DOI: 10.1016/0006-8993(87)91323-0. Effects of ethanol on CA1 and CA3 pyramidal cells in the hippocampal slice preparation: an intracellular study

Effects of ethanol on CA1 and CA3 pyramidal cells in the hippocampal slice preparation: an intracellular study

10.1016/0006-8993(87)91323-0

Crossref journal-article

Elsevier BV

Brain Research (78)

Bibliography

Siggins, G. R., Pittman, Q. J., & French, E. D. (1987). Effects of ethanol on CA1 and CA3 pyramidal cells in the hippocampal slice preparation: an intracellular study. Brain Research, 414(1), 22â34.

Authors 3

G.R. Siggins (first)
Q.J. Pittman (additional)
E.D. French (additional)

References 51 Referenced 121

10.1111/j.1600-0773.1984.tb01998.x / Acta Pharmacol. Toxicol. / Binding of β-carbolines and tetrahydroisoquinolines by opiate receptors of the γ-type by Airaksinen (1984)
10.1126/science.7444438 / Science / Epileptiform burst afterhyperpolarization: calcium-dependent potassium potential in hippocampal CA1 cells by Alger (1980)
10.1038/281315a0 / Nature (London) / GABA-mediated biphasic inhibitory responses in hippocampus by Alger (1979)
10.1016/S0091-6773(72)80196-2 / Behav. Biol. / Effects of ethanol on evoked potentials in the rat by Begleiter (1972)
10.1016/0091-3057(82)90365-3 / Pharmacol. Biochem. Behav. / Ethanol and some tetrahydroisoquinolines alter the discharge of rat hippocampal neurons in vivo when applied by microelectroosmosis or pressure: relationship to opiate action by Berger (1982)
{'key': '10.1016/0006-8993(87)91323-0_bib6', 'series-title': 'Psychopharmacology of Alcohol', 'first-page': '43', 'article-title': 'The neurophysiology of alcohol', 'author': 'Berry', 'year': '1980'} / Psychopharmacology of Alcohol / The neurophysiology of alcohol by Berry (1980)
10.1126/science.7053581 / Science / Ethanol in low doses augments calcium-mediated mechanisms measured intracellularly in hippocampal neurons by Carlen (1982)
{'key': '10.1016/0006-8993(87)91323-0_bib8', 'first-page': '824', 'article-title': 'Effects of ethanol on neurotransmitter release by rat brain cortical slices', 'volume': '193', 'author': 'Carmichael', 'year': '1975', 'journal-title': 'J. Pharmacol. Exp. Ther.'} / J. Pharmacol. Exp. Ther. / Effects of ethanol on neurotransmitter release by rat brain cortical slices by Carmichael (1975)
10.1126/science.167.3926.1749 / Science / Alkaloids from catecholamines in adrenal tissue: possible role in alcoholism by Cohen (1970)
10.1001/archneur.1973.00490190078011 / Arch. Neurol. / Alcohol and presynaptic inhibition in an isolated spinal cord preparation by Davidofff (1973)
10.1126/science.167.3920.1005 / Science / Alcohol, amines and alkaloids: a possible biochemical basis for alcohol addiction by Davis (1970)
10.1139/y81-149 / Can. J. Physiol. Pharmacol. / Effects of low concentrations of ethanol on CA1 hippocampal neurons in vitro by Durand (1981)
{'key': '10.1016/0006-8993(87)91323-0_bib13', 'series-title': 'Alcohol and Opiates: Neurochemical and Behavioral Mechanisms', 'first-page': '41', 'article-title': 'Actions of ethanol on neuronal membrane properties and synaptic transmission', 'author': 'Faber', 'year': '1977'} / Alcohol and Opiates: Neurochemical and Behavioral Mechanisms / Actions of ethanol on neuronal membrane properties and synaptic transmission by Faber (1977)
10.1113/jphysiol.1975.sp010806 / J. Physiol. (London) / Effects of some aliphatic alcohols on the conductance change caused by a quantum of acetylcholine at the toad end-plate by Gage (1975)
{'key': '10.1016/0006-8993(87)91323-0_bib15', 'first-page': '1', 'article-title': 'Effects of alcohol on the neuron', 'volume': 'Vol. 1', 'author': 'Grenell', 'year': '1972'} / Effects of alcohol on the neuron by Grenell (1972)
10.1016/0006-8993(82)91117-9 / Brain Research / Ethanol alters synaptic activity in cultured spinal cord neurons by Gruol (1982)
