DOI: 10.1016/0014-5793(90)80601-e. Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family

Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family

10.1016/0014-5793(90)80601-e

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

Two myotropic peptides termed locustatachykinin I (Gly‐Pro‐Ser‐Gly‐Phe‐Tyr‐Gly‐Val‐Arg‐NH2) and locustatachykinin II (Ala‐Pro‐Leu‐Ser‐Gly‐Phe‐Tyr‐Gly‐Val‐Arg‐NH2) were isolated from brain‐corpora cardiaca‐corpora allata‐suboesophageal ganglion extracts of the locust, Locusta migratoria. Both peptides exhibit sequence homologies with the vertebrate tachykinins. Sequence homology is greater with the fish and amphibian tachykinins (up to 45%) than with the mammalian tachykinins. In addition, the intestinal myotropic activity of the locustatachykinins is analogous to that of vertebrate tachykinins. The peptides discovered in this study may just be the first in a whole series of substances from arthropod species to be identified as tachykinin family peptides. Moreover, both chemical and biological similarities of vertebrate and insect tachykinins substantiate the evidence for a long evolutionary history of the tachykinin peptide family.

Bibliography

Schoofs, L., Holman, G. M., Hayes, T. K., Nachman, R. J., & De Loof, A. (1990). Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family. FEBS Letters, 261(2), 397â401. Portico.

Authors 5

Liliane Schoofs (first)
G.Mark Holman (additional)
Timothy K. Hayes (additional)
Ronald J. Nachman (additional)
Arnold De Loof (additional)

References 30 Referenced 197

10.1016/0016-6480(88)90292-4
10.1111/j.1570-7458.1987.tb01069.x
{'key': 'e_1_2_1_4_1', 'first-page': '514', 'volume': '78', 'author': 'Rémy C.', 'year': '1982', 'journal-title': 'J. Physiol. (Paris)'} / J. Physiol. (Paris) by Rémy C. (1982)
10.1007/BF00217150
10.1126/science.3749893
10.1016/0006-291X(86)91098-3
10.1126/science.226.4680.1344
10.1016/0020-1790(86)90113-7
10.1073/pnas.81.17.5575
10.1002/arch.940050302
10.1073/pnas.86.8.2976
10.1016/0167-0115(80)90271-2
10.1007/BF00214685
10.1007/BF00492539
10.1007/BF00213788
{'key': 'e_1_2_1_17_1', 'first-page': '501', 'volume': '83', 'author': 'Verhaert P.', 'year': '1985', 'journal-title': 'Biochemistry'} / Biochemistry by Verhaert P. (1985)
10.1007/BF00222342
10.1016/0020-1790(88)90101-1
{'key': 'e_1_2_1_20_1', 'first-page': '582', 'volume-title': 'The UFAW Handbook on the Care and Management of Laboratory Animals', 'author': 'Ashby G.J.', 'year': '1972'} / The UFAW Handbook on the Care and Management of Laboratory Animals by Ashby G.J. (1972)
10.1016/0306-4492(78)90057-6
{'key': 'e_1_2_1_22_1', 'first-page': '205', 'volume': '84', 'author': 'Holman G.M.', 'year': '1986', 'journal-title': 'Comp. Biochem. Physiol.'} / Comp. Biochem. Physiol. by Holman G.M. (1986)
10.1016/S0076-6879(83)91038-8
10.1016/0166-2236(81)90084-9
10.1016/0167-0115(88)90244-3
10.1016/0014-5793(86)80521-X
10.1016/0166-2236(86)90014-7
10.1016/0003-9861(63)90533-2
10.1007/BF01968266
10.1016/0167-0115(88)90241-8
10.1038/306032a0

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:45 a.m.)
Deposited	1 year, 11 months ago (Sept. 15, 2023, 9:17 p.m.)
Indexed	1 month ago (Aug. 5, 2025, 9:09 a.m.)
Issued	35 years, 6 months ago (Feb. 26, 1990)
Published	35 years, 6 months ago (Feb. 26, 1990)
Published Online	23 years, 9 months ago (Nov. 14, 2001)
Published Print	35 years, 6 months ago (Feb. 26, 1990)

