DOI: 10.1007/s00418-007-0355-x. Physiological importance of RNA and protein mobility in the cell nucleus

Physiological importance of RNA and protein mobility in the cell nucleus

10.1007/s00418-007-0355-x

Crossref journal-article

Springer Science and Business Media LLC

Histochemistry and Cell Biology (297)

Bibliography

Misteli, T. (2007). Physiological importance of RNA and protein mobility in the cell nucleus. Histochemistry and Cell Biology, 129(1), 5â11.

Authors 1

Tom Misteli (first)

References 41 Referenced 84

Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005) Nucleolar proteome dynamics. Nature 433:77–83 (10.1038/nature03207) / Nature by JS Andersen (2005)
Burke B, Stewart CL (2006) The laminopathies: the functional architecture of the nucleus and its contribution to disease. Annu Rev Genomics Hum Genet 7:369–405 (10.1146/annurev.genom.7.080505.115732) / Annu Rev Genomics Hum Genet by B Burke (2006)
Carrero G, Hendzel MJ, de Vries G (2006) Modelling the compartmentalization of splicing factors. J Theor Biol 239:298–312 (10.1016/j.jtbi.2005.07.019) / J Theor Biol by G Carrero (2006)
Dundr M, Hoffmann-Rohrer U, Hu Q, Grummt I, Rothblum LI, Phair RD, Misteli T (2002) A kinetic framework for a mammalian RNA polymerase in vivo. Science 298:1623–1626 (10.1126/science.1076164) / Science by M Dundr (2002)
Dundr M, Hebert MD, Karpova TS, Stanek D, Xu H, Shpargel KB, Meier UT, Neugebauer KM, Matera AG, Misteli T (2004) In vivo kinetics of Cajal body components. J Cell Biol 164:831–842 (10.1083/jcb.200311121) / J Cell Biol by M Dundr (2004)
Görisch SM, Lichter P, Rippe K (2005) Mobility of multi-subunit complexes in the nucleus: accessibility and dynamics of chromatin subcompartments. Histochem Cell Biol 123:217–228 (10.1007/s00418-005-0752-y) / Histochem Cell Biol by SM Görisch (2005)
Gorski SA, Dundr M, Misteli T (2006) The road much traveled: trafficking in the cell nucleus. Curr Opin Cell Biol 18:284–290 (10.1016/j.ceb.2006.03.002) / Curr Opin Cell Biol by SA Gorski (2006)
Gruenbaum Y, Margalit A, Goldman RD, Shumaker DK, Wilson KL (2005) The nuclear lamina comes of age. Nat Rev Mol Cell Biol 6:21–31 (10.1038/nrm1550) / Nat Rev Mol Cell Biol by Y Gruenbaum (2005)
Handwerger KE, Gall JG (2006) Subnuclear organelles: new insights into form and function. Trends Cell Biol 16:19–26 (10.1016/j.tcb.2005.11.005) / Trends Cell Biol by KE Handwerger (2006)
Heessen S, Fornerod M (2007) The inner nuclear envelope as a transcription factor resting place. EMBO Rep 8:914–919 (10.1038/sj.embor.7401075) / EMBO Rep by S Heessen (2007)
Hernandez-Verdun D (2006) The nucleolus: a model for the organization of nuclear functions. Histochem Cell Biol 126:135–148 (10.1007/s00418-006-0212-3) / Histochem Cell Biol by D Hernandez-Verdun (2006)
Houtsmuller AB, Rademakers S, Nigg AL, Hoogstraten D, Hoeijmakers JH, Vermeulen W (1999) Action of DNA repair endonuclease ERCC1/XPF in living cells. Science 284:958–961 (10.1126/science.284.5416.958) / Science by AB Houtsmuller (1999)
