DOI: 10.1006/jmbi.2000.3860. Modeling of substrate specificity of the Alzheimer’s disease amyloid precursor protein β-secretase 1 1Edited by F. E. Cohen

Modeling of substrate specificity of the Alzheimer’s disease amyloid precursor protein β-secretase 1 1Edited by F. E. Cohen

10.1006/jmbi.2000.3860

Crossref journal-article

Elsevier BV

Journal of Molecular Biology (78)

Bibliography

Sauder, J. M., Arthur, J. W., & Dunbrack, R. L. (2000). Modeling of substrate specificity of the Alzheimerâs disease amyloid precursor protein Î²-secretase 1 1Edited by F. E. Cohen. Journal of Molecular Biology, 300(2), 241â248.

Authors 3

J.Michael Sauder (first)
Jonathan W. Arthur (additional)
Roland L. Dunbrack (additional)

References 30 Referenced 41

10.1093/nar/25.17.3389 / Nucl. Acids Res. / Gapped BLAST and PSI-BLAST by Altschul (1997)
10.1111/j.1432-1033.1997.t01-1-00171.x / Eur. J. Biochem. / Substrate specificity of cathepsins D and E determined by N-terminal and C-terminal sequencing of peptide pools by Arnold (1997)
10.1006/jmbi.1997.0926 / J. Mol. Biol. / Prediction of protein side-chain rotamers from a backbone-dependent rotamer library by Bower (1997)
10.1126/science.8424174 / Science / Release of excess amyloid β protein from a mutant amyloid β precursor by Cai (1993)
10.1016/0896-6273(95)90323-2 / Neuron / Generation of amyloid beta protein from its precursor is sequence specific by Citron (1995)
10.1002/(SICI)1097-0134(1999)37:3+<81::AID-PROT12>3.0.CO;2-R / Proteins: Struct. Funct. Genet. / Comparative modeling of CASP3 targets using PS-BLAST and SCWRL by Dunbrack (1999)
10.1002/pro.5560060807 / Protein Sci. / Bayesian statistical analysis of protein side-chain rotamer preferences by Dunbrack (1997)
10.1016/0263-7855(88)80054-7 / J. Mol. Graph. / The MIDAS display system by Ferrin (1988)
10.1002/prot.340230412 / Proteins: Struct. Funct. Genet. / Knowledge-based protein secondary structure assignment by Frishman (1995)
10.1002/pro.5560040516 / Protein Sci. / Crystal structure of human pepsin and its complex with pepstatin by Fujinaga (1995)
10.1016/S0006-291X(84)80190-4 / Biochem. Biophys. Res. Commun. / Alzheimer’s disease by Glenner (1984)
10.1046/j.1471-4159.1998.71051920.x / J. Neurochem. / Generation and regulation of beta-amyloid peptide variants by neurons by Gouras (1998)
10.1093/nar/26.1.316 / Nucl. Acids Res. / Touring protein fold space with Dali/FSSP by Holm (1998)
10.1006/mcne.1999.0811 / Mol. Cell. Neurosci. / Identification of a novel aspartic protease (Asp2) as β secretase by Hussain (1999)
