DOI: 10.1006/jmbi.2000.4190. Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction 1 1Edited by A. Fersht

Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction 1 1Edited by A. Fersht

10.1006/jmbi.2000.4190

Crossref journal-article

Elsevier BV

Journal of Molecular Biology (78)

Bibliography

Choe, S. E., Li, L., Matsudaira, P. T., Wagner, G., & Shakhnovich, E. I. (2000). Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction 1 1Edited by A. Fersht. Journal of Molecular Biology, 304(1), 99â115.

Authors 5

Sung E. Choe (first)
Lewyn Li (additional)
Paul T. Matsudaira (additional)
Gerhard Wagner (additional)
Eugene I. Shakhnovich (additional)

References 40 Referenced 19

10.1021/bi00199a029 / Biochemistry / Specific nucleus as the transition state for protein folding by Abkevich (1994)
10.1016/S0959-440X(99)80027-X / Curr. Opin. Struct. Biol. / Matching theory and experiment in protein folding by Alm (1999)
{'key': '10.1006/jmbi.2000.4190_BIB3', 'volume': 'vol. 1', 'author': 'Ausubel', 'year': '1987'} by Ausubel (1987)
10.1038/14890 / Nature Struct. Biol. / Mutational analysis of acylphosphatase suggests the importance of topology and contact order in protein folding by Chiti (1999)
10.1021/bi980889k / Biochemistry / Folding kinetics of villin 14T, a protein domain with a central beta-sheet and two hydrophobic cores by Choe (1998)
10.1016/S0969-2126(99)80181-6 / Structure / Folding studies of immunoglobulin-like β-sandwich proteins suggest that they share a common folding pathway by Clarke (1999)
10.1021/bi9615699 / Biochemistry / Cysteine scanning mutagenesis at 40 of 76 positions in villin headpiece maps the F-actin binding site and structural features of the domain by Doering (1996)
10.1016/0022-2836(92)90561-W / J. Mol. Biol. / The folding of an enzyme. I. Theory of protein engineering analysis of stability and pathway of protein folding by Fersht (1992)
10.1073/pnas.91.22.10426 / Proc. Natl Acad. Sci. USA / Single versus parallel pathways of protein folding and fractional formation of structure in the transition state by Fersht (1994)
10.1006/jmbi.1999.2942 / J. Mol. Biol. / Mapping the interactions present in the transition state for unfolding/folding of FKBP12 by Fulton (1999)
10.1038/1412 / Nature Struct. Biol. / Important role of hydrogen bonds in the structurally polarized transition state for folding of the src SH3 domain by Grantcharova (1998)
10.1006/jmbi.2000.3517 / J. Mol. Biol. / The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology by Hamill (2000)
10.1073/pnas.96.20.11247 / Proc. Natl Acad. Sci. USA / Equilibria and kinetics of folding of gelsolin domain 2 and mutants involved in familial amyloidosis-Finnish type by Isaacson (1999)
10.1006/jmbi.1995.0616 / J. Mol. Biol. / The structure of the transition state for folding of chymotrypsin inhibitor 2 analysed by protein engineering methods by Itzhaki (1995)
10.1016/S1359-0278(98)00033-9 / Fold. Design / How do small single-domain proteins fold? by Jackson (1998)
10.1021/bi00107a010 / Biochemistry / Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition by Jackson (1991)
10.1021/bi00107a011 / Biochemistry / Folding of chymotrypsin inhibitor 2. 2. Influence of proline isomerization on the folding kinetics and thermodynamic characterization of the transition state of folding by Jackson (1991)
10.1021/bi00093a002 / Biochemistry / Structure of the hydrophobic core in the transition state for folding of chymotrypsin inhibitor 2 by Jackson (1993)
10.1038/nsb0296-193 / Nature Struct. Biol. / Evidence for a three-state model of protein folding from kinetic analysis of ubiquitin variants with altered core residues by Khorasanizadeh (1996)
