10.1016/0014-5793(96)00583-2
Crossref journal-article
Wiley
FEBS Letters (311)
Abstract

The transport of proteins from the cytoplasm into the nucleus is a multistep process. The nuclear localization sequence (NLS) of a transport substrate associates with the heterodimeric NLS‐receptor which binds to a subset of proteins of the nuclear pore complex (NPC). Translocation through the NPC is energy‐DApenDAnt and requires the small GTPase Ran. Proteins that interact with Ran in either the GDP‐bound or the GTP‐bound state coordinate transfer through the NPC. Lastly, the NLS‐receptor/substrate complex and Ran reach the nuclear siDA of the NPC where the complex disassembles.

Bibliography

Schlenstedt, G. (1996). Protein import into the nucleus. FEBS Letters, 389(1), 75–79. Portico.

Authors 1
  1. Gabriel Schlenstedt (first)
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Dates
Type When
Created 23 years, 1 month ago (July 25, 2002, 1:55 p.m.)
Deposited 1 year, 11 months ago (Sept. 16, 2023, 6:24 a.m.)
Indexed 1 month, 3 weeks ago (July 4, 2025, 7:25 a.m.)
Issued 29 years, 2 months ago (June 24, 1996)
Published 29 years, 2 months ago (June 24, 1996)
Published Online 26 years, 5 months ago (March 8, 1999)
Published Print 29 years, 2 months ago (June 24, 1996)
Funders 0

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@article{Schlenstedt_1996, title={Protein import into the nucleus}, volume={389}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(96)00583-2}, DOI={10.1016/0014-5793(96)00583-2}, number={1}, journal={FEBS Letters}, publisher={Wiley}, author={Schlenstedt, Gabriel}, year={1996}, month=jun, pages={75–79} }