Analysis of nucleolar transcription and processing domains and pre-rRNA movements by in situ hybridization
10.1007/bf02510485
Crossref journal-article
Springer Science and Business Media LLC
Chromosoma (297)
Bibliography

Lazdins, I. B., Delannoy, M., & Sollner-Webb, B. (1997). Analysis of nucleolar transcription and processing domains and pre-rRNA movements by in situ hybridization. Chromosoma, 105(7–8), 481–495.

Authors 3
  1. Inara B. Lazdins (first)
  2. Michael Delannoy (additional)
  3. Barbara Sollner-Webb (additional)
References 79 Referenced 59
  1. Beven A, Lee R, Razen M, Leader D, Nrown J, Shaw P (1966) The organization of rRNA processing correlates with the distribution of nucleolar snRNAs. J Cell Sci 109:1241–1251 (10.1242/jcs.109.6.1241) / J Cell Sci by A Beven (1966)
  2. Bregman DB, Du L, Zee S van der, Warren SL (1995) Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains. J Cell Biol 129:287–298 (10.1083/jcb.129.2.287) / J Cell Biol by DB Bregman (1995)
  3. Cavanaugh AH, Thompson EA (1985) Hormonal regulation of transcription of rDNA: Glucocorticoid effects upon initiation and elongation in vitro. Nucleic Acids Res 13:3357 (10.1093/nar/13.9.3357) / Nucleic Acids Res by AH Cavanaugh (1985)
  4. Cerdido A, Medina F (1995) Subnucleolar location of fibrillarin and variation in its levels during the cell cycle and during differentiation in plants. Chromosoma 103:625–634 (10.1007/BF00357689) / Chromosoma by A Cerdido (1995)
  5. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter W.J. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294–5299 (10.1021/bi00591a005) / Biochemistry by JM Chirgwin (1979)
  6. Craig N, Kass, S, Sollner-Webb B (1987) Nucleotide sequence determining the first clearage site in the processing of mouse pre-rRNA. Proc Natl Acad Sci USA 84:629–633 (10.1073/pnas.84.3.629) / Proc Natl Acad Sci USA by N Craig (1987)
  7. Chu S, Archer R, Zengel J, Lindahl L (1994) The RNA of RNase MRP is required for normal processing of ribosomal RNA. Proc Natl Acad Sci 91: 659–663 (10.1073/pnas.91.2.659) / Proc Natl Acad Sci by S Chu (1994)
  8. Derenzini M, Thiry M, Goessens G (1990) Ultrastructural cytochemistry of the mammalian cell nucleolus. J Histochem Cytochem 9: 1237–1256 (10.1177/38.9.2201735) / J Histochem Cytochem by M Derenzini (1990)
  9. Derenzini M, Farabegoli F, Trere D (1993) Localization of DNA in the fibrillar components of the nucleolus: a cytochemical and morphometric study. J Histochem Cytochem 41:829–836 (10.1177/41.6.8315275) / J Histochem Cytochem by M Derenzini (1993)
  10. Dumenco V, Wejksnora P (1986) Characterization of the region around the start point of transcription of ribosomal RNA in the Chinese hamster. Gene 46:227–235 (10.1016/0378-1119(86)90407-5) / Gene by V Dumenco (1986)
  11. Dundr M, Raska I (1993) Nonisotopic ultrastructural mapping of transcription sites within the nucleolus. Exp Cell Res 208:275–281 (10.1006/excr.1993.1247) / Exp Cell Res by M Dundr (1993)
  12. Fakan S (1978) High resolution autoradiographic sttudies on chromatin functions. Cell Nucleus 5:3–53 / Cell Nucleus by S Fakan (1978)
  13. Fischer D, Weisenberger D, Scheer U (1991) Assigning functions to nucleolar structures. Chromosoma 101:133–140 (10.1007/BF00355363) / Chromosoma by D Fischer (1991)
  14. Geuskens M, Bernhard W (1969) Cytochimie ultrastructurale du nucléole. Exp Cell Res 44:579–598 (10.1016/0014-4827(66)90462-9) / Exp Cell Res by M Geuskens (1969)
  15. Goessens G (1976) High resolution autoradiographic studies of Ehrlich tumour cell nuclei. Exp Cell Res 100:88–94 (10.1016/0014-4827(76)90330-X) / Exp Cell Res by G Goessens (1976)