{'key': '10.1016/0006-8993(87)91323-0_bib17', 'series-title': 'Catecholamines: Neuropharmacology and Central Nervous System — Theoretical Aspects', 'first-page': '131', 'article-title': 'Adrenergic agonists alter the intracellularly recorded spontaneous activity and postdischarge after-hyperpolarization of pyramidal neurons of the rat hippocampus in vitro', 'author': 'Gruol', 'year': '1984'} / Catecholamines: Neuropharmacology and Central Nervous System — Theoretical Aspects / Adrenergic agonists alter the intracellularly recorded spontaneous activity and postdischarge after-hyperpolarization of pyramidal neurons of the rat hippocampus in vitro by Gruol (1984)
10.1007/BF00432377 / Psychopharmacology / Biphasic action of ethanol on single units of the dorsal hippocampus and the relationship to the cortical EEG by Grupp (1980)
10.1038/302432a0 / Nature (London) / Histamine and noradrenaline decrease calcium-activated potassium conductance in hippocampal pyramidal cells by Haas (1983)
10.1126/science.6270788 / Science / Multiple opiate receptors: alcohol selectively inhibits binding to delta receptors by Hiller (1981)
10.15288/qjsa.1953.14.363 / Q. J. Stud. Alcohol. / The influence of ethyl alcohol on the spontaneous electrical activity of the cerebral cortex and subcortical structures of the cat by Horsey (1953)
10.1152/jn.1980.43.2.409 / J. Neurophysiol. / A calcium-activated hyperpolarization follows repetitive firing in hippocampal neurons by Hotson (1980)
10.1016/0741-8329(84)90024-7 / Alcohol / Ethanol-induced inhibition of GABA release from LS and SS mouse brain slices by Howerton (1984)
10.1126/science.138.3545.1104 / Science / Hippocampal ablation and passive avoidance by Isaacson (1962)
{'key': '10.1016/0006-8993(87)91323-0_bib25', 'first-page': '111', 'article-title': 'Ethanol and the nervous system. Experimental neurophysiological aspects', 'volume': '9', 'author': 'Kalant', 'year': '1974', 'journal-title': 'Int. J. Neurol.'} / Int. J. Neurol. / Ethanol and the nervous system. Experimental neurophysiological aspects by Kalant (1974)
10.1007/BF00426822 / Pscyhopharmacology / Ethanol-induced regional and dose-response differences in multiple unit activity in rabbits by Klemm (1976)
10.1146/annurev.ne.03.030180.000245 / Annu. Rev. Neurosci. / The use of in vitro brain slices for multidisciplinary studies of synaptic function by Lynch (1980)
10.1038/303175a0 / Nature (London) / Possible association of alcohol tolerance with increased synaptic Ca2+ sensitivity by Lynch (1983)
10.1038/299636a0 / Nature (London) / Noradrenaline blocks accommodation of pyramidal cell discharge in the hippocampus by Madison (1982)
10.1126/science.2867600 / Science / Systemic ethanol: selective enhancement of responses to acetylcholine and somatostatin in the rat hippocampus by Mancillas (1986)
10.1016/0006-8993(77)90138-X / Brain Research / A pressure system for intracellular and extracellular ejections of picoliter volumes by McCaman (1977)
10.1146/annurev.pa.18.040178.001013 / Rev. Pharmacol. Toxicol. / Psychopharmacology of alcohol by Myers (1978)
10.1038/260538a0 / Nature (London) / Aspartate and glutamate as possible transmitter of excitatory hippocampal afferents by Nadler (1976)
10.1126/science.7394531 / Science / Ethanol specifically potentiates GABA-mediated neurotransmission in feline cerebral cortex by Nesteros (1980)
10.1016/0006-8993(81)91175-6 / Brain Research / Ethanol causes increases in excitation and inhibition in area CA3 of the dorsal hippocampus by Newlin (1981)
{'key': '10.1016/0006-8993(87)91323-0_bib36', 'first-page': '2584', 'article-title': 'Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study', 'volume': '74', 'author': 'Nicoll', 'year': '1977'} / Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study by Nicoll (1977)
