DOI: 10.1016/0014-5793(94)80428-1. <i>YGE1</i> is a yeast homologue of <i>Escherichia coli grpE</i> and is required for maintenance of mitochondrial functions

YGE1 is a yeast homologue of Escherichia coli grpE and is required for maintenance of mitochondrial functions

10.1016/0014-5793(94)80428-1

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

The grpE gene is a heat shock gene of Escherichia coli whose product functions as a chaperone to (re)fold proteins. We found a yeast homologue of grpE and designated it YGE1. YGE1 can replace grpE in E coli, indicating that YGE1 is a functional homologue of grpE. Deletion of YGE1 is lethal. During depletion of the Ygel product, mitochondria are sequestered in mother cells thereby accumulating cells without mitochondria, suggesting that Ygel protein plays a pivotal role in maintaining mitochondrial functions.

Bibliography

Ikeda, E., Yoshida, S., Mitsuzawa, H., Uno, I., & Toh-e, A. (1994). YGE1 is a yeast homologue of Escherichia coli grpE and is required for maintenance of mitochondrial functions. FEBS Letters, 339(3), 265â268. Portico.

Authors 5

Eri Ikeda (first)
Satoshi Yoshida (additional)
Hiroshi Mitsuzawa (additional)
Isao Uno (additional)
Akio Toh-e (additional)

References 27 Referenced 77

10.1016/0022-2836(77)90038-9
10.1101/gad.6.7.1165
10.1038/356683a0
10.1073/pnas.88.7.2874
10.1128/MCB.4.8.1454
10.1016/0092-8674(84)90279-4
10.1128/MCB.5.12.3517
10.1073/pnas.84.12.4156
10.1128/MCB.7.7.2568
10.1016/0092-8674(89)90058-5
10.1016/0092-8674(89)90059-7
10.1007/BF00280382
10.1016/0378-1119(93)90514-4
10.1083/jcb.109.6.2665
10.1038/349627a0
10.1083/jcb.114.4.609
10.1128/MCB.12.1.283
10.1083/jcb.114.4.623
10.1016/S0092-8674(05)80063-7
10.1128/jb.167.1.25-29.1986
1989 Cold Spring Harbor Laboratory Press Cold Spring Harbor New York J. Sambrook E.F. Fritsch T. Maniatis Molecular Cloning: A Laboratory mannual
10.1073/pnas.74.12.5463
10.1083/jcb.88.3.526
10.1093/nar/16.15.7545
10.1128/MCB.13.5.3076
10.1002/yea.320090205
10.1038/332800a0

Dates

Type	When
Created	23 years ago (July 25, 2002, 3:40 a.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 3:23 p.m.)
Indexed	1 month, 3 weeks ago (June 27, 2025, 6:34 a.m.)
Issued	31 years, 6 months ago (Feb. 21, 1994)
Published	31 years, 6 months ago (Feb. 21, 1994)
Published Online	23 years, 9 months ago (Nov. 5, 2001)
Published Print	31 years, 6 months ago (Feb. 21, 1994)

Funders 0

None

BibTeX

@article{Ikeda_1994, title={YGE1 is a yeast homologue of Escherichia coli grpE and is required for maintenance of mitochondrial functions}, volume={339}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(94)80428-1}, DOI={10.1016/0014-5793(94)80428-1}, number={3}, journal={FEBS Letters}, publisher={Wiley}, author={Ikeda, Eri and Yoshida, Satoshi and Mitsuzawa, Hiroshi and Uno, Isao and Toh-e, Akio}, year={1994}, month=feb, pages={265–268} }

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