10.1006/jmbi.2000.3701 / J. Mol. Biol. / A breakdown of symmetry in the folding transition state of protein L by Kim (2000)
10.1146/annurev.bi.59.070190.003215 / Annu. Rev. Biochem. / Intermediates in the folding reactions of small proteins by Kim (1990)
10.1038/9384 / Nature Struct. Biol. / The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP by Kragelund (1999)
10.1107/S0021889891004399 / J. Appl. Crystallog. / MOLSCRIPT by Kraulis (1991)
{'key': '10.1006/jmbi.2000.4190_BIB24', 'first-page': '44', 'article-title': 'Are there pathways for protein folding?', 'volume': '65', 'author': 'Levinthal', 'year': '1968', 'journal-title': 'J. Chem. Phys.'} / J. Chem. Phys. / Are there pathways for protein folding? by Levinthal (1968)
10.1016/S1359-0278(96)00011-9 / Fold. Design / Structure of the transition state for folding of the 129aa protein CheY resembles that of a smaller protein, CI-2 by Lopez-Hernandez (1996)
10.1002/pro.5560030110 / Protein Sci. / Solution structure of villin 14T, a domain conserved among actin-severing proteins by Markus (1994)
10.1002/pro.5560060608 / Protein Sci. / Refined structure of villin 14T and a detailed comparison with other actin-severing domains by Markus (1997)
10.1038/14896 / Nature Struct. Biol. / The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved by Martinez (1999)
10.1073/pnas.90.16.7814 / Proc. Natl Acad. Sci. USA / Application of physical organic chemistry to engineered mutants of proteins by Matouschek (1993)
10.1021/bi00042a024 / Biochemistry / P22 Arc repressor by Milla (1995)
10.1006/jmbi.1999.2911 / J. Mol. Biol. / Universally conserved positions in protein folds by Mirny (1999)
10.1073/pnas.95.9.4976 / Proc. Natl Acad. Sci. USA / How evolution makes proteins fold quickly by Mirny (1998)
10.1021/bi982819j / Biochemistry / Structural changes in the transition state of protein folding by Otzen (1999)
10.1038/14901 / Nature Struct. Biol. / Experiment and theory highlight role of native state topology in SH3 folding by Riddle (1999)
10.1016/0022-2836(92)90563-Y / J. Mol. Biol. / The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering procedure by Serrano (1992)
10.1038/379096a0 / Nature / Conserved residues and the mechanism of protein folding by Shakhnovich (1996)
10.1016/S0065-3233(08)60336-8 / Advan. Protein Chem. / Staphylococcal nuclease by Shortle (1995)
10.1038/nsb1096-874 / Nature Struct. Biol. / Different folding transition states may result in the same native structure by Viguera (1996)
10.1006/jmbi.1998.2158 / J. Mol. Biol. / Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain by Villegas (1998)
10.1038/12338 / Nature Struct. Biol. / A model of the changes in denatured state structure underlying m value effects in staphylococcal nuclease by Wrabl (1999)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 18, 2002, 11:24 a.m.)
Deposited	6 years, 3 months ago (May 8, 2019, 3:53 p.m.)
Indexed	1 year, 10 months ago (Oct. 13, 2023, 7:31 p.m.)
Issued	24 years, 10 months ago (Nov. 1, 2000)
Published	24 years, 10 months ago (Nov. 1, 2000)
Published Print	24 years, 10 months ago (Nov. 1, 2000)

Funders 0

None

BibTeX

@article{Choe_2000, title={Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction 1 1Edited by A. Fersht}, volume={304}, ISSN={0022-2836}, url={http://dx.doi.org/10.1006/jmbi.2000.4190}, DOI={10.1006/jmbi.2000.4190}, number={1}, journal={Journal of Molecular Biology}, publisher={Elsevier BV}, author={Choe, Sung E. and Li, Lewyn and Matsudaira, Paul T. and Wagner, Gerhard and Shakhnovich, Eugene I.}, year={2000}, month=nov, pages={99–115} }

