DOI: 10.1016/0014-5793(88)80378-8. Two isoforms of protein phosphatase 1 may be produced from the same gene

Two isoforms of protein phosphatase 1 may be produced from the same gene

10.1016/0014-5793(88)80378-8

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

A cDNA clone encoding a second type‐1 protein phosphatase catalytic subunit (1α) was isolated from a rabbit skeletal muscle cDNA library constructed in λgt10. The deduced protein sequence (330 residues, 37.5 kDa) was 19 residues longer at its N‐terminus than protein phosphatase 1β (311 residues, 35.4 kDa). The amino acid sequences of protein phosphatases 1α and 1β were identical after residue 33 of protein phosphatase 1α. The results suggest that the different N‐terminal sequences of protein phosphatases 1α and 1β are likely to be generated by differential transcription or processing of the mRNA transcribed from a single gene. Southern blotting of rabbit DNA was consistent with this interpretation.

Bibliography

Cohen, P. T. W. (1988). Two isoforms of protein phosphatase 1 may be produced from the same gene. FEBS Letters, 232(1), 17â23. Portico.

Authors 1

Patricia T.W. Cohen (first)

References 29 Referenced 89

10.1111/j.1432-1033.1985.tb09121.x
1987 L.M. Ballou E.H. Fischer P.D. Boyer E.G. Krebs The Enzymes 312 361
10.1111/j.1432-1033.1983.tb07357.x
10.1016/0014-5793(87)80316-2
10.1016/0014-5793(87)80966-3
10.1016/0014-5793(87)80574-4
10.1016/0014-5793(87)80871-2
1987 P.T.W. Cohen N. Berndt Cruz e Silva O.B. Da D.G. Campbell V. Zappia 1st International Meeting on Post-translational Modifications of Proteins and Ageing Ischia Italy May 1987 549 557 (10.1007/978-1-4684-9042-8_46)
10.1016/0378-1119(83)90039-2
10.1073/pnas.74.12.5463
10.1073/pnas.80.13.3963
10.1093/nar/14.3.1319
10.1093/nar/3.9.2303
10.1016/0003-2697(83)90418-9
10.1093/nar/12.2.857
10.1038/2231270a0
10.1111/j.1432-1033.1970.tb01132.x
10.1111/j.1432-1033.1976.tb10524.x
10.1038/308333a0
10.1002/j.1460-2075.1985.tb03972.x
10.1038/326707a0
10.1021/bi00396a007
10.1016/0014-5793(82)80760-6
10.1021/bi00283a014
10.1111/j.1432-1033.1984.tb08521.x
10.1111/j.1432-1033.1985.tb08926.x
10.1111/j.1432-1033.1987.tb10795.x
{'key': 'e_1_2_1_29_1', 'author': 'Chisholm A.K.', 'year': '1988', 'journal-title': 'Biochim. Biophys. Acta'} / Biochim. Biophys. Acta by Chisholm A.K. (1988)
10.1210/mend-1-10-745

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:45 a.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 11:03 p.m.)
Indexed	3 weeks, 4 days ago (Aug. 5, 2025, 9:08 a.m.)
Issued	37 years, 3 months ago (May 9, 1988)
Published	37 years, 3 months ago (May 9, 1988)
Published Online	23 years, 10 months ago (Oct. 19, 2001)
Published Print	37 years, 3 months ago (May 9, 1988)

Funders 0

None

BibTeX

@article{Cohen_1988, title={Two isoforms of protein phosphatase 1 may be produced from the same gene}, volume={232}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(88)80378-8}, DOI={10.1016/0014-5793(88)80378-8}, number={1}, journal={FEBS Letters}, publisher={Wiley}, author={Cohen, Patricia T.W.}, year={1988}, month=may, pages={17–23} }

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