Crossref journal-article
Elsevier BV
Developmental Biology (78)
Bibliography

Liberatore, C. M., Searcy-Schrick, R. D., Vincent, E. B., & Yutzey, K. E. (2002). Nkx-2.5 Gene Induction in Mice Is Mediated by a Smad Consensus Regulatory Region. Developmental Biology, 244(2), 243–256.

Authors 4
  1. Christine M. Liberatore (first)
  2. Robin D. Searcy-Schrick (additional)
  3. Eric B. Vincent (additional)
  4. Katherine E. Yutzey (additional)
References 64 Referenced 73
  1. 10.1016/S0925-4773(97)00186-X / Mech. Dev. / BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos by Andree (1998)
  2. 10.1016/S0955-0674(99)00081-2 / Curr. Opin. Cell Biol. / Smads as transcriptional co-modulators by Attisano (2000)
  3. 10.1006/dbio.2000.9817 / Dev. Biol. / Staging of the commitment of murine cardiac cell progenitors by Auda-Boucher (2000)
  4. 10.1101/gad.7.7b.1325 / Genes Dev. / tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila by Azpiazu (1993)
  5. 10.1083/jcb.95.3.763 / J. Cell Biol. / Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro by Bader (1982)
  6. 10.1172/JCI8154 / J. Clin. Invest. / Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways by Benson (1999)
  7. 10.1242/dev.118.3.719 / Development / The gene tinman is required for specification of the heart and visceral muscles in Drosophila by Bodmer (1993)
  8. 10.1242/dev.126.8.1631 / Development / Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects by Chang (1999)
  9. 10.1002/(SICI)1097-4652(200006)183:3<381::AID-JCP11>3.0.CO;2-O / J. Cell Physiol. / Interaction of Smad3 with a proximal Smad-binding element of the human alpha2(I) procollagen gene promoter required for transcriptional activation by TGF-beta by Chen (2000)
  10. 10.1101/gad.12.14.2144 / Genes Dev. / Determinants of specificity in TGF-beta signal transduction by Chen (1998)
  11. 10.1161/01.RES.78.5.790 / Circ. Res. / Endogenous retinoic acid signaling colocalizes with advanced expression of the adult smooth muscle myosin heavy chain isoform during development of the ductus arteriosus by Colbert (1996)
  12. 10.1093/emboj/17.11.3091 / EMBO J. / Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene by Dennler (1998)
  13. 10.1242/dev.118.4.1255 / Development / Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope by Downs (1993)
  14. 10.1006/dbio.1998.9167 / Dev. Biol. / Lack of regulation in the heart forming region of avian embryos by Ehrman (1999)
  15. 10.1038/374464a0 / Nature / Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo by Frasch (1995)
  16. 10.1006/dbio.1996.0212 / Dev. Biol. / NK-2 homeobox genes and heart development by Harvey (1996)
  17. 10.1101/gad.12.2.186 / Genes Dev. / Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor by Hata (1998)
  18. 10.1074/jbc.275.9.6075 / J. Biol. Chem. / Smad6 is a Smad1/5-induced Smad inhibitor by Ishida (2000)
  19. 10.1074/jbc.274.29.20709 / J. Biol. Chem. / Interaction of Smad complexes with tripartite DNA-binding sites by Johnson (1999)
  20. 10.1161/01.RES.88.1.30 / Circ. Res. / Transforming growth factor-β/Smads. signaling induces transcription of the cell type-restricted ankyrin repeat protein CARP gene through CAGA motif in vascular smooth muscle cells by Kanai (2001)
  21. 10.1016/S1359-6101(97)00036-1 / Cytokine Growth Factor Rev. / Signal transduction by bone morphogenetic proteins by Kawabata (1998)
