DOI: 10.1006/dbio.2000.9960. Notch Signaling: From the Outside In

Notch Signaling: From the Outside In

10.1006/dbio.2000.9960

Crossref journal-article

Elsevier BV

Developmental Biology (78)

Bibliography

Mumm, J. S., & Kopan, R. (2000). Notch Signaling: From the Outside In. Developmental Biology, 228(2), 151â165.

Authors 2

Jeffrey S. Mumm (first)
Raphael Kopan (additional)

References 178 Referenced 784

10.1016/0925-4773(95)00425-4 / Mech. Dev. / Involvement of Notch-1 in mammalian retinal neurogenesis—Association of Notch-1 activity with both immature and terminally differentiated cells by Ahmad (1995)
10.1074/jbc.274.49.35269 / J. Biol. Chem. / c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads by Akiyoshi (1999)
10.1006/scdb.1999.0292 / Semin. Cell Dev. Biol. / Regulative development of the sea urchin embryo: Signalling cascades and morphogen gradients [Review] by Angerer (1999)
10.1016/S0166-2236(99)01455-1 / Trends Neurosci. / Presenilins: Molecular switches between proteolysis and signal transduction [Review] by Annaert (1999)
{'key': '10.1006/dbio.2000.9960_RF5', 'first-page': '325', 'article-title': 'Interactions between Wingless and Notch during the assignation of cell fates in Drosophila', 'volume': '42', 'author': 'Arias', 'year': '1998', 'journal-title': 'Int. J. Dev. Biol.'} / Int. J. Dev. Biol. / Interactions between Wingless and Notch during the assignation of cell fates in Drosophila by Arias (1998)
10.1126/science.284.5415.770 / Science / Notch signaling: Cell fate control and signal integration in development [Review] by Artavanis-Tsakonas (1999)
10.1101/SQB.1994.059.01.016 / Cold Spring Harbor Symp. Quant. Biol. / Functional analysis of the TAN-1 gene, a human homolog of Drosophila Notch by Aster (1994)
10.1074/jbc.272.17.11336 / J. Biol. Chem. / Oncogenic forms of Notch1 lacking either the primary binding site for RBP-j-kappa or nuclear localization sequences retain the ability to associate with RBP-j-kappa and activate transcription by Aster (1997)
10.1126/science.271.5257.1826 / Science / Interaction between Wingless and Notch signaling pathways mediated by dishevelled by Axelrod (1996)
10.1002/(SICI)1521-1878(200003)22:3<264::AID-BIES8>3.0.CO;2-M / Bioessays / Notch signaling in the nervous system. Pieces still missing from the puzzle by Baker (2000)
10.1074/jbc.273.26.16434 / J. Biol. Chem. / Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription by Baudino (1998)
10.1002/(SICI)1097-4547(19981015)54:2<125::AID-JNR1>3.0.CO;2-G / J. Neurosci. Res. / Notch and neurogenesis [Review] by Beatus (1998)
10.1111/j.1600-065X.2000.imr017513.x / Immunol. Rev. / Microenvironmental influences on human B-cell development [Review] by Bertrand (2000)
10.1016/S0092-8674(00)81180-0 / Cell / A Notch affair [Review] by Bray (1998)
10.1006/scdb.1998.0262 / Semin. Cell Dev. Biol. / Notch signalling in Drosophila: Three ways to use a pathway [Review] by Bray (1998)
10.1016/S0960-9822(99)80313-3 / Curr. Biol. / Repression by Notch is required before Wingless signalling during muscle progenitor cell development in Drosophila by Brennan (1999)
10.1006/dbio.1999.9502 / Dev. Biol. / Wingless modulates the effects of dominant negative Notch molecules in the developing wing of Drosophila by Brennan (1999)
10.1093/genetics/147.1.177 / Genetics / A functional analysis of Notch mutations in Drosophila by Brennan (1997)
10.1006/dbio.1999.9501 / Dev. Biol. / The Abruptex mutations of Notch disrupt the establishment of proneural clusters in Drosophila by Brennan (1999)
10.1016/S1097-2765(00)80417-7 / Mol. Cell / A novel proteolytic cleavage involved in Notch signaling: The role of the distinigrin-metalloprotease TACE by Brou (2000)
10.1016/S0092-8674(00)80213-5 / Cell / The SREBP pathway—Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor [Review] by Brown (1997)
10.1016/S0092-8674(00)80675-3 / Cell / Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans by Brown (2000)
10.1038/35019075 / Nature / Glycosyltransferase activity of Fringe modulates Notch-Delta interactions by Bruckner (2000)
10.1016/S0896-6273(00)80274-3 / Neuron / Numb diverts Notch pathway off the tramtrack [Review] by Campos-Ortega (1996)
10.1016/S0092-8674(00)81583-4 / Cell / Roles for proteolysis and trafficking in Notch maturation and signal transduction [Review] by Chan (1998)
10.1016/S0896-6273(00)80771-0 / Neuron / Presenilins, processing of beta-amyloid precursor protein, and Notch signaling [Review] by Chan (1999)
10.1016/0092-8674(93)90247-N / Cell / Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos by Coffman (1993)
10.1242/dev.121.5.1533 / Development / Notch1 is required for the coordinate segmentation of somites by Conlon (1995)
10.1093/genetics/152.2.567 / Genetics / The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase by Cornell (1999)
10.1038/sj.onc.1201687 / Oncogene / The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42 by Dahl (1998)
10.1083/jcb.127.4.915 / J. Cell Biol. / Induction of mutant dynamin specifically blocks endocytic coated vesicle formation by Damke (1994)
10.1038/19083 / Nature / A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain by De Strooper (1999)
10.1038/34910 / Nature / Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein by De Strooper (1998)
10.1016/S0952-7915(99)00067-9 / Curr. Opin. Immunol. / Notch signaling in T cell development [Review] by Deftos (2000)
10.1101/gad.13.8.954 / Genes Dev. / ebi regulates epidermal growth factor receptor signaling pathways in Drosophila by Dong (1999)
10.1101/gad.13.21.2801 / Genes Dev. / Mice lacking both presenilin genes exhibit early embryonic patterning defects by Donoviel (1999)
10.1128/MCB.14.5.3310 / Mol. Cell. Biol. / The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor by Dou (1994)
10.1073/pnas.97.14.7877 / Proc. Natl. Acad. Sci. USA / SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans by Doyle (2000)
10.1016/0092-8674(91)90111-B / Cell / TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms by Ellisen (1991)
10.1038/35017062 / Nature Cell Biol. / Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1 by Esler (2000)
10.1016/0092-8674(94)90196-1 / Cell / The suppressor of hairless protein participates in Notch receptor signaling by Fortini (1994)
10.1038/365555a0 / Nature / An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye by Fortini (1993)
10.1093/genetics/150.4.1477 / Genetics / Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of Notch signaling by Fostier (1998)
10.1016/S0896-6273(00)81171-X / Neuron / rax, hes1, and Notch1 promote the formation of Muller glia by postnatal retinal progenitor cells by Furukawa (2000)
10.1016/S0896-6273(00)81172-1 / Neuron / Radial glial identity is promoted by Notch1 signaling in the murine forebrain by Gaiano (2000)
10.1002/(SICI)1096-9926(199910)60:4<226::AID-TERA7>3.0.CO;2-W / Teratology / 1998 Warkany Lecture: Signaling pathways in development by Gerhart (1999)
10.1242/dev.127.11.2481 / Development / aph-2 encodes a novel extracellular protein required for GLP-1-mediated signaling by Goutte (2000)
10.1016/0959-437X(94)90072-B / Curr. Opin. Genet. Dev. / Structure/function studies of lin-12/Notch proteins [Review] by Greenwald (1994)
10.1101/gad.12.12.1751 / Genes Dev. / Lin-12/Notch signaling—Lessons from worms and flies [Review] by Greenwald (1998)
10.1016/0092-8674(92)90470-W / Cell / Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells by Greenwald (1992)
10.1006/mcne.1997.0610 / Mol. Cell. Neurosci. / Notch signaling in vertebrate development and disease [Review] by Gridley (1997)
10.1007/BF00267238 / Mol. Gen. Genet. / Temperature-sensitive mutations in Drosophila melanogaster. XIV. A selection of immobile adults by Grigliatti (1973)
10.1016/S0925-4773(98)00071-9 / Mech. Dev. / Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb by Hammond (1998)
10.1182/blood.V95.5.1616.005k31_1616_1625 / Blood / A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells by Han (2000)
10.1038/18979 / Nature / Alzheimer's disease—In search of gamma-secretase by Hardy (1999)
10.1006/dbio.1999.9477 / Dev. Biol. / Engineered truncations in the Drosophila mastermind protein disrupt Notch pathway function by Helms (1999)
10.1073/pnas.96.21.11872 / Proc. Natl. Acad. Sci. USA / Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency by Herreman (1999)
