DOI: 10.1016/0014-5793(94)00656-3. The human ubiquitin‐conjugating enzyme UbcH1 is involved in the repair of UV‐damaged, alkylated and cross‐linked DNA

The human ubiquitin‐conjugating enzyme UbcH1 is involved in the repair of UV‐damaged, alkylated and cross‐linked DNA

10.1016/0014-5793(94)00656-3

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

The human ubiquitin‐conjugating enzyme UbcH1 shows 69% identity to the Saccharomyces cerevisiae RAD6/UBC2 which plays a key role in DNA repair. To examine the function of UbcH1 (formerly named E2, M, 17 000), [(1990) EMBO J. 9, 1431–1435]) we tested its ability to functionally substitute for yeast RAD6/UBC2 in the recovery of cells from various DNA damage. Complementation by expression of the human UbcH1 cDNA revealed that the UbcH1 carries out the function of S. cerevisiae RAD6/UBC2 in the repair of UV‐damaged, alkylated and cross‐linked DNA.

Bibliography

Kaiser, P., Mansourl, H. A., Greeten, T., Auer, B., Schweiger, M., & Schneider, R. (1994). The human ubiquitinâconjugating enzyme UbcH1 is involved in the repair of UVâdamaged, alkylated and crossâlinked DNA. FEBS Letters, 350(1), 1â4. Portico.

Authors 6

Peter Kaiser (first)
Hamdy A. Mansourl (additional)
Tim Greeten (additional)
Bernhard Auer (additional)
Manfred Schweiger (additional)
Rainer Schneider (additional)

References 31 Referenced 13

10.1146/annurev.ge.26.120192.001143
10.1146/annurev.bi.61.070192.003553
10.1146/annurev.cb.07.110191.000325
10.1007/978-1-4899-2049-2
10.1038/329131a0
1981 Cold Spring Harbor Laboratory New York J.N. Strathern E.W. Jones J.R. Broach The Molecular Biology of the Yeast Saccharomyces Lif Cycle and Inheritance
10.1073/pnas.88.16.7351
10.1016/0092-8674(92)90285-K
10.1101/gad.2.11.1476
10.1002/j.1460-2075.1990.tb08258.x
10.1073/pnas.88.9.3832
10.1016/S0021-9258(18)54365-9
10.1016/S0021-9258(19)50455-0
10.1002/j.1460-2075.1990.tb08259.x
10.1073/pnas.88.20.8865
10.1016/S0021-9258(17)37039-4
10.1128/jb.153.1.163-168.1983
10.1007/BF00280001
10.1002/yea.320020304
{'key': 'e_1_2_1_21_1', 'first-page': '522', 'volume': '14', 'author': 'Berghammer H.', 'year': '1993', 'journal-title': 'Biotechniques'} / Biotechniques by Berghammer H. (1993)
1989 Cold Spring Harbor Laboratory Press Cold Spring Harbor J. Sambrook E.F. Fritsch T. Maniatis Molecular Cloning: A Laboratory Manual
10.1093/nar/19.20.5791
{'key': 'e_1_2_1_24_1', 'first-page': '552', 'volume': '14', 'author': 'Kaiser P.', 'year': '1993', 'journal-title': 'Biotechniques'} / Biotechniques by Kaiser P. (1993)
10.1016/0076-6879(83)01014-9
10.1002/bies.950150405
10.1002/bies.950130607
10.1002/j.1460-2075.1993.tb05859.x
10.1128/mr.52.1.70-102.1988
1985 Freeman New York E.C. Friedberg DNA Repair
10.1002/j.1460-2075.1992.tb05380.x
10.1128/MCB.8.3.1179

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:40 a.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 5:46 a.m.)
Indexed	1 year, 1 month ago (July 10, 2024, 2:31 a.m.)
Issued	31 years ago (Aug. 15, 1994)
Published	31 years ago (Aug. 15, 1994)
Published Online	23 years, 10 months ago (Oct. 19, 2001)
Published Print	31 years ago (Aug. 15, 1994)

Funders 0

None

BibTeX

@article{Kaiser_1994, title={The human ubiquitin‐conjugating enzyme UbcH1 is involved in the repair of UV‐damaged, alkylated and cross‐linked DNA}, volume={350}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(94)00656-3}, DOI={10.1016/0014-5793(94)00656-3}, number={1}, journal={FEBS Letters}, publisher={Wiley}, author={Kaiser, Peter and Mansourl, Hamdy A. and Greeten, Tim and Auer, Bernhard and Schweiger, Manfred and Schneider, Rainer}, year={1994}, month=aug, pages={1–4} }

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