10.2170/jjphysiol.17.245 / Jap. J. Physiol. / Effects of alcohols and acetone on the neuromuscular junction of frog by Okada (1967)
{'year': '1978', 'series-title': 'The Hippocampus as a Cognitive map', 'author': "O'Keefe", 'key': '10.1016/0006-8993(87)91323-0_bib38'} / The Hippocampus as a Cognitive map by O'Keefe (1978)
10.1016/0013-4694(74)90133-3 / Electroenceph. Clin. Neurophysiol. / Acute effects of ethanol on spontaneous and auditory evoked electrical activity in cat brain by Perrin (1974)
{'key': '10.1016/0006-8993(87)91323-0_bib40', 'first-page': '771', 'article-title': 'Ethanol has multiple actions on electrophysiological properties of hippocampal (HPC) pyramidal neurons in vitro', 'volume': '6', 'author': 'Pittman', 'year': '1980', 'journal-title': 'Soc. Neurosci. Abstr.'} / Soc. Neurosci. Abstr. / Ethanol has multiple actions on electrophysiological properties of hippocampal (HPC) pyramidal neurons in vitro by Pittman (1980)
10.1016/0006-8993(80)90725-8 / Brain Research / Physiological correlates of ethanol intoxication, tolerance, and dependence in rat cerebellar Purkinje cells by Rogers (1979)
10.1126/science.6777871 / Science / Effects of EGTA on the calcium-activated afterhyperpolarization in hippocampal CA3 pyramidal cells by Schwartzkroin (1980)
10.1016/0741-8329(85)90052-7 / Alcohol / Basal firing rate of rat locus coeruleus neurons affects sensitivity to ethanol by Shefner (1985)
{'key': '10.1016/0006-8993(87)91323-0_bib44', 'series-title': 'Beta-Carbolines and Tetrahydroisoquinolines', 'first-page': '275', 'article-title': 'Ethanol, salsolinol and tetrahydropapaveroline alter the discharge of neurons in several brain regions: comparisons to opioid effects', 'author': 'Siggins', 'year': '1982'} / Beta-Carbolines and Tetrahydroisoquinolines / Ethanol, salsolinol and tetrahydropapaveroline alter the discharge of neurons in several brain regions: comparisons to opioid effects by Siggins (1982)
10.1016/S0091-3057(80)80032-3 / Pharmacol. Biochem. Behav. / Alcohol-related electrophysiology by Siggins (1981)
Siggins, G.R., Bloom, F.E., French, E.D., Madamba, S.G., Mancillas, J., Pittman, Q.J. and Rogers, J., Electrophysiology of ethanol on central neurons,Ann. N.Y. Acad. Sci., in press. (10.1111/j.1749-6632.1987.tb48692.x)
{'key': '10.1016/0006-8993(87)91323-0_bib47', 'first-page': '5235', 'article-title': 'Morphine and opioid peptides reduce inhibitory synaptic potentials in hippocampal pyramidal cells in vitro without alteration of membrane potential', 'volume': '78', 'author': 'Siggins', 'year': '1981'} / Morphine and opioid peptides reduce inhibitory synaptic potentials in hippocampal pyramidal cells in vitro without alteration of membrane potential by Siggins (1981)
10.1016/0091-3057(81)90248-3 / Pharmacol. Biochem. Behav. / Ethanol-induced depressions in cerebellar and hippocampal neurons of mice selectively bred for differences in ethanol sensitivity: an electrophysiological study by Sorensen (1981)
10.1001/archneur.1961.00450170103013 / Arch. Neurol. / Electrographic changes induced in cats by ethanol intoxication by Story (1961)
{'key': '10.1016/0006-8993(87)91323-0_bib50', 'first-page': '726', 'article-title': 'Membrane properties and aging: in vivo and in vitro effects of ethanol on synaptosomal gamma-aminobutyric acid (GABA) release', 'volume': '229', 'author': 'Strong', 'year': '1984', 'journal-title': 'J. Pharmacol. Exp. Ther.'} / J. Pharmacol. Exp. Ther. / Membrane properties and aging: in vivo and in vitro effects of ethanol on synaptosomal gamma-aminobutyric acid (GABA) release by Strong (1984)
10.1126/science.451610 / Science / Opioid peptides may excite hippocampal pyramidal neurons by inhibiting adjacent inhibitory interneurons by Zieglga¨nsberger (1979)