Huang S, Deerinck MH, Ellisman MH, Spector DL (1994) In vivo analysis of the stability and transport of nuclear poly(A)+ RNA. J Cell Biol 126:877–899 (10.1083/jcb.126.4.877) / J Cell Biol by S Huang (1994)
Imai S, Nishibayashi S, Takao K, Tomifuji M, Fujino T, Hasegawa M, Takano T (1997) Dissociation of Oct-1 from the nuclear peripheral structure induces the cellular aging-associated collagenase gene expression. Mol Biol Cell 8:2407–2419 (10.1091/mbc.8.12.2407) / Mol Biol Cell by S Imai (1997)
Ivorra C, Kubicek M, Gonzalez JM, Sanz-Gonzalez SM, Alvarez-Barrientos A, O’Connor JE, Burke B, Andres V (2006) A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C. Genes Dev 20:307–320 (10.1101/gad.349506) / Genes Dev by C Ivorra (2006)
Jiménez-García LF, Spector DL (1993) In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism. Cell 73:47–59 (10.1016/0092-8674(93)90159-N) / Cell by LF Jiménez-García (1993)
Johnson BR, Nitta RT, Frock RL, Mounkes L, Barbie DA, Stewart CL, Harlow E, Kennedy BK (2004) A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation. Proc Natl Acad Sci USA 101:9677–9682 (10.1073/pnas.0403250101) / Proc Natl Acad Sci USA by BR Johnson (2004)
Kay RA, Ellis IR, Jones SJ, Perrier S, Florence MM, Schor AM, Schor SL (2005) The expression of migration stimulating factor, a potent oncofetal cytokine, is uniquely controlled by 3′-untranslated region-dependent nuclear sequestration of its precursor messenger RNA. Cancer Res 65:10742–10749 (10.1158/0008-5472.CAN-05-2038) / Cancer Res by RA Kay (2005)
Kruhlak MJ, Lever MA, Fischle W, Verdin E, Bazett-Jones DP, Hendzel MJ (2000) Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments. J Cell Biol 150:41–51 (10.1083/jcb.150.1.41) / J Cell Biol by MJ Kruhlak (2000)
Lamond AI, Sleeman JE (2003) Nuclear substructure and dynamics. Curr Biol 13:R825–R828 (10.1016/j.cub.2003.10.012) / Curr Biol by AI Lamond (2003)
Lanctot C, Cheutin T, Cremer M, Cavalli G, Cremer T (2007) Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions. Nat Rev Genet 8:104–115 (10.1038/nrg2041) / Nat Rev Genet by C Lanctot (2007)
Martindill DM, Risebro CA, Smart N, Franco-Viseras Mdel M, Rosario CO, Swallow CJ, Dennis JW, Riley PR (2007) Nucleolar release of Hand1 acts as a molecular switch to determine cell fate. Nat Cell Biol 9:1131–1141 (10.1038/ncb1633) / Nat Cell Biol by DM Martindill (2007)
McNally JG, Muller WG, Walker D, Wolford R, Hager GL (2000) The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science 287:1262–1265 (10.1126/science.287.5456.1262) / Science by JG McNally (2000)
Meaburn KJ, Misteli T (2007) Cell biology: chromosome territories. Nature 445:379–781 (10.1038/445379a) / Nature by KJ Meaburn (2007)
Mekhail K, Khacho M, Carrigan A, Hache RR, Gunaratnam L, Lee S (2005) Regulation of ubiquitin ligase dynamics by the nucleolus. J Cell Biol 170:733–744 (10.1083/jcb.200506030) / J Cell Biol by K Mekhail (2005)
Mekhail K, Rivero-Lopez L, Al-Masri A, Brandon C, Khacho M, Lee S (2007) Identification of a common subnuclear localization signal. Mol Biol Cell 18:3966–3977 (10.1091/mbc.E07-03-0295) / Mol Biol Cell by K Mekhail (2007)
