DOI: 10.1016/0014-5793(87)81199-7. Kinetics of association and dissociation of colchicine‐tubulin complex from brain and renal tubulin Evidence for the existence of multiple isotypes of tubulin in brain with differential affinity to colchicine

Kinetics of association and dissociation of colchicine‐tubulin complex from brain and renal tubulin Evidence for the existence of multiple isotypes of tubulin in brain with differential affinity to colchicine

10.1016/0014-5793(87)81199-7

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

The kinetics of colchicine binding to bovine brain tubulin have been reported to be biphasic under pseudo first order conditions [(1978) Biochemistry 17, 4466‐4472]. Unlike brain tubulin, the kinetics of colchicine binding to bovine renal tubulin are monophasic. The apparent on‐rate constant for the binding of colchicine to renal tubulin is found to be very close to that of the faster binding component in brain tubulin. Similarly, the dissociation of colchicine‐tubulin complex in the presence of iodide is biphasic for brain tubulin but monophasic for renal tubulin. Since brain and renal tubulin apparently differ in β‐tubulin, our results suggest that the biphasic nature of the kinetics for bovine brain tubulin could possibly originate from the existence of multiple isotypes of tubulin differing in drug binding affinity.

Bibliography

Banerjee, A., & Luduena, R. F. (1987). Kinetics of association and dissociation of colchicineâtubulin complex from brain and renal tubulin Evidence for the existence of multiple isotypes of tubulin in brain with differential affinity to colchicine. FEBS Letters, 219(1), 103â107. Portico.

Authors 2

Asok Banerjee (first)
Richard F. Luduena (additional)

References 32 Referenced 33

10.1021/bi00764a010
10.1016/0006-291X(72)90546-3
10.1146/annurev.bi.42.070173.002451
{'key': 'e_1_2_1_5_1', 'first-page': '21', 'volume': '3', 'author': 'Wilson L.', 'year': '1974', 'journal-title': 'Adv. Cell. Mol. Biol.'} / Adv. Cell. Mol. Biol. by Wilson L. (1974)
10.1007/978-3-642-96436-7
10.1016/S0021-9258(17)40631-4
10.1021/bi00613a024
10.1016/S0021-9258(19)69603-1
10.1021/bi00524a012
10.1073/pnas.71.7.2627
10.1021/bi00532a019
10.1038/276411a0
10.1016/0006-291X(79)91786-8
10.1111/j.1471-4159.1979.tb00374.x
10.1021/bi00512a006
10.1111/j.1471-4159.1984.tb02796.x
10.1073/pnas.81.13.4041
10.1073/pnas.78.5.2757
10.1016/0014-5793(79)81229-6
10.1021/bi00262a041
10.1128/MCB.3.5.854
10.1083/jcb.101.3.852
10.1128/MCB.6.7.2409
10.1073/pnas.83.12.4327
10.1016/S0021-9258(18)69306-8
10.1083/jcb.104.3.381
10.1016/S0021-9258(19)68460-7
10.1111/j.1432-1033.1977.tb11726.x
10.1016/0003-9861(79)90303-5
10.1016/S0021-9258(19)52451-6
10.1007/978-1-4615-7658-7
10.1016/0003-2697(72)90046-2

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:57 a.m.)
Deposited	1 year, 11 months ago (Sept. 17, 2023, 1:32 a.m.)
Indexed	1 year, 1 month ago (Aug. 4, 2024, 6:35 a.m.)
Issued	38 years, 1 month ago (July 13, 1987)
Published	38 years, 1 month ago (July 13, 1987)
Published Online	23 years, 10 months ago (Oct. 19, 2001)
Published Print	38 years, 1 month ago (July 13, 1987)