10.1083/jcb.122.3.565 / J. Cell Biol. / Effects of mutant rat dynamin on endocytosis by Herskovits (1993)
10.1046/j.1365-2567.2000.00073.x / Immunology / T-cell regulation of peripheral tolerance and immunity: The potential role for Notch signalling [Review] by Hoyne (2000)
10.1073/pnas.96.1.23 / Proc. Natl. Acad. Sci. USA / CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex by Hsieh (1999)
10.1126/science.7725102 / Science / Masking of the CBF1/RBPjκ transcriptional repression domain by Epstein-Barr virus EBNA2 by Hsieh (1995)
10.1101/gad.11.23.3182 / Genes Dev. / Sel-10 a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the cdc4 family of proteins by Hubbard (1997)
10.1093/genetics/145.2.359 / Genetics / Beaded of goldschmidt, an antimorphic allele of serrate, encodes a protein lacking transmembrane and intracellular domains by Hukriede (1997)
10.1038/35016111 / Nature / Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1 by Huppert (2000)
10.1038/377355a0 / Nature / Signalling downstream of activated mammalian Notch by Jarriault (1995)
10.1101/gad.6.3.345 / Genes Dev. / Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands by Jhappan (1992)
10.1006/scdb.1998.0261 / Semin. Cell Dev. Biol. / Notch signalling pathway and human diseases [Review] by Joutel (1998)
10.1038/35012090 / Nature / Fringe forms a complex with Notch by Ju (2000)
10.1101/gad.12.15.2269 / Genes Dev. / A histone deacetylase corepressor complex regulates the Notch signal transduction pathway by Kao (1998)
10.1242/dev.124.20.4133 / Development / Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives by Kato (1997)
10.1101/gad.12.23.3728 / Genes Dev. / Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos by Kidd (1998)
10.1016/S0968-0004(98)01263-8 / Trends Biochem. Sci. / Notch/Lin-12 signaling—Transduction by regulated protein slicing by Kimble (1998)
10.1146/annurev.cellbio.13.1.333 / Ann. Rev. Cell Dev. Biol. / The Lin-12/Notch signaling pathway and its regulation [Review] by Kimble (1997)
{'key': '10.1006/dbio.2000.9960_RF74', 'article-title': 'Good things must come to an end: How is Notch signaling turned off?', 'author': 'Kopan', 'year': '1999', 'journal-title': 'Perspective, STKE'} / Perspective, STKE / Good things must come to an end: How is Notch signaling turned off? by Kopan (1999)
10.1101/gad.836900 / Genes Dev. / A common enzyme connects Notch signaling with Alzheimer disease by Kopan (2000)
10.1242/dev.120.9.2385 / Development / The intracellular domain of mouse Notch: A constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD by Kopan (1994)
10.1073/pnas.93.4.1683 / Proc. Natl. Acad. Sci. USA / Signal transduction by activated mNotch: Importance of proteolytic processing and its regulation by the extracellular domain by Kopan (1996)
10.1016/S0959-4388(96)80090-0 / Curr. Opin. Neurobiol. / The Notch pathway: Democracy and aristocracy in the selection of cell fate by Kopan (1996)
10.1083/jcb.97.2.499 / J. Cell Biol. / Reversible blockage of membrane retrieval and endocytosis in the garland cell of the temperature-sensitive mutant of Drosophila melanogaster, shibirets1 by Kosaka (1983)
10.1073/pnas.040556497 / Proc. Natl. Acad. Sci. USA / Notch signaling and the determination of appendage identity by Kurata (2000)
10.1074/jbc.274.11.7238 / J. Biol. Chem. / Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis by Kuroda (1999)
10.1074/jbc.M000909200 / J. Biol. Chem. / Functional interaction between the mouse Notch1 intracellular region and histone acetyltransferases PCAF and GCN5 by Kurooka (2000)
10.1093/nar/26.23.5448 / Nucleic Acids Res. / Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region by Kurooka (1998)
10.1101/gad.9.21.2598 / Genes Dev. / The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling by Lecourtois (1995)
10.1016/S0960-9822(98)70300-8 / Curr. Biol. / Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos by Lecourtois (1998)
10.1038/377351a0 / Nature / Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans s182 Alzheimers disease gene by Levitan (1995)
10.1242/dev.125.18.3599 / Development / Effects of SEL-12 presenilin on LIN-12 localization and function in Caenorhabditis elegans by Levitan (1998)
10.1006/scdb.1998.0266 / Semin. Cell Dev. Biol. / Notch signalling and the control of cell fate choices in vertebrates [Review] by Lewis (1998)
10.1016/S1074-7613(00)80457-4 / Immunity / The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32d cells through interaction with Notch1 by Li (1998)
10.1073/pnas.94.22.12204 / Proc. Natl. Acad. Sci. USA / HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling by Li (1997)
10.1038/35015085 / Nature / Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1 by Li (2000)
10.1073/pnas.110126897 / Proc. Natl. Acad. Sci. USA / Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state by Li (2000)
10.1101/gad.7.10.1949 / Genes Dev. / Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei by Lieber (1993)
10.1242/dev.125.15.2893 / Development / A subset of Notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex by Ligoxygakis (1998)
10.1101/gad.13.17.2196 / Genes Dev. / The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling by Luo (1999)
10.1002/(SICI)1097-4652(199912)181:3<393::AID-JCP3>3.0.CO;2-6 / J. Cell. Physiol. / Arbiter of differentiation and death: Notch signaling meets apoptosis [Review] by Miele (1999)
10.1038/35019000 / Nature / Fringe is a glycosyltransferase that modifies Notch by Moloney (2000)
10.1101/gad.14.3.377 / Genes Dev. / Repression by Suppressor of Hairless and activation by Notch are required to define a single row of single-minde expressing cells in the Drosophila embryo by Morel (2000)
10.1016/S0092-8674(00)80860-0 / Cell / Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells by Morrison (2000)
10.1016/S1097-2765(00)80416-5 / Mol. Cell / A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1 by Mumm (2000)
10.1006/dbio.1994.1326 / Dev. Biol. / Delta-Notch signaling and Drosophila cell fate choice [Review] by Muskavitch (1994)
10.1006/dbio.1999.9324 / Dev. Biol. / Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators by Nellesen (1999)
10.1101/gad.13.4.412 / Genes Dev. / Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor by Nomura (1999)
10.1242/dev.120.9.2421 / Development / An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells by Nye (1994)
10.1101/gad.12.11.1621 / Genes Dev. / The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription by Olave (1998)
10.1128/MCB.18.4.2230 / Mol. Cell. Biol. / Notch inhibition of E47 supports the existence of a novel signaling pathway by Ordentlich (1998)
10.1006/scdb.1998.0263 / Semin. Cell Dev. Biol. / Modulators of Notch signaling [Review] by Panin (1998)
10.1242/dev.127.7.1373 / Development / Ligand endocytosis drives receptor dissociation and activation in the Notch pathway by Parks (2000)
10.1084/jem.183.5.2283 / J. Exp. Med. / Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles by Pear (1996)
10.1007/PL00000685 / Cell. Mol. Life Sci. / Determination of vertebrate retinal progenitor cell fate by the Notch pathway and basic helix-loop-helix transcription factors [Review] by Perron (2000)
10.1038/35012645 / Nature / LAG-3 a putative transcriptional activator in the C. elegans Notch pathway by Petcherski (2000)
10.1016/S0960-9822(00)00577-7 / Curr. Biol. / Mastermind is a putative activator for Notch by Petcherski (2000)
10.1016/0012-1606(90)90212-2 / Dev. Biol. / shibire, a neurogenic mutant of Drosophila by Poodry (1990)
10.1073/pnas.23.3.133 / Proc. Natl. Acad. Sci. USA / Chromosomal deficiencies and embryonic development of Drosophila melanogaster by Poulson (1937)
10.1126/science.283.5398.91 / Science / Processing of the Notch ligand Delta by the metalloprotease Kuzbanian by Qi (1999)
10.1074/jbc.M007300200 / J. Biol. Chem. / Recognition and ubiquitination of Notch by Itch, a Hect-Type E3 Ubiquitin Ligase by Qiu (2000)
10.1128/MCB.20.5.1825-1835.2000 / Mol. Cell. Biol. / Calcium depletion dissociates and activates heterodimeric Notch receptors by Rand (2000)
10.1074/jbc.274.51.36801 / J. Biol. Chem. / Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch by Ray (1999)
10.1073/pnas.96.6.3263 / Proc. Natl. Acad. Sci. USA / Evidence for a physical interaction between presenilin and Notch by Ray (1999)
10.1016/0092-8674(93)90423-N / Cell / Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor by Rebay (1993)