Meng L, Zhu Q, Tsai RY (2007) Nucleolar trafficking of nucleostemin family proteins: common versus protein-specific mechanisms. Mol Cell Biol (in press) (10.1128/MCB.00635-07)
Misteli T (2001) Protein dynamics: implications for nuclear architecture and gene expression. Science 291:843–847 (10.1126/science.291.5505.843) / Science by T Misteli (2001)
Misteli T (2007) Beyond the sequence: cellular organization of genome function. Cell 128:787–800 (10.1016/j.cell.2007.01.028) / Cell by T Misteli (2007)
Misteli T, Caceres JF, Spector DL (1997) The dynamics of a pre-mRNA splicing factor in living cells. Nature 387:523–527 (10.1038/387523a0) / Nature by T Misteli (1997)
Phair RD, Misteli T (2000) High mobility of proteins in the mammalian cell nucleus. Nature 404:604–609 (10.1038/35007077) / Nature by RD Phair (2000)
Phair RD, Scaffidi P, Elbi C, Vecerova J, Dey A, Ozato K, Brown DT, Hager G, Bustin M, Misteli T (2004) Global nature of dynamic protein–chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol 24:6393–6402 (10.1128/MCB.24.14.6393-6402.2004) / Mol Cell Biol by RD Phair (2004)
Prasanth KV, Spector DL (2007) Eukaryotic regulatory RNAs: an answer to the ‘genome complexity’ conundrum. Genes Dev 21:11–42 (10.1101/gad.1484207) / Genes Dev by KV Prasanth (2007)
Prasanth KV, Prasanth SG, Xuan Z, Hearn S, Freier SM, Bennett CF, Zhang MQ, Spector DL (2005) Regulating gene expression through RNA nuclear retention. Cell 123:249–263 (10.1016/j.cell.2005.08.033) / Cell by KV Prasanth (2005)
Ritland-Politz JC, Tufft RA, Prasanth KV, Baudendistel N, Fogarty KE, Lifshitz LM, Langowski J, Spector DL, Pederson T (2006) Rapid, diffusional shuttling of poly(A)-RNA between nuclear speckles and the nucleoplasm. Mol Cell Biol 17:1239–1249 (10.1091/mbc.e05-10-0952) / Mol Cell Biol by JC Ritland-Politz (2006)
Seksek O, Biwersi J, Verkman AS (1997) Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus. J Cell Biol 138:131–142 (10.1083/jcb.138.1.131) / J Cell Biol by O Seksek (1997)
Shav-Tal Y, Darzacq X, Shenoy SM, Fusco D, Janicki SM, Spector DL, Singer RH (2004) Dynamics of single mRNPs in nuclei of living cells. Science 304:1797–1800 (10.1126/science.1099754) / Science by Y Shav-Tal (2004)
Sone M, Hayashi T, Tarui H, Agata K, Takeichi M, Nakagawa S (2007) The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons. J Cell Sci 120:2498–2506 (10.1242/jcs.009357) / J Cell Sci by M Sone (2007)
Spector DL (2003) The dynamics of chromosome organization and gene regulation. Annu Rev Biochem 72:573–608 (10.1146/annurev.biochem.72.121801.161724) / Annu Rev Biochem by DL Spector (2003)
Sprague BL, Muller F, Pego RL, Bungay PM, Stavreva DA, McNally JG (2006) Analysis of binding at a single spatially localized cluster of binding sites by fluorescence recovery after photobleaching. Biophys J 91:1169–1191 (10.1529/biophysj.105.073676) / Biophys J by BL Sprague (2006)
Tsai RY, McKay RD (2005) A multistep, GTP-driven mechanism controlling the dynamic coupling of nucleostemin. J Cell Biol 168:179–184 (10.1083/jcb.200409053) / J Cell Biol by RY Tsai (2005)

