DOI: 10.1007/bf00330673. Function of RNase H in DNA replication revealed by RNase H defective mutants of Escherichia coli

Function of RNase H in DNA replication revealed by RNase H defective mutants of Escherichia coli

10.1007/bf00330673

Crossref journal-article

Springer Science and Business Media LLC

Molecular and General Genetics MGG (297)

Bibliography

Ogawa, T., & Okazaki, T. (1984). Function of RNase H in DNA replication revealed by RNase H defective mutants of Escherichia coli. Molecular and General Genetics MGG, 193(2), 231â237.

Authors 2

Tohru Ogawa (first)
Tuneko Okazaki (additional)

References 40 Referenced 105

Aposhian HV, Kornberg A (1962) Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli. A new enzyme. J Biol Chem 237:519–525 (10.1016/S0021-9258(18)93954-2) / J Biol Chem by HV Aposhian (1962)
Arendes J, Carl PC, Sugino A (1982) A mutation in the rnh-locus of Escherichia coli affects the structural gene for RNase H. J Biol Chem 257:4719–4722 (10.1016/S0021-9258(18)34584-8) / J Biol Chem by J Arendes (1982)
Berkower I, Leis J, Hurwitz J (1973) Isolation and characterization of an endonuclease from Escherichia coli specific for ribonucleic acid in ribonucleic acid-deoxyribonucleic acid hybrid structures. J Biol Chem 248:5914–5921 (10.1016/S0021-9258(19)43488-1) / J Biol Chem by I Berkower (1973)
Carl PL, Bloom L, Crouch RJ (1980) Isolation and mapping of a mutation in Escherichia coli with altered levels of ribonuclease H. J Bacteriol 177:28–35 (10.1128/JB.144.1.28-35.1980) / J Bacteriol by PL Carl (1980)
Crouch RJ, Dirksen M-L (1982) Ribonuclease H. In: Linn SM, Robert RJ (eds) Nuclease. Cold Spring Harbor Laboratory, New York, pp 211–241 / Nuclease by RJ Crouch (1982)
Davis RW, Botstein D, Roth JR (1980) Advanced bacterial genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York / Advanced bacterial genetics by RW Davis (1980)
Hershfield V, Boyer HW, Chow L, Helinski DR (1976) Characterization of a mini-ColE1 plasmid. J Bacteriol 126:447–453 (10.1128/JB.126.1.447-453.1976) / J Bacteriol by V Hershfield (1976)
Hillenbrand G, Staudenbauer WL (1982) Discriminatory function of ribonuclease H in the selective initiation of plasmid DNA replication. Nucleic Acids Res 10:833–853 (10.1093/nar/10.3.833) / Nucleic Acids Res by G Hillenbrand (1982)
Hong J-S, Ames BN (1971) Localized mutagenesis of any specific small region of the bacterial chromosome. Proc Natl Acad Sci USA 68:3158–3162 (10.1073/pnas.68.12.3158) / Proc Natl Acad Sci USA by J-S Hong (1971)
Horiuchi T, Maki H, Maruyama M, Sekiguchi M (1981) Identification of the dnaQ gene product and location of the structural gene for RNase H of Escherichia coli by cloning of the genes. Proc Natl Acad Sci USA 78:3770–3774 (10.1073/pnas.78.6.3770) / Proc Natl Acad Sci USA by T Horiuchi (1981)
Itoh T, Tomizawa J (1980) Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H. Proc Natl Acad Sci USA 77:2450–2454 (10.1073/pnas.77.5.2450) / Proc Natl Acad Sci USA by T Itoh (1980)
Itoh T, Tomizawa J (1982) Purification of ribonuclease H as a factor required for initiation of in vitro ColE1 DNA replication. Nucleic Acids Res 10:5949–5965 (10.1093/nar/10.19.5949) / Nucleic Acids Res by T Itoh (1982)
