DOI: 10.1006/jmbi.1997.1552. Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 s rRNA

Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 s rRNA

10.1006/jmbi.1997.1552

Crossref journal-article

Elsevier BV

Journal of Molecular Biology (78)

Bibliography

Fourmy, D., Recht, M. I., & Puglisi, J. D. (1998). Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 s rRNA. Journal of Molecular Biology, 277(2), 347â362.

Authors 3

Dominique Fourmy (first)
Michael I Recht (additional)
Joseph D Puglisi (additional)

References 27 Referenced 183

10.1128/AAC.4.4.402 / Antimicrob. Ag. Chemother. / Structure-activity relationships among the aminoglycoside antibiotics by Benveniste (1973)
10.1021/bi00487a027 / Biochemistry / Assignment of the side-chain 1H and 13C resonances of Interleukin-1b using double and triple-resonance heteronuclear three-dimensional NMR spectroscopy by Clore (1990)
10.1016/S0021-9258(18)93308-9 / J. Biol. Chem. / Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics by Davies (1968)
{'key': '10.1006/jmbi.1997.1552_BIB4', 'first-page': '93', 'article-title': 'Misreading of RNA codewords induced by aminoglycoside antibiotics', 'volume': '1', 'author': 'Davies', 'year': '1965', 'journal-title': 'Mol. Pharmacol.'} / Mol. Pharmacol. / Misreading of RNA codewords induced by aminoglycoside antibiotics by Davies (1965)
10.1016/S0022-2836(66)80075-X / J. Mol. Biol. / A further study of misreading of codons induced by streptomycin and neomycin using ribopolynucleotides containing two nucleotides in alternating sequence as templates by Davies (1966)
10.1016/0022-2836(90)90309-A / J. Mol. Biol. / Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16 S ribosomal RNA by DeStasio (1990)
10.1126/science.274.5291.1367 / Science / Structure of the A site of E. coli 16 S rRNA complexed with an aminoglycoside antibiotic by Fourmy (1996)
10.1006/jmbi.1997.1551 / J. Mol. Biol. / Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA by Fourmy (1998)
{'key': '10.1006/jmbi.1997.1552_BIB9', 'series-title': 'The Molecular Basis of Antibiotic Action', 'author': 'Gale', 'year': '1981'} / The Molecular Basis of Antibiotic Action by Gale (1981)
10.1016/0014-5793(94)00740-3 / FEBS Letters / A pulsed field gradient isotope-filtered 3D 13C HMQC-NOESY experiment for extracting intermolecular NOE contacts in molecular complexes by Lee (1994)
{'key': '10.1006/jmbi.1997.1552_BIB11', 'series-title': 'Nitrogen-15 Nuclear Magnetic Resonance Spectroscopy', 'article-title': 'Nitrogen-15 nuclear magnetic resonance spectroscopy', 'author': 'Levy', 'year': '1979'} / Nitrogen-15 Nuclear Magnetic Resonance Spectroscopy / Nitrogen-15 nuclear magnetic resonance spectroscopy by Levy (1979)
10.1021/ja00084a095 / J. Am. Chem. Soc. / Correlation of adenine H2/H8 resonances in uniformly 13C labeled RNAs by 2D HCCH-TOCSY by Marino (1994)
10.1021/ja00093a073 / J. Am. Chem. Soc. / A three-dimensional triple-resonance 1H, 13C, 31P experiment by Marino (1994)
10.1016/0092-8674(86)90813-5 / Cell / Transfer RNA shields specific nucleotides in 16 S ribosomal RNA from attack by chemical probes by Moazed (1986)
10.1038/327389a0 / Nature / Interaction of antibiotics with functional sites in 16 S ribosomal RNA by Moazed (1987)
10.1016/0022-2836(90)90016-F / J. Mol. Biol. / Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA by Moazed (1990)
10.1016/0022-2836(86)90441-9 / J. Mol. Biol. / Rapid chemical probing of conformation in 16 S ribosomal RNA and 30 S ribosomal subunits using primer extension by Moazed (1986)
10.1021/ja00150a001 / J. Am. Chem. Soc. / Improved RNA structure determination by detection of NOE contacts to exchange-broadened amino protons by Mueller (1995)
10.1017/S0033583500005412 / Quart. Rev. Biophys. / Heteronuclear filters in two-dimensional [1H-1H]-NMR spectroscopy by Otting (1990)
10.1016/S0076-6879(95)61016-2 / Methods Enzymol. / Biochemical and NMR studies of RNA conformation with an emphasis on RNA pseudoknots by Puglisi (1995)
10.1006/jmbi.1996.0526 / J. Mol. Biol. / RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide by Recht (1996)
{'key': '10.1006/jmbi.1997.1552_BIB22', 'first-page': '202', 'article-title': 'A constant-time 2D overbodenhausen experiment for inverse correlation of isotopically enriched species', 'volume': '97', 'author': 'Santoro', 'year': '1992', 'journal-title': 'J. Magn. Reson.'} / J. Magn. Reson. / A constant-time 2D overbodenhausen experiment for inverse correlation of isotopically enriched species by Santoro (1992)
10.1016/0014-5793(86)81539-3 / FEBS Letters / Assignment of the 31P and 1H resonances in oligonucleotides by two-dimensional NMR spectroscopy by Sklénar (1986)
10.1021/ja00064a043 / J. Am. Chem. Soc. / Solvent suppression with symmetrically-shifted pulses by Smallcombe (1993)
10.1016/S0076-6879(88)64064-X / Methods Enzymol. / Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension by Stern (1988)
10.1021/ja00024a044 / J. Am. Chem. Soc. / Carbon assignments and heteronuclear coupling constants for an RNA oligonucleotide form natural abundance 13C-1H correlated experiments by Varani (1991)
10.1002/j.1460-2075.1991.tb07863.x / EMBO J. / Interaction of antibiotics with A and P-site-specific bases in 16 S ribosomal RNA by Woodcock (1991)