Funders 0

None

BibTeX

@article{Banerjee_1987, title={Kinetics of association and dissociation of colchicine‐tubulin complex from brain and renal tubulin Evidence for the existence of multiple isotypes of tubulin in brain with differential affinity to colchicine}, volume={219}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(87)81199-7}, DOI={10.1016/0014-5793(87)81199-7}, number={1}, journal={FEBS Letters}, publisher={Wiley}, author={Banerjee, Asok and Luduena, Richard F.}, year={1987}, month=jul, pages={103–107} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        8,
        4
      ]
    ],
    "date-time": "2024-08-04T10:35:27Z",
    "timestamp": 1722767727218
  },
  "reference-count": 32,
  "publisher": "Wiley",
  "issue": "1",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2001,
            10,
            19
          ]
        ],
        "date-time": "2001-10-19T00:00:00Z",
        "timestamp": 1003449600000
      },
      "content-version": "vor",
      "delay-in-days": 5212,
      "URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1987,
        7,
        13
      ]
    ]
  },
  "abstract": "<jats:p>The kinetics of colchicine binding to bovine brain tubulin have been reported to be biphasic under pseudo first order conditions [(1978) Biochemistry 17, 4466\u20104472]. Unlike brain tubulin, the kinetics of colchicine binding to bovine renal tubulin are monophasic. The apparent on\u2010rate constant for the binding of colchicine to renal tubulin is found to be very close to that of the faster binding component in brain tubulin. Similarly, the dissociation of colchicine\u2010tubulin complex in the presence of iodide is biphasic for brain tubulin but monophasic for renal tubulin. Since brain and renal tubulin apparently differ in \u03b2\u2010tubulin, our results suggest that the biphasic nature of the kinetics for bovine brain tubulin could possibly originate from the existence of multiple isotypes of tubulin differing in drug binding affinity.</jats:p>",
  "DOI": "10.1016/0014-5793(87)81199-7",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T07:57:40Z",
    "timestamp": 1027583860000
  },
  "page": "103-107",
  "source": "Crossref",
  "is-referenced-by-count": 33,
  "title": "Kinetics of association and dissociation of colchicine\u2010tubulin complex from brain and renal tubulin Evidence for the existence of multiple isotypes of tubulin in brain with differential affinity to colchicine",
  "prefix": "10.1002",
  "volume": "219",
  "author": [
    {
      "given": "Asok",
      "family": "Banerjee",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Richard F.",
      "family": "Luduena",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "311",
  "published-online": {
    "date-parts": [
      [
        2001,
        10,
        19
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_2_1_2_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00764a010"
    },
    {
      "key": "e_1_2_1_3_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0006-291X(72)90546-3"
    },
    {
      "key": "e_1_2_1_4_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1146/annurev.bi.42.070173.002451"
    },
    {
      "key": "e_1_2_1_5_1",
      "first-page": "21",
      "volume": "3",
      "author": "Wilson L.",
      "year": "1974",
      "journal-title": "Adv. Cell. Mol. Biol."
    },
    {
      "key": "e_1_2_1_6_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/978-3-642-96436-7"
    },
    {
      "key": "e_1_2_1_7_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(17)40631-4"
    },
    {
      "key": "e_1_2_1_8_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00613a024"
    },
    {
      "key": "e_1_2_1_9_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(19)69603-1"
    },
    {
      "key": "e_1_2_1_10_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00524a012"
    },
    {
      "key": "e_1_2_1_11_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.71.7.2627"
    },
    {
      "key": "e_1_2_1_12_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00532a019"
    },
    {
      "key": "e_1_2_1_13_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/276411a0"
    },
    {
      "key": "e_1_2_1_14_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0006-291X(79)91786-8"
    },
    {
      "key": "e_1_2_1_15_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1471-4159.1979.tb00374.x"
    },
    {
      "key": "e_1_2_1_16_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00512a006"
    },
    {
      "key": "e_1_2_1_17_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1471-4159.1984.tb02796.x"
    },
    {
      "key": "e_1_2_1_18_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.81.13.4041"
    },
    {
      "key": "e_1_2_1_19_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.78.5.2757"
    },
    {
      "key": "e_1_2_1_20_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0014-5793(79)81229-6"
    },
    {
      "key": "e_1_2_1_21_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00262a041"
    },
    {
      "key": "e_1_2_1_22_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1128/MCB.3.5.854"
    },
    {
      "key": "e_1_2_1_23_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1083/jcb.101.3.852"
    },
    {
      "key": "e_1_2_1_24_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1128/MCB.6.7.2409"
    },
    {
      "key": "e_1_2_1_25_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.83.12.4327"
    },
    {
      "key": "e_1_2_1_26_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(18)69306-8"
    },
    {
      "key": "e_1_2_1_27_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1083/jcb.104.3.381"
    },
    {
      "key": "e_1_2_1_28_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(19)68460-7"
    },
    {
      "key": "e_1_2_1_29_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1432-1033.1977.tb11726.x"
    },
    {
      "key": "e_1_2_1_30_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0003-9861(79)90303-5"
    },
    {
      "key": "e_1_2_1_31_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0021-9258(19)52451-6"
    },
    {
      "key": "e_1_2_1_32_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/978-1-4615-7658-7"
    },
    {
      "key": "e_1_2_1_33_1",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0003-2697(72)90046-2"
    }
  ],
  "container-title": "FEBS Letters",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793%2887%2981199-7",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793(87)81199-7",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/0014-5793%2887%2981199-7",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        9,
        17
      ]
    ],
    "date-time": "2023-09-17T05:32:05Z",
    "timestamp": 1694928725000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://febs.onlinelibrary.wiley.com/doi/10.1016/0014-5793%2887%2981199-7"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1987,
        7,
        13
      ]
    ]
  },
  "references-count": 32,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          1987,
          7,
          13
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1016/0014-5793(87)81199-7"
  ],
  "URL": "http://dx.doi.org/10.1016/0014-5793(87)81199-7",
  "relation": {},
  "ISSN": [
    "0014-5793",
    "1873-3468"
  ],
  "subject": [],
  "container-title-short": "FEBS Letters",
  "published": {
    "date-parts": [
      [
        1987,
        7,
        13
      ]
    ]
  }
}