DOI: 10.1007/bf02535447. Influence of elaidate and erucate on heart mitochondria

Influence of elaidate and erucate on heart mitochondria

10.1007/bf02535447

Crossref journal-article

Wiley

Lipids (311)

Abstract

AbstractMale, weanling rats were fed, for up to six weeks, corn oil (CO), rapeseed oil (RSO), partially hydrogenated fat (HF), or a mixture of partially hydrogenated fat and corn oil (HF+CO). The respiratory activity of their isolated heart mitochondria, their hormone‐sensitive lipase activity, and the fatty acid compositions of the phospholipids of the mitochondria were determined. The results indicated that heart mitochondria isolated from rats which had been fed corn oil (CO) had a higher rate of oxygen uptake, showed higher respiratory control ratios, higher ADP/0 ratios and a higher rate of ATP synthesis than the heart mitochondria isolated from those fed rapeseed oil or hydrogenated fats. The oxygen uptake rates of the rat heart mitochondria isolated from each dietary group of rats was in order: oleyl carnitine ≫ erucyl carnitine > elaidyl carnitine. The decreased capacity to oxidize substrate by heart mitochondria which had been isolated from the hearts of rats fed rapeseed or hydrogenated soybean oil as compared with those fed corn oil as a sole source of dietary fat seemed related to the mitochondria lipid composition. The type of dietary fat fed had a pronounced influence on the mitochondrial fatty acid compositions of phosphatidylcholine, phosphatidylethanolamine, and cardiolipin. The lipase activity of the RSO‐fed group did not show any increment with either epinephrine or supplemental ATP treatment. The substrate preference for lipase activity in myocardium was corn oil‐triglycerides > trierucin > trielaidin > tripalmitin. However, cardiac lipid accumulation did not seem related to lipase activity in the myocardium.

Bibliography

Lee Hsu, C. M., & Kummerow, F. A. (1977). Influence of elaidate and erucate on heart mitochondria. Lipids, 12(6), 486â494. Portico.

Authors 2

Chi Ming Lee Hsu (first)
Fred A. Kummerow (additional)

References 39 Referenced 63

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{'key': 'e_1_2_1_4_1', 'first-page': '296', 'volume': '12', 'author': 'Abdellatif A.M.M.', 'year': '1970', 'journal-title': 'Ibid.'} / Ibid. by Abdellatif A.M.M. (1970)
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{'key': 'e_1_2_1_7_1', 'first-page': '13', 'volume': '337', 'author': 'Swarttouw M.A.', 'year': '1974', 'journal-title': 'Ibid.'} / Ibid. by Swarttouw M.A. (1974)
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{'key': 'e_1_2_1_23_1', 'volume-title': 'Methods in Enzymology', 'author': 'Shipski V.P.', 'year': '1969'} / Methods in Enzymology by Shipski V.P. (1969)
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{'key': 'e_1_2_1_38_1', 'first-page': '1', 'volume-title': 'Am. Heart Assoc. Monograph No. 48', 'author': 'Trump B.F.', 'year': '1976'} / Am. Heart Assoc. Monograph No. 48 by Trump B.F. (1976)
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Dates

Type	When
Created	18 years, 9 months ago (Dec. 5, 2006, 1:34 a.m.)
Deposited	1 year, 11 months ago (Sept. 28, 2023, 9:03 p.m.)
Indexed	1 day, 15 hours ago (Sept. 4, 2025, 9:55 a.m.)
Issued	48 years, 3 months ago (June 1, 1977)
Published	48 years, 3 months ago (June 1, 1977)
Published Online	48 years, 3 months ago (June 1, 1977)
Published Print	48 years, 3 months ago (June 1, 1977)

Funders 0

None

BibTeX

@article{Lee_Hsu_1977, title={Influence of elaidate and erucate on heart mitochondria}, volume={12}, ISSN={1558-9307}, url={http://dx.doi.org/10.1007/bf02535447}, DOI={10.1007/bf02535447}, number={6}, journal={Lipids}, publisher={Wiley}, author={Lee Hsu, Chi Ming and Kummerow, Fred A.}, year={1977}, month=jun, pages={486–494} }

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