Dates

Type	When
Created	22 years, 10 months ago (Oct. 7, 2002, 12:30 p.m.)
Deposited	2 years, 4 months ago (April 4, 2023, 10:15 a.m.)
Indexed	1 week, 5 days ago (Aug. 21, 2025, 2:21 p.m.)
Issued	27 years, 6 months ago (March 1, 1998)
Published	27 years, 6 months ago (March 1, 1998)
Published Print	27 years, 6 months ago (March 1, 1998)

Funders 0

None

BibTeX

@article{Fourmy_1998, title={Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 s rRNA}, volume={277}, ISSN={0022-2836}, url={http://dx.doi.org/10.1006/jmbi.1997.1552}, DOI={10.1006/jmbi.1997.1552}, number={2}, journal={Journal of Molecular Biology}, publisher={Elsevier BV}, author={Fourmy, Dominique and Recht, Michael I and Puglisi, Joseph D}, year={1998}, month=mar, pages={347–362} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        21
      ]
    ],
    "date-time": "2025-08-21T18:21:11Z",
    "timestamp": 1755800471624
  },
  "reference-count": 27,
  "publisher": "Elsevier BV",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1998,
            3,
            1
          ]
        ],
        "date-time": "1998-03-01T00:00:00Z",
        "timestamp": 888710400000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1998,
        3
      ]
    ]
  },
  "DOI": "10.1006/jmbi.1997.1552",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        10,
        7
      ]
    ],
    "date-time": "2002-10-07T16:30:16Z",
    "timestamp": 1034008216000
  },
  "page": "347-362",
  "source": "Crossref",
  "is-referenced-by-count": 183,
  "title": "Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 s rRNA",
  "prefix": "10.1006",
  "volume": "277",
  "author": [
    {
      "given": "Dominique",
      "family": "Fourmy",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Michael I",
      "family": "Recht",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Joseph D",
      "family": "Puglisi",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1006/jmbi.1997.1552_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "402",
      "DOI": "10.1128/AAC.4.4.402",
      "article-title": "Structure-activity relationships among the aminoglycoside antibiotics",
      "volume": "4",
      "author": "Benveniste",
      "year": "1973",
      "journal-title": "Antimicrob. Ag. Chemother."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "8172",
      "DOI": "10.1021/bi00487a027",
      "article-title": "Assignment of the side-chain 1H and 13C resonances of Interleukin-1b using double and triple-resonance heteronuclear three-dimensional NMR spectroscopy",
      "volume": "29",
      "author": "Clore",
      "year": "1990",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "3312",
      "DOI": "10.1016/S0021-9258(18)93308-9",
      "article-title": "Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics",
      "volume": "243",
      "author": "Davies",
      "year": "1968",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB4",
      "first-page": "93",
      "article-title": "Misreading of RNA codewords induced by aminoglycoside antibiotics",
      "volume": "1",
      "author": "Davies",
      "year": "1965",
      "journal-title": "Mol. Pharmacol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "48",
      "DOI": "10.1016/S0022-2836(66)80075-X",
      "article-title": "A further study of misreading of codons induced by streptomycin and neomycin using ribopolynucleotides containing two nucleotides in alternating sequence as templates",
      "volume": "18",
      "author": "Davies",
      "year": "1966",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "127",
      "DOI": "10.1016/0022-2836(90)90309-A",
      "article-title": "Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16 S ribosomal RNA",
      "volume": "212",
      "author": "DeStasio",
      "year": "1990",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "1367",
      "DOI": "10.1126/science.274.5291.1367",
      "article-title": "Structure of the A site of E. coli 16 S rRNA complexed with an aminoglycoside antibiotic",
      "volume": "274",
      "author": "Fourmy",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "333",
      "DOI": "10.1006/jmbi.1997.1551",
      "article-title": "Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA",
      "volume": "277",
      "author": "Fourmy",
      "year": "1998",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB9",
      "series-title": "The Molecular Basis of Antibiotic Action",
      "author": "Gale",
      "year": "1981"
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "87",
      "DOI": "10.1016/0014-5793(94)00740-3",
      "article-title": "A pulsed field gradient isotope-filtered 3D 13C HMQC-NOESY experiment for extracting intermolecular NOE contacts in molecular complexes",
      "volume": "350",
      "author": "Lee",
      "year": "1994",
      "journal-title": "FEBS Letters"
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB11",
      "series-title": "Nitrogen-15 Nuclear Magnetic Resonance Spectroscopy",
      "article-title": "Nitrogen-15 nuclear magnetic resonance spectroscopy",
      "author": "Levy",
      "year": "1979"
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "2205",
      "DOI": "10.1021/ja00084a095",
      "article-title": "Correlation of adenine H2/H8 resonances in uniformly 13C labeled RNAs by 2D HCCH-TOCSY",
      "volume": "116",
      "author": "Marino",
