DOI: 10.1007/s00438-004-0976-x. Creation of EcR isoform-specific mutations in Drosophila melanogaster via local P element transposition, imprecise P element excision, and male recombination

Creation of EcR isoform-specific mutations in Drosophila melanogaster via local P element transposition, imprecise P element excision, and male recombination

10.1007/s00438-004-0976-x

Crossref journal-article

Springer Science and Business Media LLC

Molecular Genetics and Genomics (297)

Bibliography

Carney, G. E., Robertson, A., Davis, M. B., & Bender, M. (2004). Creation of EcR isoform-specific mutations in Drosophila melanogaster via local P element transposition, imprecise P element excision, and male recombination. Molecular Genetics and Genomics, 271(3), 282â290.

Authors 4

G. E. Carney (first)
A. Robertson (additional)
M. B. Davis (additional)
M. Bender (additional)

References 40 Referenced 11

Addison WR, Brook WJ, Querengesser LD, Tiong SY, Russell MA (1995) Analysis of an enhancer trap expressed in regenerating Drosophila imaginal discs. Genome 38:724–736 (10.1139/g95-091) / Genome by Addison (1995)
Bender M, Imam FB, Talbot WS, Ganetzky B, Hogness DS (1997) Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Cell 91:777–788 (10.1016/S0092-8674(00)80466-3) / Cell by Bender (1997)
Bier E, et al (1989). Searching for pattern and mutation in the Drosophila genome with a P- lacZ vector. Genes Dev 3:1273–1287 (10.1101/gad.3.9.1273) / Genes Dev by Bier (1989)
Carney GE (1998) Ecdysone target gene requirements in Drosophila melanogaster during embryogenesis, metamorphosis, and adult female reproduction. PhD Thesis, University of Georgia, Athens, Ga.
Carney GE, Bender M (2000) The Drosophila ecdysone receptor (EcR) gene is required maternally for normal oogenesis. Genetics 154:1203–1211 (10.1093/genetics/154.3.1203) / Genetics by Carney (2000)
D’Avino PP, Thummel CS (2000) The ecdysone regulatory pathway controls wing morphogenesis and integrin expression during Drosophila metamorphosis. Dev Biol 220:211–224 (10.1006/dbio.2000.9650) / Dev Biol by D’Avino (2000)
Dalby B, Pereira AJ, Goldstein LSB (1995) An inverse PCR screen for the detection of P element insertions in cloned genomic intervals in Drosophila melanogaster. Genetics 139:757–766 (10.1093/genetics/139.2.757) / Genetics by Dalby (1995)
Engels WR (1996) P elements in Drosophila. In: Saedler H, Gierl A (eds) Transposable elements. Springer-Verlag, Berlin, pp 103–123. (10.1007/978-3-642-79795-8_5)
Gloor GB, Lankenau DH (1998) Gene conversion in mitoticallydividing cells: a view from Drosophila. Trends Genet 14:43–46 (10.1016/S0168-9525(97)01365-6) / Trends Genet by Gloor (1998)
Gloor GB, Nassif NA, Johnson-Schlitz DM, Preston CR, Engels WR (1991) Targeted gene replacement in Drosophila via P-element-induced gap repair. Science 253:1110–1117 (10.1126/science.1653452) / Science by Gloor (1991)
Gray YHM, Tanaka MM, Sved JA (1996) P-element-induced recombination in Drosophila melanogaster: hybrid element insertion. Genetics 144:1601–1610 (10.1093/genetics/144.4.1601) / Genetics by Gray (1996)
Hamer L, DeZwaan TM, Montenegro-Chamorro MV, Frank SA, Hamer JE (2001) Recent advances in large-scale transposon mutagenesis. Curr Opin Chem Biol 5:67–73 (10.1016/S1367-5931(00)00162-9) / Curr Opin Chem Biol by Hamer (2001)
Hamilton BA, Zinn K (1994) From clone to mutant gene. In: Goldstein LSB, Fyrberg EA (eds) Drosophila melanogaster: practical uses in cell and molecular biology. Academic Press, New York (10.1016/S0091-679X(08)60907-3)
