Discovery of the molecular machinery CERT for endoplasmic reticulum-to-Golgi trafficking of ceramide
10.1007/s11010-005-9044-z
Crossref journal-article
Springer Science and Business Media LLC
Molecular and Cellular Biochemistry (297)
Bibliography

Hanada, K. (2006). Discovery of the molecular machinery CERT for endoplasmic reticulum-to-Golgi trafficking of ceramide. Molecular and Cellular Biochemistry, 286(1–2), 23–31.

Authors 1
  1. Kentaro Hanada (first)
References 46 Referenced 70
  1. Lee MC, Miller EA, Goldberg J, Orci L, Schekman R: Bi-Directional Protein Transport between the ER and Golgi. Annu Rev Cell Dev Biol 20: 87–123, 2004 (10.1146/annurev.cellbio.20.010403.105307) / Annu Rev Cell Dev Biol by Lee MC (2004)
  2. Palmer KJ, Stephens DJ: Biogenesis of ER-to-Golgi transport carriers: complex roles of COPII in ER export. Trends Cell Biol 14: 57–61, 2004 (10.1016/j.tcb.2003.12.001) / Trends Cell Biol by KJ Palmer (2004)
  3. Voelker DR: Lipid assembly into cell membranes. In: D. E. Vance, J. Vance, J. (eds). Biochemistry of Lipids, Lipoproteins and Membranes (4th edition). Elsevier Science B. V., Amsterdam 2002, pp. 449–482 / Biochemistry of Lipids, Lipoproteins and Membranes by DR Voelker (2002)
  4. van Meer G, Holthuis JCM: Sphingolipid transport in eukaryotic cells. Biochim Biophys Acta 1486: 145–170, 2000 (10.1016/S1388-1981(00)00054-8) / Biochim Biophys Acta by G van Meer (2000)
  5. Soccio RE, Breslow JL: Intracellular cholesterol transport. Arterioscler Thromb Vasc Biol 24: 1150–1160, 2004 (10.1161/01.ATV.0000131264.66417.d5) / Arterioscler Thromb Vasc Biol by RE Soccio (2004)
  6. Hanada K: Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism. Biochim Biophys Acta 1632: 16–30, 2003 (10.1016/S1388-1981(03)00059-3) / Biochim Biophys Acta by K Hanada (2003)
  7. Wang E, Norred WP, Bacon CW, Riley RT, Merrill AHJ: Inhibition of sphingolipid biosynthesis by fumonisins: Implications for diseases associated with Fusarium moniliforme. J Biol Chem 266: 14486–14490, 1991 (10.1016/S0021-9258(18)98712-0) / J Biol Chem by E Wang (1991)
  8. Mandon EC, Ehses I, Rother J, van Echten G, Sandhoff K: Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver. J Biol Chem 267: 11144–11148, 1992 (10.1016/S0021-9258(19)49887-6) / J Biol Chem by EC Mandon (1992)
  9. Futerman AH, Stieger B, Hubbard AL, Pagano RE: Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus. J Biol Chem 265: 8650–8657, 1990 (10.1016/S0021-9258(19)38937-9) / J Biol Chem by AH Futerman (1990)
  10. Huitema K, van den Dikkenberg J, Brouwers JF, Holthuis JC: Identification of a family of animal sphingomyelin synthases. EMBO J. 23: 33–44, 2004 (10.1038/sj.emboj.7600034) / EMBO J. by K Huitema (2004)
  11. Yamaoka S, Miyaji M, Kitano T, Umehara H, Okazaki T: Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells. J Biol Chem 279: 18688–18693, 2004 (10.1074/jbc.M401205200) / J Biol Chem by S Yamaoka (2004)
  12. Futerman AH, Pagano RE: Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver. Biochem J 280: 295–302, 1991 (10.1042/bj2800295) / Biochem J by AH Futerman (1991)
  13. Jeckel D, Karrenbauer A, Burger KNJ, van Meer G, Wieland F: Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions. J Cell Biol 117: 259–267, 1992 (10.1083/jcb.117.2.259) / J Cell Biol by D Jeckel (1992)
  14. Ardail D, Popa I, Bodennec J, Louisot P, Schmitt D, Portoukalian J: The mitochondria-associated endoplasmic-reticulum subcompartment (MAM fraction) of rat liver contains highly active sphingolipid-specific glycosyltransferases. Biochem J 371: 1013–1019, 2003 (10.1042/bj20021834) / Biochem J by D Ardail (2003)
  15. Kohyama-Koganeya A, Sasamura T, Oshima E, Suzuki E, Nishihara S, Ueda R, Hirabayashi Y: Drosophila glucosylceramide synthase: a negative regulator of cell death mediated by proapoptotic factors. J Biol Chem 279: 35995–36002, 2004 (10.1074/jbc.M400444200) / J Biol Chem by A Kohyama-Koganeya (2004)
