DOI: 10.1016/0014-5793(85)80241-6. Thrombin induces the rapid formation of inositol bisphosphate and inositol trisphosphate in human platelets

Thrombin induces the rapid formation of inositol bisphosphate and inositol trisphosphate in human platelets

10.1016/0014-5793(85)80241-6

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

Human platelets prelabeled with [3H]inositol were exposed to thrombin. The aqueous soluble inositol phosphates were separated by anion exchange column chromatography, paper chromatography or high‐performance liquid chromatography, and identified by cochromatography with authentic standard substances. Thrombin immediately induces the rapid formation of inositol 1,4‐bisphosphate and inositol 1,4,5‐trisphosphate. Accumulation of inositol‐1‐monophosphate and inositol‐2‐monophosphate occurs later after a time lag of 10 sec. The results indicate that the phospholipase C induced polyphosphoinositide hydrolysis rather than the phosphatidylinositol hydrolysis is the triggering event for platelet activation, and support the concept of inositol 1,4,5‐trisphosphate as putative second messenger.

Bibliography

Siess, W., & Binder, H. (1985). Thrombin induces the rapid formation of inositol bisphosphate and inositol trisphosphate in human platelets. FEBS Letters, 180(1), 107â112. Portico.

Authors 2

Wolfgang Siess (first)
Helge Binder (additional)

References 35 Referenced 12

10.1016/0005-2760(79)90072-9
10.1172/JCI109339
10.1172/JCI109854
10.1111/j.1365-2141.1973.tb01718.x
10.1016/S0021-9258(17)44408-5
{'key': 'e_1_2_1_7_1', 'author': 'Siess W.', 'year': '1984', 'journal-title': 'Blood'} / Blood by Siess W. (1984)
10.1042/bj2200345
10.1038/306067a0
10.1016/0968-0004(83)90061-0
10.1016/S0021-9258(18)32882-5
10.1016/S0021-9258(18)32273-7
10.1016/S0021-9258(18)32473-6
10.1016/S0021-9258(17)39725-9
{'key': 'e_1_2_1_15_1', 'author': 'Siess W.', 'year': '1984', 'journal-title': 'Biochim. Biophys. Acta'} / Biochim. Biophys. Acta by Siess W. (1984)
10.1016/0024-3205(83)90654-9
10.1016/0304-4157(75)90017-9
10.1042/bj1620061
10.1098/rstb.1981.0177
10.1016/S0021-9258(18)33568-3
10.1016/S0021-9258(18)64427-8
{'key': 'e_1_2_1_22_1', 'first-page': '871', 'volume': '38', 'author': 'Desjobert A.', 'year': '1956', 'journal-title': 'Bull. Soc. Chim. Biol.'} / Bull. Soc. Chim. Biol. by Desjobert A. (1956)
10.1016/S0021-9258(18)64103-1
10.1042/bj2220269
10.1016/S0021-9258(18)34655-6
10.1016/0005-2760(83)90131-5
10.1016/0014-5793(75)80041-X
{'key': 'e_1_2_1_28_1', 'first-page': '915', 'volume': '85', 'author': 'Pizer F.L.', 'year': '1958', 'journal-title': 'J. Am. Chetn. Soc.'} / J. Am. Chetn. Soc. by Pizer F.L. (1958)
10.1139/y59-099
10.1042/bj2120473
10.1016/S0021-9258(18)70226-3
10.1016/0005-2760(81)90094-1
10.1042/bj2230237
10.1042/bj2120849
10.1016/S0021-9258(18)91052-5
10.1042/bj2030169

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:58 a.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 2:09 a.m.)
Indexed	1 year, 10 months ago (Oct. 20, 2023, 6:42 p.m.)
Issued	40 years, 7 months ago (Jan. 21, 1985)
Published	40 years, 7 months ago (Jan. 21, 1985)
Published Online	23 years, 9 months ago (Nov. 2, 2001)
Published Print	40 years, 7 months ago (Jan. 21, 1985)

Funders 0

None

BibTeX

@article{Siess_1985, title={Thrombin induces the rapid formation of inositol bisphosphate and inositol trisphosphate in human platelets}, volume={180}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(85)80241-6}, DOI={10.1016/0014-5793(85)80241-6}, number={1}, journal={FEBS Letters}, publisher={Wiley}, author={Siess, Wolfgang and Binder, Helge}, year={1985}, month=jan, pages={107–112} }

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