10.1038/71104 / Nature Neurosci. / Nuclear Notch1 signaling and the regulation of dendritic development by Redmond (2000)
10.1128/JVI.66.4.2594-2599.1992 / J. Virol. / Mouse mammary tumor gene int-3: A member of the Notch gene family transforms mammary epithelial cells by Robbins (1992)
10.1146/annurev.immunol.17.1.283 / Annu. Rev. Immunol. / Regulation of T cell fate by Notch [Review] by Robey (1999)
10.1038/364632a0 / Nature / Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats by Roehl (1993)
10.1126/science.273.5279.1227 / Science / Kuz, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis by Rooke (1996)
10.1002/(SICI)1521-1878(199803)20:3<209::AID-BIES4>3.0.CO;2-M / Bioessays / Positive and negative signals between interacting cells for establishing neural fate [Review] by Rooke (1998)
10.1006/dbio.1999.9483 / Dev. Biol. / A widespread and early requirement for a novel Notch function during Drosophila embryogenesis by Rusconi (1999)
10.1615/CritRevImmunol.v18.i4.40 / Crit. Rev. Immunol. / Positive and negative thymocyte selection by Saito (1998)
10.1128/JVI.72.7.6034-6039.1998 / J. Virol. / Functional replacement of the intracellular region of the Notch1 receptor by Epstein-Barr virus nuclear antigen 2 by Sakai (1998)
10.1016/S0168-0102(96)01110-8 / Neurosci. Res. / Cell-cell interactions during neural development—Multiple types of lateral inhibitions involved in Drosophila eye development [Review] by Sawamoto (1996)
10.1002/(SICI)1096-9861(20000306)418:2<121::AID-CNE1>3.0.CO;2-M / J. Comp. Neurol. / Development of neurogenic placodes in Xenopus laevis [Review] by Schlosser (2000)
10.1038/30756 / Nature / Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain by Schroeter (1998)
10.1006/dbio.1998.9014 / Dev. Biol. / Mastermind acts downstream of Notch to specify neuronal cell fates in the Drosophila central nervous system by Schuldt (1999)
10.1073/pnas.96.20.11382 / Proc. Natl. Acad. Sci. USA / Dominant-negative mutation in the beta 2 and beta 6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage by Schweisguth (1999)
10.1074/jbc.M005430200 / J. Biol. Chem. / Presenilin-1 and 2 are molecular targets for gamma secretase inhibitors by Seiffert (2000)
10.1016/S0959-4388(99)00054-9 / Curr. Opin. Neurobiol. / Notch and presenilins in vertebrates and invertebrates: Implications for neuronal development and degeneration [Review] by Selkoe (2000)
10.1126/science.286.5440.741 / Science / Contact-dependent inhibition of cortical neurite growth mediated by Notch signaling by Sestan (1999)
10.1006/dbio.1997.8723 / Dev. Biol. / Requirement For dynamin during Notch signaling In Drosophila neurogenesis by Seugnet (1997)
10.1242/dev.122.12.3765 / Development / Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway by Shawber (1996)
10.1093/genetics/81.1.143 / Genetics / Temperature-sensitive mutations of the Notch locus in Drosophila melanogaster by Shellenbarger (1975)
10.1016/0012-1606(78)90226-9 / Dev. Biol. / Temperature-sensitive periods and autonomy of pleiotropic effects of 1(1)Nts1, a conditional Notch lethal in Drosophila by Shellenbarger (1978)
10.1093/hmg/5.7.985 / Hum. Mol. Genet. / Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant by Sherrington (1996)
10.1038/375754a0 / Nature / Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease [see comments] by Sherrington (1995)
10.1074/jbc.274.46.32961 / J. Biol. Chem. / Mouse Jagged1 physically interacts with Notch2 and other Notch receptors—Assessment by quantitative methods by Shimizu (1999)
10.1242/dev.109.3.509 / Development / Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila [Review] by Simpson (1990)
10.1242/dev.124.23.4769 / Development / The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs by Sotillos (1997)
10.1038/ng1092-119 / Nature Genet. / Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins [published erratum appears in Nature Genet.2, 343, 1992] by Stifani (1992)
10.1128/JVI.74.4.1727-1735.2000 / J. Virol. / Activated Notch1 modulates gene expression in B cells similarly to Epstein-Barr viral nuclear antigen 2 by Strobl (2000)
10.1016/S0092-8674(00)81193-9 / Cell / Nuclear access and action of Notch in vivo by Struhl (1998)
10.1016/0092-8674(93)90424-O / Cell / Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo by Struhl (1993)
10.1038/19091 / Nature / Presenilin is required for activity and nuclear access of Notch in Drosophila by Struhl (1999)
10.1016/S0092-8674(00)80599-1 / Cell / Fundamentally different logic of gene regulation in eukaryotes and prokaryotes by Struhl (1999)
10.1242/dev.124.17.3439 / Development / Secreted forms of Delta and Serrate define antagonists of Notch signaling in Drosophila by Sun (1997)
10.1101/gad.8.6.707 / Genes Dev. / Notch1 is essential for postimplantation development in mice by Swiatek (1994)
10.1006/bbrc.1998.9799 / Biochem. Biophys. Res. Commun. / The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators by Tagami (1998)
10.1016/S0960-9822(95)00279-X / Curr. Biol. / Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-j-kappa/Su(H) by Tamura (1995)
10.1128/MCB.18.1.644 / Mol. Cell. Biol. / LIM protein Kyot2 negatively regulates transcription by association with the RBP-j DNA-binding protein by Taniguchi (1998)
10.1046/j.1440-169X.1998.t01-1-00001.x / Dev. Growth Differ. / Neural induction in embryos [Review] by Tiedemann (1998)
10.1242/dev.126.24.5725 / Development / Decoding vectorial information from a gradient: Sequential roles of the receptors Frizzled and Notch in establishing planar polarity in the Drosophila eye by Tomlinson (1999)
10.1073/pnas.96.18.10472 / Proc. Natl. Acad. Sci. USA / Distinct human Numb isoforms regulate differentiation vs. proliferation in the neuronal lineage by Verdi (1999)
10.1016/S0896-6273(00)80754-0 / Neuron / Numb localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to Notch-1 by Wakamatsu (1999)
10.1016/S0896-6273(00)80515-2 / Neuron / Notch receptor activation inhibits oligodendrocyte differentiation by Wang (1998)
10.1242/dev.124.22.4435 / Development / Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless by Wang (1997)
10.1006/mcne.1997.0612 / Mol. Cell. Neurosci. / The ins and outs of Notch signaling by Weinmaster (1997)
10.1016/S0959-437X(00)00097-6 / Curr. Opin. Genet. Dev. / Notch signal transduction: A real Rip and more [Review] by Weinmaster (2000)
10.1242/dev.124.23.4759 / Development / Sup-17, a Caenorhabditis elegans adam protein related to Drosophila Kuzbanian, and its role in Lin-12/Notch signalling by Wen (1997)
10.1128/MCB.19.8.5743 / Mol. Cell. Biol. / Notch and wingless regulate expression of cuticle patterning genes by Wesley (1999)
10.1074/jbc.275.13.9099 / J. Biol. Chem. / Notch responds differently to Delta and Wingless in cultured Drosophila cells by Wesley (2000)
10.1073/pnas.96.5.2497 / Proc. Natl. Acad. Sci. USA / Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling by Westlund (1999)
10.1021/bi991080q / Biochemistry / Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease by Wolfe (1999)
10.1021/bi982562p / Biochemistry / Peptidomimetic probes and molecular modeling suggest that Alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease by Wolfe (1999)
10.1038/19077 / Nature / Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity by Wolfe (1999)
10.1016/S0959-4388(99)00020-3 / Curr. Opin. Neurobiol. / Fringe: defining borders by regulating the Notch pathway by Wu (1999)
10.1038/19096 / Nature / Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants by Ye (1999)
10.1038/35024009 / Nature / A novel protein (Nicastrin) modulates presenilin-mediated Notch/Glp1 and APP processing by Yu (2000)
10.1016/S0960-9822(99)80211-5 / Curr. Biol. / An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila by Zecchini (1999)
10.1128/JVI.74.4.1939-1947.2000 / J. Virol. / A role for SKIP in EBNA2 activation of CBF1-repressed promoters by Zhou (2000)
10.1128/MCB.20.7.2400-2410.2000 / Mol. Cell. Biol. / SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC to facilitate NotchIC function by Zhou (2000)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 16, 2002, 11:45 a.m.)
Deposited	2 years, 4 months ago (April 3, 2023, 4:43 p.m.)
Indexed	2 weeks ago (Aug. 7, 2025, 4:50 a.m.)
Issued	24 years, 8 months ago (Dec. 1, 2000)
Published	24 years, 8 months ago (Dec. 1, 2000)
Published Print	24 years, 8 months ago (Dec. 1, 2000)

