DOI: 10.1016/0026-0495(76)90149-9. Delayed clearance of chylomicron remnants following vitamin-A-containing oral fat loads in broad-β disease (type III hyperlipoproteinemia)

Delayed clearance of chylomicron remnants following vitamin-A-containing oral fat loads in broad-β disease (type III hyperlipoproteinemia)

10.1016/0026-0495(76)90149-9

Crossref journal-article

Elsevier BV

Metabolism (78)

Bibliography

Hazzard, W. R., & Bierman, E. L. (1976). Delayed clearance of chylomicron remnants following vitamin-A-containing oral fat loads in broad-Î² disease (type III hyperlipoproteinemia). Metabolism, 25(7), 777â801.

Authors 2

William R. Hazzard (first)
Edwin L. Bierman (additional)

References 49 Referenced 130

10.1016/S0022-2275(20)39346-9 / J Lipid Res / Characterization of subfractions of triglyceride-rich lipoproteins separated by gel chromatography from blood plasma of normolipemic and hyperlipemic by Sata (1972)
10.1172/JCI106700 / J Clin Invest / Synthesis and transport of lipoprotein particles by intestinal absorptive cells in man by Tytgat (1971)
10.1172/JCI106203 / J Clin Invest / Very low density lipoproteins in intestinal lymph: Role in triglyceride and cholesterol transport during fat absorption by Ockner (1969)
10.1056/NEJM196702022760507 / N Engl J Med / Fat transport in lipoproteins—an integrated approach to mechanisms and disorders by Fredrickson (1967)
{'key': '10.1016/0026-0495(76)90149-9_BIB5', 'first-page': '117', 'article-title': 'Pathogenesis, differentiation, and management of hypertriglyceridemia', 'volume': 'vol 15', 'author': 'Havel', 'year': '1969'} / Pathogenesis, differentiation, and management of hypertriglyceridemia by Havel (1969)
Windmueller HG, Levy RI: Production of β-lipoprotein by intestine in the rat. J Biol Chem 243: 4878–4884 (10.1016/S0021-9258(18)93198-4)
10.1172/JCI105140 / J Clin Invest / Characterization of fat particles in plasma of hyperlipemic subjects maintained on fat-free high-carbohydrate diets by Bierman (1965)
10.1016/0026-0495(68)90047-4 / Metabolism / Relation between dietary fat and fatty acid composition of “endogenous” and “exogenous” very low density lipoprotein triglycerides (D < 1.006) by Edelin (1968)
10.1172/JCI105719 / J Clin Invest / Turnover of plasma cholesterol in man by Goodman (1968)
10.1016/0005-2760(72)90216-0 / Biochim Biophys Acta / The metabolism of very low density lipoproteins II. Studies on the transfer of apoproteins between plasma lipoproteins by Eisenberg (1972)
10.1172/JCI105526 / J Clin Invest / Tissue lipoprotein lipase in normal individuals and individuals with exogenous hypertriglyceridemia and the relationship of this enzyme to assimilation of fat by Harlan (1967)
{'key': '10.1016/0026-0495(76)90149-9_BIB12', 'series-title': 'The Metabolic Basis of Inherited Disease', 'first-page': '595', 'article-title': 'Familial hyperlipoproteinemia', 'author': 'Fredrickson', 'year': '1972'} / The Metabolic Basis of Inherited Disease / Familial hyperlipoproteinemia by Fredrickson (1972)
10.1001/archinte.123.3.220 / Arch Intern Med / Hypertriglyceridemia, diabetes mellitus, and coronary vessel disease by Levy (1969)
10.7326/0003-4819-82-2-141 / Ann Intern Med / Broad-β disease (type III hyperlipoproteinemia) in a large kindred: evidence for a monogenic mechanism by Hazzard (1975)
10.7326/0003-4819-82-2-158 / Ann Intern Med / The biochemical, clinical, and genetic features of type III hyperlipoproteinemia by Morganroth (1975)