  22. 10.1038/40906 / Nature / Drosophila Mad binds to DNA a directly mediates activation of vestigial by Decapentaplegic by Kim (1997)
  23. 10.1006/dbio.2001.0397 / Dev. Biol. / Molecular integration of inductive and mesoderm-intrinsic inputs governs even-skipped enhancer activity in a subset of pericardial and dorsal muscle progenitors by Knirr (2001)
  24. 10.1073/pnas.90.17.8145 / Proc. Natl. Acad. Sci. USA / Csx: a murine homeobox-containing gene specifically expressed in the developing heart by Komuro (1993)
  25. 10.1016/S1097-2765(00)80119-7 / Mol. Cell / Smad2 and Smad3 positively and negatively regulate TGFβ-dependent transcription through the forkhead DNA binding protein FAST2 by Labbe (1998)
  26. 10.1242/dev.126.1.75 / Development / Control of early cardiac-specific transcription of Nkx2–5 by a GATA- dependent enhancer by Lien (1999)
  27. 10.1006/dbio.2002.0603 / Dev. Biol. / Cardiac-specific activity of an Nkx2.5 enhancer requires an evolutionarily conserved binding site by Lien (2002)
  28. 10.1242/dev.119.2.419 / Development / Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants by Lints (1993)
  29. 10.1002/(SICI)1097-0177(200004)217:4<327::AID-DVDY1>3.0.CO;2-K / Dev. Dyn. / Endoderm and heart development by Lough (2000)
  30. 10.1101/gad.9.13.1654 / Genes Dev. / Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeobox gene Nkx2–5 by Lyons (1995)
  31. 10.1101/gad.14.6.627 / Genes Dev. / Controlling TGF-β signaling by Massague (2000)
  32. 10.1016/0014-4827(91)90404-I / Exp. Cell Res. / In vivo analysis of a new lacZ retrovirus vector suitable for cell lineage marking in avian and other species by Mikawa (1991)
  33. 10.1128/MCB.19.10.7096 / Mol. Cell. Biol. / Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4 by Monzen (1999)
  34. 10.1083/jcb.153.4.687 / J. Cell Biol. / Smads, TAK1,. and their common target ATF-2 play a critical role in cardiomyocyte differentiation by Monzen (2001)
  35. 10.1006/dbio.1998.9081 / Dev. Biol. / Drosophila mef2 expression during mesoderm development is controlled by a complex array of cis-acting regulatory modules by Nguyen (1998)
  36. 10.1242/dev.126.4.839 / Development / Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2–5 by Reecy (1999)
  37. 10.1016/S0925-4773(99)00311-1 / Mech. Dev. / BMP2 is required for early heart development during a distinct time period by Schlange (2000)
  38. 10.1126/science.281.5373.108 / Science / Congenital heart disease caused by mutations in the transcription factor NKX2–5 by Schott (1998)
  39. 10.1242/dev.121.12.4203 / Development / Induction of avian cardiac myogenesis by anterior endoderm by Schultheiss (1995)
  40. 10.1101/gad.11.4.451 / Genes Dev. / A role for bone morphogenetic proteins in the induction of cardiac myogenesis by Schultheiss (1997)
  41. 10.1242/dev.126.19.4187 / Development / Building the heart piece by piece: Modularity of cis-elements regulating Nkx2–5 transcription by Schwartz (1999)
  42. 10.1242/dev.125.22.4461 / Development / A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice by Searcy (1998)
  43. 10.1006/dbio.2000.9802 / Dev. Biol. / BMP signaling is required for heart formation in vertebrates by Shi (2000)
  44. 10.1038/45439 / Nature / BMP signalling specifies the pyloric sphincter by Smith (1999)
  45. 10.1242/dev.127.17.3671 / Development / Roles of BMP signaling and Nkx2.5 in patterning at the chick midgut–foregut boundary by Smith (2000)