10.1042/bj2650871 / Biochem. J. / The selectivity of statine-based inhibitors against various human aspartic proteinases by Jupp (1999)
10.1038/325733a0 / Nature / The precursor of Alzheimer’s disease amyloid A4 protein resembles a cell surface receptor by Kang (1987)
10.1107/S0021889891004399 / J. Appl. Crystallog. / MOLSCRIPT by Kraulis (1991)
10.1073/pnas.96.6.3053 / Proc. Natl Acad. Sci. USA / Mechanism of the cleavage specificity of Alzheimer’s disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein by Lichtenthaler (1999)
10.1073/pnas.96.21.12108 / Proc. Natl Acad. Sci. USA / Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation by Lin (1999)
{'key': '10.1006/jmbi.2000.3860_BIB29', 'series-title': 'The GNU image manipulation program. Ver. 1.0.4', 'author': 'Mattis', 'year': '1998'} / The GNU image manipulation program. Ver. 1.0.4 by Mattis (1998)
10.1006/jmbi.1994.1334 / J. Mol. Biol. / Satisfying hydrogen bonding potential in proteins by McDonald (1994)
10.1016/S0076-6879(97)77028-9 / Methods Enzymol. / Raster3D photorealistic molecular graphics by Merritt (1997)
10.1002/jnr.490390415 / J. Neurosci. Res. / Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer’s disease research by Neill (1994)
10.1038/72477 / Nature Biotechnol. / The potential of BACE inhibitors for Alzheimer’s therapy by Potter (2000)
10.1002/(SICI)1097-0134(20000701)40:1<6::AID-PROT30>3.0.CO;2-7 / Proteins: Struct. Funct. Genet. / Large-scale comparison of protein sequence alignment algorithms with structure alignments by Sauder (2000)
10.1126/science.286.5443.1255a / Science / BACE maps to chromosome 11 and a BACE homolog, BACE2, reside in the obligate down syndrome region of chromosome 21 by Saunders (1999)
10.1038/990114 / Nature / Purification and cloning of amyloid precursor protein beta-secretase from human brain by Sinha (1999)
10.1073/pnas.84.20.7009 / Proc. Natl Acad. Sci. USA / Binding of a reduced peptide inhibitor to the aspartic proteinase from Rhizopus chinensis by Suguna (1987)
10.1126/science.286.5440.735 / Science / β-Secretase cleavage of Alzheimer’s amyloid precursor protein by the transmembrane aspartic protease BACE by Vassar (1999)
10.1038/990107 / Nature / Membrane-anchored aspartyl protease with Alzheimer’s disease beta-secretase activity by Yan (1999)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 18, 2002, 11:24 a.m.)
Deposited	6 years, 3 months ago (May 8, 2019, 1:50 a.m.)
Indexed	11 months, 1 week ago (Sept. 20, 2024, 11:30 a.m.)
Issued	25 years, 2 months ago (July 1, 2000)
Published	25 years, 2 months ago (July 1, 2000)
Published Print	25 years, 2 months ago (July 1, 2000)