Funders 0

None

BibTeX

@article{Mumm_2000, title={Notch Signaling: From the Outside In}, volume={228}, ISSN={0012-1606}, url={http://dx.doi.org/10.1006/dbio.2000.9960}, DOI={10.1006/dbio.2000.9960}, number={2}, journal={Developmental Biology}, publisher={Elsevier BV}, author={Mumm, Jeffrey S. and Kopan, Raphael}, year={2000}, month=dec, pages={151–165} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        7
      ]
    ],
    "date-time": "2025-08-07T08:50:44Z",
    "timestamp": 1754556644602
  },
  "reference-count": 178,
  "publisher": "Elsevier BV",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2000,
            12,
            1
          ]
        ],
        "date-time": "2000-12-01T00:00:00Z",
        "timestamp": 975628800000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2013,
            7,
            17
          ]
        ],
        "date-time": "2013-07-17T00:00:00Z",
        "timestamp": 1374019200000
      },
      "content-version": "vor",
      "delay-in-days": 4611,
      "URL": "https://www.elsevier.com/open-access/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2000,
        12
      ]
    ]
  },
  "DOI": "10.1006/dbio.2000.9960",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        9,
        16
      ]
    ],
    "date-time": "2002-09-16T15:45:48Z",
    "timestamp": 1032191148000
  },
  "page": "151-165",
  "source": "Crossref",
  "is-referenced-by-count": 784,
  "title": "Notch Signaling: From the Outside In",
  "prefix": "10.1016",
  "volume": "228",
  "author": [
    {
      "given": "Jeffrey S.",
      "family": "Mumm",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Raphael",
      "family": "Kopan",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1006/dbio.2000.9960_RF1",
      "doi-asserted-by": "crossref",
      "first-page": "73",
      "DOI": "10.1016/0925-4773(95)00425-4",
      "article-title": "Involvement of Notch-1 in mammalian retinal neurogenesis\u2014Association of Notch-1 activity with both immature and terminally differentiated cells",
      "volume": "53",
      "author": "Ahmad",
      "year": "1995",
      "journal-title": "Mech. Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF2",
      "doi-asserted-by": "crossref",
      "first-page": "35269",
      "DOI": "10.1074/jbc.274.49.35269",
      "article-title": "c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads",
      "volume": "274",
      "author": "Akiyoshi",
      "year": "1999",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF3",
      "doi-asserted-by": "crossref",
      "first-page": "327",
      "DOI": "10.1006/scdb.1999.0292",
      "article-title": "Regulative development of the sea urchin embryo: Signalling cascades and morphogen gradients [Review]",
      "volume": "10",
      "author": "Angerer",
      "year": "1999",
      "journal-title": "Semin. Cell Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF4",
      "doi-asserted-by": "crossref",
      "first-page": "439",
      "DOI": "10.1016/S0166-2236(99)01455-1",
      "article-title": "Presenilins: Molecular switches between proteolysis and signal transduction [Review]",
      "volume": "22",
      "author": "Annaert",
      "year": "1999",
      "journal-title": "Trends Neurosci."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF5",
      "first-page": "325",
      "article-title": "Interactions between Wingless and Notch during the assignation of cell fates in Drosophila",
      "volume": "42",
      "author": "Arias",
      "year": "1998",
      "journal-title": "Int. J. Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF6",
      "doi-asserted-by": "crossref",
      "first-page": "770",
      "DOI": "10.1126/science.284.5415.770",
      "article-title": "Notch signaling: Cell fate control and signal integration in development [Review]",
      "volume": "284",
      "author": "Artavanis-Tsakonas",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF7",
      "doi-asserted-by": "crossref",
      "first-page": "125",
      "DOI": "10.1101/SQB.1994.059.01.016",
      "article-title": "Functional analysis of the TAN-1 gene, a human homolog of Drosophila Notch",
      "volume": "59",
      "author": "Aster",
      "year": "1994",
      "journal-title": "Cold Spring Harbor Symp. Quant. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF8",
      "doi-asserted-by": "crossref",
      "first-page": "11336",
      "DOI": "10.1074/jbc.272.17.11336",
      "article-title": "Oncogenic forms of Notch1 lacking either the primary binding site for RBP-j-kappa or nuclear localization sequences retain the ability to associate with RBP-j-kappa and activate transcription",
      "volume": "272",
      "author": "Aster",
      "year": "1997",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF9",
      "doi-asserted-by": "crossref",
      "first-page": "1826",
      "DOI": "10.1126/science.271.5257.1826",
      "article-title": "Interaction between Wingless and Notch signaling pathways mediated by dishevelled",
      "volume": "271",
      "author": "Axelrod",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF10",
      "doi-asserted-by": "crossref",
      "first-page": "264",
      "DOI": "10.1002/(SICI)1521-1878(200003)22:3<264::AID-BIES8>3.0.CO;2-M",
      "article-title": "Notch signaling in the nervous system. Pieces still missing from the puzzle",
      "volume": "22",
      "author": "Baker",
      "year": "2000",
      "journal-title": "Bioessays"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF11",
      "doi-asserted-by": "crossref",
      "first-page": "16434",
      "DOI": "10.1074/jbc.273.26.16434",
      "article-title": "Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription",
      "volume": "273",
      "author": "Baudino",
      "year": "1998",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF12",
      "doi-asserted-by": "crossref",
      "first-page": "125",
      "DOI": "10.1002/(SICI)1097-4547(19981015)54:2<125::AID-JNR1>3.0.CO;2-G",
      "article-title": "Notch and neurogenesis [Review]",
      "volume": "54",
      "author": "Beatus",
      "year": "1998",
      "journal-title": "J. Neurosci. Res."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF13",
      "doi-asserted-by": "crossref",
      "first-page": "175",
      "DOI": "10.1111/j.1600-065X.2000.imr017513.x",
      "article-title": "Microenvironmental influences on human B-cell development [Review]",
      "volume": "175",
      "author": "Bertrand",
      "year": "2000",
      "journal-title": "Immunol. Rev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF14",
      "doi-asserted-by": "crossref",
      "first-page": "499",
      "DOI": "10.1016/S0092-8674(00)81180-0",
      "article-title": "A Notch affair [Review]",
      "volume": "93",
      "author": "Bray",
      "year": "1998",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF15",
      "doi-asserted-by": "crossref",
      "first-page": "591",
      "DOI": "10.1006/scdb.1998.0262",
      "article-title": "Notch signalling in Drosophila: Three ways to use a pathway [Review]",
      "volume": "9",
      "author": "Bray",
      "year": "1998",
      "journal-title": "Semin. Cell Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF16",
      "doi-asserted-by": "crossref",
      "first-page": "707",
      "DOI": "10.1016/S0960-9822(99)80313-3",
      "article-title": "Repression by Notch is required before Wingless signalling during muscle progenitor cell development in Drosophila",
      "volume": "9",
      "author": "Brennan",
      "year": "1999",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF17",
      "doi-asserted-by": "crossref",
      "first-page": "210",
      "DOI": "10.1006/dbio.1999.9502",
      "article-title": "Wingless modulates the effects of dominant negative Notch molecules in the developing wing of Drosophila",
      "volume": "216",
      "author": "Brennan",
      "year": "1999",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF18",
      "doi-asserted-by": "crossref",
      "first-page": "177",
      "DOI": "10.1093/genetics/147.1.177",
      "article-title": "A functional analysis of Notch mutations in Drosophila",
      "volume": "147",
      "author": "Brennan",
      "year": "1997",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF19",
      "doi-asserted-by": "crossref",
      "first-page": "230",
      "DOI": "10.1006/dbio.1999.9501",
      "article-title": "The Abruptex mutations of Notch disrupt the establishment of proneural clusters in Drosophila",
      "volume": "216",
      "author": "Brennan",
      "year": "1999",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF20",
      "doi-asserted-by": "crossref",
      "first-page": "207",
      "DOI": "10.1016/S1097-2765(00)80417-7",
      "article-title": "A novel proteolytic cleavage involved in Notch signaling: The role of the distinigrin-metalloprotease TACE",
      "volume": "5",
      "author": "Brou",
      "year": "2000",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF21",
      "doi-asserted-by": "crossref",
      "first-page": "331",
      "DOI": "10.1016/S0092-8674(00)80213-5",
      "article-title": "The SREBP pathway\u2014Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor [Review]",
      "volume": "89",
      "author": "Brown",
      "year": "1997",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF22",
      "doi-asserted-by": "crossref",
      "first-page": "391",
      "DOI": "10.1016/S0092-8674(00)80675-3",
      "article-title": "Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans",
      "volume": "100",
      "author": "Brown",
      "year": "2000",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF23",
      "doi-asserted-by": "crossref",
      "first-page": "411",
      "DOI": "10.1038/35019075",
      "article-title": "Glycosyltransferase activity of Fringe modulates Notch-Delta interactions",
      "volume": "406",
      "author": "Bruckner",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF24",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1016/S0896-6273(00)80274-3",
      "article-title": "Numb diverts Notch pathway off the tramtrack [Review]",
      "volume": "17",
      "author": "Campos-Ortega",
      "year": "1996",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF25",
      "doi-asserted-by": "crossref",
      "first-page": "423",
      "DOI": "10.1016/S0092-8674(00)81583-4",
      "article-title": "Roles for proteolysis and trafficking in Notch maturation and signal transduction [Review]",
      "volume": "94",
      "author": "Chan",
      "year": "1998",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF26",
      "doi-asserted-by": "crossref",
      "first-page": "201",
      "DOI": "10.1016/S0896-6273(00)80771-0",
      "article-title": "Presenilins, processing of beta-amyloid precursor protein, and Notch signaling [Review]",
      "volume": "23",
      "author": "Chan",
      "year": "1999",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF27",
      "doi-asserted-by": "crossref",
      "first-page": "659",