  46. 10.1006/dbio.2000.9891 / Dev. Biol. / Regulation of the tinman homologues in Xenopus embryos by Sparrow (2000)
  47. 10.1074/jbc.274.14.9431 / J. Biol. Chem. / Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor β-induced Smad-dependent transcriptional activation by Stroschein (1999)
  48. 10.1242/dev.126.7.1439 / Development / Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5 by Tanaka (1999)
  49. 10.1074/jbc.275.22.16709 / J. Biol. Chem. / Induction of platelet-derived growth factor B-chain expression involves transactivation by Smads by Taylor (2000)
  50. 10.1007/BF03402205 / Mol. Med. / Molecular cloning, chromosomal mapping and characterization of the human cardiac-specific homeobox gene hCsx by Turbay (1996)
  51. 10.1242/dev.128.16.3179 / Development / Conotruncal myocardium arises from a secondary heart field by Waldo (2001)
  52. 10.1101/gad.12.16.2445 / Genes Dev. / Smads and early developmental signaling by the Tgfβ superfamily by Whitman (1998)
  53. {'key': '10.1006/dbio.2002.0604_RF53', 'series-title': 'Essential Developmental Biology', 'first-page': '257', 'article-title': 'In situ hybridization', 'author': 'Wilkinson', 'year': '1993'} / Essential Developmental Biology / In situ hybridization by Wilkinson (1993)
  54. 10.1128/MCB.19.3.1821 / Mol. Cell. Biol. / Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor β by Wong (1999)
  55. 10.1016/S0092-8674(00)80712-6 / Cell / A Smad transcriptional corepressor by Wotton (1999)
  56. 10.1016/S0092-8674(00)81556-1 / Cell / Regulation of Smad activity by Wrana (2000)
  57. 10.1101/gad.12.15.2354 / Genes Dev. / Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm by Xu (1998)
  58. 10.1006/dbio.1999.9419 / Dev. Biol. / Evidence for a role of Smad6 in chick cardiac development by Yamada (1999)
  59. 10.1073/pnas.93.17.8940 / Proc. Natl. Acad. Sci. USA / Mammalian dwarfins are phosphorylated in response to transforming growth factor β and are implicated in control of cell growth by Yingling (1996)
  60. 10.1006/dbio.1995.1234 / Dev. Biol. / Diversification of cardiomyogenic cell lineages in vitro by Yutzey (1995)
  61. 10.1002/dvdy.10068 / Dev. Dyn. / Wherefore heart thou? Embryonic origins of cardiogenic mesoderm by Yutzey (2002)
  62. 10.1016/S1097-2765(00)80061-1 / Mol. Cell / Human Smad3 and Smad4 are sequence-specific transcription activators by Zawal (1998)
  63. 10.1242/dev.122.10.2977 / Development / Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development by Zhang (1996)
  64. 10.1074/jbc.M003339200 / J. Biol. Chem. / Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor β1 stimulation of α2(I)-collagen (COL1A2) transcription by Zhang (2000)
Dates
Type When
Created 22 years, 11 months ago (Sept. 16, 2002, 11:45 a.m.)
Deposited 2 years, 4 months ago (April 4, 2023, 2:26 a.m.)
Indexed 4 months, 2 weeks ago (April 19, 2025, 2:45 a.m.)
Issued 23 years, 5 months ago (April 1, 2002)
Published 23 years, 5 months ago (April 1, 2002)
Published Print 23 years, 5 months ago (April 1, 2002)
Funders 0

None

@article{Liberatore_2002, title={Nkx-2.5 Gene Induction in Mice Is Mediated by a Smad Consensus Regulatory Region}, volume={244}, ISSN={0012-1606}, url={http://dx.doi.org/10.1006/dbio.2002.0604}, DOI={10.1006/dbio.2002.0604}, number={2}, journal={Developmental Biology}, publisher={Elsevier BV}, author={Liberatore, Christine M. and Searcy-Schrick, Robin D. and Vincent, Eric B. and Yutzey, Katherine E.}, year={2002}, month=apr, pages={243–256} }