Dates

Type	When
Created	22 years, 4 months ago (April 24, 2003, 3:52 p.m.)
Deposited	4 years, 3 months ago (June 6, 2021, 4:56 a.m.)
Indexed	2 days, 11 hours ago (Sept. 4, 2025, 9:26 a.m.)
Issued	38 years, 3 months ago (June 1, 1987)
Published	38 years, 3 months ago (June 1, 1987)
Published Print	38 years, 3 months ago (June 1, 1987)

Funders 0

None

BibTeX

@article{Siggins_1987, title={Effects of ethanol on CA1 and CA3 pyramidal cells in the hippocampal slice preparation: an intracellular study}, volume={414}, ISSN={0006-8993}, url={http://dx.doi.org/10.1016/0006-8993(87)91323-0}, DOI={10.1016/0006-8993(87)91323-0}, number={1}, journal={Brain Research}, publisher={Elsevier BV}, author={Siggins, G.R. and Pittman, Q.J. and French, E.D.}, year={1987}, month=jun, pages={22–34} }

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      "author": "Berger",
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      "author": "Carlen",
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      "author": "Carmichael",
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      "article-title": "Alkaloids from catecholamines in adrenal tissue: possible role in alcoholism",
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      "author": "Cohen",
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      "volume": "244",
      "author": "Gage",
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      "DOI": "10.1146/annurev.ne.03.030180.000245",
      "article-title": "The use of in vitro brain slices for multidisciplinary studies of synaptic function",
      "volume": "3",
      "author": "Lynch",
      "year": "1980",
      "journal-title": "Annu. Rev. Neurosci."
    },
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      "first-page": "175",
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      "article-title": "Possible association of alcohol tolerance with increased synaptic Ca2+ sensitivity",
      "volume": "303",
      "author": "Lynch",
      "year": "1983",
      "journal-title": "Nature (London)"
    },
    {
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      "first-page": "636",
      "DOI": "10.1038/299636a0",
      "article-title": "Noradrenaline blocks accommodation of pyramidal cell discharge in the hippocampus",
      "volume": "299",
      "author": "Madison",
      "year": "1982",
      "journal-title": "Nature (London)"
    },
    {
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      "first-page": "161",
      "DOI": "10.1126/science.2867600",
      "article-title": "Systemic ethanol: selective enhancement of responses to acetylcholine and somatostatin in the rat hippocampus",
      "volume": "231",
      "author": "Mancillas",
      "year": "1986",
      "journal-title": "Science"
    },
    {
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      "DOI": "10.1016/0006-8993(77)90138-X",
      "article-title": "A pressure system for intracellular and extracellular ejections of picoliter volumes",
      "volume": "136",
      "author": "McCaman",
      "year": "1977",
      "journal-title": "Brain Research"
    },
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      "DOI": "10.1146/annurev.pa.18.040178.001013",
      "article-title": "Psychopharmacology of alcohol",
      "volume": "18",
      "author": "Myers",
      "year": "1978",
      "journal-title": "Rev. Pharmacol. Toxicol."
    },
    {
      "key": "10.1016/0006-8993(87)91323-0_bib33",
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      "first-page": "538",
      "DOI": "10.1038/260538a0",
      "article-title": "Aspartate and glutamate as possible transmitter of excitatory hippocampal afferents",
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      "author": "Nadler",
      "year": "1976",
      "journal-title": "Nature (London)"
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    {
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      "DOI": "10.1126/science.7394531",
      "article-title": "Ethanol specifically potentiates GABA-mediated neurotransmission in feline cerebral cortex",
      "volume": "209",
      "author": "Nesteros",
      "year": "1980",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0006-8993(87)91323-0_bib35",
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      "first-page": "113",
      "DOI": "10.1016/0006-8993(81)91175-6",
      "article-title": "Ethanol causes increases in excitation and inhibition in area CA3 of the dorsal hippocampus",
      "volume": "209",
      "author": "Newlin",
      "year": "1981",
      "journal-title": "Brain Research"
    },
    {
      "key": "10.1016/0006-8993(87)91323-0_bib36",
      "first-page": "2584",
      "article-title": "Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study",
      "volume": "74",
      "author": "Nicoll",
      "year": "1977"
    },
    {
