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Experimental Neurology (78)
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Ankeny, D. P., McTigue, D. M., Guan, Z., Yan, Q., Kinstler, O., Stokes, B. T., & Jakeman, L. B. (2001). Pegylated Brain-Derived Neurotrophic Factor Shows Improved Distribution into the Spinal Cord and Stimulates Locomotor Activity and Morphological Changes after Injury. Experimental Neurology, 170(1), 85–100.

Authors 7
  1. Daniel P. Ankeny (first)
  2. Dana M. McTigue (additional)
  3. Zhen Guan (additional)
  4. Qiao Yan (additional)
  5. Olaf Kinstler (additional)
  6. Bradford T. Stokes (additional)
  7. Lyn B. Jakeman (additional)
References 78 Referenced 73
  1. 10.1006/exnr.1994.1182 / Exp. Neurol. / The neurotrophins NT-4/5 and BDNF augment serotonin, dopamine, and GABAergic systems during behaviorally effective infusions to the substantia nigra by Altar (1994)
  2. 10.1002/cne.903570209 / J. Comp. Neurol. / Differential distribution of exogenous BDNF, NGF, and NT-3 in the brain corresponds to the relative abundance and distribution of high-affinity and low-affinity neurotrophin receptors by Anderson (1995)
  3. 10.1111/j.1460-9568.1995.tb01132.x / Eur. J. Neurosci. / Truncated and catalytic isoforms of trkB are coexpressed in neurons of rat and mouse CNS by Armanini (1995)
  4. 10.1089/neu.1995.12.1 / J. Neurotrauma. / A sensitive and reliable locomotor rating scale for open field testing in rats by Basso (1995)
  5. 10.1038/jcbfm.1994.86 / J. Cereb. Blood Flow Metab. / Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus by Beck (1994)
  6. 10.1089/neu.1992.9.197 / J. Neurotrauma / Spinal cord injury produced by consistent mechanical displacement of the cord in rats: Behavioral and histologic analysis by Behrmann (1992)
  7. 10.1021/bc990001k / Bioconjug. Chem. / Synthesis and biological activity of polyethylene glycol-mouse nerve growth factor conjugate by Belcheva (1999)
  8. 10.1016/S0166-2236(00)01682-9 / Trends Neurosci. / BDNF and epilepsy: Too much of a good thing? by Binder (2001)
  9. 10.1046/j.1460-9568.1998.00307.x / Eur. J. Neurosci. / NT-3, but not BDNF, prevents atrophy and death of axotomized spinal cord projection neurons by Bradbury (1998)
  10. 10.1006/exnr.1997.6705 / Exp. Neurol. / Neurotrophic factors increase axonal growth after spinal cord injury and transplantation in the adult rat by Bregman (1997)
  11. 10.1006/exnr.1994.1197 / Exp. Neurol. / Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: Rescue by neurotrophins by Burke (1994)
  12. 10.1523/JNEUROSCI.15-07-04943.1995 / J. Neurosci. / Localization and organization of the central pattern generator for hindlimb locomotion in newborn rat by Cazalets (1995)
  13. 10.1126/science.273.5274.510 / Science / Spinal cord repair in adult paraplegic rats: Partial restoration of hind limb function by Cheng (1996)
  14. 10.1074/jbc.271.36.21969 / J. Biol. Chem. / Long-acting growth hormones produced by conjugation with polyethylene glycol by Clark (1996)
  15. 10.1006/exnr.1996.0157 / Exp. Neurol. / Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons by Dittrich (1996)
  16. {'key': '10.1006/exnr.2001.7699_RF16', 'first-page': '233', 'article-title': 'Use-dependent plasticity in spinal stepping and standing', 'volume': '72', 'author': 'Edgerton', 'year': '1997', 'journal-title': 'Adv. Neurol.'} / Adv. Neurol. / Use-dependent plasticity in spinal stepping and standing by Edgerton (1997)