{'key': '10.1016/0026-0495(76)90149-9_BIB16', 'first-page': '1670', 'article-title': 'Metabolism and function of Vitamin A1', 'volume': '28', 'author': 'Olson', 'year': '1969'} / Metabolism and function of Vitamin A1 by Olson (1969)
10.1172/JCI105468 / J Clin Invest / The intestinal absorption and metabolism of vitamin A and betacarotene in man by Goodman (1966)
10.1016/S0022-2275(20)39309-3 / J Lipid Res / Tissue distribution and metabolism of newly absorbed vitamin A in the rat by Goodman (1965)
{'key': '10.1016/0026-0495(76)90149-9_BIB19', 'series-title': 'Proc of International Workshop-Conference on Atherosclerosis', 'article-title': 'Use of esterified retinol to trace the degration of chylomicrons in cholesterol-fed rabbits. Proc of Inmicrons in cholesterol-fed rabbits', 'author': 'Ross', 'year': '1975'} / Proc of International Workshop-Conference on Atherosclerosis / Use of esterified retinol to trace the degration of chylomicrons in cholesterol-fed rabbits. Proc of Inmicrons in cholesterol-fed rabbits by Ross (1975)
10.1001/jama.214.6.1097 / JAMA / Vitamin A physiology by Roels (1970)
10.1172/JCI105889 / J Clin Invest / Retinolbinding protein: The transport protein for vitamin A in human plasma by Kanai (1968)
10.1016/0026-0495(75)90128-6 / Metabolism / Broad-β disease vs. endogenous hypertriglyceridemia: levels and lipid composition of chylomicrons and very low density lipoproteins during fatfree feeding and alimentary lipemia by Hazzard (1975)
10.1172/JCI107331 / J Clin Invest / Hyperlipidemia in coronary heart disease. I. Lipid levels in 500 survivors of myocardial infarction by Goldstein (1973)
10.1172/JCI106403 / J Clin Invest / Abnormal lipid composition of chylomicrons in broad-β disease (type III hyperlipoproteinemia) by Hazzard (1970)
10.1016/0026-0495(72)90031-5 / Metabolism / Abnormal lipid composition of very low density lipoproteins in diagnosis of broad-β disease (type III hyperlipoproteinemia) by Hazzard (1972)
{'key': '10.1016/0026-0495(76)90149-9_BIB26', 'first-page': '631', 'article-title': 'The effect of heparin infusion on plasma triglyceride in vivo and in vitro with a method for calculating triglyceride turnover', 'volume': '73', 'author': 'Porte', 'year': '1969', 'journal-title': 'J Lab Clin Med'} / J Lab Clin Med / The effect of heparin infusion on plasma triglyceride in vivo and in vitro with a method for calculating triglyceride turnover by Porte (1969)
10.1172/JCI107332 / J Clin Invest / Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder: Combined hyperlipidemia by Goldstein (1973)
10.1172/JCI107334 / J Clin Invest / Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man by Brunzell (1973)
10.1172/JCI104684 / J Clin Invest / Heterogeneity of fat particles in plasma during alimentary lipemia by Bierman (1962)
10.1016/S0022-2275(20)43114-1 / J Lipid Res / The plasma lecithin: cholesterol acyltransferase reaction by Glomset (1968)
{'key': '10.1016/0026-0495(76)90149-9_BIB31', 'series-title': 'Blood Lipids and Lipoproteins', 'first-page': '181', 'article-title': 'The isolation and quantitative analysis of serum lipoproteins', 'author': 'Lindgren', 'year': '1972'} / Blood Lipids and Lipoproteins / The isolation and quantitative analysis of serum lipoproteins by Lindgren (1972)
10.1016/S0022-2275(20)42650-1 / J Lipid Res / Particle size and protein content of six fractions of the Sf > 20 plasma lipoproteins isolated by density gradient centrifugation by Lossow (1969)