  16. Goessens G (1984) Nucleolar structure. Int Rev Cytol 87:107–158 (10.1016/S0074-7696(08)62441-9) / Int Rev Cytol by G Goessens (1984)
  17. Goessens G, LePoint A (1979) The NORs: recent data and hypotheses. Biol. Cellulaire 35:211–220 / Biol. Cellulaire by G Goessens (1979)
  18. Granboulan N, Granboulan P (1965) Cytochimie ultrastructurale du nucleole. Exp Cell Res 38:604–619 (10.1016/0014-4827(65)90384-8) / Exp Cell Res by N Granboulan (1965)
  19. Grummt I (1978) In vitro synthesis of pre-rRNA in isolated nucleoli. Cell Nucleus 5:373–412 / Cell Nucleus by I Grummt (1978)
  20. Gurney T (1985) Characterization of mouse 45S ribosomal RNA subspecies suggests that the first processing cleavage occurs 600±100 nucleotides from the 5′ end and the second 500±100 nucleotides from the 3′ end of a 13.9 kb precursor. Nucleic Acids Res. 13:4905–4919 (10.1093/nar/13.13.4905) / Nucleic Acids Res by T Gurney (1985)
  21. Hadjiolov A (1985) The nucleolus and ribosome biogenesis. Springer, Berlin Heidelberg New York (10.1007/978-3-7091-8742-5) / The nucleolus and ribosome biogenesis by A Hadjiolov (1985)
  22. Harrington C, Chikaraishi D (1987) Transcription of spacer sequences flaking the rat 45S ribosomal DNA gene. Mol Cell Biol 7:314–325 (10.1128/MCB.7.1.314) / Mol Cell Biol by C Harrington (1987)
  23. Hassan AB, Errington R, White N, Jacksopn D, Cook P (1994) Replication and transcription sites are colocalized in human cells. J Cell Sci 107:425–4334 (10.1083/jcb.127.2.425) / J Cell Sci by AB Hassan (1994)
  24. Henderson S, Sollner-Webb B (1986) A transcriptional terminator is a novel element of the promoter of the mouse ribosomal RNA gene. Cell 47:891–900 (10.1016/0092-8674(86)90804-4) / Cell by S Henderson (1986)
  25. Henderson SL, Ryan K, Sollner-Webb B (1989) The promoterproximal rRNA termination augments initiation by preventing disruption of the stable transcription complex caused by polymerase read-in. Genes Dev 3:212–223 (10.1101/gad.3.2.212) / Genes Dev by SL Henderson (1989)
  26. Hozak P (1995) Catching RNA polymerase I in flagranti: ribosomal genes are transcribed in the dense fibrillar component of the nucleolus. Exp Cell Res 216:285–289 (10.1006/excr.1995.1036) / Exp Cell Res by P Hozak (1995)
  27. Hozak P, Cook PR, Schofer C, Mosgoller W, Wachtler F (1994) Sites of transcription of ribosomal RNA and intranucleolar structure in HeLa cells. J Cell Sci 107:639–648 (10.1242/jcs.107.2.639) / J Cell Sci by P Hozak (1994)
  28. Hughes J (1996) Functional base pairing interaction between highly conserved elements of U3 small nucleolar RNA and the small ribosomal subunit. J Mol Biol 259:645–654 (10.1006/jmbi.1996.0346) / J Mol Biol by J Hughes (1996)
  29. Hughes J, Ares M (1991) Depletion of U3 small nucleolar RNA inhibits cleavage in the 5′ external transcribed spacer of yeast pre-rRNA and impairs formation of 18S rRNA. EMBO J 10:4231–4239 (10.1002/j.1460-2075.1991.tb05001.x) / EMBO J by J Hughes (1991)
  30. Hugle B, Hazen R, Scheer U, Franke W (1985) Localization of ribosomal protein S1 in the GC of the interphase nucleolus and its distribution during mitosis. J Cell Bio 100:873–886 (10.1083/jcb.100.3.873) / J Cell Bio by B Hugle (1985)
  31. Jackson DA, Hassan AB, Errington RJ, Cook PR (1993) Visualization of focal sites of transcription within human nuclei. EMBO J 12:1059–1065 (10.1002/j.1460-2075.1993.tb05747.x) / EMBO J by DA Jackson (1993)
  32. Johnson CV, Singer RH, Lawrence JB (1991) Fluorescent detection of nuclear RNA and DNA: Implication for genome organization. Methods Cell Biol 35:73–99 (10.1016/S0091-679X(08)60569-5) / Methods Cell Biol by CV Johnson (1991)