      "DOI": "10.1016/0092-8674(93)90247-N",
      "article-title": "Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos",
      "volume": "73",
      "author": "Coffman",
      "year": "1993",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF28",
      "doi-asserted-by": "crossref",
      "first-page": "1533",
      "DOI": "10.1242/dev.121.5.1533",
      "article-title": "Notch1 is required for the coordinate segmentation of somites",
      "volume": "121",
      "author": "Conlon",
      "year": "1995",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF29",
      "doi-asserted-by": "crossref",
      "first-page": "567",
      "DOI": "10.1093/genetics/152.2.567",
      "article-title": "The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase",
      "volume": "152",
      "author": "Cornell",
      "year": "1999",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF30",
      "doi-asserted-by": "crossref",
      "first-page": "1579",
      "DOI": "10.1038/sj.onc.1201687",
      "article-title": "The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42",
      "volume": "16",
      "author": "Dahl",
      "year": "1998",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF31",
      "doi-asserted-by": "crossref",
      "first-page": "915",
      "DOI": "10.1083/jcb.127.4.915",
      "article-title": "Induction of mutant dynamin specifically blocks endocytic coated vesicle formation",
      "volume": "127",
      "author": "Damke",
      "year": "1994",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF32",
      "doi-asserted-by": "crossref",
      "first-page": "518",
      "DOI": "10.1038/19083",
      "article-title": "A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain",
      "volume": "398",
      "author": "De Strooper",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF33",
      "doi-asserted-by": "crossref",
      "first-page": "387",
      "DOI": "10.1038/34910",
      "article-title": "Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein",
      "volume": "391",
      "author": "De Strooper",
      "year": "1998",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF34",
      "doi-asserted-by": "crossref",
      "first-page": "166",
      "DOI": "10.1016/S0952-7915(99)00067-9",
      "article-title": "Notch signaling in T cell development [Review]",
      "volume": "12",
      "author": "Deftos",
      "year": "2000",
      "journal-title": "Curr. Opin. Immunol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF35",
      "doi-asserted-by": "crossref",
      "first-page": "954",
      "DOI": "10.1101/gad.13.8.954",
      "article-title": "ebi regulates epidermal growth factor receptor signaling pathways in Drosophila",
      "volume": "13",
      "author": "Dong",
      "year": "1999",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF36",
      "doi-asserted-by": "crossref",
      "first-page": "2801",
      "DOI": "10.1101/gad.13.21.2801",
      "article-title": "Mice lacking both presenilin genes exhibit early embryonic patterning defects",
      "volume": "13",
      "author": "Donoviel",
      "year": "1999",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF37",
      "doi-asserted-by": "crossref",
      "first-page": "3310",
      "DOI": "10.1128/MCB.14.5.3310",
      "article-title": "The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor",
      "volume": "14",
      "author": "Dou",
      "year": "1994",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF38",
      "doi-asserted-by": "crossref",
      "first-page": "7877",
      "DOI": "10.1073/pnas.97.14.7877",
      "article-title": "SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans",
      "volume": "97",
      "author": "Doyle",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF39",
      "doi-asserted-by": "crossref",
      "first-page": "649",
      "DOI": "10.1016/0092-8674(91)90111-B",
      "article-title": "TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms",
      "volume": "66",
      "author": "Ellisen",
      "year": "1991",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF40",
      "doi-asserted-by": "crossref",
      "first-page": "428",
      "DOI": "10.1038/35017062",
      "article-title": "Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1",
      "volume": "2",
      "author": "Esler",
      "year": "2000",
      "journal-title": "Nature Cell Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF41",
      "doi-asserted-by": "crossref",
      "first-page": "273",
      "DOI": "10.1016/0092-8674(94)90196-1",
      "article-title": "The suppressor of hairless protein participates in Notch receptor signaling",
      "volume": "79",
      "author": "Fortini",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF42",
      "doi-asserted-by": "crossref",
      "first-page": "555",
      "DOI": "10.1038/365555a0",
      "article-title": "An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye",
      "volume": "365",
      "author": "Fortini",
      "year": "1993",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF43",
      "doi-asserted-by": "crossref",
      "first-page": "1477",
      "DOI": "10.1093/genetics/150.4.1477",
      "article-title": "Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of Notch signaling",
      "volume": "150",
      "author": "Fostier",
      "year": "1998",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF44",
      "doi-asserted-by": "crossref",
      "first-page": "383",
      "DOI": "10.1016/S0896-6273(00)81171-X",
      "article-title": "rax, hes1, and Notch1 promote the formation of Muller glia by postnatal retinal progenitor cells",
      "volume": "26",
      "author": "Furukawa",
      "year": "2000",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF45",
      "doi-asserted-by": "crossref",
      "first-page": "395",
      "DOI": "10.1016/S0896-6273(00)81172-1",
      "article-title": "Radial glial identity is promoted by Notch1 signaling in the murine forebrain",
      "volume": "26",
      "author": "Gaiano",
      "year": "2000",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF46",
      "doi-asserted-by": "crossref",
      "first-page": "226",
      "DOI": "10.1002/(SICI)1096-9926(199910)60:4<226::AID-TERA7>3.0.CO;2-W",
      "article-title": "1998 Warkany Lecture: Signaling pathways in development",
      "volume": "60",
      "author": "Gerhart",
      "year": "1999",
      "journal-title": "Teratology"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF47",
      "doi-asserted-by": "crossref",
      "first-page": "2481",
      "DOI": "10.1242/dev.127.11.2481",
      "article-title": "aph-2 encodes a novel extracellular protein required for GLP-1-mediated signaling",
      "volume": "127",
      "author": "Goutte",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF48",
      "doi-asserted-by": "crossref",
      "first-page": "556",
      "DOI": "10.1016/0959-437X(94)90072-B",
      "article-title": "Structure/function studies of lin-12/Notch proteins [Review]",
      "volume": "4",
      "author": "Greenwald",
      "year": "1994",
      "journal-title": "Curr. Opin. Genet. Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF49",
      "doi-asserted-by": "crossref",
      "first-page": "1751",
      "DOI": "10.1101/gad.12.12.1751",
      "article-title": "Lin-12/Notch signaling\u2014Lessons from worms and flies [Review]",
      "volume": "12",
      "author": "Greenwald",
      "year": "1998",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF50",
      "doi-asserted-by": "crossref",
      "first-page": "271",
      "DOI": "10.1016/0092-8674(92)90470-W",
      "article-title": "Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells",
      "volume": "68",
      "author": "Greenwald",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF51",
      "doi-asserted-by": "crossref",
      "first-page": "103",
      "DOI": "10.1006/mcne.1997.0610",
      "article-title": "Notch signaling in vertebrate development and disease [Review]",
      "volume": "9",
      "author": "Gridley",
      "year": "1997",
      "journal-title": "Mol. Cell. Neurosci."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF52",
      "doi-asserted-by": "crossref",
      "first-page": "107",
      "DOI": "10.1007/BF00267238",
      "article-title": "Temperature-sensitive mutations in Drosophila melanogaster. XIV. A selection of immobile adults",
      "volume": "120",
      "author": "Grigliatti",
      "year": "1973",
      "journal-title": "Mol. Gen. Genet."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF53",
      "doi-asserted-by": "crossref",
      "first-page": "121",
      "DOI": "10.1016/S0925-4773(98)00071-9",
      "article-title": "Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb",
      "volume": "74",
      "author": "Hammond",
      "year": "1998",
      "journal-title": "Mech. Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF54",
      "doi-asserted-by": "crossref",
      "first-page": "1616",
      "DOI": "10.1182/blood.V95.5.1616.005k31_1616_1625",
      "article-title": "A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells",
      "volume": "95",
      "author": "Han",
      "year": "2000",
      "journal-title": "Blood"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF55",
      "doi-asserted-by": "crossref",
      "first-page": "466",
      "DOI": "10.1038/18979",
      "article-title": "Alzheimer's disease\u2014In search of gamma-secretase",
      "volume": "398",
      "author": "Hardy",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF56",
      "doi-asserted-by": "crossref",
      "first-page": "358",
      "DOI": "10.1006/dbio.1999.9477",
      "article-title": "Engineered truncations in the Drosophila mastermind protein disrupt Notch pathway function",
      "volume": "215",
      "author": "Helms",
      "year": "1999",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF57",
      "doi-asserted-by": "crossref",
      "first-page": "11872",
      "DOI": "10.1073/pnas.96.21.11872",
      "article-title": "Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency",
      "volume": "96",
      "author": "Herreman",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF58",
      "doi-asserted-by": "crossref",
      "first-page": "565",
      "DOI": "10.1083/jcb.122.3.565",
      "article-title": "Effects of mutant rat dynamin on endocytosis",
      "volume": "122",
      "author": "Herskovits",
      "year": "1993",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF59",
      "doi-asserted-by": "crossref",
      "first-page": "281",
      "DOI": "10.1046/j.1365-2567.2000.00073.x",
      "article-title": "T-cell regulation of peripheral tolerance and immunity: The potential role for Notch signalling [Review]",
      "volume": "100",
      "author": "Hoyne",
      "year": "2000",
      "journal-title": "Immunology"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF60",
      "doi-asserted-by": "crossref",
      "first-page": "23",
      "DOI": "10.1073/pnas.96.1.23",
