DOI: 10.1016/0014-5793(88)80224-2. Mechanistic studies on the phosphorylation of photoexcited rhodopsin

Mechanistic studies on the phosphorylation of photoexcited rhodopsin

10.1016/0014-5793(88)80224-2

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

The mechanism of the photophosphorylation of rhodopsin was studied using several synthetic peptides corresponding to the sequence of the phosphorylation domain. It was found that the decapeptide (residues 339–348) was effectively phosphorylated by rhodopsin kinase only when incubation was performed in the presence of both rhodopsin and light. These results are interpreted to suggest that in the dark‐adapted state rhodopsin kinase exists in an inactive conformation and that this is converted into a catalytically competent form only after interaction with metarhodopsin II (Rho*)

Bibliography

Fowles, C., Sharma, R., & Akhtar, M. (1988). Mechanistic studies on the phosphorylation of photoexcited rhodopsin. FEBS Letters, 238(1), 56â60. Portico.

Authors 3

Charles Fowles (first)
Ram Sharma (additional)
M. Akhtar (additional)

References 18 Referenced 93

{'key': 'e_1_2_1_2_1', 'first-page': '123', 'volume-title': 'Progress in Retinal Research', 'author': 'Kühn H.', 'year': '1984'} / Progress in Retinal Research by Kühn H. (1984)
10.1073/pnas.78.1.152
10.1073/pnas.74.10.4238
10.1038/334016a0
10.1016/0014-5793(72)80002-4
10.1038/newbio237125a0
10.1042/bj1750421
10.1021/bi00541a032
10.1042/bj2200773
10.1038/287734a0
10.1073/pnas.83.5.1174
10.1021/bi00366a002
10.1042/bj2460131
10.1021/bi00644a040
{'key': 'e_1_2_1_16_1', 'first-page': '490', 'volume': '81', 'author': 'Kühn H.', 'year': '1982', 'journal-title': 'Methods Enzymol.'} / Methods Enzymol. by Kühn H. (1982)
10.1016/0014-5793(82)80805-3
{'key': 'e_1_2_1_18_1', 'first-page': '5455', 'volume': '29', 'author': 'Lu G.-S.', 'year': '1987', 'journal-title': 'Int. J. Peptide Protein Res.'} / Int. J. Peptide Protein Res. by Lu G.-S. (1987)
10.1021/bi00407a010

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:45 a.m.)
Deposited	1 year, 11 months ago (Sept. 17, 2023, 2:59 a.m.)
Indexed	1 year, 9 months ago (Nov. 23, 2023, 12:24 a.m.)
Issued	36 years, 11 months ago (Sept. 26, 1988)
Published	36 years, 11 months ago (Sept. 26, 1988)
Published Online	23 years, 10 months ago (Oct. 19, 2001)
Published Print	36 years, 11 months ago (Sept. 26, 1988)

Funders 0

None

BibTeX

@article{Fowles_1988, title={Mechanistic studies on the phosphorylation of photoexcited rhodopsin}, volume={238}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(88)80224-2}, DOI={10.1016/0014-5793(88)80224-2}, number={1}, journal={FEBS Letters}, publisher={Wiley}, author={Fowles, Charles and Sharma, Ram and Akhtar, M.}, year={1988}, month=sep, pages={56–60} }

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