      "year": "1994",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "6472",
      "DOI": "10.1021/ja00093a073",
      "article-title": "A three-dimensional triple-resonance 1H, 13C, 31P experiment",
      "volume": "116",
      "author": "Marino",
      "year": "1994",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "985",
      "DOI": "10.1016/0092-8674(86)90813-5",
      "article-title": "Transfer RNA shields specific nucleotides in 16 S ribosomal RNA from attack by chemical probes",
      "volume": "47",
      "author": "Moazed",
      "year": "1986",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "389",
      "DOI": "10.1038/327389a0",
      "article-title": "Interaction of antibiotics with functional sites in 16 S ribosomal RNA",
      "volume": "327",
      "author": "Moazed",
      "year": "1987",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "135",
      "DOI": "10.1016/0022-2836(90)90016-F",
      "article-title": "Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA",
      "volume": "211",
      "author": "Moazed",
      "year": "1990",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "399",
      "DOI": "10.1016/0022-2836(86)90441-9",
      "article-title": "Rapid chemical probing of conformation in 16 S ribosomal RNA and 30 S ribosomal subunits using primer extension",
      "volume": "187",
      "author": "Moazed",
      "year": "1986",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "11043",
      "DOI": "10.1021/ja00150a001",
      "article-title": "Improved RNA structure determination by detection of NOE contacts to exchange-broadened amino protons",
      "volume": "117",
      "author": "Mueller",
      "year": "1995",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "39",
      "DOI": "10.1017/S0033583500005412",
      "article-title": "Heteronuclear filters in two-dimensional [1H-1H]-NMR spectroscopy",
      "volume": "23",
      "author": "Otting",
      "year": "1990",
      "journal-title": "Quart. Rev. Biophys."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "323",
      "DOI": "10.1016/S0076-6879(95)61016-2",
      "article-title": "Biochemical and NMR studies of RNA conformation with an emphasis on RNA pseudoknots",
      "volume": "261",
      "author": "Puglisi",
      "year": "1995",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "421",
      "DOI": "10.1006/jmbi.1996.0526",
      "article-title": "RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide",
      "volume": "262",
      "author": "Recht",
      "year": "1996",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB22",
      "first-page": "202",
      "article-title": "A constant-time 2D overbodenhausen experiment for inverse correlation of isotopically enriched species",
      "volume": "97",
      "author": "Santoro",
      "year": "1992",
      "journal-title": "J. Magn. Reson."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "94",
      "DOI": "10.1016/0014-5793(86)81539-3",
      "article-title": "Assignment of the 31P and 1H resonances in oligonucleotides by two-dimensional NMR spectroscopy",
      "volume": "208",
      "author": "Skl\u00e9nar",
      "year": "1986",
      "journal-title": "FEBS Letters"
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "4776",
      "DOI": "10.1021/ja00064a043",
      "article-title": "Solvent suppression with symmetrically-shifted pulses",
      "volume": "115",
      "author": "Smallcombe",
      "year": "1993",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "481",
      "DOI": "10.1016/S0076-6879(88)64064-X",
      "article-title": "Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension",
      "volume": "164",
      "author": "Stern",
      "year": "1988",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "9349",
      "DOI": "10.1021/ja00024a044",
      "article-title": "Carbon assignments and heteronuclear coupling constants for an RNA oligonucleotide form natural abundance 13C-1H correlated experiments",
      "volume": "113",
      "author": "Varani",
      "year": "1991",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "10.1006/jmbi.1997.1552_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "3099",
      "DOI": "10.1002/j.1460-2075.1991.tb07863.x",
      "article-title": "Interaction of antibiotics with A and P-site-specific bases in 16 S ribosomal RNA",
      "volume": "10",
      "author": "Woodcock",
      "year": "1991",
      "journal-title": "EMBO J."
    }
  ],
  "container-title": "Journal of Molecular Biology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0022283697915527?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0022283697915527?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        4,
        4
      ]
    ],
    "date-time": "2023-04-04T14:15:07Z",
    "timestamp": 1680617707000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0022283697915527"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1998,
        3
      ]
    ]
  },
  "references-count": 27,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1998,
          3
        ]
      ]
    }
  },
  "alternative-id": [
    "S0022283697915527"
  ],
  "URL": "http://dx.doi.org/10.1006/jmbi.1997.1552",
  "relation": {},
  "ISSN": [
    "0022-2836"
  ],
  "subject": [],
  "container-title-short": "Journal of Molecular Biology",
  "published": {
    "date-parts": [
      [
        1998,
        3
      ]
    ]
  }
}