  33. Jordan E (1984) Nucleolar nomenclature. J Cell Sci 67:217–220 (10.1242/jcs.67.1.217) / J Cell Sci by E Jordan (1984)
  34. Jordan EG, Zatsepina O, Shaw P (1992) Widely dispersed DNA within plant and animal nucleoli visualized by 3-d fluorescence microscopy. Chromosoma 101:478–482 (10.1007/BF00352470) / Chromosoma by EG Jordan (1992)
  35. Kass, S, Craig N, Sollner-Webb B (1987) Primary processing of mammalian rRNA involves two adjacent cleavages and is not species specific. Mol Cell Biol 7:2891–2898 (10.1128/MCB.7.8.2891) / Mol Cell Biol by S Kass (1987)
  36. Kass, S, Tyc K, Steitz J, Sollner-Webb B (1990) The U3 small nucleolar ribonucleoprotein functions in the first step of pre-ribosomal RNA processing. Cell 60:897–908 (10.1016/0092-8674(90)90338-F) / Cell by S Kass (1990)
  37. Labhart P, Reeder R (1987) Heat shock stabilizes the highly unstable transcripts of theXenopus ribosomal gene spacer. Proc Nat Acad Sci USA 84:56–60 (10.1073/pnas.84.1.56) / Proc Nat Acad Sci USA by P Labhart (1987)
  38. Lampert A, Feigelson P (1974) A short lived polypeptide component of one of two discrete functional pools of hepatic nuclear alpha-amanitin resistant RNA polymerases. Biochem Biophys Res Comm 58:1030–1038 (10.1016/S0006-291X(74)80247-0) / Biochem Biophys Res Comm by A Lampert (1974)
  39. Lawrence J, Singer R, McNeil J (1990) Interphase and metaphase resolution of different distances within the human dystrophin gene. Science 249:928–932 (10.1126/science.2203143) / Science by J Lawrence (1990)
  40. Masson C, Bounoli C, Fompriox N, Szollosi M, Debey P, Hermandez-Verdun D (1996) Conditions favoring RNA polymerase I transcription in permeabilized cells. Exp Cell Res 226:114–125 (10.1006/excr.1996.0209) / Exp Cell Res by C Masson (1996)
  41. Matera G, Tycowski K, Steitz J, Ward D (1994) Organization of snoRNPs by fluorescence in situ hybridization and immunocytochemistry. Mol Biol Cell 5:1289–1299 (10.1091/mbc.5.12.1289) / Mol Biol Cell by G Matera (1994)
  42. Melese T, Xue Z (1995) The nucleolus: an organelle formed by the act of building a ribosome. Curr Opin Cell Biol 7:319–324 (10.1016/0955-0674(95)80085-9) / Curr Opin Cell Biol by T Melese (1995)
  43. Miller KG, Sollner-Webb B (1981) Transcription of mouse rRNA genes by RNA polymerase I: in vitro and in vivo initiation and processing sites. Cell 27:167–174 (10.1016/0092-8674(81)90370-6) / Cell by KG Miller (1981)
  44. Miller O Jr (1981) The nucleolus, chromosomes, and visualization of genetic activity. J Cell Biol 91:15s-21s (10.1083/jcb.91.3.15s) / J Cell Biol by O Miller Jr (1981)
  45. Miller O Jr, Beatty B (1969) Visualization of nucleolar genes. Science 164:955–957 (10.1126/science.164.3882.955) / Science by O Miller Jr (1969)
  46. Mirre C, Stahl A (1978) Peripheral RNA synthesis of fibrillar center in nucleoli if Japanese quail oocytes and somatic cells. J Ultrastruct Res 64:377–387 (10.1016/S0022-5320(78)90045-X) / J Ultrastruct Res by C Mirre (1978)
  47. Mishima Y, Mishima T, Ogata K (1985) Coupled transcription and processing of mouse rRNA in a cell-free system. EMBO J 4:3879–3886 (10.1002/j.1460-2075.1985.tb04161.x) / EMBO J by Y Mishima (1985)
  48. Miwa T, Kaminami R, Yoshikura H, Sudo K, Muramatsu M (1987) Transcription termination and RNA processing in the 3′ end spacer of mouse rRNA genes. Nuc Acids Res 15:2043–2055 (10.1093/nar/15.5.2043) / Nuc Acids Res by T Miwa (1987)
  49. Morgan G, Roan J, Baaken A, Reeder R (1984) Variations in transcriptional activity of rDNA spacer promoters. Nuc Acids Res 12:6043–6052 (10.1093/nar/12.15.6043) / Nuc Acids Res by G Morgan (1984)
  50. Morrissey J, Tollervey D (1995) Birth of the snoRNAs. TIBS 20:78–82 / TIBS by J Morrissey (1995)