Funders 0

None

BibTeX

@article{Sauder_2000, title={Modeling of substrate specificity of the Alzheimer’s disease amyloid precursor protein β-secretase 1 1Edited by F. E. Cohen}, volume={300}, ISSN={0022-2836}, url={http://dx.doi.org/10.1006/jmbi.2000.3860}, DOI={10.1006/jmbi.2000.3860}, number={2}, journal={Journal of Molecular Biology}, publisher={Elsevier BV}, author={Sauder, J.Michael and Arthur, Jonathan W. and Dunbrack, Roland L.}, year={2000}, month=jul, pages={241–248} }

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      "article-title": "Generation of amyloid beta protein from its precursor is sequence specific",
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      "author": "Citron",
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      "volume": "3",
      "author": "Dunbrack",
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      "journal-title": "Proteins: Struct. Funct. Genet."
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      "first-page": "13",
      "DOI": "10.1016/0263-7855(88)80054-7",
      "article-title": "The MIDAS display system",
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      "author": "Ferrin",
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      "journal-title": "J. Mol. Graph."
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    {
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      "doi-asserted-by": "crossref",
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      "journal-title": "Proteins: Struct. Funct. Genet."
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      "author": "Fujinaga",
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      "journal-title": "Protein Sci."
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      "first-page": "885",
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      "article-title": "Alzheimer\u2019s disease",
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      "author": "Glenner",
      "year": "1984",
      "journal-title": "Biochem. Biophys. Res. Commun."
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      "author": "Gouras",
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      "author": "Hussain",
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      "author": "Jupp",
      "year": "1999",
      "journal-title": "Biochem. J."
    },
    {
      "key": "10.1006/jmbi.2000.3860_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "733",
      "DOI": "10.1038/325733a0",
      "article-title": "The precursor of Alzheimer\u2019s disease amyloid A4 protein resembles a cell surface receptor",
      "volume": "325",
      "author": "Kang",
      "year": "1987",
      "journal-title": "Nature"
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      "article-title": "MOLSCRIPT",
      "volume": "24",
      "author": "Kraulis",
      "year": "1991",
      "journal-title": "J. Appl. Crystallog."
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      "article-title": "Mechanism of the cleavage specificity of Alzheimer\u2019s disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein",
      "volume": "96",
      "author": "Lichtenthaler",
      "year": "1999",
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      "article-title": "Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation",
      "volume": "96",
      "author": "Lin",
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      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
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      "key": "10.1006/jmbi.2000.3860_BIB29",
      "series-title": "The GNU image manipulation program. Ver. 1.0.4",
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      "DOI": "10.1006/jmbi.1994.1334",
      "article-title": "Satisfying hydrogen bonding potential in proteins",
      "volume": "238",
      "author": "McDonald",
      "year": "1994",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.2000.3860_BIB20",
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      "DOI": "10.1016/S0076-6879(97)77028-9",
      "article-title": "Raster3D photorealistic molecular graphics",
      "volume": "277",
      "author": "Merritt",
      "year": "1997",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "10.1006/jmbi.2000.3860_BIB21",
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      "first-page": "482",
      "DOI": "10.1002/jnr.490390415",
      "article-title": "Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer\u2019s disease research",
      "volume": "39",
      "author": "Neill",
      "year": "1994",
      "journal-title": "J. Neurosci. Res."
    },
    {
      "key": "10.1006/jmbi.2000.3860_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "125",
      "DOI": "10.1038/72477",
      "article-title": "The potential of BACE inhibitors for Alzheimer\u2019s therapy",
      "volume": "18",
      "author": "Potter",
      "year": "2000",
      "journal-title": "Nature Biotechnol."
    },
    {
      "key": "10.1006/jmbi.2000.3860_BIB23",
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      "first-page": "6",
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      "article-title": "Large-scale comparison of protein sequence alignment algorithms with structure alignments",
      "volume": "40",
      "author": "Sauder",
      "year": "2000",
      "journal-title": "Proteins: Struct. Funct. Genet."
    },
    {
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      "first-page": "1255a",
      "DOI": "10.1126/science.286.5443.1255a",
      "article-title": "BACE maps to chromosome 11 and a BACE homolog, BACE2, reside in the obligate down syndrome region of chromosome 21",
      "volume": "286",
      "author": "Saunders",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/jmbi.2000.3860_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "537",
      "DOI": "10.1038/990114",
      "article-title": "Purification and cloning of amyloid precursor protein beta-secretase from human brain",
      "volume": "402",
      "author": "Sinha",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/jmbi.2000.3860_BIB26",
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      "first-page": "7009",
      "DOI": "10.1073/pnas.84.20.7009",
      "article-title": "Binding of a reduced peptide inhibitor to the aspartic proteinase from Rhizopus chinensis",
      "volume": "84",
      "author": "Suguna",
      "year": "1987",
      "journal-title": "Proc. Natl Acad. Sci. USA"
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      "first-page": "735",
      "DOI": "10.1126/science.286.5440.735",
      "article-title": "\u03b2-Secretase cleavage of Alzheimer\u2019s amyloid precursor protein by the transmembrane aspartic protease BACE",
      "volume": "286",
      "author": "Vassar",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/jmbi.2000.3860_BIB28",
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      "first-page": "533",
      "DOI": "10.1038/990107",
      "article-title": "Membrane-anchored aspartyl protease with Alzheimer\u2019s disease beta-secretase activity",
      "volume": "402",
      "author": "Yan",
      "year": "1999",
      "journal-title": "Nature"
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