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      "first-page": "245",
      "DOI": "10.2170/jjphysiol.17.245",
      "article-title": "Effects of alcohols and acetone on the neuromuscular junction of frog",
      "volume": "17",
      "author": "Okada",
      "year": "1967",
      "journal-title": "Jap. J. Physiol."
    },
    {
      "year": "1978",
      "series-title": "The Hippocampus as a Cognitive map",
      "author": "O'Keefe",
      "key": "10.1016/0006-8993(87)91323-0_bib38"
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      "first-page": "19",
      "DOI": "10.1016/0013-4694(74)90133-3",
      "article-title": "Acute effects of ethanol on spontaneous and auditory evoked electrical activity in cat brain",
      "volume": "36",
      "author": "Perrin",
      "year": "1974",
      "journal-title": "Electroenceph. Clin. Neurophysiol."
    },
    {
      "key": "10.1016/0006-8993(87)91323-0_bib40",
      "first-page": "771",
      "article-title": "Ethanol has multiple actions on electrophysiological properties of hippocampal (HPC) pyramidal neurons in vitro",
      "volume": "6",
      "author": "Pittman",
      "year": "1980",
      "journal-title": "Soc. Neurosci. Abstr."
    },
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      "first-page": "183",
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      "article-title": "Physiological correlates of ethanol intoxication, tolerance, and dependence in rat cerebellar Purkinje cells",
      "volume": "196",
      "author": "Rogers",
      "year": "1979",
      "journal-title": "Brain Research"
    },
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      "DOI": "10.1126/science.6777871",
      "article-title": "Effects of EGTA on the calcium-activated afterhyperpolarization in hippocampal CA3 pyramidal cells",
      "volume": "210",
      "author": "Schwartzkroin",
      "year": "1980",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/0006-8993(87)91323-0_bib43",
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      "first-page": "239",
      "DOI": "10.1016/0741-8329(85)90052-7",
      "article-title": "Basal firing rate of rat locus coeruleus neurons affects sensitivity to ethanol",
      "volume": "2",
      "author": "Shefner",
      "year": "1985",
      "journal-title": "Alcohol"
    },
    {
      "key": "10.1016/0006-8993(87)91323-0_bib44",
      "series-title": "Beta-Carbolines and Tetrahydroisoquinolines",
      "first-page": "275",
      "article-title": "Ethanol, salsolinol and tetrahydropapaveroline alter the discharge of neurons in several brain regions: comparisons to opioid effects",
      "author": "Siggins",
      "year": "1982"
    },
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      "first-page": "203",
      "DOI": "10.1016/S0091-3057(80)80032-3",
      "article-title": "Alcohol-related electrophysiology",
      "volume": "13",
      "author": "Siggins",
      "year": "1981",
      "journal-title": "Pharmacol. Biochem. Behav."
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      "DOI": "10.1111/j.1749-6632.1987.tb48692.x"
    },
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      "key": "10.1016/0006-8993(87)91323-0_bib47",
      "first-page": "5235",
      "article-title": "Morphine and opioid peptides reduce inhibitory synaptic potentials in hippocampal pyramidal cells in vitro without alteration of membrane potential",
      "volume": "78",
      "author": "Siggins",
      "year": "1981"
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      "DOI": "10.1016/0091-3057(81)90248-3",
      "article-title": "Ethanol-induced depressions in cerebellar and hippocampal neurons of mice selectively bred for differences in ethanol sensitivity: an electrophysiological study",
      "volume": "14",
      "author": "Sorensen",
      "year": "1981",
      "journal-title": "Pharmacol. Biochem. Behav."
    },
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      "first-page": "565",
      "DOI": "10.1001/archneur.1961.00450170103013",
      "article-title": "Electrographic changes induced in cats by ethanol intoxication",
      "volume": "5",
      "author": "Story",
      "year": "1961",
      "journal-title": "Arch. Neurol."
    },
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      "first-page": "726",
      "article-title": "Membrane properties and aging: in vivo and in vitro effects of ethanol on synaptosomal gamma-aminobutyric acid (GABA) release",
      "volume": "229",
      "author": "Strong",
      "year": "1984",
      "journal-title": "J. Pharmacol. Exp. Ther."
    },
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      "article-title": "Opioid peptides may excite hippocampal pyramidal neurons by inhibiting adjacent inhibitory interneurons",
      "volume": "205",
      "author": "Zieglga\u00a8nsberger",
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