  51. Mougey E, O'Rilley M, Osheim Y, Miller OJ Jr, Beyer A, Sollner-Webb B (1993) The terminal balls characteristic of eukaryotic rRNA transcription units in chromatin spreads are rRNA processing complexes. Genes Dev 7:1609–1619 (10.1101/gad.7.8.1609) / Genes Dev by E Mougey (1993)
  52. Ochs R, Lischwe M, Spohn W, Busch H (1985) Fibrillarin: a new protein in the nucleolus identified by autoimmune sera. Biol Cell 54:123–134 (10.1111/j.1768-322X.1985.tb00387.x) / Biol Cell by R Ochs (1985)
  53. Peculis B, Steitz JA (1993) Disruption of U8 nucleolar snRNA inhibits 5.8S and 28S rRNA processing in theXenopus oocyte. Cell 73:1233–1245 (10.1016/0092-8674(93)90651-6) / Cell by B Peculis (1993)
  54. Puvion E, Moyne G (1981) In situ localization of RNA structures. Cell Nucleus 8:59–115 / Cell Nucleus by E Puvion (1981)
  55. Puvion-Dutilleul F, Bachellerie J.-P, Puvion E (1991a) Nucleolar organization of HeLa cells as studied by in situ hybridization. Chromosoma 100:395–409 (10.1007/BF00337518) / Chromosoma by F Puvion-Dutilleul (1991)
  56. Puvion-Dutilleul F, Mazan S, Nicoloso M, Christensen M, Bachellerie J-P (1991b). Localization pf U3 RNA molecules in nucleoli of HeLa and mouse 3T3 cells by high resolution in situ hybridization. Eur J Cell Biol 56:178–186 / Eur J Cell Biol by F Puvion-Dutilleul (1991)
  57. Puvion-Dutilleul F, Mazan S, Nicoloso M, Pichard E, Bachellerie J-P, Puvion E (1992) Alterations of nucleolar ultrastructure and ribosome biogenesis by actinomycin D. Implications for U3 snRNP function. Eur J Cell Biol 58:149–162 / Eur J Cell Biol by F Puvion-Dutilleul (1992)
  58. Raska I, Reimer G, Jarnik M, Krostrouch Z, Raska K (1989) Does the synthesis of rRNA take place within nucleolar fibrillar centers or dense fibrillar ocomponents? Biol Cell 65:79–82 (10.1016/0248-4900(89)90013-0) / Biol Cell by I Raska (1989)
  59. Reimer G, Raska I, Scheer U, Tan E (1988) Immunolocalization of 7-2 RNP in the granular component of the nucleolus. Exp Cell Res 176:117–128 (10.1016/0014-4827(88)90126-7) / Exp Cell Res by G Reimer (1988)
  60. Roussel P, Andre CH, Masson C, Geraud G, Hernandez-Verdun D (1993) Localization of RNA polymerase I transcription factor hUBF during the cell cycle. J Cell Sci 104:327–337 (10.1242/jcs.104.2.327) / J Cell Sci by P Roussel (1993)
  61. Royal A, Simard R (1975) RNA synthesis in the ultrastructural and biochemical components of the nucleolus of CHO cells. J Cell Biol 66:577–585 (10.1083/jcb.66.3.577) / J Cell Biol by A Royal (1975)
  62. Savino R, Gerbi SA (1990) In vivo disruption ofXenopus U3 snRNA affects ribosomal RNA processing. EMBO J 9:2291–2308 (10.1002/j.1460-2075.1990.tb07401.x) / EMBO J by R Savino (1990)
  63. Schedle A, Willheim M, Zeitelberger A, Gessl A, Frauendorfer K, Schofer C, Wachtler F (1992) Nucleolar morphology and rDNA in situ hubridization in monocytes. Cell Tissue Res 269:473–480 (10.1007/BF00353902) / Cell Tissue Res by A Schedle (1992)
  64. Scheer U, Rose KM (1984) Localization of RNA polymerase I in nterphase cells and mitotic chromosomes by light and electron microscopic immunocytochemistry. Proc Natl Acad Sci USA 81:1431–1435 (10.1073/pnas.81.5.1431) / Proc Natl Acad Sci USA by U Scheer (1984)
  65. Scheer U, Weisenberger D (1994) The nucleolus Curr Opin Cell Biol 6:354–359 (10.1016/0955-0674(94)90026-4) / Curr Opin Cell Biol by U Scheer (1994)
  66. Scheer U, Thiry M, Goessens G (1993) Structure, function and assembly of the nucleolus. Trends Cell Biol 3:236–241 (10.1016/0962-8924(93)90123-I) / Trends Cell Biol by U Scheer (1993)