{'key': '10.1016/0026-0495(76)90149-9_BIB33', 'first-page': '239', 'article-title': 'The spectrum of electrophoretic mobility of very low density lipoproteins: Role of slower-migrating species in endogenous lipemia and broad-β disease', 'volume': '86', 'author': 'Hazzard', 'year': '1975', 'journal-title': 'J Lab Clin Med'} / J Lab Clin Med / The spectrum of electrophoretic mobility of very low density lipoproteins: Role of slower-migrating species in endogenous lipemia and broad-β disease by Hazzard (1975)
10.1016/S0368-1319(63)80012-5 / J Atheroscler Res / Determination of serum triglycerides by Carlson (1963)
10.2337/diab.10.6.432 / Diabetes / The hyperlipemic effect of a low-fat, high-carbohydrate diet in diabetic subjects by Bierman (1961)
{'key': '10.1016/0026-0495(76)90149-9_BIB36', 'article-title': 'Vitamin A', 'volume': 'vol 6', 'author': 'Roels', 'year': '1967'} / Vitamin A by Roels (1967)
{'key': '10.1016/0026-0495(76)90149-9_BIB37', 'first-page': '313', 'author': 'Remington', 'year': '1970'} by Remington (1970)
10.7326/0003-4819-82-2-273 / Ann Intern Med / Hyperlipoproteinemia: problems in diagnosis and challenges posed by the “type III” disorder by Havel (1975)
10.1172/JCI106546 / J Clin Invest / On the lipoprotein abnormality in type III hyperlipoproteinemia by Quarfordt (1971)
10.7326/0003-4819-82-2-150 / Ann Intern Med / Type III hyperlipoproteinemia: an analysis of two contemporary definitions by Fredrickson (1975)
{'key': '10.1016/0026-0495(76)90149-9_BIB41', 'first-page': '2015', 'article-title': 'Primary dysbetalipoproteinemia: predominance of a specific apolipoprotein species in triglyceride-rich lipoproteins', 'volume': '70', 'author': 'Havel', 'year': '1973'} / Primary dysbetalipoproteinemia: predominance of a specific apolipoprotein species in triglyceride-rich lipoproteins by Havel (1973)
10.1016/0005-2760(73)90138-0 / Biochim Biophys Acta / On the metabolic conversion of human plasma very low density lipoprotein to low density lipoprotein by Eisenberg (1973)
{'issue': 'Suppl. III', 'key': '10.1016/0026-0495(76)90149-9_BIB43', 'first-page': '114', 'article-title': 'A mathematical model for apoprotein kinetics in normal and hyperlipemic patients', 'volume': '49–50', 'author': 'Hall', 'year': '1974', 'journal-title': 'Circulation'} / Circulation / A mathematical model for apoprotein kinetics in normal and hyperlipemic patients by Hall (1974)
{'issue': 'Suppl. II', 'key': '10.1016/0026-0495(76)90149-9_BIB44', 'first-page': '56', 'article-title': 'Abnormal metabolism of very low density lipoproteins in type III hyperlipoproteinemia', 'volume': '44', 'author': 'Bilheimer', 'year': '1971', 'journal-title': 'Circulation'} / Circulation / Abnormal metabolism of very low density lipoproteins in type III hyperlipoproteinemia by Bilheimer (1971)
{'issue': 'Suppl. II', 'key': '10.1016/0026-0495(76)90149-9_BIB45', 'first-page': '149', 'article-title': 'Type III hyperlipidemia: Implications of paradoxical hypolipidemic response to estrogen', 'volume': '52', 'author': 'Gagne', 'year': '1975', 'journal-title': 'Circulation'} / Circulation / Type III hyperlipidemia: Implications of paradoxical hypolipidemic response to estrogen by Gagne (1975)
10.1172/JCI105303 / J Clin Invest / The differentiation of exogenous and endogenous hyperlipemia by paper electrophoresis by Lees (1965)
10.1210/jcem-31-6-640 / J Clin Endocrinol / Determination of the endogenous component of alimentary lipemia by Sullivan (1970)
10.1016/0005-2760(72)90045-8 / Biochim Biophys Acta / On the apoprotein composition of human plasma very low density lipoprotein subfractions by Eisenberg (1972)
10.1016/S0022-2275(20)39291-9 / J Lipid Res / Use of constant composition polyvinylpyrollidone columns to study the interaction of fat particles with plasma by O'Hara (1966)