  16. Ichikawa S, Sakiyama H, Suzuki G, Hidari KI-PJ, Hirabayashi Y: Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis. Proc Natl Acad Sci USA 93: 4638–4663, 1996 (10.1073/pnas.93.10.4638) / Proc Natl Acad Sci USA by S Ichikawa (1996)
  17. Yamashita T, Wada R, Sasaki T, Deng C, Bierfreund U, Sandhoff K, Proia RL: A vital role for glycosphingolipid synthesis during development and differentiation. Proc Natl Acad Sci USA 96: 9142–9147, 1999 (10.1073/pnas.96.16.9142) / Proc Natl Acad Sci USA by T Yamashita (1999)
  18. Sandhoff K, Kolter T: Biosynthesis and degradation of mammalian glycosphingolipids. Philos Trans R Soc Lond B Biol Sci 358: 847–861, 2003 (10.1098/rstb.2003.1265) / Philos Trans R Soc Lond B Biol Sci by K Sandhoff (2003)
  19. Yamaji A, Sekizawa Y, Emoto K, Sakuraba H, Inoue K, Kobayashi H, Umeda M: Lysenin, a novel sphingomyelin-specific binding protein. J Biol Chem 273: 5300–5306, 1998 (10.1074/jbc.273.9.5300) / J Biol Chem by A Yamaji (1998)
  20. Hanada K, Hara T, Fukasawa M, Yamaji A, Umeda M, Nishijima M: Mammalian cell mutants resistant to a sphingomyelin-directed cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase. J Biol Chem 273: 33787–33794, 1998 / Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase. J Biol Chem by K Hanada (1998)
  21. Fukasawa M, Nishijima M, Hanada K: Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells. J Cell Biol 144: 673–685, 1999 (10.1083/jcb.144.4.673) / J Cell Biol by M Fukasawa (1999)
  22. Funakoshi T, Yasuda S, Fukasawa M, Nishijima M, Hanada K: Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells. J Biol Chem 275: 29938–29945, 2000 (10.1074/jbc.M004470200) / J Biol Chem by T Funakoshi (2000)
  23. Beckers CJM, Keller DS, Balch WE: Semi-intact cells permeable to macromolecules: use in reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex. Cell 50: 523–534, 1987 (10.1016/0092-8674(87)90025-0) / Cell by CJM Beckers (1987)
  24. Fukasawa M, Nishijima M, Itabe H, Takano T, Hanada K: Reduction of sphingomyelin level without accumulation of ceramide in Chinese hamster ovary cells affects detergent-resistant membrane domains and enhances cellular cholesterol efflux to methyl-beta -cyclodextrin. J Biol Chem 275: 34028–34034, 2000 (10.1074/jbc.M005151200) / J Biol Chem by M Fukasawa (2000)
  25. Ohvo-Rekila H, Ramstedt B, Leppimaki P, Slotte JP: Cholesterol interactions with phospholipids in membranes. Prog Lipid Res 41: 66–97, 2002 (10.1016/S0163-7827(01)00020-0) / Prog Lipid Res by H Ohvo-Rekila (2002)
  26. Kitamura T, Koshino Y, Shibata F, Oki T, Nakajima H, Nosaka T, Kumagai H: Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. Exp Hematol 31: 1007–1014, 2003 (10.1016/j.exphem.2003.07.005) / Exp Hematol by T Kitamura (2003)
  27. Siess DC, Kozak SL, Kabat D: Exceptional fusogenicity of Chinese hamster ovary cells with murine retroviruses suggests roles for cellular factor(s) and receptor clusters in the membrane fusion process. J Virol 70: 3432–3439, 1996 (10.1128/JVI.70.6.3432-3439.1996) / J Virol by DC Siess (1996)
  28. Hanada K, Kumagai K, Yasuda S, Miura Y, Kawano M, Fukasawa M, Nishijima M: Molecular machinery for non-vesicular trafficking of ceramide. Nature 426: 803–809, 2003 (10.1038/nature02188) / Nature by K Hanada (2003)
  29. Raya A, Revert F, Navarro S, Saus J: Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen. J Biol Chem 274: 12642–12649, 1999 (10.1074/jbc.274.18.12642) / J Biol Chem by A Raya (1999)
  30. Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR: Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem J 351: 19–31, 2000 (10.1042/bj3510019) / Biochem J by S Dowler (2000)
  31. Ponting CP, Aravind L: START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins. Trends Biochem Sci 24: 130–132, 1999 (10.1016/S0968-0004(99)01362-6) / Trends Biochem Sci by CP Ponting (1999)
  32. Simon CG, Jr., Holloway PW, Gear AR: Exchange of C(16)-ceramide between phospholipid vesicles. Biochemistry 38: 14676–14682, 1999 (10.1021/bi991537w) / Biochemistry by CG Simon Jr. (1999)