Kanaya S, Crouch RJ (1983) DNA sequence of the gene coding for Escherichia coli ribonuclease H. J Biol Chem 258:1276–1281 (10.1016/S0021-9258(18)33189-2) / J Biol Chem by S Kanaya (1983)
Keller W, Crouch R (1972) Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin. Proc Natl Acad Sci USA 69:3360–3364 (10.1073/pnas.69.11.3360) / Proc Natl Acad Sci USA by W Keller (1972)
Kogoma T (1978) A novel Escherichia coli mutant capable of DNA replication in the absence of protein synthesis. J Mol Biol 121:55–69 (10.1016/0022-2836(78)90262-0) / J Mol Biol by T Kogoma (1978)
Kogoma T, Lark KG (1970) DNA replication in Escherichia coli: Replication in absence of protein synthesis after replication inhibition. J Mol Biol 52:143–164 (10.1016/0022-2836(70)90022-7) / J Mol Biol by T Kogoma (1970)
Kogoma T, von Meyenburg K (1983) The origin of replication, oriC and the dnaA protein are dispensable in the stable DNA replication (sdrA) mutants of Escherichia coli K-12. EMBO J 2:463–468 (10.1002/j.1460-2075.1983.tb01445.x) / EMBO J by T Kogoma (1983)
Kornberg A (1979) DNA replication. Freeman, San Francisco, pp 137–139 / DNA replication by A Kornberg (1979)
Kurosawa Y, Ogawa T, Hirose S, Okazaki T, Okazaki R (1975) Mechanism of DNA chain growth. XV. RNA-linked nascent DNA pieces in Escherichia coli strains assayed with spleen exonuclease. J Mol Biol 96:653–664 (10.1016/0022-2836(75)90144-8) / J Mol Biol by Y Kurosawa (1975)
Kurosawa Y, Okazaki T (1979) Structure of the RNA portion of the RNA-linked DNA pieces in bacteriophage T4-infected Escherichia coli cells. J Mol Biol 135:841–861 (10.1016/0022-2836(79)90515-1) / J Mol Biol by Y Kurosawa (1979)
Maxam AA, Gilbert W (1980) Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol 65:499–560 (10.1016/S0076-6879(80)65059-9) / Methods Enzymol by AA Maxam (1980)
Maxwell IH, Maxwell F, Hahn WE (1977) Removal of RNase activity from DNase by affinity chromatography on agarosecoupled aminophenylphosphoryl-uridine-2′(3′)-phosphate. Nucleic Acids Res 4:241–246 (10.1093/nar/4.1.241) / Nucleic Acids Res by IH Maxwell (1977)
Naito S, Uchida H (1980) Initiation of DNA replication in a ColE1-type plasmid: Isolation of mutations in the ori region. Proc Natl Acad Sci USA 77:6744–6748 (10.1073/pnas.77.11.6744) / Proc Natl Acad Sci USA by S Naito (1980)
Ogawa T, Hirose S, Okazaki T, Okazaki R (1977) Mechanism of DNA chain growth XVI. Analyses of RNA-linked DNA pieces in Escherichia coli with polynucleotide kinase. J Mol Biol 112:121–140 (10.1016/S0022-2836(77)80160-5) / J Mol Biol by T Ogawa (1977)
Ogawa T, Okazaki T (1979) RNA-linked nascent DNA pieces in phage T7-infected Escherichia coli. III. Detection of intact primer RNA. Nucl Acids Res 7:1621–1633 (10.1093/nar/7.6.1621) / Nucl Acids Res by T Ogawa (1979)
Ogawa T, Okazaki T (1980) Discontinuous DNA replication. Annu Rev Biochem 49:421–457 (10.1146/annurev.bi.49.070180.002225) / Annu Rev Biochem by T Ogawa (1980)
