Abstract
Guinea-pig kidney contains β-4-N-acetylgalactosaminyltransferase which may be involved in the biosynthesis of the Sd a determinant expressed on Tamm-Horsfall glycoprotein. In the present study we show that this enzyme is expressed far more in the medulla than in the cortex of the kidney and that, among the other organs tested, is expressed only in colon and caecum. This transferase is ontogenically regulated, in that its activity is low at birth and increases as a function of age. From several aspects, the tissue distribution and the ontogenic expression of β-4-N-acetylgalactosaminyl-transferase and Tamm-Horsfall glycoprotein are similar.
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Dates
Type | When |
---|---|
Created | 20 years, 6 months ago (Feb. 6, 2005, 7:52 a.m.) |
Deposited | 3 years, 9 months ago (Nov. 16, 2021, 1:57 p.m.) |
Indexed | 1 year, 1 month ago (July 20, 2024, 11:39 a.m.) |
Issued | 37 years, 9 months ago (Dec. 1, 1987) |
Published | 37 years, 9 months ago (Dec. 1, 1987) |
Published Print | 37 years, 9 months ago (Dec. 1, 1987) |
@article{Dall_Olio_1987, title={Tissue distribution and age-dependent expression of β-4-N-acetylgalactosaminyltransferase in guinea-pig}, volume={7}, ISSN={1573-4935}, url={http://dx.doi.org/10.1007/bf01122125}, DOI={10.1007/bf01122125}, number={12}, journal={Bioscience Reports}, publisher={Portland Press Ltd.}, author={Dall’Olio, F. and Malagolini, N. and Serafini-Cessi, F.}, year={1987}, month=dec, pages={925–932} }