On the evolution of Tn21-like multiresistance transposons: Sequence analysis of the gene (aacC1) for gentamicin acetyltransferase-3-I(AAC(3)-I), another member of the Tn21-based expression cassette
10.1007/bf02464882
Crossref journal-article
Springer Science and Business Media LLC
Molecular and General Genetics MGG (297)
Bibliography

Wohlleben, W., Arnold, W., Bissonnette, L., Pelletier, A., Tanguay, A., Roy, P. H., Gamboa, G. C., Barry, G. F., Aubert, E., Davies, J., & Kagan, S. A. (1989). On the evolution of Tn21-like multiresistance transposons: Sequence analysis of the gene (aacC1) for gentamicin acetyltransferase-3-I(AAC(3)-I), another member of the Tn21-based expression cassette. Molecular and General Genetics MGG, 217(2–3), 202–208.

Authors 11
  1. Wolfgang Wohlleben (first)
  2. Walter Arnold (additional)
  3. Luc Bissonnette (additional)
  4. Alex Pelletier (additional)
  5. Annie Tanguay (additional)
  6. Paul H. Roy (additional)
  7. Gary C. Gamboa (additional)
  8. Gerard F. Barry (additional)
  9. Elisabeth Aubert (additional)
  10. Julian Davies (additional)
  11. Sarah A. Kagan (additional)
References 50 Referenced 121
  1. Allmansberger R, Bräu B, Piepersberg W (1985) Genes for gentamicin-(3)-N-acetyl-transferases III and IV: II. Nucleotide sequences of three AAC(3)-III genes and evolutionary aspects. Mol Gen Genet 198:514–520 (10.1007/BF00332949) / Mol Gen Genet by R Allmansberger (1985)
  2. Bräu B, Pilz U, Piepersberg W (1984) Genes for gentamicin-(3)-N-acetyltransferases III and IV. I. Nucleotide sequence of the AAC(3)-IV gene and possible involvement of an IS140 element in its expression. Mol Gen Genet 193:179–187 (10.1007/BF00327434) / Mol Gen Genet by B Bräu (1984)
  3. Brzezniska M, Benveniste R, Davies J, Daniels PJL, Weinstein J (1972) Gentamicin resistance in strains ofPseudomonas aeruginosa mediated by enzymatic N-acetylation of the 2-deoxystreptamine moiety. Biochemistry 11:761–766 (10.1021/bi00755a013) / Biochemistry by M Brzezniska (1972)
  4. Cameron FH, Groot Obbink DJ., Ackerman VP, Hall RM (1986) Nucleotide sequence of the AAD(2″) aminoglycoside adenylyltransferase determinantaadB. Evolutionary relationship of this region with those surroundingaadA in R538-1 anddhfrII in R388. Nucleic Acids Res 14:8625–8635 (10.1093/nar/14.21.8625) / Nucleic Acids Res by FH Cameron (1986)
  5. Chinault AC, Blakesley VA, Roessler E, Willis DG, Smith CA, Cook RG, Fenwick RG jr (1986) Characterisation of transferable plasmids fromShigella flexneri 2a that confer resistance to trimethoprim, streptomycin, and sulfonamides. Plasmid 15:119–131 (10.1016/0147-619X(86)90048-X) / Plasmid by AC Chinault (1986)
  6. Davies J (1986a) A new look at antibiotic resistance. FEMS Microbiol Revs 39:363–371 (10.1111/j.1574-6968.1986.tb01866.x) / FEMS Microbiol Revs by J Davies (1986)
  7. Davies JE (1986b) Aminoglycoside-aminocyclitol antibiotics and their modifying enzymes. In: Antibiotics in laboratory medicine, Second edition. Williams & Wilkins, Baltimore, pp 790–809 / Antibiotics in laboratory medicine by JE Davies (1986)
  8. Davies J, Smith DI (1978) Plasmid determined resistance to antimicrobial agents. Annu Rev Microbiol 32:469–518 (10.1146/annurev.mi.32.100178.002345) / Annu Rev Microbiol by J Davies (1978)
  9. De la Cruz F, Grinsted J (1982) Genetic and molecular characterisation of Tn21, a multiple resistance transposon from R100-1. J Bacteriol 151:222–228 (10.1128/JB.151.1.222-228.1982) / J Bacteriol by F Cruz De la (1982)