Dates

Type	When
Created	17 years, 9 months ago (Nov. 9, 2007, 5:09 a.m.)
Deposited	3 years, 11 months ago (Aug. 31, 2021, 3:30 p.m.)
Indexed	3 months, 1 week ago (May 21, 2025, 1:26 p.m.)
Issued	17 years, 9 months ago (Nov. 10, 2007)
Published	17 years, 9 months ago (Nov. 10, 2007)
Published Online	17 years, 9 months ago (Nov. 10, 2007)
Published Print	17 years, 7 months ago (Jan. 1, 2008)

Funders 0

None

BibTeX

@article{Misteli_2007, title={Physiological importance of RNA and protein mobility in the cell nucleus}, volume={129}, ISSN={1432-119X}, url={http://dx.doi.org/10.1007/s00418-007-0355-x}, DOI={10.1007/s00418-007-0355-x}, number={1}, journal={Histochemistry and Cell Biology}, publisher={Springer Science and Business Media LLC}, author={Misteli, Tom}, year={2007}, month=nov, pages={5–11} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        5,
        21
      ]
    ],
    "date-time": "2025-05-21T17:26:28Z",
    "timestamp": 1747848388525
  },
  "reference-count": 41,
  "publisher": "Springer Science and Business Media LLC",
  "issue": "1",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2007,
            11,
            10
          ]
        ],
        "date-time": "2007-11-10T00:00:00Z",
        "timestamp": 1194652800000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://creativecommons.org/licenses/by-nc/2.0"
    },
    {
      "start": {
        "date-parts": [
          [
            2007,
            11,
            10
          ]
        ],
        "date-time": "2007-11-10T00:00:00Z",
        "timestamp": 1194652800000
      },
      "content-version": "vor",
      "delay-in-days": 0,
      "URL": "https://creativecommons.org/licenses/by-nc/2.0"
    }
  ],
  "content-domain": {
    "domain": [
      "link.springer.com"
    ],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2008,
        1
      ]
    ]
  },
  "DOI": "10.1007/s00418-007-0355-x",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2007,
        11,
        9
      ]
    ],
    "date-time": "2007-11-09T10:09:03Z",
    "timestamp": 1194602943000
  },
  "page": "5-11",
  "update-policy": "http://dx.doi.org/10.1007/springer_crossmark_policy",
  "source": "Crossref",
  "is-referenced-by-count": 84,
  "title": "Physiological importance of RNA and protein mobility in the cell nucleus",
  "prefix": "10.1007",
  "volume": "129",
  "author": [
    {
      "given": "Tom",
      "family": "Misteli",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "297",
  "published-online": {
    "date-parts": [
      [
        2007,
        11,
        10
      ]
    ]
  },
  "reference": [
    {
      "key": "355_CR1",
      "doi-asserted-by": "publisher",
      "first-page": "77",
      "DOI": "10.1038/nature03207",
      "volume": "433",
      "author": "JS Andersen",
      "year": "2005",
      "unstructured": "Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005) Nucleolar proteome dynamics. Nature 433:77\u201383",
      "journal-title": "Nature"
    },
    {
      "key": "355_CR2",
      "doi-asserted-by": "publisher",
      "first-page": "369",
      "DOI": "10.1146/annurev.genom.7.080505.115732",
      "volume": "7",
      "author": "B Burke",
      "year": "2006",
      "unstructured": "Burke B, Stewart CL (2006) The laminopathies: the functional architecture of the nucleus and its contribution to disease. Annu Rev Genomics Hum Genet 7:369\u2013405",
      "journal-title": "Annu Rev Genomics Hum Genet"
    },
    {
      "key": "355_CR3",
      "doi-asserted-by": "publisher",
      "first-page": "298",
      "DOI": "10.1016/j.jtbi.2005.07.019",
      "volume": "239",
      "author": "G Carrero",
      "year": "2006",
      "unstructured": "Carrero G, Hendzel MJ, de Vries G (2006) Modelling the compartmentalization of splicing factors. J Theor Biol 239:298\u2013312",
      "journal-title": "J Theor Biol"
    },
    {
      "key": "355_CR4",
      "doi-asserted-by": "publisher",
      "first-page": "1623",
      "DOI": "10.1126/science.1076164",
      "volume": "298",
      "author": "M Dundr",
      "year": "2002",
      "unstructured": "Dundr M, Hoffmann-Rohrer U, Hu Q, Grummt I, Rothblum LI, Phair RD, Misteli T (2002) A kinetic framework for a mammalian RNA polymerase in vivo. Science 298:1623\u20131626",
      "journal-title": "Science"
    },
    {
      "key": "355_CR5",
      "doi-asserted-by": "publisher",
      "first-page": "831",
      "DOI": "10.1083/jcb.200311121",
