoxicity of excitatory amino acid analogues during cerebellar development",
      "volume": "17",
      "author": "Garthwaite",
      "year": "1986",
      "journal-title": "Neuroscience"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "729",
      "DOI": "10.1111/j.1460-9568.1991.tb01669.x",
      "article-title": "Mechanisms of AMPA neurotoxicity in rat brain slices",
      "volume": "3",
      "author": "Garthwaite",
      "year": "1991",
      "journal-title": "Eur. J. Neurosci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "462",
      "DOI": "10.3171/jns.1988.68.3.0462",
      "article-title": "Effects of the 21-aminosteroid U7400F on post traumatic spinal cord ischemia in cats",
      "volume": "68",
      "author": "Hall",
      "year": "1988",
      "journal-title": "J. Neurosurg."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "22",
      "DOI": "10.1016/0166-2236(85)90010-4",
      "article-title": "Oxygen radicals and the nervous system",
      "volume": "8",
      "author": "Halliwell",
      "year": "1985",
      "journal-title": "Trends Neurosci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "419",
      "DOI": "10.1042/bj2810419",
      "article-title": "Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide",
      "volume": "281",
      "author": "Hogg",
      "year": "1992",
      "journal-title": "Biochem. J."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "535",
      "DOI": "10.1038/364535a0",
      "article-title": "NMDA-dependent superoxide production and neurotoxicity",
      "volume": "364",
      "author": "Lafon-Cazal",
      "year": "1993",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "287",
      "DOI": "10.1016/0306-4522(93)90254-D",
      "article-title": "Contributory mechanisms in the causation of neurodegenerative disorders",
      "volume": "54",
      "author": "Lees",
      "year": "1993",
      "journal-title": "Neuroscience"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB28",
      "first-page": "1109",
      "article-title": "Chronic NO synthase inhibition fails to protect hippocampal neurones against NMDA toxicity",
      "volume": "3",
      "author": "Lerner-Natoli",
      "year": "1992",
      "journal-title": "Neuro Report"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "705",
      "DOI": "10.1016/0092-8674(92)90301-R",
      "article-title": "Nitric oxide, a novel biological messenger",
      "volume": "70",
      "author": "Lowenstein",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "653",
      "DOI": "10.1016/0896-6273(92)90087-T",
      "article-title": "Nitric oxide induced blockade of NMDA receptors",
      "volume": "8",
      "author": "Manzoni",
      "year": "1992",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "65",
      "DOI": "10.1016/0166-2236(87)90025-7",
      "article-title": "Glutamate dysfunction in Alzheimer's disease: an hypothesis",
      "volume": "10",
      "author": "Maragos",
      "year": "1992",
      "journal-title": "Trends Neurosci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "425",
      "DOI": "10.1111/j.1460-9568.1992.tb00892.x",
      "article-title": "A nitric oxide-synthase activity selectively stimulated by NMDA receptors via protein kinase C activation in mouse striatal neurons",
      "volume": "4",
      "author": "Marin",
      "year": "1992",
      "journal-title": "Eur. J. Neurosci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "379",
      "DOI": "10.1016/0165-6147(90)90184-A",
      "article-title": "Excitatory amino acid neurotoxicity and neurodegenerative disease",
      "volume": "11",
      "author": "Meldrum",
      "year": "1990",
      "journal-title": "Trends Pharmac. Sci."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "227",
      "DOI": "10.1016/0165-0173(89)90002-7",
      "article-title": "Calcium, neuronal hyperexcitability and ischemic injury",
      "volume": "14",
      "author": "Meyer",
      "year": "1989",
      "journal-title": "Brain Res. Rev."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "530",
      "DOI": "10.1097/00001756-199206000-00020",
      "article-title": "Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions",
      "volume": "3",
      "author": "Moncada",
      "year": "1992",
      "journal-title": "NeuroReport"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "121",
      "DOI": "10.1016/0896-6273(90)90302-V",
      "article-title": "21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures",
      "volume": "5",
      "author": "Monyer",
      "year": "1990",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "597",
      "DOI": "10.1042/bj2880597",
      "article-title": "NO accounts completely for the oxygenated nitrogen species generated by enzymic l-arginine oxygenation",
      "volume": "288",
      "author": "M\u00fclsch",
      "year": "1992",
      "journal-title": "Biochem. J."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "339",
      "DOI": "10.1016/0014-2999(91)90862-K",
      "article-title": "Nitric oxide mediates neuronal death after focal ischemia in the mouse",
