DOI: 10.1016/0014-5793(93)80262-s. Cloning and expression of a novel human profilin variant, profilin II

Cloning and expression of a novel human profilin variant, profilin II

10.1016/0014-5793(93)80262-s

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

We have isolated a 1.7 kbp cDNA encoding a 140 amino acid protein (15.1 kDa, pI 5.91) with a high sequence similarity (62%) to human profilin (profilin I). We have termed this variant profilin II. Northern blot analysis showed that profilin II is highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver. In addition, three different transcript lengths were detected. Only one transcript of profilin I was found. The expression level of this was low in brain and skeletal muscle, medium in heart and high in placenta, lung, liver and kidney.

Bibliography

HonorÃ©, B., Madsen, P., Andersen, A. H., & Leffers, H. (1993). Cloning and expression of a novel human profilin variant, profilin II. FEBS Letters, 330(2), 151â155. Portico.

Authors 4

Bent Honoré (first)
Peder Madsen (additional)
Annette H. Andersen (additional)
Henrik Leffers (additional)

References 34 Referenced 66

10.1016/0022-2836(76)90098-X
10.1016/0014-5793(78)80610-3
10.1016/0014-5793(78)80303-2
10.1111/j.1432-1033.1980.tb04517.x
10.1016/0014-5793(80)80227-4
10.1016/S0021-9258(17)39622-9
10.1016/S0021-9258(18)60651-9
10.1016/0022-2836(77)90166-8
10.1016/0092-8674(81)90002-7
10.1016/0968-0004(92)90016-3
10.1126/science.2157283
10.1016/0092-8674(81)90013-1
{'key': 'e_1_2_1_14_1', 'volume-title': 'Molecular Cloning: A Laboratory Manual', 'author': 'Sambrook J.', 'year': '1989'} / Molecular Cloning: A Laboratory Manual by Sambrook J. (1989)
10.1093/nar/16.6.2726
10.1073/pnas.74.12.5463
10.1016/0076-6879(90)83014-Z
10.1093/nar/12.1Part1.387
10.1002/prot.340070310
10.1016/S0021-9258(18)42471-4
10.1016/0014-5793(89)80009-2
10.1093/nar/17.7.2855
10.1016/0014-5793(88)80575-1
10.1016/S0021-9258(20)71174-9
10.1111/j.1432-1033.1988.tb13739.x
10.1073/pnas.79.19.5901
10.1093/nar/11.11.3503
10.1093/nar/17.4.1767
10.1073/pnas.82.18.6133
10.1128/MCB.8.4.1775
10.1093/nar/18.14.4263
10.1038/359244a0
10.1038/359246a0
10.1083/jcb.102.1.221
10.1091/mbc.1.12.937

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:41 a.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 10:17 p.m.)
Indexed	3 months, 3 weeks ago (May 7, 2025, 3:34 a.m.)
Issued	31 years, 11 months ago (Sept. 13, 1993)
Published	31 years, 11 months ago (Sept. 13, 1993)
Published Online	23 years, 10 months ago (Oct. 29, 2001)
Published Print	31 years, 11 months ago (Sept. 13, 1993)