      "volume": "164",
      "author": "M Dundr",
      "year": "2004",
      "unstructured": "Dundr M, Hebert MD, Karpova TS, Stanek D, Xu H, Shpargel KB, Meier UT, Neugebauer KM, Matera AG, Misteli T (2004) In vivo kinetics of Cajal body components. J Cell Biol 164:831\u2013842",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "355_CR6",
      "doi-asserted-by": "publisher",
      "first-page": "217",
      "DOI": "10.1007/s00418-005-0752-y",
      "volume": "123",
      "author": "SM G\u00f6risch",
      "year": "2005",
      "unstructured": "G\u00f6risch SM, Lichter P, Rippe K (2005) Mobility of multi-subunit complexes in the nucleus: accessibility and dynamics of chromatin subcompartments. Histochem Cell Biol 123:217\u2013228",
      "journal-title": "Histochem Cell Biol"
    },
    {
      "key": "355_CR7",
      "doi-asserted-by": "publisher",
      "first-page": "284",
      "DOI": "10.1016/j.ceb.2006.03.002",
      "volume": "18",
      "author": "SA Gorski",
      "year": "2006",
      "unstructured": "Gorski SA, Dundr M, Misteli T (2006) The road much traveled: trafficking in the cell nucleus. Curr Opin Cell Biol 18:284\u2013290",
      "journal-title": "Curr Opin Cell Biol"
    },
    {
      "key": "355_CR8",
      "doi-asserted-by": "publisher",
      "first-page": "21",
      "DOI": "10.1038/nrm1550",
      "volume": "6",
      "author": "Y Gruenbaum",
      "year": "2005",
      "unstructured": "Gruenbaum Y, Margalit A, Goldman RD, Shumaker DK, Wilson KL (2005) The nuclear lamina comes of age. Nat Rev Mol Cell Biol 6:21\u201331",
      "journal-title": "Nat Rev Mol Cell Biol"
    },
    {
      "key": "355_CR9",
      "doi-asserted-by": "publisher",
      "first-page": "19",
      "DOI": "10.1016/j.tcb.2005.11.005",
      "volume": "16",
      "author": "KE Handwerger",
      "year": "2006",
      "unstructured": "Handwerger KE, Gall JG (2006) Subnuclear organelles: new insights into form and function. Trends Cell Biol 16:19\u201326",
      "journal-title": "Trends Cell Biol"
    },
    {
      "key": "355_CR10",
      "doi-asserted-by": "publisher",
      "first-page": "914",
      "DOI": "10.1038/sj.embor.7401075",
      "volume": "8",
      "author": "S Heessen",
      "year": "2007",
      "unstructured": "Heessen S, Fornerod M (2007) The inner nuclear envelope as a transcription factor resting place. EMBO Rep 8:914\u2013919",
      "journal-title": "EMBO Rep"
    },
    {
      "key": "355_CR11",
      "doi-asserted-by": "publisher",
      "first-page": "135",
      "DOI": "10.1007/s00418-006-0212-3",
      "volume": "126",
      "author": "D Hernandez-Verdun",
      "year": "2006",
      "unstructured": "Hernandez-Verdun D (2006) The nucleolus: a model for the organization of nuclear functions. Histochem Cell Biol 126:135\u2013148",
      "journal-title": "Histochem Cell Biol"
    },
    {
      "key": "355_CR12",
      "doi-asserted-by": "publisher",
      "first-page": "958",
      "DOI": "10.1126/science.284.5416.958",
      "volume": "284",
      "author": "AB Houtsmuller",
      "year": "1999",
      "unstructured": "Houtsmuller AB, Rademakers S, Nigg AL, Hoogstraten D, Hoeijmakers JH, Vermeulen W (1999) Action of DNA repair endonuclease ERCC1/XPF in living cells. Science 284:958\u2013961",
      "journal-title": "Science"
    },
    {
      "key": "355_CR13",
      "doi-asserted-by": "publisher",
      "first-page": "877",
      "DOI": "10.1083/jcb.126.4.877",
      "volume": "126",
      "author": "S Huang",
      "year": "1994",
      "unstructured": "Huang S, Deerinck MH, Ellisman MH, Spector DL (1994) In vivo analysis of the stability and transport of nuclear poly(A)+ RNA. J Cell Biol 126:877\u2013899",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "355_CR14",
      "doi-asserted-by": "crossref",
      "first-page": "2407",
      "DOI": "10.1091/mbc.8.12.2407",
      "volume": "8",
      "author": "S Imai",
      "year": "1997",
      "unstructured": "Imai S, Nishibayashi S, Takao K, Tomifuji M, Fujino T, Hasegawa M, Takano T (1997) Dissociation of Oct-1 from the nuclear peripheral structure induces the cellular aging-associated collagenase gene expression. Mol Biol Cell 8:2407\u20132419",
      "journal-title": "Mol Biol Cell"
    },
    {
      "key": "355_CR15",
      "doi-asserted-by": "publisher",
      "first-page": "307",
      "DOI": "10.1101/gad.349506",
      "volume": "20",
      "author": "C Ivorra",