Oka A, Nomura N, Sugimoto K, Sugisaki H, Takanami M (1978) Nucleotide sequence at the insertion sites of a kanamycin transposon. Nature 276:845–847 (10.1038/276845a0) / Nature by A Oka (1978)
Okazaki R, Okazaki T, Sakabe K, Sugimoto K, Sugino A (1968) Mechanism of DNA chain growth I. Possible discontinuity and unusual secondary structure of newly synthesized chains. Proc Natl Acad Sci USA 59:598–605 (10.1073/pnas.59.2.598) / Proc Natl Acad Sci USA by R Okazaki (1968)
Okazaki T, Kurosawa Y, Ogawa T, Seki T, Shinozaki K, Hirose T (1979) Cold Spring Harbor Symp Quant Biol 43:203–219 (10.1101/SQB.1979.043.01.026) / Cold Spring Harbor Symp Quant Biol by T Okazaki (1979)
Richardson CC (1966) Exonuclease III from Escherichia coli. In: Cantoni GL, Davies DR (eds) Procedures in nucleic acid research. Harper and Row Publishers, New York, pp 212–223 / Procedures in nucleic acid research by CC Richardson (1966)
Seki T, Okazaki T (1979) RNA-linked nascent DNA pieces in phage T7-infected Escherichia coli II. Priming structure of the RNA chain. Nucleic Acids Res 7:1603–1619 (10.1093/nar/7.6.1603) / Nucleic Acids Res by T Seki (1979)
Shinozaki K, Okazaki T (1978) T7 gene 6 exonuclease has an RNase H activity. Nucleic Acids Res 5:4245–4261 (10.1093/nar/5.11.4245) / Nucleic Acids Res by K Shinozaki (1978)
Tomizawa J, Itoh T (1981) Plasmid ColE1 incompatibility determined by interaction of RNA I with primer transcript. Proc Natl Acad Sci USA 78:6096–6100 (10.1073/pnas.78.10.6096) / Proc Natl Acad Sci USA by J Tomizawa (1981)
Tomizawa J, Itoh T, Selzer G, Som T (1981) Inhibition of ColE1 RNA primer formation by a plasmic-specified small DNA. Proc Natl Acad Sci USA 78:1421–1425 (10.1073/pnas.78.3.1421) / Proc Natl Acad Sci USA by J Tomizawa (1981)
Uyemura D, Eichler DC, Lehman IR (1976) Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. II. The polAex1 mutation. J Biol Chem 251:4085–4089 (10.1016/S0021-9258(17)33358-6) / J Biol Chem by D Uyemura (1976)
Venkatesan S, Gershowitz A, Moss B (1980) Modification of the 5′ end of mRNA. J Biol Chem 255:903–908 (10.1016/S0021-9258(19)86118-5) / J Biol Chem by S Venkatesan (1980)
Walseth TF, Johnson RA (1979) The enzymatic preparation of [α-32P]nucleoside triphosphates, cyclic [32P]AMP, and cyclic [32P]GMP. Biochim Biophys Acta 562:11–31 (10.1016/0005-2787(79)90122-9) / Biochim Biophys Acta by TF Walseth (1979)
Weiss B, Rogers SG, Taylor AF (1978) The endonuclease activity of exonuclease III and the repair of uracil-containing DNA in Escherichia coli. In: Hanawalt PC, Friedberg EC, Fox CF (eds) DNA repair mechanism. Academic Press, New York, pp 191–194 (10.1016/B978-0-12-322650-1.50036-9) / DNA repair mechanism by B Weiss (1978)
Womble DD, Taylor DP, Rownd RH (1977) Method for obtaining more-accurate covalently closed circular plasmid-to-chromosome ratios from bacterial lysates by dye-buoyant density centrifugation. J Bacteriol 130:148–153 (10.1128/JB.130.1.148-153.1977) / J Bacteriol by DD Womble (1977)
Yamaguchi K, Tomizawa J (1980) Establishement of Escherichia coli cells with an integrated high copy number plasmid. Mol Gen Genet 178:525–533 (10.1007/BF00337857) / Mol Gen Genet by K Yamaguchi (1980)