Funders 0

None

BibTeX

@article{Schoofs_1990, title={Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family}, volume={261}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(90)80601-e}, DOI={10.1016/0014-5793(90)80601-e}, number={2}, journal={FEBS Letters}, publisher={Wiley}, author={Schoofs, Liliane and Holman, G.Mark and Hayes, Timothy K. and Nachman, Ronald J. and De Loof, Arnold}, year={1990}, month=feb, pages={397–401} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        5
      ]
    ],
    "date-time": "2025-08-05T13:09:55Z",
    "timestamp": 1754399395176
  },
  "reference-count": 30,
  "publisher": "Wiley",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2001,
            11,
            14
          ]
        ],
        "date-time": "2001-11-14T00:00:00Z",
        "timestamp": 1005696000000
      },
      "content-version": "vor",
      "delay-in-days": 4279,
      "URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1990,
        2,
        26
      ]
    ]
  },
  "abstract": "<jats:p>Two myotropic peptides termed locustatachykinin I (Gly\u2010Pro\u2010Ser\u2010Gly\u2010Phe\u2010Tyr\u2010Gly\u2010Val\u2010Arg\u2010NH<jats:sub>2</jats:sub>) and locustatachykinin II (Ala\u2010Pro\u2010Leu\u2010Ser\u2010Gly\u2010Phe\u2010Tyr\u2010Gly\u2010Val\u2010Arg\u2010NH<jats:sub>2</jats:sub>) were isolated from brain\u2010corpora cardiaca\u2010corpora allata\u2010suboesophageal ganglion extracts of the locust, <jats:sub>Locusta migratoria</jats:sub>. Both peptides exhibit sequence homologies with the vertebrate tachykinins. Sequence homology is greater with the fish and amphibian tachykinins (up to 45%) than with the mammalian tachykinins. In addition, the intestinal myotropic activity of the locustatachykinins is analogous to that of vertebrate tachykinins. The peptides discovered in this study may just be the first in a whole series of substances from arthropod species to be identified as tachykinin family peptides. Moreover, both chemical and biological similarities of vertebrate and insect tachykinins substantiate the evidence for a long evolutionary history of the tachykinin peptide family.</jats:p>",
  "DOI": "10.1016/0014-5793(90)80601-e",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T07:45:01Z",
    "timestamp": 1027583101000
  },
  "page": "397-401",
  "source": "Crossref",
  "is-referenced-by-count": 197,
  "title": "Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family",
  "prefix": "10.1002",
  "volume": "261",
  "author": [
    {
      "given": "Liliane",
      "family": "Schoofs",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "G.Mark",
      "family": "Holman",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Timothy K.",
      "family": "Hayes",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Ronald J.",
      "family": "Nachman",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Arnold",
      "family": "De Loof",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "311",
  "published-online": {
    "date-parts": [
      [
        2001,
        11,
        14
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_2_1_2_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0016-6480(88)90292-4"
    },
    {
      "key": "e_1_2_1_3_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1570-7458.1987.tb01069.x"
    },
    {
      "key": "e_1_2_1_4_1",
      "first-page": "514",
      "volume": "78",
      "author": "R&#x00E9;my C.",
      "year": "1982",
      "journal-title": "J. Physiol. (Paris)"
    },
    {
      "key": "e_1_2_1_5_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00217150"
    },
    {
      "key": "e_1_2_1_6_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.3749893"
    },
    {
      "key": "e_1_2_1_7_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0006-291X(86)91098-3"
    },
    {
      "key": "e_1_2_1_8_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.226.4680.1344"
    },
    {
      "key": "e_1_2_1_9_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0020-1790(86)90113-7"
    },
    {
      "key": "e_1_2_1_10_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.81.17.5575"
    },
    {
      "key": "e_1_2_1_11_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/arch.940050302"
    },
    {
      "key": "e_1_2_1_12_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.86.8.2976"
    },
    {
      "key": "e_1_2_1_13_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0167-0115(80)90271-2"
    },
    {
      "key": "e_1_2_1_14_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00214685"
    },
    {
      "key": "e_1_2_1_15_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00492539"
    },
    {
      "key": "e_1_2_1_16_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00213788"
    },
    {
      "key": "e_1_2_1_17_1",
      "first-page": "501",
      "volume": "83",
      "author": "Verhaert P.",
      "year": "1985",
      "journal-title": "Biochemistry"
    },
    {
      "key": "e_1_2_1_18_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF00222342"
    },
    {
      "key": "e_1_2_1_19_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0020-1790(88)90101-1"
    },
    {
      "key": "e_1_2_1_20_1",
      "first-page": "582",
      "volume-title": "The UFAW Handbook on the Care and Management of Laboratory Animals",
      "author": "Ashby G.J.",
      "year": "1972"
    },
    {
      "key": "e_1_2_1_21_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0306-4492(78)90057-6"
    },
    {
      "key": "e_1_2_1_22_1",
      "first-page": "205",
      "volume": "84",
      "author": "Holman G.M.",
      "year": "1986",
      "journal-title": "Comp. Biochem. Physiol."
    },
    {
      "key": "e_1_2_1_23_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0076-6879(83)91038-8"
    },
    {
      "key": "e_1_2_1_24_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0166-2236(81)90084-9"
    },
    {
      "key": "e_1_2_1_25_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0167-0115(88)90244-3"
    },
    {
      "key": "e_1_2_1_26_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0014-5793(86)80521-X"
    },
    {
      "key": "e_1_2_1_27_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0166-2236(86)90014-7"
    },
    {
      "key": "e_1_2_1_28_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0003-9861(63)90533-2"
    },
    {
      "key": "e_1_2_1_29_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF01968266"
    },
    {
      "key": "e_1_2_1_30_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0167-0115(88)90241-8"
    },
    {
      "key": "e_1_2_1_31_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/306032a0"
    }
  ],
  "container-title": "FEBS Letters",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793%2890%2980601-E",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793(90)80601-E",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/0014-5793%2890%2980601-E",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        9,
        16
      ]
    ],
    "date-time": "2023-09-16T01:17:50Z",
    "timestamp": 1694827070000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://febs.onlinelibrary.wiley.com/doi/10.1016/0014-5793%2890%2980601-E"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1990,
        2,
        26
      ]
    ]
  },
  "references-count": 30,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1990,
          2,
          26
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1016/0014-5793(90)80601-E"
  ],
  "URL": "http://dx.doi.org/10.1016/0014-5793(90)80601-E",
  "relation": {},
  "ISSN": [
    "0014-5793",
    "1873-3468"
  ],
  "subject": [],
  "container-title-short": "FEBS Letters",
  "published": {
    "date-parts": [
      [
        1990,
        2,
        26
      ]
    ]
  }
}