DOI: 10.1016/0014-5793(85)80702-x. <sup>1</sup>H‐NMR study of gramicidin A transmembrane ion channel

1H‐NMR study of gramicidin A transmembrane ion channel

10.1016/0014-5793(85)80702-x

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

The structure of[Val1]gramicidin A incorporated into sodium dodecyl‐d 25 sulphate micelles has been studied by two‐dimensional proton NMR spectroscopy. Analysis of nuclear Overhauser effects, spin‐spin couplings and solvent accessibility of NH groups show that the conformation of the Na+ complex of gramicidin A in detergent micelles, which in many ways mimic the phospholipid bilayer of biomembranes, is an N‐terminal to N‐terminal (head‐to‐head) dimer formed by two right‐handed, single‐stranded β6.3 helices with 6.3 residues per turn, differing from Urry's structure by handedness of the helices.

Bibliography

Arseniev, A. S., Barsukov, I. L., Bystrov, V. F., Lomize, A. L., & Ovchinnikov, Yu. A. (1985). 1HâNMR study of gramicidin A transmembrane ion channel. FEBS Letters, 186(2), 168â174. Portico.

Authors 5

A.S. Arseniev (first)
I.L. Barsukov (additional)
V.F. Bystrov (additional)
A.L. Lomize (additional)
Yu.A. Ovchinnikov (additional)

References 26 Referenced 246

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10.1002/bip.360210508

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:58 a.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 3:31 a.m.)
Indexed	2 months ago (July 2, 2025, 1:24 a.m.)
Issued	40 years, 1 month ago (July 8, 1985)
Published	40 years, 1 month ago (July 8, 1985)
Published Online	23 years, 9 months ago (Dec. 3, 2001)
Published Print	40 years, 1 month ago (July 8, 1985)

Funders 0

None

BibTeX

@article{Arseniev_1985, title={1H‐NMR study of gramicidin A transmembrane ion channel: Head‐to‐head right‐handed, single‐stranded helices}, volume={186}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(85)80702-x}, DOI={10.1016/0014-5793(85)80702-x}, number={2}, journal={FEBS Letters}, publisher={Wiley}, author={Arseniev, A.S. and Barsukov, I.L. and Bystrov, V.F. and Lomize, A.L. and Ovchinnikov, Yu.A.}, year={1985}, month=jul, pages={168–174} }

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