Dates

Type	When
Created	20 years, 10 months ago (Oct. 23, 2004, 9:26 p.m.)
Deposited	4 years, 2 months ago (June 26, 2021, 5:33 p.m.)
Indexed	2 months, 4 weeks ago (June 4, 2025, 10:27 a.m.)
Issued	41 years, 7 months ago (Feb. 1, 1984)
Published	41 years, 7 months ago (Feb. 1, 1984)
Published Print	41 years, 7 months ago (Feb. 1, 1984)

Funders 0

None

BibTeX

@article{Ogawa_1984, title={Function of RNase H in DNA replication revealed by RNase H defective mutants of Escherichia coli}, volume={193}, ISSN={1432-1874}, url={http://dx.doi.org/10.1007/bf00330673}, DOI={10.1007/bf00330673}, number={2}, journal={Molecular and General Genetics MGG}, publisher={Springer Science and Business Media LLC}, author={Ogawa, Tohru and Okazaki, Tuneko}, year={1984}, month=feb, pages={231–237} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        6,
        4
      ]
    ],
    "date-time": "2025-06-04T14:27:52Z",
    "timestamp": 1749047272386
  },
  "reference-count": 40,
  "publisher": "Springer Science and Business Media LLC",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1984,
            2,
            1
          ]
        ],
        "date-time": "1984-02-01T00:00:00Z",
        "timestamp": 444441600000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "http://www.springer.com/tdm"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1984,
        2
      ]
    ]
  },
  "DOI": "10.1007/bf00330673",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2004,
        10,
        24
      ]
    ],
    "date-time": "2004-10-24T01:26:49Z",
    "timestamp": 1098581209000
  },
  "page": "231-237",
  "source": "Crossref",
  "is-referenced-by-count": 105,
  "title": "Function of RNase H in DNA replication revealed by RNase H defective mutants of Escherichia coli",
  "prefix": "10.1007",
  "volume": "193",
  "author": [
    {
      "given": "Tohru",
      "family": "Ogawa",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Tuneko",
      "family": "Okazaki",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "297",
  "reference": [
    {
      "key": "BF00330673_CR1",
      "doi-asserted-by": "crossref",
      "first-page": "519",
      "DOI": "10.1016/S0021-9258(18)93954-2",
      "volume": "237",
      "author": "HV Aposhian",
      "year": "1962",
      "unstructured": "Aposhian HV, Kornberg A (1962) Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli. A new enzyme. J Biol Chem 237:519\u2013525",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "BF00330673_CR2",
      "doi-asserted-by": "crossref",
      "first-page": "4719",
      "DOI": "10.1016/S0021-9258(18)34584-8",
      "volume": "257",
      "author": "J Arendes",
      "year": "1982",
      "unstructured": "Arendes J, Carl PC, Sugino A (1982) A mutation in the rnh-locus of Escherichia coli affects the structural gene for RNase H. J Biol Chem 257:4719\u20134722",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "BF00330673_CR3",
      "doi-asserted-by": "crossref",
      "first-page": "5914",
      "DOI": "10.1016/S0021-9258(19)43488-1",
      "volume": "248",
      "author": "I Berkower",
      "year": "1973",
      "unstructured": "Berkower I, Leis J, Hurwitz J (1973) Isolation and characterization of an endonuclease from Escherichia coli specific for ribonucleic acid in ribonucleic acid-deoxyribonucleic acid hybrid structures. J Biol Chem 248:5914\u20135921",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "BF00330673_CR4",
      "doi-asserted-by": "crossref",
      "first-page": "28",
      "DOI": "10.1128/JB.144.1.28-35.1980",
      "volume": "177",
      "author": "PL Carl",
      "year": "1980",
      "unstructured": "Carl PL, Bloom L, Crouch RJ (1980) Isolation and mapping of a mutation in Escherichia coli with altered levels of ribonuclease H. J Bacteriol 177:28\u201335",
      "journal-title": "J Bacteriol"
    },
    {
      "key": "BF00330673_CR5",
      "first-page": "211",
      "volume-title": "Nuclease",
      "author": "RJ Crouch",
      "year": "1982",
      "unstructured": "Crouch RJ, Dirksen M-L (1982) Ribonuclease H. In: Linn SM, Robert RJ (eds) Nuclease. Cold Spring Harbor Laboratory, New York, pp 211\u2013241"