Dates

Type	When
Created	20 years, 6 months ago (Feb. 9, 2005, 4:14 a.m.)
Deposited	4 years, 2 months ago (July 4, 2021, 6:28 p.m.)
Indexed	1 day, 22 hours ago (Sept. 4, 2025, 10:05 a.m.)
Issued	49 years, 2 months ago (July 1, 1976)
Published	49 years, 2 months ago (July 1, 1976)
Published Print	49 years, 2 months ago (July 1, 1976)

Funders 0

None

BibTeX

@article{Hazzard_1976, title={Delayed clearance of chylomicron remnants following vitamin-A-containing oral fat loads in broad-β disease (type III hyperlipoproteinemia)}, volume={25}, ISSN={0026-0495}, url={http://dx.doi.org/10.1016/0026-0495(76)90149-9}, DOI={10.1016/0026-0495(76)90149-9}, number={7}, journal={Metabolism}, publisher={Elsevier BV}, author={Hazzard, William R. and Bierman, Edwin L.}, year={1976}, month=jul, pages={777–801} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        9,
        4
      ]
    ],
    "date-time": "2025-09-04T14:05:59Z",
    "timestamp": 1756994759364
  },
  "reference-count": 49,
  "publisher": "Elsevier BV",
  "issue": "7",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1976,
            7,
            1
          ]
        ],
        "date-time": "1976-07-01T00:00:00Z",
        "timestamp": 205027200000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1976,
        7
      ]
    ]
  },
  "DOI": "10.1016/0026-0495(76)90149-9",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        2,
        9
      ]
    ],
    "date-time": "2005-02-09T09:14:44Z",
    "timestamp": 1107940484000
  },
  "page": "777-801",
  "source": "Crossref",
  "is-referenced-by-count": 130,
  "title": "Delayed clearance of chylomicron remnants following vitamin-A-containing oral fat loads in broad-\u03b2 disease (type III hyperlipoproteinemia)",
  "prefix": "10.1016",
  "volume": "25",
  "author": [
    {
      "given": "William R.",
      "family": "Hazzard",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Edwin L.",
      "family": "Bierman",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "757",
      "DOI": "10.1016/S0022-2275(20)39346-9",
      "article-title": "Characterization of subfractions of triglyceride-rich lipoproteins separated by gel chromatography from blood plasma of normolipemic and hyperlipemic",
      "volume": "13",
      "author": "Sata",
      "year": "1972",
      "journal-title": "J Lipid Res"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "2065",
      "DOI": "10.1172/JCI106700",
      "article-title": "Synthesis and transport of lipoprotein particles by intestinal absorptive cells in man",
      "volume": "50",
      "author": "Tytgat",
      "year": "1971",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "2367",
      "DOI": "10.1172/JCI106203",
      "article-title": "Very low density lipoproteins in intestinal lymph: Role in triglyceride and cholesterol transport during fat absorption",
      "volume": "48",
      "author": "Ockner",
      "year": "1969",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "32",
      "DOI": "10.1056/NEJM196702022760507",
      "article-title": "Fat transport in lipoproteins\u2014an integrated approach to mechanisms and disorders",
      "volume": "276",
      "author": "Fredrickson",
      "year": "1967",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB5",
      "first-page": "117",
      "article-title": "Pathogenesis, differentiation, and management of hypertriglyceridemia",
      "volume": "vol 15",
      "author": "Havel",
      "year": "1969"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB6",
      "doi-asserted-by": "crossref",
      "unstructured": "Windmueller HG, Levy RI: Production of \u03b2-lipoprotein by intestine in the rat. J Biol Chem 243: 4878\u20134884",
      "DOI": "10.1016/S0021-9258(18)93198-4"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "261",
      "DOI": "10.1172/JCI105140",
      "article-title": "Characterization of fat particles in plasma of hyperlipemic subjects maintained on fat-free high-carbohydrate diets",
      "volume": "44",
      "author": "Bierman",
      "year": "1965",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "544",
      "DOI": "10.1016/0026-0495(68)90047-4",
      "article-title": "Relation between dietary fat and fatty acid composition of \u201cendogenous\u201d and \u201cexogenous\u201d very low density lipoprotein triglycerides (D < 1.006)",
      "volume": "17",
      "author": "Edelin",
      "year": "1968",
      "journal-title": "Metabolism"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "231",