      "year": "2006",
      "unstructured": "Ivorra C, Kubicek M, Gonzalez JM, Sanz-Gonzalez SM, Alvarez-Barrientos A, O\u2019Connor JE, Burke B, Andres V (2006) A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C. Genes Dev 20:307\u2013320",
      "journal-title": "Genes Dev"
    },
    {
      "key": "355_CR16",
      "doi-asserted-by": "publisher",
      "first-page": "47",
      "DOI": "10.1016/0092-8674(93)90159-N",
      "volume": "73",
      "author": "LF Jim\u00e9nez-Garc\u00eda",
      "year": "1993",
      "unstructured": "Jim\u00e9nez-Garc\u00eda LF, Spector DL (1993) In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism. Cell 73:47\u201359",
      "journal-title": "Cell"
    },
    {
      "key": "355_CR17",
      "doi-asserted-by": "publisher",
      "first-page": "9677",
      "DOI": "10.1073/pnas.0403250101",
      "volume": "101",
      "author": "BR Johnson",
      "year": "2004",
      "unstructured": "Johnson BR, Nitta RT, Frock RL, Mounkes L, Barbie DA, Stewart CL, Harlow E, Kennedy BK (2004) A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation. Proc Natl Acad Sci USA 101:9677\u20139682",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "355_CR18",
      "doi-asserted-by": "publisher",
      "first-page": "10742",
      "DOI": "10.1158/0008-5472.CAN-05-2038",
      "volume": "65",
      "author": "RA Kay",
      "year": "2005",
      "unstructured": "Kay RA, Ellis IR, Jones SJ, Perrier S, Florence MM, Schor AM, Schor SL (2005) The expression of migration stimulating factor, a potent oncofetal cytokine, is uniquely controlled by 3\u2032-untranslated region-dependent nuclear sequestration of its precursor messenger RNA. Cancer Res 65:10742\u201310749",
      "journal-title": "Cancer Res"
    },
    {
      "key": "355_CR19",
      "doi-asserted-by": "publisher",
      "first-page": "41",
      "DOI": "10.1083/jcb.150.1.41",
      "volume": "150",
      "author": "MJ Kruhlak",
      "year": "2000",
      "unstructured": "Kruhlak MJ, Lever MA, Fischle W, Verdin E, Bazett-Jones DP, Hendzel MJ (2000) Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments. J Cell Biol 150:41\u201351",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "355_CR20",
      "doi-asserted-by": "publisher",
      "first-page": "R825",
      "DOI": "10.1016/j.cub.2003.10.012",
      "volume": "13",
      "author": "AI Lamond",
      "year": "2003",
      "unstructured": "Lamond AI, Sleeman JE (2003) Nuclear substructure and dynamics. Curr Biol 13:R825\u2013R828",
      "journal-title": "Curr Biol"
    },
    {
      "key": "355_CR21",
      "doi-asserted-by": "publisher",
      "first-page": "104",
      "DOI": "10.1038/nrg2041",
      "volume": "8",
      "author": "C Lanctot",
      "year": "2007",
      "unstructured": "Lanctot C, Cheutin T, Cremer M, Cavalli G, Cremer T (2007) Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions. Nat Rev Genet 8:104\u2013115",
      "journal-title": "Nat Rev Genet"
    },
    {
      "key": "355_CR22",
      "doi-asserted-by": "publisher",
      "first-page": "1131",
      "DOI": "10.1038/ncb1633",
      "volume": "9",
      "author": "DM Martindill",
      "year": "2007",
      "unstructured": "Martindill DM, Risebro CA, Smart N, Franco-Viseras Mdel M, Rosario CO, Swallow CJ, Dennis JW, Riley PR (2007) Nucleolar release of Hand1 acts as a molecular switch to determine cell fate. Nat Cell Biol 9:1131\u20131141",
      "journal-title": "Nat Cell Biol"
    },
    {
      "key": "355_CR23",
      "doi-asserted-by": "publisher",
      "first-page": "1262",
      "DOI": "10.1126/science.287.5456.1262",
      "volume": "287",
      "author": "JG McNally",
      "year": "2000",
      "unstructured": "McNally JG, Muller WG, Walker D, Wolford R, Hager GL (2000) The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science 287:1262\u20131265",
      "journal-title": "Science"
    },
    {
      "key": "355_CR24",
      "doi-asserted-by": "publisher",
      "first-page": "379",
      "DOI": "10.1038/445379a",
      "volume": "445",
      "author": "KJ Meaburn",
      "year": "2007",
      "unstructured": "Meaburn KJ, Misteli T (2007) Cell biology: chromosome territories. Nature 445:379\u2013781",
      "journal-title": "Nature"
    },
    {
      "key": "355_CR25",
      "doi-asserted-by": "publisher",
      "first-page": "733",
      "DOI": "10.1083/jcb.200506030",
      "volume": "170",
      "author": "K Mekhail",