  67. Schmitt M, Clayton D (1993) Nuclear RNase MRP is required for correct processing of pre-5.8S rRNA inSaccharomyces cerevisiae. Mol Cell Biol 13:7935–7941 (10.1128/MCB.13.12.7935) / Mol Cell Biol by M Schmitt (1993)
  68. Schofer C, Muller M, Leitner M, Wachtler F (1993) The uptake of uridine in the nucleolus occurs in the dense fibrillar component. Cytogenet Cell Genet 64:27–30 (10.1159/000133553) / Cytogenet Cell Genet by C Schofer (1993)
  69. Shaw PJ, Highett MI, Beven AF, Jordan EG (1995) The nucleolar architecture of polymerase I transcription and processing. EMBO J 14:2896–2906 (10.1002/j.1460-2075.1995.tb07289.x) / EMBO J by PJ Shaw (1995)
  70. Sisodia SS, Sollner-Webb B, Cleveland DW (1987) Specificity of RNA maturation pathways: RNAs transcribed by RNA polymerase III are not substrates for splicing or polyadenylation. Mol Cell Biol 7:3602–3612 (10.1128/MCB.7.10.3602) / Mol Cell Biol by SS Sisodia (1987)
  71. Sollner-Webb B, Tyc K, Steitz J (1996) Ribosomal RNA processing in eukaryotes. In: Zimmerman R, Dahlberg A (eds) Ribosomal RNA: Structure, Evolution, Processing and Function in Protein Synthesis. CRC Press, pp. 469–490
  72. Strouboulis I, Wolffe A (1996) Functional complementation of the nucleolus. J Cell Sci 109:1991–2000 (10.1242/jcs.109.8.1991) / J Cell Sci by I Strouboulis (1996)
  73. Thiry M (1992) New data concernig the functional organization of the mammalian cell nucleolus: detection of RNA and rRNA by in situ molecular immunocytochemistry. Nuc Acids Res 20:6195–6200 (10.1093/nar/20.23.6195) / Nuc Acids Res by M Thiry (1992)
  74. Thiry M (1993) Ultrastructural distribution of DNA and RNA within the nucleolus of human Sertoli cells as seen by molecular immunocytochemistry. J Cell Sci 105:33–39 (10.1242/jcs.105.1.33) / J Cell Sci by M Thiry (1993)
  75. Thiry M, Goessens G (1991) Distinguishing the sites of pre-rRNA synthesis and accumulation in Ehrlich tumor cell nucleoli. J Cell Sci 99:759–767 (10.1242/jcs.99.4.759) / J Cell Sci by M Thiry (1991)
  76. Tower J, Henderson S, Dougherty C, Wejksnora P, Sollner-Webb B (1989) An RNA polymerase I promoter located in the CHO and mouse rDNA spacers. Mol Cell Biol 9:1513–1525 (10.1128/MCB.9.4.1513) / Mol Cell Biol by J Tower (1989)
  77. Trendelenburg M (1981) Initiations of transcription at distinct promoter sites in spacer regions between pre-rRNA genes in oocytes ofX. laevis. Biol Cell 42:1–12 / Biol Cell by M Trendelenburg (1981)
  78. Wachtler F, Schofer C, Schedle A, Schwarzacher H, Hartung M, Stahl A, Gonzales I, Sylvester J (1991) Transcribed and non-transcribed parts of the human ribosomal gene repeat show a similar distribution in nucleoli. Cytogenet Cell Res 57:175–178 (10.1159/000133140) / Cytogenet Cell Res by F Wachtler (1991)
  79. Weisenberger D, Scheer U (1995) A possible mechanism for the inhibition of rRNA gene transcription during mitosis. J Cell Biol 129:561–575 (10.1083/jcb.129.3.561) / J Cell Biol by D Weisenberger (1995)
Dates
Type When
Created 18 years, 10 months ago (Oct. 10, 2006, 10:51 p.m.)
Deposited 4 years ago (Aug. 1, 2021, 9:09 p.m.)
Indexed 1 month, 2 weeks ago (July 11, 2025, 6:32 a.m.)
Issued 28 years, 2 months ago (June 1, 1997)
Published 28 years, 2 months ago (June 1, 1997)
Published Print 28 years, 2 months ago (June 1, 1997)
Funders 0

None

@article{Lazdins_1997, title={Analysis of nucleolar transcription and processing domains and pre-rRNA movements by in situ hybridization}, volume={105}, ISSN={1432-0886}, url={http://dx.doi.org/10.1007/bf02510485}, DOI={10.1007/bf02510485}, number={7–8}, journal={Chromosoma}, publisher={Springer Science and Business Media LLC}, author={Lazdins, Inara B. and Delannoy, Michael and Sollner-Webb, Barbara}, year={1997}, month=jun, pages={481–495} }