    },
    {
      "key": "BF00330673_CR6",
      "volume-title": "Advanced bacterial genetics",
      "author": "RW Davis",
      "year": "1980",
      "unstructured": "Davis RW, Botstein D, Roth JR (1980) Advanced bacterial genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York"
    },
    {
      "key": "BF00330673_CR7",
      "doi-asserted-by": "crossref",
      "first-page": "447",
      "DOI": "10.1128/JB.126.1.447-453.1976",
      "volume": "126",
      "author": "V Hershfield",
      "year": "1976",
      "unstructured": "Hershfield V, Boyer HW, Chow L, Helinski DR (1976) Characterization of a mini-ColE1 plasmid. J Bacteriol 126:447\u2013453",
      "journal-title": "J Bacteriol"
    },
    {
      "key": "BF00330673_CR8",
      "doi-asserted-by": "crossref",
      "first-page": "833",
      "DOI": "10.1093/nar/10.3.833",
      "volume": "10",
      "author": "G Hillenbrand",
      "year": "1982",
      "unstructured": "Hillenbrand G, Staudenbauer WL (1982) Discriminatory function of ribonuclease H in the selective initiation of plasmid DNA replication. Nucleic Acids Res 10:833\u2013853",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "BF00330673_CR9",
      "doi-asserted-by": "crossref",
      "first-page": "3158",
      "DOI": "10.1073/pnas.68.12.3158",
      "volume": "68",
      "author": "J-S Hong",
      "year": "1971",
      "unstructured": "Hong J-S, Ames BN (1971) Localized mutagenesis of any specific small region of the bacterial chromosome. Proc Natl Acad Sci USA 68:3158\u20133162",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "BF00330673_CR10",
      "doi-asserted-by": "crossref",
      "first-page": "3770",
      "DOI": "10.1073/pnas.78.6.3770",
      "volume": "78",
      "author": "T Horiuchi",
      "year": "1981",
      "unstructured": "Horiuchi T, Maki H, Maruyama M, Sekiguchi M (1981) Identification of the dnaQ gene product and location of the structural gene for RNase H of Escherichia coli by cloning of the genes. Proc Natl Acad Sci USA 78:3770\u20133774",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "BF00330673_CR11",
      "doi-asserted-by": "crossref",
      "first-page": "2450",
      "DOI": "10.1073/pnas.77.5.2450",
      "volume": "77",
      "author": "T Itoh",
      "year": "1980",
      "unstructured": "Itoh T, Tomizawa J (1980) Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H. Proc Natl Acad Sci USA 77:2450\u20132454",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "BF00330673_CR12",
      "doi-asserted-by": "crossref",
      "first-page": "5949",
      "DOI": "10.1093/nar/10.19.5949",
      "volume": "10",
      "author": "T Itoh",
      "year": "1982",
      "unstructured": "Itoh T, Tomizawa J (1982) Purification of ribonuclease H as a factor required for initiation of in vitro ColE1 DNA replication. Nucleic Acids Res 10:5949\u20135965",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "BF00330673_CR13",
      "doi-asserted-by": "crossref",
      "first-page": "1276",
      "DOI": "10.1016/S0021-9258(18)33189-2",
      "volume": "258",
      "author": "S Kanaya",
      "year": "1983",
      "unstructured": "Kanaya S, Crouch RJ (1983) DNA sequence of the gene coding for Escherichia coli ribonuclease H. J Biol Chem 258:1276\u20131281",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "BF00330673_CR14",
      "doi-asserted-by": "crossref",
      "first-page": "3360",
      "DOI": "10.1073/pnas.69.11.3360",
      "volume": "69",
      "author": "W Keller",
      "year": "1972",
      "unstructured": "Keller W, Crouch R (1972) Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin. Proc Natl Acad Sci USA 69:3360\u20133364",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "BF00330673_CR15",
      "doi-asserted-by": "crossref",
      "first-page": "55",
      "DOI": "10.1016/0022-2836(78)90262-0",
      "volume": "121",
      "author": "T Kogoma",
      "year": "1978",
      "unstructured": "Kogoma T (1978) A novel Escherichia coli mutant capable of DNA replication in the absence of protein synthesis. J Mol Biol 121:55\u201369",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "BF00330673_CR16",