      "article-title": "CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex",
      "volume": "96",
      "author": "Hsieh",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF61",
      "doi-asserted-by": "crossref",
      "first-page": "560",
      "DOI": "10.1126/science.7725102",
      "article-title": "Masking of the CBF1/RBPj\u03ba transcriptional repression domain by Epstein-Barr virus EBNA2",
      "volume": "268",
      "author": "Hsieh",
      "year": "1995",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF62",
      "doi-asserted-by": "crossref",
      "first-page": "3182",
      "DOI": "10.1101/gad.11.23.3182",
      "article-title": "Sel-10 a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the cdc4 family of proteins",
      "volume": "11",
      "author": "Hubbard",
      "year": "1997",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF63",
      "doi-asserted-by": "crossref",
      "first-page": "359",
      "DOI": "10.1093/genetics/145.2.359",
      "article-title": "Beaded of goldschmidt, an antimorphic allele of serrate, encodes a protein lacking transmembrane and intracellular domains",
      "volume": "145",
      "author": "Hukriede",
      "year": "1997",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF64",
      "doi-asserted-by": "crossref",
      "first-page": "966",
      "DOI": "10.1038/35016111",
      "article-title": "Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1",
      "volume": "405",
      "author": "Huppert",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF65",
      "doi-asserted-by": "crossref",
      "first-page": "355",
      "DOI": "10.1038/377355a0",
      "article-title": "Signalling downstream of activated mammalian Notch",
      "volume": "377",
      "author": "Jarriault",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF66",
      "doi-asserted-by": "crossref",
      "first-page": "345",
      "DOI": "10.1101/gad.6.3.345",
      "article-title": "Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands",
      "volume": "6",
      "author": "Jhappan",
      "year": "1992",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF67",
      "doi-asserted-by": "crossref",
      "first-page": "619",
      "DOI": "10.1006/scdb.1998.0261",
      "article-title": "Notch signalling pathway and human diseases [Review]",
      "volume": "9",
      "author": "Joutel",
      "year": "1998",
      "journal-title": "Semin. Cell Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF68",
      "doi-asserted-by": "crossref",
      "first-page": "191",
      "DOI": "10.1038/35012090",
      "article-title": "Fringe forms a complex with Notch",
      "volume": "405",
      "author": "Ju",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF69",
      "doi-asserted-by": "crossref",
      "first-page": "2269",
      "DOI": "10.1101/gad.12.15.2269",
      "article-title": "A histone deacetylase corepressor complex regulates the Notch signal transduction pathway",
      "volume": "12",
      "author": "Kao",
      "year": "1998",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF70",
      "doi-asserted-by": "crossref",
      "first-page": "4133",
      "DOI": "10.1242/dev.124.20.4133",
      "article-title": "Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives",
      "volume": "124",
      "author": "Kato",
      "year": "1997",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF71",
      "doi-asserted-by": "crossref",
      "first-page": "3728",
      "DOI": "10.1101/gad.12.23.3728",
      "article-title": "Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos",
      "volume": "12",
      "author": "Kidd",
      "year": "1998",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF72",
      "doi-asserted-by": "crossref",
      "first-page": "353",
      "DOI": "10.1016/S0968-0004(98)01263-8",
      "article-title": "Notch/Lin-12 signaling\u2014Transduction by regulated protein slicing",
      "volume": "23",
      "author": "Kimble",
      "year": "1998",
      "journal-title": "Trends Biochem. Sci."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF73",
      "doi-asserted-by": "crossref",
      "first-page": "333",
      "DOI": "10.1146/annurev.cellbio.13.1.333",
      "article-title": "The Lin-12/Notch signaling pathway and its regulation [Review]",
      "volume": "13",
      "author": "Kimble",
      "year": "1997",
      "journal-title": "Ann. Rev. Cell Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF74",
      "article-title": "Good things must come to an end: How is Notch signaling turned off?",
      "author": "Kopan",
      "year": "1999",
      "journal-title": "Perspective, STKE"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF75",
      "doi-asserted-by": "crossref",
      "DOI": "10.1101/gad.836900",
      "article-title": "A common enzyme connects Notch signaling with Alzheimer disease",
      "author": "Kopan",
      "year": "2000",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF76",
      "doi-asserted-by": "crossref",
      "first-page": "2385",
      "DOI": "10.1242/dev.120.9.2385",
      "article-title": "The intracellular domain of mouse Notch: A constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD",
      "volume": "120",
      "author": "Kopan",
      "year": "1994",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF77",
      "doi-asserted-by": "crossref",
      "first-page": "1683",
      "DOI": "10.1073/pnas.93.4.1683",
      "article-title": "Signal transduction by activated mNotch: Importance of proteolytic processing and its regulation by the extracellular domain",
      "volume": "93",
      "author": "Kopan",
      "year": "1996",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF78",
      "doi-asserted-by": "crossref",
      "first-page": "594",
      "DOI": "10.1016/S0959-4388(96)80090-0",
      "article-title": "The Notch pathway: Democracy and aristocracy in the selection of cell fate",
      "volume": "6",
      "author": "Kopan",
      "year": "1996",
      "journal-title": "Curr. Opin. Neurobiol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF79",
      "doi-asserted-by": "crossref",
      "first-page": "499",
      "DOI": "10.1083/jcb.97.2.499",
      "article-title": "Reversible blockage of membrane retrieval and endocytosis in the garland cell of the temperature-sensitive mutant of Drosophila melanogaster, shibirets1",
      "volume": "97",
      "author": "Kosaka",
      "year": "1983",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF80",
      "doi-asserted-by": "crossref",
      "first-page": "2117",
      "DOI": "10.1073/pnas.040556497",
      "article-title": "Notch signaling and the determination of appendage identity",
      "volume": "97",
      "author": "Kurata",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF81",
      "doi-asserted-by": "crossref",
      "first-page": "7238",
      "DOI": "10.1074/jbc.274.11.7238",
      "article-title": "Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis",
      "volume": "274",
      "author": "Kuroda",
      "year": "1999",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF82",
      "doi-asserted-by": "crossref",
      "first-page": "17211",
      "DOI": "10.1074/jbc.M000909200",
      "article-title": "Functional interaction between the mouse Notch1 intracellular region and histone acetyltransferases PCAF and GCN5",
      "volume": "275",
      "author": "Kurooka",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF83",
      "doi-asserted-by": "crossref",
      "first-page": "5448",
      "DOI": "10.1093/nar/26.23.5448",
      "article-title": "Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region",
      "volume": "26",
      "author": "Kurooka",
      "year": "1998",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF84",
      "doi-asserted-by": "crossref",
      "first-page": "2598",
      "DOI": "10.1101/gad.9.21.2598",
      "article-title": "The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling",
      "volume": "9",
      "author": "Lecourtois",
      "year": "1995",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF85",
      "doi-asserted-by": "crossref",
      "first-page": "771",
      "DOI": "10.1016/S0960-9822(98)70300-8",
      "article-title": "Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos",
      "volume": "8",
      "author": "Lecourtois",
      "year": "1998",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF86",
      "doi-asserted-by": "crossref",
      "first-page": "351",
      "DOI": "10.1038/377351a0",
      "article-title": "Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans s182 Alzheimers disease gene",
      "volume": "377",
      "author": "Levitan",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF87",
      "doi-asserted-by": "crossref",
      "first-page": "3599",
      "DOI": "10.1242/dev.125.18.3599",
      "article-title": "Effects of SEL-12 presenilin on LIN-12 localization and function in Caenorhabditis elegans",
      "volume": "125",
      "author": "Levitan",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF88",
      "doi-asserted-by": "crossref",
      "first-page": "583",
      "DOI": "10.1006/scdb.1998.0266",
      "article-title": "Notch signalling and the control of cell fate choices in vertebrates [Review]",
      "volume": "9",
      "author": "Lewis",
      "year": "1998",
      "journal-title": "Semin. Cell Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF89",
      "doi-asserted-by": "crossref",
      "first-page": "43",
      "DOI": "10.1016/S1074-7613(00)80457-4",
      "article-title": "The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32d cells through interaction with Notch1",
      "volume": "8",
      "author": "Li",
      "year": "1998",
      "journal-title": "Immunity"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF90",
      "doi-asserted-by": "crossref",
      "first-page": "12204",
      "DOI": "10.1073/pnas.94.22.12204",
      "article-title": "HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling",
      "volume": "94",
      "author": "Li",
      "year": "1997",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF91",
      "doi-asserted-by": "crossref",
      "first-page": "689",
      "DOI": "10.1038/35015085",
      "article-title": "Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1",
      "volume": "405",
      "author": "Li",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF92",
      "doi-asserted-by": "crossref",
      "first-page": "6138",
      "DOI": "10.1073/pnas.110126897",
      "article-title": "Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state",
      "volume": "97",
      "author": "Li",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF93",
      "doi-asserted-by": "crossref",
      "first-page": "1949",
      "DOI": "10.1101/gad.7.10.1949",
      "article-title": "Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei",
      "volume": "7",
      "author": "Lieber",
      "year": "1993",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF94",
      "doi-asserted-by": "crossref",