Kastner P, Mark M, Chambon P (1995) Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell 83:859–869 (10.1016/0092-8674(95)90202-3) / Cell by Kastner (1995)
Keightly MC (1998) Steroid receptor isoforms: exception or rule? Mol Cell Endocrinol 137:1–5 (10.1016/S0303-7207(97)00236-0) / Mol Cell Endocrinol by Keightly (1998)
Koelle MR, Talbot WS, Segraves WA, Bender MT, Cherbas P, Hogness DS (1991) The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily. Cell 67:59–77 (10.1016/0092-8674(91)90572-G) / Cell by Koelle (1991)
Lindsley DL, Zimm GG (1992) The genome of Drosophila melanogaster. Academic Press, San Diego
Matthews BB, Crews ST (1999) Drosophila center divider gene is expressed in CNS midline cells and encodes a developmentally regulated protein kinase orthologous to human TESK1. DNA Cell Biol 18:435–448 (10.1089/104454999315150) / DNA Cell Biol by Matthews (1999)
Preston CR, Engels WR (1996) P-element-induced male recombination and gene conversion in Drosophila. Genetics 144:1611–1622 (10.1093/genetics/144.4.1611) / Genetics by Preston (1996)
Preston CR, Sved JA, Engels WR (1996) Flanking duplications and deletions associated with P-induced male recombination in Drosophila. Genetics 144:1623–1638. (10.1093/genetics/144.4.1623) / Genetics by Preston (1996)
Robertson HM, Preston CR, Phillis RW, Johnson-Schlitz DM, Benz WK, Engels WR (1988) A stable genomic source of P element transposase in Drosophila melanogaster. Genetics 118:461–470 (10.1093/genetics/118.3.461) / Genetics by Robertson (1988)
Robinow S, Talbot WS, Hogness DS, Truman J W (1993) Programmed cell death in the Drosophila CNS is ecdysone-regulated and coupled with a specific ecdysone receptor isoform. Development 199:1251–1259 (10.1242/dev.119.4.1251) / Development by Robinow (1993)
Robinow S, Draizen TA, Truman JW (1997) Genes that induce apoptosis: transcriptional regulation in identified, doomed neurons of the Drosophila CNS. Dev Biol 190:206–213 (10.1006/dbio.1997.8696) / Dev Biol by Robinow (1997)
Roignant J-Y, Carre C, Mugat B, Szymczak D, Lepesant JA, Antoniewski C (2003) Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila. RNA 9:299–308 (10.1261/rna.2154103) / RNA by Roignant (2003)
Salz HK, Cline TW, Schedl P (1987) Functional changes associated with structural alterations induced by mobilization of a P element inserted in the Sex-lethal gene of Drosophila. Genetics 117:221–231 (10.1093/genetics/117.2.221) / Genetics by Salz (1987)
Schubiger M, Wade AA, Carney GE, Truman JW, Bender M (1998) Drosophila EcR-B ecdysone receptor isoforms are required for larval molting and for neuron remodeling during metamorphosis. Development 125:2053–2062 (10.1242/dev.125.11.2053) / Development by Schubiger (1998)
Spradling AC, Stern D, Beaton A, Rhem EJ, Laverty T, Mozden N, Misra S, Rubin GM (1999) The Berkeley Drosophila Genome Project gene disruption project: single P-element insertions mutating 25% of vital Drosophila genes. Genetics 153:135–177 (10.1093/genetics/153.1.135) / Genetics by Spradling (1999)
Sung C, Robinow S (2000) Characterization of the regulatory elements controlling neuronal expression of the A-isoform of the ecdysone receptor gene of Drosophila melanogaster. Mech Dev 91:237–248 (10.1016/S0925-4773(99)00310-X) / Mech Dev by Sung (2000)
Sved JA, Eggleston WB, Engels WR (1990) Germ-line and somatic recombination induced by in vitro modified P elements in Drosophila melanogaster. Genetics 124:331–337 (10.1093/genetics/124.2.331) / Genetics by Sved (1990)