      "year": "2005",
      "unstructured": "Mekhail K, Khacho M, Carrigan A, Hache RR, Gunaratnam L, Lee S (2005) Regulation of ubiquitin ligase dynamics by the nucleolus. J Cell Biol 170:733\u2013744",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "355_CR26",
      "doi-asserted-by": "publisher",
      "first-page": "3966",
      "DOI": "10.1091/mbc.E07-03-0295",
      "volume": "18",
      "author": "K Mekhail",
      "year": "2007",
      "unstructured": "Mekhail K, Rivero-Lopez L, Al-Masri A, Brandon C, Khacho M, Lee S (2007) Identification of a common subnuclear localization signal. Mol Biol Cell 18:3966\u20133977",
      "journal-title": "Mol Biol Cell"
    },
    {
      "key": "355_CR27",
      "doi-asserted-by": "crossref",
      "unstructured": "Meng L, Zhu Q, Tsai RY (2007) Nucleolar trafficking of nucleostemin family proteins: common versus protein-specific mechanisms. Mol Cell Biol (in press)",
      "DOI": "10.1128/MCB.00635-07"
    },
    {
      "key": "355_CR28",
      "doi-asserted-by": "publisher",
      "first-page": "843",
      "DOI": "10.1126/science.291.5505.843",
      "volume": "291",
      "author": "T Misteli",
      "year": "2001",
      "unstructured": "Misteli T (2001) Protein dynamics: implications for nuclear architecture and gene expression. Science 291:843\u2013847",
      "journal-title": "Science"
    },
    {
      "key": "355_CR29",
      "doi-asserted-by": "publisher",
      "first-page": "787",
      "DOI": "10.1016/j.cell.2007.01.028",
      "volume": "128",
      "author": "T Misteli",
      "year": "2007",
      "unstructured": "Misteli T (2007) Beyond the sequence: cellular organization of genome function. Cell 128:787\u2013800",
      "journal-title": "Cell"
    },
    {
      "key": "355_CR30",
      "doi-asserted-by": "publisher",
      "first-page": "523",
      "DOI": "10.1038/387523a0",
      "volume": "387",
      "author": "T Misteli",
      "year": "1997",
      "unstructured": "Misteli T, Caceres JF, Spector DL (1997) The dynamics of a pre-mRNA splicing factor in living cells. Nature 387:523\u2013527",
      "journal-title": "Nature"
    },
    {
      "key": "355_CR31",
      "doi-asserted-by": "publisher",
      "first-page": "604",
      "DOI": "10.1038/35007077",
      "volume": "404",
      "author": "RD Phair",
      "year": "2000",
      "unstructured": "Phair RD, Misteli T (2000) High mobility of proteins in the mammalian cell nucleus. Nature 404:604\u2013609",
      "journal-title": "Nature"
    },
    {
      "key": "355_CR32",
      "doi-asserted-by": "publisher",
      "first-page": "6393",
      "DOI": "10.1128/MCB.24.14.6393-6402.2004",
      "volume": "24",
      "author": "RD Phair",
      "year": "2004",
      "unstructured": "Phair RD, Scaffidi P, Elbi C, Vecerova J, Dey A, Ozato K, Brown DT, Hager G, Bustin M, Misteli T (2004) Global nature of dynamic protein\u2013chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol 24:6393\u20136402",
      "journal-title": "Mol Cell Biol"
    },
    {
      "key": "355_CR33",
      "doi-asserted-by": "publisher",
      "first-page": "11",
      "DOI": "10.1101/gad.1484207",
      "volume": "21",
      "author": "KV Prasanth",
      "year": "2007",
      "unstructured": "Prasanth KV, Spector DL (2007) Eukaryotic regulatory RNAs: an answer to the \u2018genome complexity\u2019 conundrum. Genes Dev 21:11\u201342",
      "journal-title": "Genes Dev"
    },
    {
      "key": "355_CR34",
      "doi-asserted-by": "publisher",
      "first-page": "249",
      "DOI": "10.1016/j.cell.2005.08.033",
      "volume": "123",
      "author": "KV Prasanth",
      "year": "2005",
      "unstructured": "Prasanth KV, Prasanth SG, Xuan Z, Hearn S, Freier SM, Bennett CF, Zhang MQ, Spector DL (2005) Regulating gene expression through RNA nuclear retention. Cell 123:249\u2013263",
      "journal-title": "Cell"
    },
    {
      "key": "355_CR35",
      "doi-asserted-by": "crossref",
      "first-page": "1239",
      "DOI": "10.1091/mbc.e05-10-0952",
      "volume": "17",
      "author": "JC Ritland-Politz",
      "year": "2006",
      "unstructured": "Ritland-Politz JC, Tufft RA, Prasanth KV, Baudendistel N, Fogarty KE, Lifshitz LM, Langowski J, Spector DL, Pederson T (2006) Rapid, diffusional shuttling of poly(A)-RNA between nuclear speckles and the nucleoplasm. Mol Cell Biol 17:1239\u20131249",
      "journal-title": "Mol Cell Biol"
    },
    {