      "first-page": "2893",
      "DOI": "10.1242/dev.125.15.2893",
      "article-title": "A subset of Notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex",
      "volume": "125",
      "author": "Ligoxygakis",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF95",
      "doi-asserted-by": "crossref",
      "first-page": "2196",
      "DOI": "10.1101/gad.13.17.2196",
      "article-title": "The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling",
      "volume": "13",
      "author": "Luo",
      "year": "1999",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF96",
      "doi-asserted-by": "crossref",
      "first-page": "393",
      "DOI": "10.1002/(SICI)1097-4652(199912)181:3<393::AID-JCP3>3.0.CO;2-6",
      "article-title": "Arbiter of differentiation and death: Notch signaling meets apoptosis [Review]",
      "volume": "181",
      "author": "Miele",
      "year": "1999",
      "journal-title": "J. Cell. Physiol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF97",
      "doi-asserted-by": "crossref",
      "first-page": "369",
      "DOI": "10.1038/35019000",
      "article-title": "Fringe is a glycosyltransferase that modifies Notch",
      "volume": "406",
      "author": "Moloney",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF98",
      "doi-asserted-by": "crossref",
      "first-page": "377",
      "DOI": "10.1101/gad.14.3.377",
      "article-title": "Repression by Suppressor of Hairless and activation by Notch are required to define a single row of single-minde expressing cells in the Drosophila embryo",
      "volume": "14",
      "author": "Morel",
      "year": "2000",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF99",
      "doi-asserted-by": "crossref",
      "first-page": "499",
      "DOI": "10.1016/S0092-8674(00)80860-0",
      "article-title": "Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells",
      "volume": "101",
      "author": "Morrison",
      "year": "2000",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF100",
      "doi-asserted-by": "crossref",
      "first-page": "197",
      "DOI": "10.1016/S1097-2765(00)80416-5",
      "article-title": "A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1",
      "volume": "5",
      "author": "Mumm",
      "year": "2000",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF101",
      "doi-asserted-by": "crossref",
      "first-page": "415",
      "DOI": "10.1006/dbio.1994.1326",
      "article-title": "Delta-Notch signaling and Drosophila cell fate choice [Review]",
      "volume": "166",
      "author": "Muskavitch",
      "year": "1994",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF102",
      "doi-asserted-by": "crossref",
      "first-page": "33",
      "DOI": "10.1006/dbio.1999.9324",
      "article-title": "Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators",
      "volume": "213",
      "author": "Nellesen",
      "year": "1999",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF103",
      "doi-asserted-by": "crossref",
      "first-page": "412",
      "DOI": "10.1101/gad.13.4.412",
      "article-title": "Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor",
      "volume": "13",
      "author": "Nomura",
      "year": "1999",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF104",
      "doi-asserted-by": "crossref",
      "first-page": "2421",
      "DOI": "10.1242/dev.120.9.2421",
      "article-title": "An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells",
      "volume": "120",
      "author": "Nye",
      "year": "1994",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF105",
      "doi-asserted-by": "crossref",
      "first-page": "1621",
      "DOI": "10.1101/gad.12.11.1621",
      "article-title": "The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription",
      "volume": "12",
      "author": "Olave",
      "year": "1998",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF106",
      "doi-asserted-by": "crossref",
      "first-page": "2230",
      "DOI": "10.1128/MCB.18.4.2230",
      "article-title": "Notch inhibition of E47 supports the existence of a novel signaling pathway",
      "volume": "18",
      "author": "Ordentlich",
      "year": "1998",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF107",
      "doi-asserted-by": "crossref",
      "first-page": "609",
      "DOI": "10.1006/scdb.1998.0263",
      "article-title": "Modulators of Notch signaling [Review]",
      "volume": "9",
      "author": "Panin",
      "year": "1998",
      "journal-title": "Semin. Cell Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF108",
      "doi-asserted-by": "crossref",
      "first-page": "1373",
      "DOI": "10.1242/dev.127.7.1373",
      "article-title": "Ligand endocytosis drives receptor dissociation and activation in the Notch pathway",
      "volume": "127",
      "author": "Parks",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF109",
      "doi-asserted-by": "crossref",
      "first-page": "2283",
      "DOI": "10.1084/jem.183.5.2283",
      "article-title": "Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles",
      "volume": "183",
      "author": "Pear",
      "year": "1996",
      "journal-title": "J. Exp. Med."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF110",
      "doi-asserted-by": "crossref",
      "first-page": "215",
      "DOI": "10.1007/PL00000685",
      "article-title": "Determination of vertebrate retinal progenitor cell fate by the Notch pathway and basic helix-loop-helix transcription factors [Review]",
      "volume": "57",
      "author": "Perron",
      "year": "2000",
      "journal-title": "Cell. Mol. Life Sci."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF111",
      "doi-asserted-by": "crossref",
      "first-page": "364",
      "DOI": "10.1038/35012645",
      "article-title": "LAG-3 a putative transcriptional activator in the C. elegans Notch pathway",
      "volume": "405",
      "author": "Petcherski",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF112",
      "doi-asserted-by": "crossref",
      "first-page": "R471",
      "DOI": "10.1016/S0960-9822(00)00577-7",
      "article-title": "Mastermind is a putative activator for Notch",
      "volume": "10",
      "author": "Petcherski",
      "year": "2000",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF113",
      "doi-asserted-by": "crossref",
      "first-page": "464",
      "DOI": "10.1016/0012-1606(90)90212-2",
      "article-title": "shibire, a neurogenic mutant of Drosophila",
      "volume": "138",
      "author": "Poodry",
      "year": "1990",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF114",
      "doi-asserted-by": "crossref",
      "first-page": "133",
      "DOI": "10.1073/pnas.23.3.133",
      "article-title": "Chromosomal deficiencies and embryonic development of Drosophila melanogaster",
      "volume": "23",
      "author": "Poulson",
      "year": "1937",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF115",
      "doi-asserted-by": "crossref",
      "first-page": "91",
      "DOI": "10.1126/science.283.5398.91",
      "article-title": "Processing of the Notch ligand Delta by the metalloprotease Kuzbanian",
      "volume": "283",
      "author": "Qi",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF116",
      "doi-asserted-by": "crossref",
      "DOI": "10.1074/jbc.M007300200",
      "article-title": "Recognition and ubiquitination of Notch by Itch, a Hect-Type E3 Ubiquitin Ligase",
      "author": "Qiu",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF117",
      "doi-asserted-by": "crossref",
      "first-page": "1825",
      "DOI": "10.1128/MCB.20.5.1825-1835.2000",
      "article-title": "Calcium depletion dissociates and activates heterodimeric Notch receptors",
      "volume": "20",
      "author": "Rand",
      "year": "2000",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF118",
      "doi-asserted-by": "crossref",
      "first-page": "36801",
      "DOI": "10.1074/jbc.274.51.36801",
      "article-title": "Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch",
      "volume": "274",
      "author": "Ray",
      "year": "1999",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF119",
      "doi-asserted-by": "crossref",
      "first-page": "3263",
      "DOI": "10.1073/pnas.96.6.3263",
      "article-title": "Evidence for a physical interaction between presenilin and Notch",
      "volume": "96",
      "author": "Ray",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF120",
      "doi-asserted-by": "crossref",
      "first-page": "319",
      "DOI": "10.1016/0092-8674(93)90423-N",
      "article-title": "Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor",
      "volume": "74",
      "author": "Rebay",
      "year": "1993",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF121",
      "doi-asserted-by": "crossref",
      "first-page": "30",
      "DOI": "10.1038/71104",
      "article-title": "Nuclear Notch1 signaling and the regulation of dendritic development",
      "volume": "3",
      "author": "Redmond",
      "year": "2000",
      "journal-title": "Nature Neurosci."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF122",
      "doi-asserted-by": "crossref",
      "first-page": "2594",
      "DOI": "10.1128/JVI.66.4.2594-2599.1992",
      "article-title": "Mouse mammary tumor gene int-3: A member of the Notch gene family transforms mammary epithelial cells",
      "volume": "66",
      "author": "Robbins",
      "year": "1992",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF123",
      "doi-asserted-by": "crossref",
      "first-page": "283",
      "DOI": "10.1146/annurev.immunol.17.1.283",
      "article-title": "Regulation of T cell fate by Notch [Review]",
      "volume": "17",
      "author": "Robey",
      "year": "1999",
      "journal-title": "Annu. Rev. Immunol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF124",
      "doi-asserted-by": "crossref",
      "first-page": "632",
      "DOI": "10.1038/364632a0",
      "article-title": "Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats",
      "volume": "364",
      "author": "Roehl",
      "year": "1993",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF125",
      "doi-asserted-by": "crossref",
      "first-page": "1227",
      "DOI": "10.1126/science.273.5279.1227",
      "article-title": "Kuz, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis",
      "volume": "273",
      "author": "Rooke",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF126",
      "doi-asserted-by": "crossref",
      "first-page": "209",
      "DOI": "10.1002/(SICI)1521-1878(199803)20:3<209::AID-BIES4>3.0.CO;2-M",
      "article-title": "Positive and negative signals between interacting cells for establishing neural fate [Review]",
      "volume": "20",
      "author": "Rooke",
      "year": "1998",
      "journal-title": "Bioessays"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF127",
      "doi-asserted-by": "crossref",
      "first-page": "388",
      "DOI": "10.1006/dbio.1999.9483",
