DOI: 10.1006/jmbi.2000.4274. Ligand-Induced Strain in Hydrogen Bonds of the c-Src SH3 Domain Detected by NMR

Ligand-Induced Strain in Hydrogen Bonds of the c-Src SH3 Domain Detected by NMR

10.1006/jmbi.2000.4274

Crossref journal-article

Elsevier BV

Journal of Molecular Biology (78)

Bibliography

Cordier, F., Wang, C., Grzesiek, S., & Nicholson, L. K. (2000). Ligand-Induced Strain in Hydrogen Bonds of the c-Src SH3 Domain Detected by NMR. Journal of Molecular Biology, 304(4), 497â505.

Authors 4

Florence Cordier (first)
Chunyu Wang (additional)
Stephan Grzesiek (additional)
Linda K. Nicholson (additional)

References 31 Referenced 58

10.1002/prot.340020102 / Proteins: Struct. Funct. Genet. / Estimation of uncertainties in X-ray refinement results by use of perturbed structures by Kuriyan (1987)
10.1021/ja983945d / J. Am. Chem. Soc. / Direct observation of hydrogen bonds in proteins by interresidue h3JNC′ Scalar Couplings by Cordier (1999)
10.1021/ja9902221 / J. Am. Chem. Soc. / Identification of the hydrogen bonding network in a protein by scalar couplings by Cornilescu (1999)
10.1006/jmre.1999.1998 / J. Magn. Reson. / Title by Meissner (2000)
10.1021/ja9917417 / J. Am. Chem. Soc. / Quantum-chemical characterization of nuclear spin-spin couplings across hydrogen bonds by Scheurer (1999)
10.1021/ja9909024 / J. Am. Chem. Soc. / Correlation between h3JNC′ and hydrogen bond length in proteins by Cornilescu (1999)
10.1126/science.7526465 / Science / Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions by Feng (1994)
10.1021/bi962548h / Biochemistry / Characterization of the backbone dynamics of folded and denatured states of an SH3 domain by Farrow (1997)
10.1038/14901 / Nature Struct. Biol. / Experiment and theory highlight role of native state topology in SH3 folding by Riddle (1999)
10.1038/14896 / Nature Struct. Biol. / The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved by Martinez (1999)
10.1016/0092-8674(94)90367-0 / Cell / Structural basis for the binding of proline-rich peptides to SH3 domains by Yu (1994)
10.1128/MCB.15.10.5627 / Mol. Cell. Biol. / Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions by Weng (1995)
10.1021/bi00202a011 / Biochemistry / Characterization of the interaction of natural proline-rich peptides with five different SH3 domains by Viguera (1994)
10.1016/0014-5793(93)81538-B / FEBS Letters / 1H and 15N assignments and secondary structure of the Src SH3 domain by Yu (1993)
10.1038/385595a0 / Nature / Three-dimensional structure of the tyrosine kinase c-Src by Xu (1997)
10.1016/S1097-2765(00)80356-1 / Mol. Cell / Crystal structures of c-Src reveal features of its autoinhibitory mechanism by Xu (1999)
{'key': '10.1006/jmbi.2000.4274_RF17', 'series-title': 'Mechanical Engineering Design', 'author': 'Shigley', 'year': '1977'} / Mechanical Engineering Design by Shigley (1977)
10.1021/ja00356a056 / J. Am. Chem. Soc. / Hydrogen bond length and proton NMR chemical shifts in proteins by Wagner (1983)
10.1111/j.1432-1033.1983.tb07848.x / Eur. J. Biochem. / Protein conformation and proton nuclear magnetic resonance chemical shifts by Pardi (1983)
10.1021/bi9712044 / Biochemistry / Heteronuclear NMR studies of the combined Src homology domains 2 and 3 of pp60 c-Src: effects of phosphopeptide binding by Tessari (1997)
{'key': '10.1006/jmbi.2000.4274_RF21', 'series-title': 'Structure, Motion, Interaction and Expression of Biological Macromolecules. Proceedings of the Tenth Conversation, State University of New York, Albany, NY 1997', 'article-title': 'Mechanisms of regulation in the regulatory apparatus of pp60 c-Src', 'author': 'Reinking', 'year': '1998'} / Structure, Motion, Interaction and Expression of Biological Macromolecules. Proceedings of the Tenth Conversation, State University of New York, Albany, NY 1997 / Mechanisms of regulation in the regulatory apparatus of pp60 c-Src by Reinking (1998)
10.1016/S0968-0004(98)01202-X / Trends Biochem Sci. / Insights into Src kinase functions: structural comparisons by Williams (1998)
10.1074/jbc.271.15.8959 / J. Biol. Chem. / Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase by Nakamoto (1996)
10.1038/368867a0 / Nature / An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis by Taylor (1994)
10.1038/368871a0 / Nature / A target for Src in mitosis by Fumagalli (1994)
10.1101/gad.10.11.1341 / Genes Dev. / Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin by Alexandropoulos (1996)
10.1074/jbc.273.1.577 / J. Biol. Chem. / SH2- and SH3-mediated interactions between focal adhesion kinase and Src by Thomas (1998)
10.1021/bi981352+ / Biochemistry / Identification of the binding surface on Cdc42Hs for p21-activated kinase by Guo (1998)
10.1023/A:1008346517302 / J. Biomol. NMR / Measurement of h3JNC′ connectivities across hydrogen bonds in a 30kDa protein by Wang (1999)
10.1021/ja9908321 / J. Am. Chem. Soc. / Internucleotide scalar couplings across hydrogen bonds in watson-crick and hoogsteen base pairs of a DNA triplex by Dingley (1999)
{'key': '10.1006/jmbi.2000.4274_RF31', 'series-title': 'X-PLOR (version 3.1) A System for X-ray Crystallography and NMR', 'author': 'Brünger', 'year': '1992'} / X-PLOR (version 3.1) A System for X-ray Crystallography and NMR by Brünger (1992)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 18, 2002, 3:24 p.m.)
Deposited	6 years, 3 months ago (May 8, 2019, 12:20 p.m.)
Indexed	2 months, 1 week ago (June 26, 2025, 9:28 a.m.)
Issued	24 years, 9 months ago (Dec. 1, 2000)
Published	24 years, 9 months ago (Dec. 1, 2000)
Published Print	24 years, 9 months ago (Dec. 1, 2000)

Funders 0

None

BibTeX

@article{Cordier_2000, title={Ligand-Induced Strain in Hydrogen Bonds of the c-Src SH3 Domain Detected by NMR}, volume={304}, ISSN={0022-2836}, url={http://dx.doi.org/10.1006/jmbi.2000.4274}, DOI={10.1006/jmbi.2000.4274}, number={4}, journal={Journal of Molecular Biology}, publisher={Elsevier BV}, author={Cordier, Florence and Wang, Chunyu and Grzesiek, Stephan and Nicholson, Linda K.}, year={2000}, month=dec, pages={497–505} }

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