DOI: 10.1016/0014-5793(95)00159-7. Phase separation in cytoplasm, due to macromolecular crowding, is the basis for microcompartmentation

Phase separation in cytoplasm, due to macromolecular crowding, is the basis for microcompartmentation

10.1016/0014-5793(95)00159-7

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

The macromolecular diversity and concentrations in the fluid phase of cytoplasm constitute conditions necessary and sufficient for aqueous phase separation. Consequences of phase separation in cytoplasm, including its ‘compartmentation’, are inferred from analogies with the physicochemical properties of aqueous two‐phase systems and with the partitioning behavior of biomaterials in them.

Bibliography

Walter, H., & Brooks, D. E. (1995). Phase separation in cytoplasm, due to macromolecular crowding, is the basis for microcompartmentation. FEBS Letters, 361(2â3), 135â139. Portico.

Authors 2

Harry Walter (first)
Donald E. Brooks (additional)

References 40 Referenced 193

H. Walter D.E. Brooks D. Fisher 1985 Academic Press Orlando FL
P.-Å. Albertsson 1986 Wiley-Interscience New York NY
{'key': 'e_1_2_1_4_1', 'volume': '228', 'author': 'Walter H.', 'year': '1994', 'journal-title': 'Methods Enzymol.'} / Methods Enzymol. by Walter H. (1994)
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D.P. Jones 1988 CRC Press Boca Raton FL
G.R. Welch J.S. Clegg 1986 Plenum Press New York
{'key': 'e_1_2_1_12_1', 'first-page': '211', 'volume-title': 'Biological Polyelectrolytes', 'author': 'Veis A.', 'year': '1970'} / Biological Polyelectrolytes by Veis A. (1970)
A.I. Oparin 1953 Dover Publications New York NY
10.1016/S0268-005X(88)80001-8
10.1016/S0268-005X(09)80196-3
10.1016/0006-291X(80)90763-9
K.E. Van Holde 1985 Prentice-Hall Englewood Cliffs NJ
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10.1016/S0006-3495(92)81663-6
10.1016/0005-2736(86)90526-2
{'key': 'e_1_2_1_21_1', 'first-page': '1011', 'volume-title': 'Proc. Natl. Acad. Sci. USA', 'author': 'Kellermayer M.', 'year': '1986'} / Proc. Natl. Acad. Sci. USA by Kellermayer M. (1986)
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{'key': 'e_1_2_1_25_1', 'first-page': '267', 'volume-title': 'Partitioning in Aqueous Two-Phase Systems: Theory, Methods, Uses, and Applications to Biotechnology', 'author': 'Backman L.', 'year': '1985'} / Partitioning in Aqueous Two-Phase Systems: Theory, Methods, Uses, and Applications to Biotechnology by Backman L. (1985)
10.1016/S0022-5193(05)80511-9
10.1242/jcs.106.2.565
{'key': 'e_1_2_1_28_1', 'first-page': '5030', 'volume-title': 'Proc. Natl. Acad. Sci. USA', 'author': 'Gershon N.D.', 'year': '1984'} / Proc. Natl. Acad. Sci. USA by Gershon N.D. (1984)
{'key': 'e_1_2_1_29_1', 'first-page': 'S1', 'author': 'Rorschach H.E.', 'year': '1991', 'journal-title': 'Scanning Microscopy'} / Scanning Microscopy by Rorschach H.E. (1991)
10.1152/ajpgi.1992.263.5.G733
{'key': 'e_1_2_1_31_1', 'first-page': '3414', 'volume-title': 'Proc. Natl. Acad. Sci. USA', 'author': 'Mastro A.M.', 'year': '1984'} / Proc. Natl. Acad. Sci. USA by Mastro A.M. (1984)
{'key': 'e_1_2_1_32_1', 'first-page': '6747', 'volume-title': 'Proc. Natl. Acad. Sci. USA', 'author': 'Jacobson K.', 'year': '1984'} / Proc. Natl. Acad. Sci. USA by Jacobson K. (1984)
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10.1016/0012-1606(63)90105-2
10.1042/bj1090569
10.1016/B978-0-12-222250-4.50014-3

Dates

Type	When
Created	22 years, 3 months ago (April 30, 2003, 6:24 p.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 8:02 a.m.)
Indexed	3 weeks, 4 days ago (July 30, 2025, 10:44 a.m.)
Issued	30 years, 5 months ago (March 20, 1995)
Published	30 years, 5 months ago (March 20, 1995)
Published Online	25 years, 5 months ago (March 7, 2000)
Published Print	30 years, 5 months ago (March 20, 1995)

Funders 0

None

BibTeX

@article{Walter_1995, title={Phase separation in cytoplasm, due to macromolecular crowding, is the basis for microcompartmentation}, volume={361}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(95)00159-7}, DOI={10.1016/0014-5793(95)00159-7}, number={2–3}, journal={FEBS Letters}, publisher={Wiley}, author={Walter, Harry and Brooks, Donald E.}, year={1995}, month=mar, pages={135–139} }

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