      "DOI": "10.1172/JCI105719",
      "article-title": "Turnover of plasma cholesterol in man",
      "volume": "47",
      "author": "Goodman",
      "year": "1968",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "94",
      "DOI": "10.1016/0005-2760(72)90216-0",
      "article-title": "The metabolism of very low density lipoproteins II. Studies on the transfer of apoproteins between plasma lipoproteins",
      "volume": "280",
      "author": "Eisenberg",
      "year": "1972",
      "journal-title": "Biochim Biophys Acta"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "239",
      "DOI": "10.1172/JCI105526",
      "article-title": "Tissue lipoprotein lipase in normal individuals and individuals with exogenous hypertriglyceridemia and the relationship of this enzyme to assimilation of fat",
      "volume": "46",
      "author": "Harlan",
      "year": "1967",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB12",
      "series-title": "The Metabolic Basis of Inherited Disease",
      "first-page": "595",
      "article-title": "Familial hyperlipoproteinemia",
      "author": "Fredrickson",
      "year": "1972"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "220",
      "DOI": "10.1001/archinte.123.3.220",
      "article-title": "Hypertriglyceridemia, diabetes mellitus, and coronary vessel disease",
      "volume": "123",
      "author": "Levy",
      "year": "1969",
      "journal-title": "Arch Intern Med"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "141",
      "DOI": "10.7326/0003-4819-82-2-141",
      "article-title": "Broad-\u03b2 disease (type III hyperlipoproteinemia) in a large kindred: evidence for a monogenic mechanism",
      "volume": "82",
      "author": "Hazzard",
      "year": "1975",
      "journal-title": "Ann Intern Med"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "158",
      "DOI": "10.7326/0003-4819-82-2-158",
      "article-title": "The biochemical, clinical, and genetic features of type III hyperlipoproteinemia",
      "volume": "82",
      "author": "Morganroth",
      "year": "1975",
      "journal-title": "Ann Intern Med"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB16",
      "first-page": "1670",
      "article-title": "Metabolism and function of Vitamin A1",
      "volume": "28",
      "author": "Olson",
      "year": "1969"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "1615",
      "DOI": "10.1172/JCI105468",
      "article-title": "The intestinal absorption and metabolism of vitamin A and betacarotene in man",
      "volume": "45",
      "author": "Goodman",
      "year": "1966",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "390",
      "DOI": "10.1016/S0022-2275(20)39309-3",
      "article-title": "Tissue distribution and metabolism of newly absorbed vitamin A in the rat",
      "volume": "6",
      "author": "Goodman",
      "year": "1965",
      "journal-title": "J Lipid Res"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB19",
      "series-title": "Proc of International Workshop-Conference on Atherosclerosis",
      "article-title": "Use of esterified retinol to trace the degration of chylomicrons in cholesterol-fed rabbits. Proc of Inmicrons in cholesterol-fed rabbits",
      "author": "Ross",
      "year": "1975"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "1097",
      "DOI": "10.1001/jama.214.6.1097",
      "article-title": "Vitamin A physiology",
      "volume": "214",
      "author": "Roels",
      "year": "1970",
      "journal-title": "JAMA"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "2025",
      "DOI": "10.1172/JCI105889",
      "article-title": "Retinolbinding protein: The transport protein for vitamin A in human plasma",
      "volume": "47",
      "author": "Kanai",
      "year": "1968",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "817",
      "DOI": "10.1016/0026-0495(75)90128-6",
      "article-title": "Broad-\u03b2 disease vs. endogenous hypertriglyceridemia: levels and lipid composition of chylomicrons and very low density lipoproteins during fatfree feeding and alimentary lipemia",
      "volume": "24",
      "author": "Hazzard",
      "year": "1975",
      "journal-title": "Metabolism"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "1533",
      "DOI": "10.1172/JCI107331",
      "article-title": "Hyperlipidemia in coronary heart disease. I. Lipid levels in 500 survivors of myocardial infarction",