      "volume": "204",
      "author": "Nowicki",
      "year": "1991",
      "journal-title": "Eur. J. Pharmac."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "299",
      "DOI": "10.1002/ddr.430170406",
      "article-title": "Excitotoxicity and N-methyl-d-aspartate receptors",
      "volume": "17",
      "author": "Olney",
      "year": "1989",
      "journal-title": "Drug Dev. Res."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "27",
      "DOI": "10.1016/0304-3940(92)90225-V",
      "article-title": "Blockade of nitric oxide formation does not prevent glutamate-induced neurotoxicity in neuronal cultures from rat hippocampus",
      "volume": "143",
      "author": "Pauwels",
      "year": "1992",
      "journal-title": "Neurosci. Lett."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1016/0003-2697(89)90002-X",
      "article-title": "Problems associated with spin trapping oxygen-centered free radicals in biological systems",
      "volume": "177",
      "author": "Pou",
      "year": "1989",
      "journal-title": "Analyt. Biochem."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "4244",
      "DOI": "10.1016/S0021-9258(20)64313-7",
      "article-title": "Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide",
      "volume": "266",
      "author": "Radi",
      "year": "1991",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "481",
      "DOI": "10.1016/0003-9861(91)90224-7",
      "article-title": "Peroxynitrite-induced membrane lipid peroxidation. The cytotoxic potential of superoxide and nitric oxide",
      "volume": "288",
      "author": "Radi",
      "year": "1991",
      "journal-title": "Archs Biochem. Biophys."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB44",
      "article-title": "l-Nitroarginine, an inhibitor of NO synthase, dramatically worsens limbic epilepsy in rats",
      "author": "Rondouin",
      "year": "1993",
      "journal-title": "NeuroReport"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "51",
      "DOI": "10.1038/362059a0",
      "article-title": "Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis",
      "volume": "362",
      "author": "Rosen",
      "year": "1993",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "105",
      "DOI": "10.1002/ana.410190202",
      "article-title": "Glutamate and pathophysiology of hypoxic-ischemic brain damage",
      "volume": "19",
      "author": "Rothman",
      "year": "1986",
      "journal-title": "Ann. Neurol."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "121",
      "DOI": "10.1159/000108829",
      "article-title": "N-Methyl-d-aspartate receptor antagonists: a novel therapeutic perspective for the treatment of ischemic brain injury",
      "volume": "1",
      "author": "Scatton",
      "year": "1991",
      "journal-title": "Cerebrovasc. Dis."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB48",
      "first-page": "165",
      "article-title": "Free radicals and brain damage",
      "volume": "1",
      "author": "Siesj\u00f6",
      "year": "1989",
      "journal-title": "Cerebrovasc. Brain Metab. Rev."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "517",
      "DOI": "10.1126/science.3603037",
      "article-title": "Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin",
      "volume": "237",
      "author": "Spencer",
      "year": "1987",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB50",
      "first-page": "1155",
      "article-title": "Cytotoxic effect of brain macrophages on developing neurons",
      "volume": "3",
      "author": "Thery",
      "year": "1991",
      "journal-title": "Eur. J. Pharmac."
    },
    {
      "key": "10.1016/0028-3908(93)90020-4_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "1229",
      "DOI": "10.1111/j.1471-4159.1989.tb01870.x",
      "article-title": "Endogenous amino acid release from cultured cerebellar neuronal cells: effect of tetanus toxin on glutamate release",
      "volume": "52",
      "author": "Van-Vliet",
      "year": "1989",
      "journal-title": "J. Neurochem."
    }
  ],
  "container-title": "Neuropharmacology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:0028390893900204?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:0028390893900204?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        6,
        1
      ]
    ],
    "date-time": "2021-06-01T23:55:34Z",
    "timestamp": 1622591734000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/0028390893900204"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1993,
        11
      ]
    ]
  },
  "references-count": 51,
  "journal-issue": {
    "issue": "11",
    "published-print": {
      "date-parts": [
        [
          1993,
          11
        ]
      ]
    }
  },
  "alternative-id": [
    "0028390893900204"
  ],
  "URL": "http://dx.doi.org/10.1016/0028-3908(93)90020-4",
  "relation": {},
  "ISSN": [
    "0028-3908"
  ],
  "subject": [],
  "container-title-short": "Neuropharmacology",
  "published": {
    "date-parts": [
      [
        1993,
        11
      ]
    ]
  }
}