DOI: 10.1007/bf02245056. Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys

Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys

10.1007/bf02245056

Crossref journal-article

Springer Science and Business Media LLC

Psychopharmacology (297)

Bibliography

Arnsten, A. F. T., Cai, J. X., Murphy, B. L., & Goldman-Rakic, P. S. (1994). Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys. Psychopharmacology, 116(2), 143â151.

Authors 4

A. F. T. Arnsten (first)
J. X. Cai (additional)
B. L. Murphy (additional)
P. S. Goldman-Rakic (additional)

References 33 Referenced 445

Adolfsson R, Gottfries C-G, Roos B-E, Winblad B (1979) Post-mortem distribution of dopamine and homovanillic acid in human brain, variations related to age, and a review of the literature. J Neural Transm 45:81–105 (10.1007/BF01250085) / J Neural Transm by R Adolfsson (1979)
Arnsten AFT, Cai JX (1993) Post-synaptic alpha-2 receptor stimulation improves memory in aged monkeys: Indirect effects of yohimbine vs. direct effects of clonidine. Neurobiol Aging 14:597–603 (10.1016/0197-4580(93)90044-C) / Neurobiol Aging by AFT Arnsten (1993)
Arnsten AFT, Goldman-Rakic PS (1985) Alpha-2 adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates. Science 230:1273–1276 (10.1126/science.2999977) / Science by AFT Arnsten (1985)
Arnsten AFT, Cai JX, Goldman-Rakic PS (1988) The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects. J Neurosci 8:4287–4298 (10.1523/JNEUROSCI.08-11-04287.1988) / J Neurosci by AFT Arnsten (1988)
Bartus RT (1979) Effects of aging on visual memory, sensory processing and discrimination learning in a nonhuman primate. In: Ordy JM, Brizzee K. (eds), Sensory systems and communication in the elderly (Aging vol 10). Raven Press, New York, pp 85–114 / Sensory systems and communication in the elderly (Aging vol 10) by RT Bartus (1979)
Bartus RT, Fleming D, Johnson HR (1978) Aging in the rhesus monkey: debilitating effects on short-term memory. J Gerontol 33:858–871 (10.1093/geronj/33.6.858) / J Gerontol by RT Bartus (1978)
Bartus RT, Dean RL, Fleming DL (1979) Aging in the rhesus monkey: effects on visual discrimination learning and reversal learning. J Gerontol 34:209–219 (10.1093/geronj/34.2.209) / J Gerontol by RT Bartus (1979)
Brozoski T, Brown RM, Rosvold HE, Goldman PS (1979) Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science 205:929–931 (10.1126/science.112679) / Science by T Brozoski (1979)
Brewster WK, Nichols DE, Riggs RM, Mottola DM, Lovenberg TW, Lewis MH, Mailman RB (1990) Trans-10,11-dihydroxy-5, 6, 6a, 7, 8, 12b-hexahydrobenzo [a] phenanthridine: a highly potent selective dopamine D1 full agonist. J Med Chem 33:1756–1764 (10.1021/jm00168a034) / J Med Chem by WK Brewster (1990)
Briggs CA, Pollock NJ, Frail DE, Paxson CL, Rakowski RF, Kang CH, Kebabian, JW (1991) Activation of the 5HT1c receptor expressed inXenopus oocytes by the benzazepines SCH23390 and SKF38393. Br J Pharmacol 104:1038–1044 (10.1111/j.1476-5381.1991.tb12546.x) / Br J Pharmacol by CA Briggs (1991)
Davis RE, Callahan MJ, Downs DA (1988) Clonidine disrupts aged-monkey delayed response performance. Drug Dev Res 12:279–286 (10.1002/ddr.430120311) / Drug Dev Res by RE Davis (1988)
de Keyser J, De Backer J-P, Vauquelin G, Ebinger, G (1990) The effect of aging on the D1 dopamine receptors in human frontal cortex. Brain Res 528:308–310 (10.1016/0006-8993(90)91672-4) / Brain Res by J Keyser de (1990)
Elsworth JD, Lawrence MS, Roth RH, Taylor JR, Mailman RB, Nichols DE, Lewis MH, Redmond DE Jr (1991) D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the Vervet monkey. J Pharmacol Exp Ther 259:595–600 / J Pharmacol Exp Ther by JD Elsworth (1991)
Goldman PS, Rosvold HE (1970) Localization of function within the dorsolateral prefrontal cortex of the rhesus monkey. Exp Neurol 27:291–304 (10.1016/0014-4886(70)90222-0) / Exp Neurol by PS Goldman (1970)
Goldman-Rakic PS, Brown RM (1981) Regional changes of monoamines in cerebral cortex and subcortical structures of aging rhesus monkeys. Neuroscience 6:177–187 (10.1016/0306-4522(81)90053-1) / Neuroscience by PS Goldman-Rakic (1981)
Gotham AM, Brown RG, Marsden CD (1988) “Frontal” cognative function in patients with Parkinson's disease “on” and “off” levodopa. Brain 111:299–321 (10.1093/brain/111.2.299) / Brain by AM Gotham (1988)
Hess EJ, Bracha HS, Kleinman JE, Creese I (1987) Dopamine receptor subtype imbalance in schizophrenia. Life Sci 40:1487–1497 (10.1016/0024-3205(87)90381-X) / Life Sci by EJ Hess (1987)
Lapin BA, Krilova RI, Cherkovich GM, Asanov NS (1979) Observations from Sukhumi. In: Bowden DM (ed) Aging in nonhuman primates. Van Nostrand Reinhold, New York, pp 14–37 / Aging in nonhuman primates by BA Lapin (1979)