  17. {'key': '10.1006/exnr.2001.7699_RF17', 'first-page': 'S119', 'article-title': 'Potential of adult mammalian lumbosacral spinal cord to execute and acquire improved locomotion in the absence of supraspinal input', 'volume': '9', 'author': 'Edgerton', 'year': '1992', 'journal-title': 'J. Neurotrauma'} / J. Neurotrauma / Potential of adult mammalian lumbosacral spinal cord to execute and acquire improved locomotion in the absence of supraspinal input by Edgerton (1992)
  18. 10.1152/jn.1998.80.6.3383 / J. Neurophysiol. / Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus by Frerking (1998)
  19. 10.1073/pnas.89.23.11282 / Proc. Natl. Acad. Sci. USA / Increased levels of trkB mRNA and trkB protein-like immunoreactivity in the injured rat and cat spinal cord by Frisen (1992)
  20. 10.1073/pnas.90.11.4971 / Proc. Natl. Acad. Sci. USA / Characterization of glial trkB receptors: Differential response to injury in the central and peripheral nervous systems by Frisen (1993)
  21. 10.1046/j.1471-4159.2000.740582.x / J. Neurochem. / Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway by Fryer (2000)
  22. 10.1146/annurev.ne.08.030185.001313 / Annu. Rev. Neurosci. / Central pattern generators for locomotion, with special reference to vertebrates by Grillner (1985)
  23. 10.1016/0031-9384(71)90221-6 / Physiol. Behav. / Facilitation by strychnine of reflex walking in spinal dogs by Hart (1971)
  24. 10.1016/0304-3940(89)90478-3 / Neurosci. Lett. / Nerve growth factor (NGF)-treated nitrocellulose enhances and directs the regeneration of adult rat dorsal root axons through intraspinal neural tissue transplants by Houle (1989)
  25. 10.1038/328632a0 / Nature / Induction of c-fos-like protein in spinal cord neurons following sensory stimulation by Hunt (1987)
  26. 10.1016/0165-3806(91)90013-9 / Dev. Brain Res. / l-dopa-induced air-stepping in decerebrate developing rats by Iwahara (1991)
  27. 10.1089/neu.2000.17.299 / J. Neurotrauma / Traumatic spinal cord injury produced by controlled contusion in mouse by Jakeman (2000)
  28. 10.1006/exnr.1998.6924 / Exp. Neurol. / Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury by Jakeman (1998)
  29. 10.1038/44847 / Nature / Neurotrophin-evoked rapid excitation through TrkB receptors by Kafitz (1999)
  30. 10.1126/science.7886457 / Science / Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus by Kang (1995)
  31. 10.1111/j.1749-6632.1998.tb09043.x / Ann. N.Y. Acad. Sci. / Distribution of central pattern generators for rhythmic motor outputs in the spinal cord of limbed vertebrates by Kiehn (1998)
  32. 10.1006/exnr.2000.7480 / Exp. Neurol. / Changes in truncated trkB and p75 receptor expression in the rat spinal cord following spinal cord hemisection and spinal cord hemisection plus neurotrophin treatment by King (2000)
  33. 10.1016/S0306-4522(99)00072-X / Neuroscience / trkA, trkB, and trkC messenger RNA expression by bulbospinal cells of the rat by King (1999)
  34. Kinstler, O. B, and, Yan, Q, 1994, BDNF and NT-3 polypeptides selectively linked to polyethylene glycol. Amgen, Inc. Thousand Oaks. U.S. Patent 340131(5770577). 6-23-1998. California, USA.
