Abstract
Thermal denaturation of cytochrome P450 is shown to be a complex process which occurs in two steps. The first (about 50°C) takes place in several stages which can be attributed to denaturation of different regions in the cytochrome P450 with different stability. The second transition (about 90°C) is fully reversible and similar to those described for other hemoproteins.
References
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Dates
Type | When |
---|---|
Created | 23 years, 1 month ago (July 25, 2002, 1:12 a.m.) |
Deposited | 1 year, 11 months ago (Sept. 16, 2023, 11:01 a.m.) |
Indexed | 11 months, 2 weeks ago (Sept. 15, 2024, 8:58 p.m.) |
Issued | 42 years, 9 months ago (Nov. 29, 1982) |
Published | 42 years, 9 months ago (Nov. 29, 1982) |
Published Online | 23 years, 10 months ago (Nov. 1, 2001) |
Published Print | 42 years, 9 months ago (Nov. 29, 1982) |
@article{Anzenbacher_1982, title={Study of thermal stability of cytochrome P450 by differential scanning calorimetry}, volume={149}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/0014-5793(82)81102-2}, DOI={10.1016/0014-5793(82)81102-2}, number={2}, journal={FEBS Letters}, publisher={Wiley}, author={Anzenbacher, Pavel and Hudeček, Jiří and Stružinský, Rudolf}, year={1982}, month=nov, pages={208–210} }