      "doi-asserted-by": "crossref",
      "first-page": "143",
      "DOI": "10.1016/0022-2836(70)90022-7",
      "volume": "52",
      "author": "T Kogoma",
      "year": "1970",
      "unstructured": "Kogoma T, Lark KG (1970) DNA replication in Escherichia coli: Replication in absence of protein synthesis after replication inhibition. J Mol Biol 52:143\u2013164",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "BF00330673_CR17",
      "doi-asserted-by": "crossref",
      "first-page": "463",
      "DOI": "10.1002/j.1460-2075.1983.tb01445.x",
      "volume": "2",
      "author": "T Kogoma",
      "year": "1983",
      "unstructured": "Kogoma T, von Meyenburg K (1983) The origin of replication, oriC and the dnaA protein are dispensable in the stable DNA replication (sdrA) mutants of Escherichia coli K-12. EMBO J 2:463\u2013468",
      "journal-title": "EMBO J"
    },
    {
      "key": "BF00330673_CR18",
      "first-page": "137",
      "volume-title": "DNA replication",
      "author": "A Kornberg",
      "year": "1979",
      "unstructured": "Kornberg A (1979) DNA replication. Freeman, San Francisco, pp 137\u2013139"
    },
    {
      "key": "BF00330673_CR19",
      "doi-asserted-by": "crossref",
      "first-page": "653",
      "DOI": "10.1016/0022-2836(75)90144-8",
      "volume": "96",
      "author": "Y Kurosawa",
      "year": "1975",
      "unstructured": "Kurosawa Y, Ogawa T, Hirose S, Okazaki T, Okazaki R (1975) Mechanism of DNA chain growth. XV. RNA-linked nascent DNA pieces in Escherichia coli strains assayed with spleen exonuclease. J Mol Biol 96:653\u2013664",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "BF00330673_CR20",
      "doi-asserted-by": "crossref",
      "first-page": "841",
      "DOI": "10.1016/0022-2836(79)90515-1",
      "volume": "135",
      "author": "Y Kurosawa",
      "year": "1979",
      "unstructured": "Kurosawa Y, Okazaki T (1979) Structure of the RNA portion of the RNA-linked DNA pieces in bacteriophage T4-infected Escherichia coli cells. J Mol Biol 135:841\u2013861",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "BF00330673_CR21",
      "doi-asserted-by": "crossref",
      "first-page": "499",
      "DOI": "10.1016/S0076-6879(80)65059-9",
      "volume": "65",
      "author": "AA Maxam",
      "year": "1980",
      "unstructured": "Maxam AA, Gilbert W (1980) Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol 65:499\u2013560",
      "journal-title": "Methods Enzymol"
    },
    {
      "key": "BF00330673_CR22",
      "doi-asserted-by": "crossref",
      "first-page": "241",
      "DOI": "10.1093/nar/4.1.241",
      "volume": "4",
      "author": "IH Maxwell",
      "year": "1977",
      "unstructured": "Maxwell IH, Maxwell F, Hahn WE (1977) Removal of RNase activity from DNase by affinity chromatography on agarosecoupled aminophenylphosphoryl-uridine-2\u2032(3\u2032)-phosphate. Nucleic Acids Res 4:241\u2013246",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "BF00330673_CR23",
      "doi-asserted-by": "crossref",
      "first-page": "6744",
      "DOI": "10.1073/pnas.77.11.6744",
      "volume": "77",
      "author": "S Naito",
      "year": "1980",
      "unstructured": "Naito S, Uchida H (1980) Initiation of DNA replication in a ColE1-type plasmid: Isolation of mutations in the ori region. Proc Natl Acad Sci USA 77:6744\u20136748",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "BF00330673_CR24",
      "doi-asserted-by": "crossref",
      "first-page": "121",
      "DOI": "10.1016/S0022-2836(77)80160-5",
      "volume": "112",
      "author": "T Ogawa",
      "year": "1977",
      "unstructured": "Ogawa T, Hirose S, Okazaki T, Okazaki R (1977) Mechanism of DNA chain growth XVI. Analyses of RNA-linked DNA pieces in Escherichia coli with polynucleotide kinase. J Mol Biol 112:121\u2013140",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "BF00330673_CR25",
      "doi-asserted-by": "crossref",
      "first-page": "1621",
      "DOI": "10.1093/nar/7.6.1621",