      "volume": "52",
      "author": "Goldstein",
      "year": "1973",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "1853",
      "DOI": "10.1172/JCI106403",
      "article-title": "Abnormal lipid composition of chylomicrons in broad-\u03b2 disease (type III hyperlipoproteinemia)",
      "volume": "49",
      "author": "Hazzard",
      "year": "1970",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "1009",
      "DOI": "10.1016/0026-0495(72)90031-5",
      "article-title": "Abnormal lipid composition of very low density lipoproteins in diagnosis of broad-\u03b2 disease (type III hyperlipoproteinemia)",
      "volume": "21",
      "author": "Hazzard",
      "year": "1972",
      "journal-title": "Metabolism"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB26",
      "first-page": "631",
      "article-title": "The effect of heparin infusion on plasma triglyceride in vivo and in vitro with a method for calculating triglyceride turnover",
      "volume": "73",
      "author": "Porte",
      "year": "1969",
      "journal-title": "J Lab Clin Med"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "1544",
      "DOI": "10.1172/JCI107332",
      "article-title": "Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder: Combined hyperlipidemia",
      "volume": "52",
      "author": "Goldstein",
      "year": "1973",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "1577",
      "DOI": "10.1172/JCI107334",
      "article-title": "Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man",
      "volume": "52",
      "author": "Brunzell",
      "year": "1973",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "2254",
      "DOI": "10.1172/JCI104684",
      "article-title": "Heterogeneity of fat particles in plasma during alimentary lipemia",
      "volume": "41",
      "author": "Bierman",
      "year": "1962",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "155",
      "DOI": "10.1016/S0022-2275(20)43114-1",
      "article-title": "The plasma lecithin: cholesterol acyltransferase reaction",
      "volume": "9",
      "author": "Glomset",
      "year": "1968",
      "journal-title": "J Lipid Res"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB31",
      "series-title": "Blood Lipids and Lipoproteins",
      "first-page": "181",
      "article-title": "The isolation and quantitative analysis of serum lipoproteins",
      "author": "Lindgren",
      "year": "1972"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "68",
      "DOI": "10.1016/S0022-2275(20)42650-1",
      "article-title": "Particle size and protein content of six fractions of the Sf > 20 plasma lipoproteins isolated by density gradient centrifugation",
      "volume": "10",
      "author": "Lossow",
      "year": "1969",
      "journal-title": "J Lipid Res"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB33",
      "first-page": "239",
      "article-title": "The spectrum of electrophoretic mobility of very low density lipoproteins: Role of slower-migrating species in endogenous lipemia and broad-\u03b2 disease",
      "volume": "86",
      "author": "Hazzard",
      "year": "1975",
      "journal-title": "J Lab Clin Med"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "334",
      "DOI": "10.1016/S0368-1319(63)80012-5",
      "article-title": "Determination of serum triglycerides",
      "volume": "3",
      "author": "Carlson",
      "year": "1963",
      "journal-title": "J Atheroscler Res"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "432",
      "DOI": "10.2337/diab.10.6.432",
      "article-title": "The hyperlipemic effect of a low-fat, high-carbohydrate diet in diabetic subjects",
      "volume": "10",
      "author": "Bierman",
      "year": "1961",
      "journal-title": "Diabetes"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB36",
      "article-title": "Vitamin A",
      "volume": "vol 6",
      "author": "Roels",
      "year": "1967"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB37",
      "first-page": "313",
      "author": "Remington",
      "year": "1970"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "273",
      "DOI": "10.7326/0003-4819-82-2-273",
      "article-title": "Hyperlipoproteinemia: problems in diagnosis and challenges posed by the \u201ctype III\u201d disorder",
      "volume": "82",
      "author": "Havel",
      "year": "1975",
      "journal-title": "Ann Intern Med"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "754",