  35. 10.1006/exnr.1996.6367 / Exp. Neurol. / BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth by Kishino (1997)
  36. 10.1016/0092-8674(90)90476-U / Cell / The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain by Klein (1990)
  37. 10.1523/JNEUROSCI.17-24-09583.1997 / J. Neurosci. / BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-Tubulin mRNA expression, and promote axonal regeneration by Kobayashi (1997)
  38. 10.1126/science.7725105 / Science / Potentiated necrosis of cultured cortical neurons by neurotrophins by Koh (1995)
  39. 10.1097/00001756-199412300-00007 / NeuroReport / BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurons by Leßmann (1994)
  40. 10.1073/pnas.92.17.8074 / Proc. Natl. Acad. Sci. USA / Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors by Levine (1995)
  41. 10.1146/annurev.ne.19.030196.001445 / Annu. Rev. Neurosci. / Physiology of the neurotrophins by Lewin (1996)
  42. 10.1006/exnr.2000.7548 / Exp. Neurol. / Regulation of Trk receptors following contusion of the rat spinal cord by Liebl (2001)
  43. 10.1523/JNEUROSCI.08-07-02394.1988 / J. Neurosci. / Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons by Lindsay (1988)
  44. 10.1016/0166-2236(94)90099-X / Trends Neurosci. / Neurotrophic factors: From molecule to man by Lindsay (1994)
  45. 10.1523/JNEUROSCI.19-11-04370.1999 / J. Neurosci. / Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function by Liu (1999)
  46. 10.1038/363350a0 / Nature / Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF by Lohof (1993)
  47. 10.1523/JNEUROSCI.15-12-07929.1995 / J. Neurosci. / Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain by Mamounas (1995)
  48. 10.1089/neu.1994.11.3 / J. Neurotrauma / Endogenous neuroprotection factors and traumatic brain injury: mechanisms of action and implications for therapy by Mattson (1994)
  49. 10.1006/exnr.1997.6698 / Exp. Neurol. / Expression of full-length trkB receptors by reactive astrocytes after chronic CNS injury by McKeon (1997)
  50. 10.1523/JNEUROSCI.18-14-05354.1998 / J. Neurosci. / Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord by McTigue (1998)
  51. 10.1046/j.1460-9568.1998.00071.x / Eur. J. Neurosci. / Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord by Menei (1998)
  52. 10.1152/jn.1998.79.1.496 / J. Neurophysiol. / Acute intrahippocampal infusion of Brain-derived neurotrophic factor induces lasting potentiation of synaptic transmission in the rat dentate gyrus by Messaoudi (1998)
  53. 10.1016/0166-2236(89)90096-9 / Trends Neurosci. / Stimulus-transcription coupling in neurons: Role of cellular immediate-early genes by Morgan (1989)
  54. 10.1146/annurev.ne.14.030191.002225 / Annu. Rev. Neurosci. / Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes fos and jun by Morgan (1991)
  55. 10.1523/JNEUROSCI.13-10-04146.1993 / J. Neurosci. / Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection by Morse (1993)
  56. 10.1016/S0166-2236(96)10068-0 / Trends Neurosci. / Sensorimotor stimulation to improve locomotor recovery after spinal cord injury by Muir (1997)
  57. 10.1016/S0306-4522(96)00665-3 / Neuroscience / Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo by Novikov (1997)
  58. 10.1002/ana.410270115 / Ann. Neurol. / Alteration in extracellular amino acids after traumatic spinal cord injury by Panter (1990)
  59. 10.1023/A:1018940732550 / Pharmaceut. Res. / Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood–brain barrier in vivo using vector-mediated peptide drug delivery by Pardridge (1994)
  60. 10.1023/A:1011981927620 / Pharmaceut. Res. / Combined use of carboxyl-directed protein pegylation and vector-mediated blood-brain barrier drug delivery system optimizes brain uptake of brain-derived neurotrophic factor following intravenous administration by Pardridge (1998)