      "volume": "7",
      "author": "T Ogawa",
      "year": "1979",
      "unstructured": "Ogawa T, Okazaki T (1979) RNA-linked nascent DNA pieces in phage T7-infected Escherichia coli. III. Detection of intact primer RNA. Nucl Acids Res 7:1621\u20131633",
      "journal-title": "Nucl Acids Res"
    },
    {
      "key": "BF00330673_CR26",
      "doi-asserted-by": "crossref",
      "first-page": "421",
      "DOI": "10.1146/annurev.bi.49.070180.002225",
      "volume": "49",
      "author": "T Ogawa",
      "year": "1980",
      "unstructured": "Ogawa T, Okazaki T (1980) Discontinuous DNA replication. Annu Rev Biochem 49:421\u2013457",
      "journal-title": "Annu Rev Biochem"
    },
    {
      "key": "BF00330673_CR27",
      "doi-asserted-by": "crossref",
      "first-page": "845",
      "DOI": "10.1038/276845a0",
      "volume": "276",
      "author": "A Oka",
      "year": "1978",
      "unstructured": "Oka A, Nomura N, Sugimoto K, Sugisaki H, Takanami M (1978) Nucleotide sequence at the insertion sites of a kanamycin transposon. Nature 276:845\u2013847",
      "journal-title": "Nature"
    },
    {
      "key": "BF00330673_CR28",
      "doi-asserted-by": "crossref",
      "first-page": "598",
      "DOI": "10.1073/pnas.59.2.598",
      "volume": "59",
      "author": "R Okazaki",
      "year": "1968",
      "unstructured": "Okazaki R, Okazaki T, Sakabe K, Sugimoto K, Sugino A (1968) Mechanism of DNA chain growth I. Possible discontinuity and unusual secondary structure of newly synthesized chains. Proc Natl Acad Sci USA 59:598\u2013605",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "BF00330673_CR29",
      "doi-asserted-by": "crossref",
      "first-page": "203",
      "DOI": "10.1101/SQB.1979.043.01.026",
      "volume": "43",
      "author": "T Okazaki",
      "year": "1979",
      "unstructured": "Okazaki T, Kurosawa Y, Ogawa T, Seki T, Shinozaki K, Hirose T (1979) Cold Spring Harbor Symp Quant Biol 43:203\u2013219",
      "journal-title": "Cold Spring Harbor Symp Quant Biol"
    },
    {
      "key": "BF00330673_CR30",
      "first-page": "212",
      "volume-title": "Procedures in nucleic acid research",
      "author": "CC Richardson",
      "year": "1966",
      "unstructured": "Richardson CC (1966) Exonuclease III from Escherichia coli. In: Cantoni GL, Davies DR (eds) Procedures in nucleic acid research. Harper and Row Publishers, New York, pp 212\u2013223"
    },
    {
      "key": "BF00330673_CR31",
      "doi-asserted-by": "crossref",
      "first-page": "1603",
      "DOI": "10.1093/nar/7.6.1603",
      "volume": "7",
      "author": "T Seki",
      "year": "1979",
      "unstructured": "Seki T, Okazaki T (1979) RNA-linked nascent DNA pieces in phage T7-infected Escherichia coli II. Priming structure of the RNA chain. Nucleic Acids Res 7:1603\u20131619",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "BF00330673_CR32",
      "doi-asserted-by": "crossref",
      "first-page": "4245",
      "DOI": "10.1093/nar/5.11.4245",
      "volume": "5",
      "author": "K Shinozaki",
      "year": "1978",
      "unstructured": "Shinozaki K, Okazaki T (1978) T7 gene 6 exonuclease has an RNase H activity. Nucleic Acids Res 5:4245\u20134261",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "BF00330673_CR33",
      "doi-asserted-by": "crossref",
      "first-page": "6096",
      "DOI": "10.1073/pnas.78.10.6096",
      "volume": "78",
      "author": "J Tomizawa",
      "year": "1981",
      "unstructured": "Tomizawa J, Itoh T (1981) Plasmid ColE1 incompatibility determined by interaction of RNA I with primer transcript. Proc Natl Acad Sci USA 78:6096\u20136100",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "BF00330673_CR34",
      "doi-asserted-by": "crossref",
      "first-page": "1421",
      "DOI": "10.1073/pnas.78.3.1421",
      "volume": "78",
      "author": "J Tomizawa",
      "year": "1981",
      "unstructured": "Tomizawa J, Itoh T, Selzer G, Som T (1981) Inhibition of ColE1 RNA primer formation by a plasmic-specified small DNA. Proc Natl Acad Sci USA 78:1421\u20131425",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "BF00330673_CR35",