      "key": "355_CR36",
      "doi-asserted-by": "publisher",
      "first-page": "131",
      "DOI": "10.1083/jcb.138.1.131",
      "volume": "138",
      "author": "O Seksek",
      "year": "1997",
      "unstructured": "Seksek O, Biwersi J, Verkman AS (1997) Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus. J Cell Biol 138:131\u2013142",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "355_CR37",
      "doi-asserted-by": "publisher",
      "first-page": "1797",
      "DOI": "10.1126/science.1099754",
      "volume": "304",
      "author": "Y Shav-Tal",
      "year": "2004",
      "unstructured": "Shav-Tal Y, Darzacq X, Shenoy SM, Fusco D, Janicki SM, Spector DL, Singer RH (2004) Dynamics of single mRNPs in nuclei of living cells. Science 304:1797\u20131800",
      "journal-title": "Science"
    },
    {
      "key": "355_CR38",
      "doi-asserted-by": "publisher",
      "first-page": "2498",
      "DOI": "10.1242/jcs.009357",
      "volume": "120",
      "author": "M Sone",
      "year": "2007",
      "unstructured": "Sone M, Hayashi T, Tarui H, Agata K, Takeichi M, Nakagawa S (2007) The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons. J Cell Sci 120:2498\u20132506",
      "journal-title": "J Cell Sci"
    },
    {
      "key": "355_CR39",
      "doi-asserted-by": "publisher",
      "first-page": "573",
      "DOI": "10.1146/annurev.biochem.72.121801.161724",
      "volume": "72",
      "author": "DL Spector",
      "year": "2003",
      "unstructured": "Spector DL (2003) The dynamics of chromosome organization and gene regulation. Annu Rev Biochem 72:573\u2013608",
      "journal-title": "Annu Rev Biochem"
    },
    {
      "key": "355_CR40",
      "doi-asserted-by": "publisher",
      "first-page": "1169",
      "DOI": "10.1529/biophysj.105.073676",
      "volume": "91",
      "author": "BL Sprague",
      "year": "2006",
      "unstructured": "Sprague BL, Muller F, Pego RL, Bungay PM, Stavreva DA, McNally JG (2006) Analysis of binding at a single spatially localized cluster of binding sites by fluorescence recovery after photobleaching. Biophys J 91:1169\u20131191",
      "journal-title": "Biophys J"
    },
    {
      "key": "355_CR41",
      "doi-asserted-by": "publisher",
      "first-page": "179",
      "DOI": "10.1083/jcb.200409053",
      "volume": "168",
      "author": "RY Tsai",
      "year": "2005",
      "unstructured": "Tsai RY, McKay RD (2005) A multistep, GTP-driven mechanism controlling the dynamic coupling of nucleostemin. J Cell Biol 168:179\u2013184",
      "journal-title": "J Cell Biol"
    }
  ],
  "container-title": "Histochemistry and Cell Biology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://link.springer.com/content/pdf/10.1007/s00418-007-0355-x.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://link.springer.com/article/10.1007/s00418-007-0355-x/fulltext.html",
      "content-type": "text/html",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://link.springer.com/content/pdf/10.1007/s00418-007-0355-x.pdf",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    },
    {
      "URL": "https://link.springer.com/content/pdf/10.1007/s00418-007-0355-x.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        8,
        31
      ]
    ],
    "date-time": "2021-08-31T19:30:47Z",
    "timestamp": 1630438247000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://link.springer.com/10.1007/s00418-007-0355-x"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2007,
        11,
        10
      ]
    ]
  },
  "references-count": 41,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          2008,
          1
        ]
      ]
    }
  },
  "alternative-id": [
    "355"
  ],
  "URL": "http://dx.doi.org/10.1007/s00418-007-0355-x",
  "relation": {},
  "ISSN": [
    "0948-6143",
    "1432-119X"
  ],
  "subject": [],
  "container-title-short": "Histochem Cell Biol",
  "published": {
    "date-parts": [
      [
        2007,
        11,
        10
      ]
    ]
  },
  "assertion": [
    {
      "value": "27 October 2007",
      "order": 1,
      "name": "accepted",
      "label": "Accepted",
      "group": {
        "name": "ArticleHistory",
        "label": "Article History"
      }
    },
    {
      "value": "10 November 2007",
      "order": 2,
      "name": "first_online",
      "label": "First Online",
      "group": {
        "name": "ArticleHistory",
        "label": "Article History"
      }
    }
  ]
}