Lovenberg TW, Brewster WK, Mottola DM, Lee RC, Riggs RM, Nichols DE, Lewis MH, Mailman RB (1989) Dihydrexidine, a novel selective high potency full D-1 receptor agonist. Eur J Pharmacol 166:111–113 (10.1016/0014-2999(89)90690-0) / Eur J Pharmacol by TW Lovenberg (1989)
Mottola DM, Cook LL, Jones SR, Booth RG, Nichols DE, Mailman RB (1991) Dihydrexidine, a selective dopamine receptor agonist that may discriminate postsynaptic D2 receptors. Soc Neurosci Abstr 17:818 / Soc Neurosci Abstr by DM Mottola (1991)
Mottola DM, Brewster WK, Cook LL, Nichols DE, Mailman RB (1992) Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist. J Pharmacol Exp Ther 262:383–393 / J Pharmacol Exp Ther by DM Mottola (1992)
Nichols NF, Schreur PJKD, Smith MW, Hoffmann WE, Nichols DE, Piercey MF (1992) Activation of postsynaptic but not presynaptic dopamine receptors by dihydrexidine, a potent D1 and D2 receptor ligand. Soc Neurosci Abstr 18:1170 / Soc Neurosci Abstr by NF Nichols (1992)
Pifl C, Reither H, Hornykiewicz O (1991) Lower efficacy of the dopamine D1 agonist, SKF38393, to stimulate adenylyl cyclase activity in primate than in rodent striatum. Eur J Pharmacol 202:273–276 (10.1016/0014-2999(91)90304-9) / Eur J Pharmacol by C Pifl (1991)
Rapp PR, Amaral DG (1989) Evidence for task-dependent memory dysfunction in the aged monkey. J Neurosci 9:3568–3576 (10.1523/JNEUROSCI.09-10-03568.1989) / J Neurosci by PR Rapp (1989)
Sawaguchi T, Goldman-Rakic PS (1991) D1 dopamine receptors in prefrontal cortex: Involvement in working memory. Science 251:947–950 (10.1126/science.1825731) / Science by T Sawaguchi (1991)
Schneider JS (1992) Behavioral and neuropathologial consequences of chronic exposure to low doses of the dopaminergic neurotoxin MPTP. In: Isaacson RL, Jensen KF (eds) The vulnerable brain and environmental risks, vol 2. Toxins in food. Plenum Press, New York, pp 293–308 (10.1007/978-1-4615-3330-6_16) / The vulnerable brain and environmental risks, vol 2. Toxins in food by JS Schneider (1992)
Suhara T, Fukuda H, Inoue O, Itoh T, Suzuki K, Yamasaki T, Tateno Y (1991) Age-related changes in human D1 dopamine receptors measured by positron emission tomography. Psychopharmacology 103:41–45 (10.1007/BF02244071) / Psychopharmacology by T Suhara (1991)
Taylor JR, Lawrence MS, Redmond DE Jr, Elsworth JD, Roth RH, Nichols DE, Mailman RB (1991) Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys. Eur J Pharmacol 199:389–391 (10.1016/0014-2999(91)90508-N) / Eur J Pharmacol by JR Taylor (1991)
Tigges J, Gordon TP, McClure HM, Hall EC, Peters A (1988) Survival rate and lifespan of rhesus monkeys at the Yerkes Regional Primate Research Center. Am J Primatol 15:263–273 (10.1002/ajp.1350150308) / Am J Primatol by J Tigges (1988)
Walker LC, Kitt CA, Struble RG, Wagster MV, Price DL, Cork LC (1988) The neural basis of memory decline in aged monkeys. Neurobiol Aging 9:657–666 (10.1016/S0197-4580(88)80130-1) / Neurobiol Aging by LC Walker (1988)
Watts VJ, Lawler CP, Knoerzer T, Mayleben MA, Neve KA, Nichols DE, Mailman RB (1993) Hexahydrobenzo [a] phenanthridines: ligands with high affinity and selectivity for D3 dopamine receptors. Eur J Pharmacol 239:271–273 (10.1016/0014-2999(93)91012-C) / Eur J Pharmacol by VJ Watts (1993)
Watts VJ, Lawler CP, Gilmore JH, Southerland SB, Nichols DE, Mailman RB (1994) Efficacy at D1 dopamine receptors in primates and rodents: comparison of full (dihydrexidine) and partial (SKF38393) efficacy dopamine agonists. Eur J Pharmacol (in press)
Wenk GL, Pierce DJ, Struble RG, Price DL, Cork LC (1989) Age-related changes in multiple neurotransmitter systems in the monkey brain. Neurobiol Aging 10:11–19 (10.1016/S0197-4580(89)80005-3) / Neurobiol Aging by GL Wenk (1989)

Dates

Type	When
Created	19 years, 9 months ago (Nov. 15, 2005, 8:39 a.m.)
Deposited	6 years, 3 months ago (May 15, 2019, 1:33 p.m.)
Indexed	1 month, 3 weeks ago (July 3, 2025, 10:47 a.m.)
Issued	30 years, 10 months ago (Oct. 1, 1994)
Published	30 years, 10 months ago (Oct. 1, 1994)
Published Print	30 years, 10 months ago (Oct. 1, 1994)

Funders 0

None

BibTeX

@article{Arnsten_1994, title={Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys}, volume={116}, ISSN={1432-2072}, url={http://dx.doi.org/10.1007/bf02245056}, DOI={10.1007/bf02245056}, number={2}, journal={Psychopharmacology}, publisher={Springer Science and Business Media LLC}, author={Arnsten, A. F. T. and Cai, J. X. and Murphy, B. L. and Goldman-Rakic, P. S.}, year={1994}, month=oct, pages={143–151} }

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