  10. Dowding J, Davies J (1975) Mechanisms and origins of plasmid-determined antibiotic resistance. Microbiology 1974. American Soc Microbiol, Washington DC, pp 179–186 / Mechanisms and origins of plasmid-determined antibiotic resistance / Microbiology 1974 by J Dowding (1975)
  11. Flensburg J, Steen R (1986) Nucleotide sequence analysis of the trimethoprim resistant dihydrofolate reductase encoded by R plasmid R751. Nucleic Acids Res 14:5933 (10.1093/nar/14.14.5933) / Nucleic Acids Res by J Flensburg (1986)
  12. Fling ME, Kopf J, Richards C (1985) Nucleotide sequence of the transposon Tn7 gene encoding an aminoglycoside-modifying enzyme, 3″(9)-O-nucleotidyltransferase. Nucleic Acids Res 13:7095–7106 (10.1093/nar/13.19.7095) / Nucleic Acids Res by ME Fling (1985)
  13. Haas MJ, Dowding JE (1975) Aminoglycoside-modifying enzymes. Methods Enzymol 43:611–640 (10.1016/0076-6879(75)43124-X) / Methods Enzymol by MJ Haas (1975)
  14. Hall RM, Vockler C (1987) The region of the IncN plasmid R46 coding for resistance to β-lactam antibiotics, streptomycin/spectinomycin and sulphonamides is closely related to antibiotic resistance segments found in IncW plasmids and in Tn21-like transposons. Nucleic Acids Res 15:7491–7501 (10.1093/nar/15.18.7491) / Nucleic Acids Res by RM Hall (1987)
  15. Hirsch PR, Beringer JE (1984) A physical map of pPH1J1 and pJB4J1. Plasmid 12:139–141 (10.1016/0147-619X(84)90059-3) / Plasmid by PR Hirsch (1984)
  16. Hirsch PR, Wang CL, Woodward MJ (1986) Construction of a Tn5 derivative determining resistance to gentamicin and spectinomycin using a fragment cloned from R1033. Gene 48:203–209 (10.1016/0378-1119(86)90078-8) / Gene by PR Hirsch (1986)
  17. Hollingshead S, Vapnek D (1985) Nucleotide sequence analysis of a gene encoding a streptomycin/spectinomycin adenyltransferase. Plasmid 13:17–30 (10.1016/0147-619X(85)90052-6) / Plasmid by S Hollingshead (1985)
  18. Hsiang MW, White TJ, Davies JE (1978) NH2-terminal sequence of the aminoglycoside acetyltransferase (3)-I mediated by plasmid RIP135. FEBS Lett 92:97–99 (10.1016/0014-5793(78)80730-3) / FEBS Lett by MW Hsiang (1978)
  19. Huovinen P, Huovinen S, Jacoby GA (1988) Sequence of PSE-2 β-lactamase. Antimicrob Agents Chemother 32:134–136 (10.1128/AAC.32.1.134) / Antimicrob Agents Chemother by P Huovinen (1988)
  20. Kagan SA (1981) Aminoglycoside acetyltransferase-3-I; structure and function. Ph.D. Thesis, University of Wisconsin
  21. Kagan SA, Davies JE (1980) Enzymatic modification of aminoglycoside antibiotics: mutations affecting the expression of aminoglycoside acetyltransferase-3. Plasmid 3:312–318 (10.1016/0147-619X(80)90043-8) / Plasmid by SA Kagan (1980)
  22. Lafond M, Couture F, Vezina G, Levesque RC (1989) DNA homology, structural features and evolutionary perspectives of multiresistance complex β-lactamase transposons. (In press) (10.1128/jb.171.12.6423-6429.1989)
  23. LeGoffic F, Moreau N (1973) Purification by affinity chromatography of an enzyme involved in gentamicin inactivation. FEBS Lett 29:289–291 (10.1016/0014-5793(73)80041-9) / FEBS Lett by F LeGoffic (1973)
  24. LeGoffic F, Martel A, Witchitz J (1974) 3-N-enzymatic acetylation of gentamicin, tobramycin and kanamycin byEscherichia coli carrying an R-factor. Antimicrob Agents Chemother 6:680–684 (10.1128/AAC.6.6.680) / Antimicrob Agents Chemother by F LeGoffic (1974)
  25. Maniatis T, Fritsch EF, Sambrook J (1982) Molecular Cloning. Cold Spring Harbor Laboratory
  26. Marti KM (1987) Kinetic characterisation of aminoglycoside acetyltransferase 3-1. Ph.D. Thesis, University of Wisconsin