  33. Soccio RE, Breslow JL: StAR-related lipid transfer (START) proteins: mediators of intracellular lipid metabolism. J Biol Chem 278: 22183–22186, 2003 (10.1074/jbc.R300003200) / J Biol Chem by RE Soccio (2003)
  34. Kumagai K, Yasuda S, Okemoto K, Nishijima M, Kobayashi S, Hanada K: CERT mediates intermembrane transfer of various molecular species of ceramides. J Biol Chem 6488–6495: 2005 (10.1074/jbc.M409290200)
  35. Wang YJ, Wang J, Sun HQ, Martinez M, Sun YX, Macia E, Kirchhausen T, Albanesi JP, Roth MG, Yin HL: Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell 114: 299–310, 2003 (10.1016/S0092-8674(03)00603-2) / Cell by YJ Wang (2003)
  36. Levine TP, Munro S: Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components. Curr Biol 12: 695–704, 2002 (10.1016/S0960-9822(02)00779-0) / Curr Biol by TP Levine (2002)
  37. Loewen CJ, Roy A, Levine TP: A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP. EMBO J 22: 2025–2035, 2003 (10.1093/emboj/cdg201) / EMBO J by CJ Loewen (2003)
  38. Kuge O, Dascher C, Orci L, Rowe T, Amherdt M, Plutner H, Ravazzola M, Tanigawa G, Rothman JE, Balch WE: Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments. J Cell Biol 125: 51–65, 1994 (10.1083/jcb.125.1.51) / J Cell Biol by O Kuge (1994)
  39. Mogelsvang S, Marsh BJ, Ladinsky MS, Howell KE: Predicting function from structure: 3D structure studies of the mammalian Golgi complex. Traffic 5: 338–345, 2004 (10.1111/j.1398-9219.2004.00186.x) / Traffic by S Mogelsvang (2004)
  40. Munro S: Cell biology: earthworms and lipid couriers. Nature 426: 775–776, 2003 (10.1038/426775a) / Nature by S Munro (2003)
  41. Raya A, Revert-Ros F, Martinez-Martinez P, Navarro S, Rosello E, Vieites B, Granero F, Forteza J, Saus J: Goodpasture antigen-binding protein, the kinase that phosphorylates the goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis. J Biol Chem 275: 40392–40399, 2000 (10.1074/jbc.M002769200) / J Biol Chem by A Raya (2000)
  42. Riezman H, van Meer G: Lipid pickup and delivery. Nat Cell Biol 6: 15–16, 2004 (10.1038/ncb0104-15) / Nat Cell Biol by H Riezman (2004)
  43. Hannun YA, Luberto C: Lipid metabolism: ceramide transfer protein adds a new dimension. Curr Biol 14: R163–R165, 2004 (10.1016/j.cub.2004.01.049) / Curr Biol by YA Hannun (2004)
  44. Tannert A, Pohl A, Pomorski T, Herrmann A: Protein-mediated transbilayer movement of lipids in eukaryotes and prokaryotes: the relevance of ABC transporters. Int J Antimicrob Agents 22: 177–187, 2003 (10.1016/S0924-8579(03)00217-6) / Int J Antimicrob Agents by A Tannert (2003)
  45. Locher KP, Borths E: ABC transporter architecture and mechanism: implications from the crystal structures of BtuCD and BtuF. FEBS Lett 564: 264–268, 2004 (10.1016/S0014-5793(04)00289-3) / FEBS Lett by KP Locher (2004)
  46. Merrill AH, Jr.: De novo sphingolipid biosynthesis: A necessary, but dangerous, pathway. J Biol Chem 277: 25843–25846, 2002 (10.1074/jbc.R200009200) / J Biol Chem by AH Merrill Jr. (2002)
Dates
Type When
Created 19 years, 4 months ago (April 6, 2006, 10:36 a.m.)
Deposited 4 years, 1 month ago (July 25, 2021, 7 a.m.)
Indexed 2 months, 3 weeks ago (June 4, 2025, 9:16 p.m.)
Issued 19 years, 4 months ago (April 7, 2006)
Published 19 years, 4 months ago (April 7, 2006)
Published Online 19 years, 4 months ago (April 7, 2006)
Published Print 19 years, 2 months ago (June 1, 2006)
Funders 0

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@article{Hanada_2006, title={Discovery of the molecular machinery CERT for endoplasmic reticulum-to-Golgi trafficking of ceramide}, volume={286}, ISSN={1573-4919}, url={http://dx.doi.org/10.1007/s11010-005-9044-z}, DOI={10.1007/s11010-005-9044-z}, number={1–2}, journal={Molecular and Cellular Biochemistry}, publisher={Springer Science and Business Media LLC}, author={Hanada, Kentaro}, year={2006}, month=apr, pages={23–31} }