      "doi-asserted-by": "crossref",
      "first-page": "4085",
      "DOI": "10.1016/S0021-9258(17)33358-6",
      "volume": "251",
      "author": "D Uyemura",
      "year": "1976",
      "unstructured": "Uyemura D, Eichler DC, Lehman IR (1976) Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. II. The polAex1 mutation. J Biol Chem 251:4085\u20134089",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "BF00330673_CR36",
      "doi-asserted-by": "crossref",
      "first-page": "903",
      "DOI": "10.1016/S0021-9258(19)86118-5",
      "volume": "255",
      "author": "S Venkatesan",
      "year": "1980",
      "unstructured": "Venkatesan S, Gershowitz A, Moss B (1980) Modification of the 5\u2032 end of mRNA. J Biol Chem 255:903\u2013908",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "BF00330673_CR37",
      "doi-asserted-by": "crossref",
      "first-page": "11",
      "DOI": "10.1016/0005-2787(79)90122-9",
      "volume": "562",
      "author": "TF Walseth",
      "year": "1979",
      "unstructured": "Walseth TF, Johnson RA (1979) The enzymatic preparation of [\u03b1-32P]nucleoside triphosphates, cyclic [32P]AMP, and cyclic [32P]GMP. Biochim Biophys Acta 562:11\u201331",
      "journal-title": "Biochim Biophys Acta"
    },
    {
      "key": "BF00330673_CR38",
      "doi-asserted-by": "crossref",
      "first-page": "191",
      "DOI": "10.1016/B978-0-12-322650-1.50036-9",
      "volume-title": "DNA repair mechanism",
      "author": "B Weiss",
      "year": "1978",
      "unstructured": "Weiss B, Rogers SG, Taylor AF (1978) The endonuclease activity of exonuclease III and the repair of uracil-containing DNA in Escherichia coli. In: Hanawalt PC, Friedberg EC, Fox CF (eds) DNA repair mechanism. Academic Press, New York, pp 191\u2013194"
    },
    {
      "key": "BF00330673_CR39",
      "doi-asserted-by": "crossref",
      "first-page": "148",
      "DOI": "10.1128/JB.130.1.148-153.1977",
      "volume": "130",
      "author": "DD Womble",
      "year": "1977",
      "unstructured": "Womble DD, Taylor DP, Rownd RH (1977) Method for obtaining more-accurate covalently closed circular plasmid-to-chromosome ratios from bacterial lysates by dye-buoyant density centrifugation. J Bacteriol 130:148\u2013153",
      "journal-title": "J Bacteriol"
    },
    {
      "key": "BF00330673_CR40",
      "doi-asserted-by": "crossref",
      "first-page": "525",
      "DOI": "10.1007/BF00337857",
      "volume": "178",
      "author": "K Yamaguchi",
      "year": "1980",
      "unstructured": "Yamaguchi K, Tomizawa J (1980) Establishement of Escherichia coli cells with an integrated high copy number plasmid. Mol Gen Genet 178:525\u2013533",
      "journal-title": "Mol Gen Genet"
    }
  ],
  "container-title": "Molecular and General Genetics MGG",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "http://link.springer.com/content/pdf/10.1007/BF00330673.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://link.springer.com/article/10.1007/BF00330673/fulltext.html",
      "content-type": "text/html",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://link.springer.com/content/pdf/10.1007/BF00330673",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    },
    {
      "URL": "http://link.springer.com/content/pdf/10.1007/BF00330673.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        6,
        26
      ]
    ],
    "date-time": "2021-06-26T21:33:04Z",
    "timestamp": 1624743184000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "http://link.springer.com/10.1007/BF00330673"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1984,
        2
      ]
    ]
  },
  "references-count": 40,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1984,
          2
        ]
      ]
    }
  },
  "alternative-id": [
    "BF00330673"
  ],
  "URL": "http://dx.doi.org/10.1007/BF00330673",
  "relation": {},
  "ISSN": [
    "0026-8925",
    "1432-1874"
  ],
  "subject": [],
  "container-title-short": "Molec Gen Genet",
  "published": {
    "date-parts": [
      [
        1984,
        2
      ]
    ]
  }
}