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      "first-page": "14508",
      "DOI": "10.1021/bi980889k",
      "article-title": "Folding kinetics of villin 14T, a protein domain with a central beta-sheet and two hydrophobic cores",
      "volume": "37",
      "author": "Choe",
      "year": "1998",
      "journal-title": "Biochemistry"
    },
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      "first-page": "1145",
      "DOI": "10.1016/S0969-2126(99)80181-6",
      "article-title": "Folding studies of immunoglobulin-like \u03b2-sandwich proteins suggest that they share a common folding pathway",
      "volume": "7",
      "author": "Clarke",
      "year": "1999",
      "journal-title": "Structure"
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    {
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      "first-page": "12677",
      "DOI": "10.1021/bi9615699",
      "article-title": "Cysteine scanning mutagenesis at 40 of 76 positions in villin headpiece maps the F-actin binding site and structural features of the domain",
      "volume": "35",
      "author": "Doering",
      "year": "1996",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "771",
      "DOI": "10.1016/0022-2836(92)90561-W",
      "article-title": "The folding of an enzyme. I. Theory of protein engineering analysis of stability and pathway of protein folding",
      "volume": "224",
      "author": "Fersht",
      "year": "1992",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "10426",
      "DOI": "10.1073/pnas.91.22.10426",
      "article-title": "Single versus parallel pathways of protein folding and fractional formation of structure in the transition state",
      "volume": "91",
      "author": "Fersht",
      "year": "1994",
      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
    {
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      "first-page": "445",
      "DOI": "10.1006/jmbi.1999.2942",
      "article-title": "Mapping the interactions present in the transition state for unfolding/folding of FKBP12",
      "volume": "291",
      "author": "Fulton",
      "year": "1999",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "714",
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      "article-title": "Important role of hydrogen bonds in the structurally polarized transition state for folding of the src SH3 domain",
      "volume": "5",
      "author": "Grantcharova",
      "year": "1998",
      "journal-title": "Nature Struct. Biol."
    },
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      "volume": "297",
      "author": "Hamill",
      "year": "2000",
      "journal-title": "J. Mol. Biol."
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      "article-title": "Equilibria and kinetics of folding of gelsolin domain 2 and mutants involved in familial amyloidosis-Finnish type",
      "volume": "96",
      "author": "Isaacson",
      "year": "1999",
      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "260",
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      "article-title": "The structure of the transition state for folding of chymotrypsin inhibitor 2 analysed by protein engineering methods",
      "volume": "254",
      "author": "Itzhaki",
      "year": "1995",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "R81",
      "DOI": "10.1016/S1359-0278(98)00033-9",
      "article-title": "How do small single-domain proteins fold?",
      "volume": "3",
      "author": "Jackson",
      "year": "1998",
      "journal-title": "Fold. Design"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "10428",
      "DOI": "10.1021/bi00107a010",
      "article-title": "Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition",
      "volume": "30",
      "author": "Jackson",
      "year": "1991",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "10436",
      "DOI": "10.1021/bi00107a011",
      "article-title": "Folding of chymotrypsin inhibitor 2. 2. Influence of proline isomerization on the folding kinetics and thermodynamic characterization of the transition state of folding",
      "volume": "30",
      "author": "Jackson",
      "year": "1991",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "11270",
      "DOI": "10.1021/bi00093a002",
      "article-title": "Structure of the hydrophobic core in the transition state for folding of chymotrypsin inhibitor 2",
      "volume": "32",
      "author": "Jackson",
      "year": "1993",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "193",
      "DOI": "10.1038/nsb0296-193",
      "article-title": "Evidence for a three-state model of protein folding from kinetic analysis of ubiquitin variants with altered core residues",
      "volume": "3",
      "author": "Khorasanizadeh",
      "year": "1996",
      "journal-title": "Nature Struct. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "971",
      "DOI": "10.1006/jmbi.2000.3701",
      "article-title": "A breakdown of symmetry in the folding transition state of protein L",
      "volume": "298",
      "author": "Kim",