Funders 0

None

BibTeX

@article{Honor__1993, title={Cloning and expression of a novel human profilin variant, profilin II}, volume={330}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(93)80262-s}, DOI={10.1016/0014-5793(93)80262-s}, number={2}, journal={FEBS Letters}, publisher={Wiley}, author={Honoré, Bent and Madsen, Peder and Andersen, Annette H. and Leffers, Henrik}, year={1993}, month=sep, pages={151–155} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        5,
        7
      ]
    ],
    "date-time": "2025-05-07T07:34:01Z",
    "timestamp": 1746603241683
  },
  "reference-count": 34,
  "publisher": "Wiley",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2001,
            10,
            29
          ]
        ],
        "date-time": "2001-10-29T00:00:00Z",
        "timestamp": 1004313600000
      },
      "content-version": "vor",
      "delay-in-days": 2968,
      "URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1993,
        9,
        13
      ]
    ]
  },
  "abstract": "<jats:p>We have isolated a 1.7 kbp cDNA encoding a 140 amino acid protein (15.1 kDa, pI 5.91) with a high sequence similarity (62%) to human profilin (profilin I). We have termed this variant profilin II. Northern blot analysis showed that profilin II is highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver. In addition, three different transcript lengths were detected. Only one transcript of profilin I was found. The expression level of this was low in brain and skeletal muscle, medium in heart and high in placenta, lung, liver and kidney.</jats:p>",
  "DOI": "10.1016/0014-5793(93)80262-s",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T07:41:36Z",
    "timestamp": 1027582896000
  },
  "page": "151-155",
  "source": "Crossref",
  "is-referenced-by-count": 66,
  "title": "Cloning and expression of a novel human profilin variant, profilin II",
  "prefix": "10.1002",
  "volume": "330",
  "author": [
    {
      "given": "Bent",
      "family": "Honor\u00e9",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Peder",
      "family": "Madsen",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Annette H.",
      "family": "Andersen",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Henrik",
      "family": "Leffers",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "311",
  "published-online": {
    "date-parts": [
      [
        2001,
        10,
        29
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_2_1_2_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0022-2836(76)90098-X"
    },
    {
      "key": "e_1_2_1_3_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0014-5793(78)80610-3"
    },
    {
      "key": "e_1_2_1_4_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0014-5793(78)80303-2"
    },
    {
      "key": "e_1_2_1_5_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1432-1033.1980.tb04517.x"
    },
    {
      "key": "e_1_2_1_6_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0014-5793(80)80227-4"
    },
    {
      "key": "e_1_2_1_7_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(17)39622-9"
    },
    {
      "key": "e_1_2_1_8_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(18)60651-9"
    },
    {
      "key": "e_1_2_1_9_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0022-2836(77)90166-8"
    },
    {
      "key": "e_1_2_1_10_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(81)90002-7"
    },
    {
      "key": "e_1_2_1_11_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0968-0004(92)90016-3"
    },
    {
      "key": "e_1_2_1_12_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.2157283"
    },
    {
      "key": "e_1_2_1_13_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(81)90013-1"
    },
    {
      "key": "e_1_2_1_14_1",
      "volume-title": "Molecular Cloning: A Laboratory Manual",
      "author": "Sambrook J.",
      "year": "1989"
    },
    {
      "key": "e_1_2_1_15_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/nar/16.6.2726"
    },
    {
      "key": "e_1_2_1_16_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.74.12.5463"
    },
    {
      "key": "e_1_2_1_17_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0076-6879(90)83014-Z"
    },
    {
      "key": "e_1_2_1_18_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/nar/12.1Part1.387"
    },
    {
      "key": "e_1_2_1_19_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/prot.340070310"
    },
    {
      "key": "e_1_2_1_20_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(18)42471-4"
    },
    {
      "key": "e_1_2_1_21_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0014-5793(89)80009-2"
    },
    {
      "key": "e_1_2_1_22_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/nar/17.7.2855"
    },
    {
      "key": "e_1_2_1_23_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0014-5793(88)80575-1"
    },
    {
      "key": "e_1_2_1_24_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(20)71174-9"
    },
    {
      "key": "e_1_2_1_25_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1432-1033.1988.tb13739.x"
    },
    {
      "key": "e_1_2_1_26_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.79.19.5901"
    },
    {
      "key": "e_1_2_1_27_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/nar/11.11.3503"
    },
    {
      "key": "e_1_2_1_28_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/nar/17.4.1767"
    },
    {
      "key": "e_1_2_1_29_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.82.18.6133"
    },
    {
      "key": "e_1_2_1_30_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1128/MCB.8.4.1775"
    },
    {
      "key": "e_1_2_1_31_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/nar/18.14.4263"
    },
    {
      "key": "e_1_2_1_32_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/359244a0"
    },
    {
      "key": "e_1_2_1_33_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/359246a0"
    },
    {
      "key": "e_1_2_1_34_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1083/jcb.102.1.221"
    },
    {
      "key": "e_1_2_1_35_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1091/mbc.1.12.937"
    }
  ],
  "container-title": "FEBS Letters",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793%2893%2980262-S",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793(93)80262-S",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/0014-5793%2893%2980262-S",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        9,
        17
      ]
    ],
    "date-time": "2023-09-17T02:17:31Z",
    "timestamp": 1694917051000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://febs.onlinelibrary.wiley.com/doi/10.1016/0014-5793%2893%2980262-S"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1993,
        9,
        13
      ]
    ]
  },
  "references-count": 34,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1993,
          9,
          13
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1016/0014-5793(93)80262-S"
  ],
  "URL": "http://dx.doi.org/10.1016/0014-5793(93)80262-S",
  "relation": {},
  "ISSN": [
    "0014-5793",
    "1873-3468"
  ],
  "subject": [],
  "container-title-short": "FEBS Letters",
  "published": {
    "date-parts": [
      [
        1993,
        9,
        13
      ]
    ]
  }
}