  61. 10.1006/exnr.1999.7118 / Exp. Neurol. / Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury by Popovich (1999)
  62. 10.1097/00019052-199812000-00007 / Curr. Opin. Neurol. / Biological interventions for spinal cord injury by Ribotta (1998)
  63. 10.1111/j.1471-4159.1986.tb13015.x / J. Neurochem. / Receptor binding activities of biotinylated derivatives of β-nerve growth factor by Rosenberg (1986)
  64. {'key': '10.1006/exnr.2001.7699_RF64', 'first-page': '273', 'article-title': 'Early response genes as markers of neuronal activity and growth factor action', 'volume': '59', 'author': 'Sagar', 'year': '1993', 'journal-title': 'Adv. Neurol.'} / Adv. Neurol. / Early response genes as markers of neuronal activity and growth factor action by Sagar (1993)
  65. 10.1023/A:1012117815460 / Pharmaceut. Res. / Carboxyl-directed pegylation of brain-derived neurotrophic factor markedly reduces systemic clearance with minimal loss of biologic activity by Sakane (1997)
  66. 10.1152/physrev.1996.76.2.319 / Physiol. Rev. / Degeneration and regeneration of axons in the lesioned spinal cord by Schwab (1996)
  67. 10.1002/eji.1830220316 / Eur. J. Immunol. / Suppression and transient induction of lymphokines in cancer patients after administration of polyethylene glycolated interleukin-2 by Shih (1992)
  68. 10.1016/0006-8993(95)01289-3 / Brain Res. / BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration by Siuciak (1996)
  69. 10.1089/neu.1992.9.187 / J. Neurotrauma / An electromechanical spinal injury device with dynamic sensitivity by Stokes (1992)
  70. 10.1523/JNEUROSCI.16-10-03256.1996 / J. Neurosci. / Synaptic modulation by neurotrophic factors: Differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor by Stoop (1996)
  71. 10.1016/S0079-6123(08)61142-5 / Prog. Brain Res. / Response of rubrospinal and corticospinal neurons to injury and neurotrophins by Tetzlaff (1994)
  72. 10.1126/science.270.5236.593 / Science / Neurotrophins and neuronal plasticity by Thoenen (1995)
  73. 10.1111/j.1349-7006.1994.tb02879.x / Jpn. J. Cancer Res. / Chemical modification of natural human tumor necrosis factor-alpha with polyethylene glycol increases its anti-tumor potency by Tsutsumi (1994)
  74. 10.1016/0165-3806(91)90012-8 / Dev. Brain Res. / l-dopa-induced air-stepping in developing rats by Van Hartesveldt (1991)
  75. 10.1073/pnas.96.1.254 / Proc. Natl. Acad. Sci. USA / Neuroprotection with noninvasive neurotrophin delivery to the brain by Wu (1999)
  76. 10.1006/exnr.1994.1076 / Exp. Neurol. / Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression by Yan (1994)
  77. 10.1006/exnr.1996.6353 / Exp. Neurol. / Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons by Ye (1997)
  78. {'key': '10.1006/exnr.2001.7699_RF78', 'series-title': 'PEG Chemistry: Biotechnical and Biomedical Applications', 'first-page': '347', 'author': 'Zalipsky', 'year': '1992'} / PEG Chemistry: Biotechnical and Biomedical Applications by Zalipsky (1992)
Dates
Type When
Created 22 years, 11 months ago (Sept. 16, 2002, 11:46 a.m.)
Deposited 5 years, 8 months ago (Dec. 16, 2019, 11:32 p.m.)
Indexed 1 year ago (July 29, 2024, 5:56 p.m.)
Issued 24 years, 1 month ago (July 1, 2001)
Published 24 years, 1 month ago (July 1, 2001)
Published Print 24 years, 1 month ago (July 1, 2001)
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@article{Ankeny_2001, title={Pegylated Brain-Derived Neurotrophic Factor Shows Improved Distribution into the Spinal Cord and Stimulates Locomotor Activity and Morphological Changes after Injury}, volume={170}, ISSN={0014-4886}, url={http://dx.doi.org/10.1006/exnr.2001.7699}, DOI={10.1006/exnr.2001.7699}, number={1}, journal={Experimental Neurology}, publisher={Elsevier BV}, author={Ankeny, Daniel P. and McTigue, Dana M. and Guan, Zhen and Yan, Qiao and Kinstler, Olaf and Stokes, Bradford T. and Jakeman, Lyn B.}, year={2001}, month=jul, pages={85–100} }