      "year": "2000",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "631",
      "DOI": "10.1146/annurev.bi.59.070190.003215",
      "article-title": "Intermediates in the folding reactions of small proteins",
      "volume": "59",
      "author": "Kim",
      "year": "1990",
      "journal-title": "Annu. Rev. Biochem."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "594",
      "DOI": "10.1038/9384",
      "article-title": "The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP",
      "volume": "6",
      "author": "Kragelund",
      "year": "1999",
      "journal-title": "Nature Struct. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "946",
      "DOI": "10.1107/S0021889891004399",
      "article-title": "MOLSCRIPT",
      "volume": "24",
      "author": "Kraulis",
      "year": "1991",
      "journal-title": "J. Appl. Crystallog."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB24",
      "first-page": "44",
      "article-title": "Are there pathways for protein folding?",
      "volume": "65",
      "author": "Levinthal",
      "year": "1968",
      "journal-title": "J. Chem. Phys."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "43",
      "DOI": "10.1016/S1359-0278(96)00011-9",
      "article-title": "Structure of the transition state for folding of the 129aa protein CheY resembles that of a smaller protein, CI-2",
      "volume": "l",
      "author": "Lopez-Hernandez",
      "year": "1996",
      "journal-title": "Fold. Design"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "70",
      "DOI": "10.1002/pro.5560030110",
      "article-title": "Solution structure of villin 14T, a domain conserved among actin-severing proteins",
      "volume": "3",
      "author": "Markus",
      "year": "1994",
      "journal-title": "Protein Sci."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "1197",
      "DOI": "10.1002/pro.5560060608",
      "article-title": "Refined structure of villin 14T and a detailed comparison with other actin-severing domains",
      "volume": "6",
      "author": "Markus",
      "year": "1997",
      "journal-title": "Protein Sci."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "1010",
      "DOI": "10.1038/14896",
      "article-title": "The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved",
      "volume": "6",
      "author": "Martinez",
      "year": "1999",
      "journal-title": "Nature Struct. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "7814",
      "DOI": "10.1073/pnas.90.16.7814",
      "article-title": "Application of physical organic chemistry to engineered mutants of proteins",
      "volume": "90",
      "author": "Matouschek",
      "year": "1993",
      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "13914",
      "DOI": "10.1021/bi00042a024",
      "article-title": "P22 Arc repressor",
      "volume": "34",
      "author": "Milla",
      "year": "1995",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "177",
      "DOI": "10.1006/jmbi.1999.2911",
      "article-title": "Universally conserved positions in protein folds",
      "volume": "291",
      "author": "Mirny",
      "year": "1999",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "4976",
      "DOI": "10.1073/pnas.95.9.4976",
      "article-title": "How evolution makes proteins fold quickly",
      "volume": "95",
      "author": "Mirny",
      "year": "1998",
      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "6499",
      "DOI": "10.1021/bi982819j",
      "article-title": "Structural changes in the transition state of protein folding",
      "volume": "38",
      "author": "Otzen",
      "year": "1999",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "1016",
      "DOI": "10.1038/14901",
      "article-title": "Experiment and theory highlight role of native state topology in SH3 folding",
      "volume": "6",
      "author": "Riddle",
      "year": "1999",
      "journal-title": "Nature Struct. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.4190_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "805",
      "DOI": "10.1016/0022-2836(92)90563-Y",
      "article-title": "The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering procedure",
      "volume": "224",
      "author": "Serrano",
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      "author": "Shortle",
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      "author": "Viguera",
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      "journal-title": "Nature Struct. Biol."
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      "volume": "283",
      "author": "Villegas",
      "year": "1998",
      "journal-title": "J. Mol. Biol."
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      "DOI": "10.1038/12338",
      "article-title": "A model of the changes in denatured state structure underlying m value effects in staphylococcal nuclease",
      "volume": "6",
      "author": "Wrabl",
      "year": "1999",
      "journal-title": "Nature Struct. Biol."
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