Sved JA, Blackman LM, Svoboda Y, Colless R (1995) Male recombination with single and homologous P elements in Drosophila melanogaster. Mol Gen Genet 246:381–386 (10.1007/BF00288612) / Mol Gen Genet by Sved (1995)
Talbot WS, Swyryd EA, Hogness DS (1993) Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms. Cell 73:1323–1337 (10.1016/0092-8674(93)90359-X) / Cell by Talbot (1993)
Torok T, Tick G, Alvarado M, Kiss I (1993) P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster: isolation of lethals with different overgrowth phenotypes. Genetics 135:71–80 (10.1093/genetics/135.1.71) / Genetics by Torok (1993)
Tower J, Karpen GH, Craig N, Spradling AC (1993) Preferential transposition of Drosophila P elements to nearby chromosomal sites. Genetics 133:347–359 (10.1093/genetics/133.2.347) / Genetics by Tower (1993)
Truman JW, Talbot WS, Fahrbach SE, Hogness DS (1994) Ecdysone receptor expression in the CNS correlates with stage-specific responses to ecdysteroids during Drosophila and Manduca development. Development 120:219–234 (10.1242/dev.120.1.219) / Development by Truman (1994)
Tsai C-C, Kao H-Y, Yao T-P, McKeown M, Evans RM (1999) SMRTER, a Drosophila nuclear receptor co-regulator, reveals that EcR mediated repression is critical for development. Mol Cell 4:175–186 (10.1016/S1097-2765(00)80365-2) / Mol Cell by Tsai (1999)
Tsubota S, Schedl P (1986) Hybrid dysgenesis-induced revertants of insertions at the 5′ end of the rudimentary gene in Drosophila melanogaster: transposon-induced control mutations. Genetics 114:165–182 (10.1093/genetics/114.1.165) / Genetics by Tsubota (1986)
Yao TP, Segraves WA, Oro AE, McKeown M, Evans RM (1992) Drosophila Ultraspiracle modulates ecdysone receptor function via heterodimer formation. Cell 71:63–72 (10.1016/0092-8674(92)90266-F) / Cell by Yao (1992)
Yao T-P, Forman BM, Jlang Z, Cherbas L, Chen J-D, McKeown M, Cherbas P, Evans RM (1993) Functional ecdysone receptor is the product of EcR and ultraspiracle genes. Nature 366:476–479 (10.1038/366476a0) / Nature by Yao (1993)
Yeo SL, Lloyd A, Kozak K, Dinh A, Dick T, Yang X, Sakonju S, Chia W (1995) On the functional overlap between two Drosophila POU homeo domain genes and the cell fate specification of a CNS neural precursor. Genes Dev 9:1223–1236 (10.1101/gad.9.10.1223) / Genes Dev by Yeo (1995)
Zhang P, Spradling AC (1993) Efficient and dispersed local P element transposition from Drosophila females. Genetics 133:361–373 (10.1093/genetics/133.2.361) / Genetics by Zhang (1993)

Dates

Type	When
Created	21 years, 7 months ago (Jan. 28, 2004, 7:57 p.m.)
Deposited	4 years, 2 months ago (June 14, 2021, 12:49 a.m.)
Indexed	1 year, 10 months ago (Oct. 6, 2023, 8:01 a.m.)
Issued	21 years, 7 months ago (Jan. 28, 2004)
Published	21 years, 7 months ago (Jan. 28, 2004)
Published Online	21 years, 7 months ago (Jan. 28, 2004)
Published Print	21 years, 5 months ago (April 1, 2004)

Funders 0

None

BibTeX

@article{Carney_2004, title={Creation of EcR isoform-specific mutations in Drosophila melanogaster via local P element transposition, imprecise P element excision, and male recombination}, volume={271}, ISSN={1617-4623}, url={http://dx.doi.org/10.1007/s00438-004-0976-x}, DOI={10.1007/s00438-004-0976-x}, number={3}, journal={Molecular Genetics and Genomics}, publisher={Springer Science and Business Media LLC}, author={Carney, G. E. and Robertson, A. and Davis, M. B. and Bender, M.}, year={2004}, month=jan, pages={282–290} }

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