  27. Martinez E, de la Cruz F (1988) Transposon Tn21 encodes arecA-independent site-specific integration system. Mol Gen Genet 211:320–325 (10.1007/BF00330610) / Mol Gen Genet by E Martinez (1988)
  28. Mitsuhashi S (1982) Antibacterial activity of aminoglycoside antibiotics. In: Umezawa H, Hooper IR (eds) Aminoglycoside Antibiotics. Springer-Verlag, Berlin, pp 205–220 (10.1007/978-3-642-68579-8_4) / Aminoglycoside Antibiotics by S Mitsuhashi (1982)
  29. Ouellette M, Roy PH (1986) Analysis by DNA probes of the OXA-1 β-lactamase gene and its transposon. Antimicrob Agents Chemother 30:46–51 (10.1128/AAC.30.1.46) / Antimicrob Agents Chemother by M Ouellette (1986)
  30. Ouellette M, Roy PH (1987) Homology of ORFs from Tn2603 and from R46 to site-specific recombinases. Nucleic Acids Res 15:10055–10056 (10.1093/nar/15.23.10055) / Nucleic Acids Res by M Ouellette (1987)
  31. Ouellette M, Bissonnette L, Roy PH (1987) Precise insertion of antibiotic resistance determinants into Tn21-like transposons: Nucleotide sequence of the OXA-1 β-lactamase gene. Proc Natl Acad Sci USA 84:7378–7382 (10.1073/pnas.84.21.7378) / Proc Natl Acad Sci USA by M Ouellette (1987)
  32. Piepersberg W, Distler J, Heinzel P, Perez-Gonzalez J-A (1988) Antibiotic resistance by modification: many resistance genes could be derived from cellular control genes in Actinomycetes — a hypothesis. Actinomycetologica, in press (10.3209/saj.2_83)
  33. Pratt JM (1984) Coupled transcription-translation in prokaryotic cell-free systems. In: Hames BD, Higgins SJ(eds) Transcription and translation: A practical approach. IRL Press, Oxford, pp 179–209 / Transcription and translation: A practical approach by JM Pratt (1984)
  34. Rubens CE, McNeill WF, Farrer WE (1979) A transposable plasmid DNA sequence inPseudomonas aeruginosa which mediates resistance to gentamicin and four other antibiotics. J Bacteriol 139:877–882 (10.1128/JB.139.3.877-882.1979) / J Bacteriol by CE Rubens (1979)
  35. Rubin RA (1987) Genetic analysis of the gentamicin resistance region of pPH1J1 and incorporation into a wide host range cloning vehicle. Plasmid 18:84–88 (10.1016/0147-619X(87)90081-3) / Plasmid by RA Rubin (1987)
  36. Schmidt F (1984) The role of insertions, deletions, and substitutions in the evolution of R6 related plasmids encoding aminoglycoside transferase ANT-(2″). Mol Gen Genet 194:248–259 (10.1007/BF00383524) / Mol Gen Genet by F Schmidt (1984)
  37. Schmidt F, Klopfer-Kaul I (1984) Evolutionary relationship between Tn21-like elements and pBP201, a plasmid fromKlebsiella pneumoniae mediating resistance to gentamicin and eight other drugs. Mol Gen Genet 197:109–119 (10.1007/BF00327930) / Mol Gen Genet by F Schmidt (1984)
  38. Simonsen CC, Chen EY, Levinson AD (1983) Identification of the type I trimethoprim-resistant dihydrofolate reductase specified by theEscherichia coli R-plasmid R483: comparison with procaryotic and eucaryotic dihydrofolate reductases. J Bacteriol 155:1001–1008 (10.1128/JB.155.3.1001-1008.1983) / J Bacteriol by CC Simonsen (1983)
  39. Smith DI, Gomez Lus R, Rubio Calvo M, Datta N, Jacob AE, Hedges RW (1975) Third type of plasmid conferring gentamicin resistance inPseudomonas aeruginosa. Antimicrob Agents Chemother 8:227–230 (10.1128/AAC.8.3.227) / Antimicrob Agents Chemother by DI Smith (1975)