      "DOI": "10.1172/JCI106546",
      "article-title": "On the lipoprotein abnormality in type III hyperlipoproteinemia",
      "volume": "50",
      "author": "Quarfordt",
      "year": "1971",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "150",
      "DOI": "10.7326/0003-4819-82-2-150",
      "article-title": "Type III hyperlipoproteinemia: an analysis of two contemporary definitions",
      "volume": "82",
      "author": "Fredrickson",
      "year": "1975",
      "journal-title": "Ann Intern Med"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB41",
      "first-page": "2015",
      "article-title": "Primary dysbetalipoproteinemia: predominance of a specific apolipoprotein species in triglyceride-rich lipoproteins",
      "volume": "70",
      "author": "Havel",
      "year": "1973"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "361",
      "DOI": "10.1016/0005-2760(73)90138-0",
      "article-title": "On the metabolic conversion of human plasma very low density lipoprotein to low density lipoprotein",
      "volume": "326",
      "author": "Eisenberg",
      "year": "1973",
      "journal-title": "Biochim Biophys Acta"
    },
    {
      "issue": "Suppl. III",
      "key": "10.1016/0026-0495(76)90149-9_BIB43",
      "first-page": "114",
      "article-title": "A mathematical model for apoprotein kinetics in normal and hyperlipemic patients",
      "volume": "49\u201350",
      "author": "Hall",
      "year": "1974",
      "journal-title": "Circulation"
    },
    {
      "issue": "Suppl. II",
      "key": "10.1016/0026-0495(76)90149-9_BIB44",
      "first-page": "56",
      "article-title": "Abnormal metabolism of very low density lipoproteins in type III hyperlipoproteinemia",
      "volume": "44",
      "author": "Bilheimer",
      "year": "1971",
      "journal-title": "Circulation"
    },
    {
      "issue": "Suppl. II",
      "key": "10.1016/0026-0495(76)90149-9_BIB45",
      "first-page": "149",
      "article-title": "Type III hyperlipidemia: Implications of paradoxical hypolipidemic response to estrogen",
      "volume": "52",
      "author": "Gagne",
      "year": "1975",
      "journal-title": "Circulation"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "1968",
      "DOI": "10.1172/JCI105303",
      "article-title": "The differentiation of exogenous and endogenous hyperlipemia by paper electrophoresis",
      "volume": "44",
      "author": "Lees",
      "year": "1965",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "640",
      "DOI": "10.1210/jcem-31-6-640",
      "article-title": "Determination of the endogenous component of alimentary lipemia",
      "volume": "31",
      "author": "Sullivan",
      "year": "1970",
      "journal-title": "J Clin Endocrinol"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "329",
      "DOI": "10.1016/0005-2760(72)90045-8",
      "article-title": "On the apoprotein composition of human plasma very low density lipoprotein subfractions",
      "volume": "260",
      "author": "Eisenberg",
      "year": "1972",
      "journal-title": "Biochim Biophys Acta"
    },
    {
      "key": "10.1016/0026-0495(76)90149-9_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "264",
      "DOI": "10.1016/S0022-2275(20)39291-9",
      "article-title": "Use of constant composition polyvinylpyrollidone columns to study the interaction of fat particles with plasma",
      "volume": "7",
      "author": "O'Hara",
      "year": "1966",
      "journal-title": "J Lipid Res"
    }
  ],
  "container-title": "Metabolism",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:0026049576901499?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:0026049576901499?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        7,
        4
      ]
    ],
    "date-time": "2021-07-04T22:28:10Z",
    "timestamp": 1625437690000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/0026049576901499"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1976,
        7
      ]
    ]
  },
  "references-count": 49,
  "journal-issue": {
    "issue": "7",
    "published-print": {
      "date-parts": [
        [
          1976,
          7
        ]
      ]
    }
  },
  "alternative-id": [
    "0026049576901499"
  ],
  "URL": "http://dx.doi.org/10.1016/0026-0495(76)90149-9",
  "relation": {},
  "ISSN": [
    "0026-0495"
  ],
  "subject": [],
  "container-title-short": "Metabolism",
  "published": {
    "date-parts": [
      [
        1976,
        7
      ]
    ]
  }
}