DOI: 10.1007/bf02534429. Distribution of glycosphingolipids of monkey small and large intestinal mucosa

Distribution of glycosphingolipids of monkey small and large intestinal mucosa

10.1007/bf02534429

Crossref journal-article

Wiley

Lipids (311)

Abstract

AbstractThe ganglioside and neutral glycosphingolipid composition of adult monkey small and large intestinal mucosa were characterized and compared. GM3, GM2 and GD1A were found to be the principal gangliosides in each of these tissues. Dihexosylceramide was the major neutral glycosphingolipid of both organs. The total content of gangliosides and neutral glycolipids/ceramide, however, was ca. four‐fold and two‐fold higher, respectively, in small intestinal than colonic mucosa.While all glycosphingolipids examined contained hydroxy and nonhydroxy fatty acids, the former fatty acids accounted for 60–90% of the total fatty acids in both organs. Sphingosine was the predominant long chain base of ceramide, mono‐, di‐, tri‐ and tetrahexosylceramide, whereas phytosphingosine was the major base of GM3 in both tissues. The results of these studies demonstrate that while many similarities of monkey small and large intestinal glycosphingolipids exist, qualitative and quantitative differences are present along the length of the monkey gut. These differences may be at least partially responsible for certain of the well‐recognized variations in normal physiological and pathological processes that occur in these organs.

Bibliography

Dahiya, R., Brown, M. D., & Brasitus, T. A. (1986). Distribution of glycosphingolipids of monkey small and large intestinal mucosa. Lipids, 21(2), 107â111. Portico.

Authors 3

Rajvir Dahiya (first)
Michael D. Brown (additional)
Thomas A. Brasitus (additional)

References 37 Referenced 9

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Dates

Type	When
Created	18 years, 9 months ago (Nov. 29, 2006, 12:20 a.m.)
Deposited	1 year, 11 months ago (Sept. 28, 2023, 11 a.m.)
Indexed	1 year, 7 months ago (Jan. 13, 2024, 12:28 a.m.)
Issued	39 years, 6 months ago (Feb. 1, 1986)
Published	39 years, 6 months ago (Feb. 1, 1986)
Published Online	39 years, 6 months ago (Feb. 1, 1986)
Published Print	39 years, 6 months ago (Feb. 1, 1986)

Funders 0

None

BibTeX

@article{Dahiya_1986, title={Distribution of glycosphingolipids of monkey small and large intestinal mucosa}, volume={21}, ISSN={1558-9307}, url={http://dx.doi.org/10.1007/bf02534429}, DOI={10.1007/bf02534429}, number={2}, journal={Lipids}, publisher={Wiley}, author={Dahiya, Rajvir and Brown, Michael D. and Brasitus, Thomas A.}, year={1986}, month=feb, pages={107–111} }

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