  40. Sundström L, Rådström P, Swedberg G, Sköld O (1988) Site-specific recombination promotes linkage between trimethoprimand sulfonamide resistance genes. Sequence characterization ofdhfrV andsulI and a recombination active locus of Tn21. Mol Gen Genet 213:191–201 (10.1007/BF00339581) / Mol Gen Genet by L Sundström (1988)
  41. Swift G, McCarthy BJ, Heffron F (1981) DNA sequence of a plasmid-encoded dihydrofolate reductase. Mol Gen Genet 181:441–447 (10.1007/BF00428733) / Mol Gen Genet by G Swift (1981)
  42. Tait RC, Rempel H, Rodriguez RL, Kado CI (1985) The aminoglycoside resistance operon of the plasmid pSa: Nucleotide sequence of the streptomycin/spectinomycin resistance gene. Gene 36:97–104 (10.1016/0378-1119(85)90073-3) / Gene by RC Tait (1985)
  43. Tanaka M, Matshushita K, Yamamoto T (1985) Genesis of a complex transposon encoding the OXA-1 (type II) β-lactamase gene. Antimicrob Agents Chemother 28:227–234 (10.1128/AAC.28.2.227) / Antimicrob Agents Chemother by M Tanaka (1985)
  44. Tenover FC, Filpula D, Phillips KL, Plorde JJ (1988) Cloning and sequencing of a gene encoding an aminoglycoside 6′-N-acetyltransferase from an R factor ofCitrobacter diversus. J Bacteriol 170:471–473 (10.1128/jb.170.1.471-473.1988) / J Bacteriol by FC Tenover (1988)
  45. Umezawa H, Yagisawa M, Matsuhashi Y, Nagenawa H, Yamamoto H, Kondo S, Takenchi T, Chabbert YA (1973) Gentamicin acetyltransferase inEscherichia coli carrying R factor. J Antibiot 26:612–614 (10.7164/antibiotics.26.612) / J Antibiot by H Umezawa (1973)
  46. Wiedemann B, Meyer JF, Zuhlsdorf M (1987) Insertions of resistance genes into Tn21-like transposons. J Antimicrob Chemother 18:85–92 (10.1093/jac/18.Supplement_C.85) / J Antimicrob Chemother by B Wiedemann (1987)
  47. Williams JW, Northrop DB (1976) Purification and properties of gentamicin acetyltransferase I. Biochemistry 15:125–131 (10.1021/bi00646a019) / Biochemistry by JW Williams (1976)
  48. Williams JW, Northrop DB (1978a) Kinetic mechanisms of gentamicin acetyltransferase I. Biol Chem 253:5902–5907 (10.1016/S0021-9258(17)34553-2) / Biol Chem by JW Williams (1978)
  49. Williams JW, Northrop DB (1978b) Substrate specificity and structure-activity relationships of gentamicin acetyltransferase I. J Biol Chem 253:5908–5914 (10.1016/S0021-9258(17)34554-4) / J Biol Chem by JW Williams (1978)
  50. Witchitz JL (1972) Plasmid-mediated gentamicin resistance not associated with kanamycin resistance in Enterobacteriaceae. J Antibiot 25:622–624 (10.7164/antibiotics.25.622) / J Antibiot by JL Witchitz (1972)
Dates
Type When
Created 19 years ago (Aug. 10, 2006, 8:36 a.m.)
Deposited 4 years ago (July 31, 2021, 5:51 a.m.)
Indexed 40 minutes ago (Aug. 29, 2025, 5:39 a.m.)
Issued 36 years, 2 months ago (June 1, 1989)
Published 36 years, 2 months ago (June 1, 1989)
Published Print 36 years, 2 months ago (June 1, 1989)
Funders 0

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@article{Wohlleben_1989, title={On the evolution of Tn21-like multiresistance transposons: Sequence analysis of the gene (aacC1) for gentamicin acetyltransferase-3-I(AAC(3)-I), another member of the Tn21-based expression cassette}, volume={217}, ISSN={1432-1874}, url={http://dx.doi.org/10.1007/bf02464882}, DOI={10.1007/bf02464882}, number={2–3}, journal={Molecular and General Genetics MGG}, publisher={Springer Science and Business Media LLC}, author={Wohlleben, Wolfgang and Arnold, Walter and Bissonnette, Luc and Pelletier, Alex and Tanguay, Annie and Roy, Paul H. and Gamboa, Gary C. and Barry, Gerard F. and Aubert, Elisabeth and Davies, Julian and Kagan, Sarah A.}, year={1989}, month=jun, pages={202–208} }