      "article-title": "A widespread and early requirement for a novel Notch function during Drosophila embryogenesis",
      "volume": "215",
      "author": "Rusconi",
      "year": "1999",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF128",
      "doi-asserted-by": "crossref",
      "first-page": "359",
      "DOI": "10.1615/CritRevImmunol.v18.i4.40",
      "article-title": "Positive and negative thymocyte selection",
      "volume": "18",
      "author": "Saito",
      "year": "1998",
      "journal-title": "Crit. Rev. Immunol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF129",
      "doi-asserted-by": "crossref",
      "first-page": "6034",
      "DOI": "10.1128/JVI.72.7.6034-6039.1998",
      "article-title": "Functional replacement of the intracellular region of the Notch1 receptor by Epstein-Barr virus nuclear antigen 2",
      "volume": "72",
      "author": "Sakai",
      "year": "1998",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF130",
      "doi-asserted-by": "crossref",
      "first-page": "205",
      "DOI": "10.1016/S0168-0102(96)01110-8",
      "article-title": "Cell-cell interactions during neural development\u2014Multiple types of lateral inhibitions involved in Drosophila eye development [Review]",
      "volume": "26",
      "author": "Sawamoto",
      "year": "1996",
      "journal-title": "Neurosci. Res."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF131",
      "doi-asserted-by": "crossref",
      "first-page": "121",
      "DOI": "10.1002/(SICI)1096-9861(20000306)418:2<121::AID-CNE1>3.0.CO;2-M",
      "article-title": "Development of neurogenic placodes in Xenopus laevis [Review]",
      "volume": "418",
      "author": "Schlosser",
      "year": "2000",
      "journal-title": "J. Comp. Neurol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF132",
      "doi-asserted-by": "crossref",
      "first-page": "382",
      "DOI": "10.1038/30756",
      "article-title": "Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain",
      "volume": "393",
      "author": "Schroeter",
      "year": "1998",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF133",
      "doi-asserted-by": "crossref",
      "first-page": "287",
      "DOI": "10.1006/dbio.1998.9014",
      "article-title": "Mastermind acts downstream of Notch to specify neuronal cell fates in the Drosophila central nervous system",
      "volume": "205",
      "author": "Schuldt",
      "year": "1999",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF134",
      "doi-asserted-by": "crossref",
      "first-page": "11382",
      "DOI": "10.1073/pnas.96.20.11382",
      "article-title": "Dominant-negative mutation in the beta 2 and beta 6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage",
      "volume": "96",
      "author": "Schweisguth",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF135",
      "doi-asserted-by": "crossref",
      "DOI": "10.1074/jbc.M005430200",
      "article-title": "Presenilin-1 and 2 are molecular targets for gamma secretase inhibitors",
      "author": "Seiffert",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF136",
      "doi-asserted-by": "crossref",
      "first-page": "50",
      "DOI": "10.1016/S0959-4388(99)00054-9",
      "article-title": "Notch and presenilins in vertebrates and invertebrates: Implications for neuronal development and degeneration [Review]",
      "volume": "10",
      "author": "Selkoe",
      "year": "2000",
      "journal-title": "Curr. Opin. Neurobiol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF137",
      "doi-asserted-by": "crossref",
      "first-page": "741",
      "DOI": "10.1126/science.286.5440.741",
      "article-title": "Contact-dependent inhibition of cortical neurite growth mediated by Notch signaling",
      "volume": "286",
      "author": "Sestan",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF138",
      "doi-asserted-by": "crossref",
      "first-page": "585",
      "DOI": "10.1006/dbio.1997.8723",
      "article-title": "Requirement For dynamin during Notch signaling In Drosophila neurogenesis",
      "volume": "192",
      "author": "Seugnet",
      "year": "1997",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF139",
      "doi-asserted-by": "crossref",
      "first-page": "3765",
      "DOI": "10.1242/dev.122.12.3765",
      "article-title": "Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway",
      "volume": "122",
      "author": "Shawber",
      "year": "1996",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF140",
      "doi-asserted-by": "crossref",
      "first-page": "143",
      "DOI": "10.1093/genetics/81.1.143",
      "article-title": "Temperature-sensitive mutations of the Notch locus in Drosophila melanogaster",
      "volume": "81",
      "author": "Shellenbarger",
      "year": "1975",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF141",
      "doi-asserted-by": "crossref",
      "first-page": "432",
      "DOI": "10.1016/0012-1606(78)90226-9",
      "article-title": "Temperature-sensitive periods and autonomy of pleiotropic effects of 1(1)Nts1, a conditional Notch lethal in Drosophila",
      "volume": "62",
      "author": "Shellenbarger",
      "year": "1978",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF142",
      "doi-asserted-by": "crossref",
      "first-page": "985",
      "DOI": "10.1093/hmg/5.7.985",
      "article-title": "Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant",
      "volume": "5",
      "author": "Sherrington",
      "year": "1996",
      "journal-title": "Hum. Mol. Genet."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF143",
      "doi-asserted-by": "crossref",
      "first-page": "754",
      "DOI": "10.1038/375754a0",
      "article-title": "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease [see comments]",
      "volume": "375",
      "author": "Sherrington",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF144",
      "doi-asserted-by": "crossref",
      "first-page": "32961",
      "DOI": "10.1074/jbc.274.46.32961",
      "article-title": "Mouse Jagged1 physically interacts with Notch2 and other Notch receptors\u2014Assessment by quantitative methods",
      "volume": "274",
      "author": "Shimizu",
      "year": "1999",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF145",
      "doi-asserted-by": "crossref",
      "first-page": "509",
      "DOI": "10.1242/dev.109.3.509",
      "article-title": "Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila [Review]",
      "volume": "109",
      "author": "Simpson",
      "year": "1990",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF146",
      "doi-asserted-by": "crossref",
      "first-page": "4769",
      "DOI": "10.1242/dev.124.23.4769",
      "article-title": "The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs",
      "volume": "124",
      "author": "Sotillos",
      "year": "1997",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF147",
      "doi-asserted-by": "crossref",
      "first-page": "119",
      "DOI": "10.1038/ng1092-119",
      "article-title": "Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins [published erratum appears in Nature Genet.2, 343, 1992]",
      "volume": "2",
      "author": "Stifani",
      "year": "1992",
      "journal-title": "Nature Genet."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF148",
      "doi-asserted-by": "crossref",
      "first-page": "1727",
      "DOI": "10.1128/JVI.74.4.1727-1735.2000",
      "article-title": "Activated Notch1 modulates gene expression in B cells similarly to Epstein-Barr viral nuclear antigen 2",
      "volume": "74",
      "author": "Strobl",
      "year": "2000",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF149",
      "doi-asserted-by": "crossref",
      "first-page": "649",
      "DOI": "10.1016/S0092-8674(00)81193-9",
      "article-title": "Nuclear access and action of Notch in vivo",
      "volume": "93",
      "author": "Struhl",
      "year": "1998",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF150",
      "doi-asserted-by": "crossref",
      "first-page": "331",
      "DOI": "10.1016/0092-8674(93)90424-O",
      "article-title": "Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo",
      "volume": "74",
      "author": "Struhl",
      "year": "1993",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF151",
      "doi-asserted-by": "crossref",
      "first-page": "522",
      "DOI": "10.1038/19091",
      "article-title": "Presenilin is required for activity and nuclear access of Notch in Drosophila",
      "volume": "398",
      "author": "Struhl",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF152",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1016/S0092-8674(00)80599-1",
      "article-title": "Fundamentally different logic of gene regulation in eukaryotes and prokaryotes",
      "volume": "98",
      "author": "Struhl",
      "year": "1999",
      "journal-title": "Cell"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF153",
      "doi-asserted-by": "crossref",
      "first-page": "3439",
      "DOI": "10.1242/dev.124.17.3439",
      "article-title": "Secreted forms of Delta and Serrate define antagonists of Notch signaling in Drosophila",
      "volume": "124",
      "author": "Sun",
      "year": "1997",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF154",
      "doi-asserted-by": "crossref",
      "first-page": "707",
      "DOI": "10.1101/gad.8.6.707",
      "article-title": "Notch1 is essential for postimplantation development in mice",
      "volume": "8",
      "author": "Swiatek",
      "year": "1994",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF155",
      "doi-asserted-by": "crossref",
      "first-page": "358",
      "DOI": "10.1006/bbrc.1998.9799",
      "article-title": "The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators",
      "volume": "253",
      "author": "Tagami",
      "year": "1998",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF156",
      "doi-asserted-by": "crossref",
      "first-page": "1416",
      "DOI": "10.1016/S0960-9822(95)00279-X",
      "article-title": "Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-j-kappa/Su(H)",
      "volume": "5",
      "author": "Tamura",
      "year": "1995",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF157",
      "doi-asserted-by": "crossref",
      "first-page": "644",
      "DOI": "10.1128/MCB.18.1.644",
      "article-title": "LIM protein Kyot2 negatively regulates transcription by association with the RBP-j DNA-binding protein",
      "volume": "18",
      "author": "Taniguchi",
      "year": "1998",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF158",
      "doi-asserted-by": "crossref",
      "first-page": "363",
      "DOI": "10.1046/j.1440-169X.1998.t01-1-00001.x",
      "article-title": "Neural induction in embryos [Review]",
      "volume": "40",
      "author": "Tiedemann",
      "year": "1998",
      "journal-title": "Dev. Growth Differ."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF159",
      "doi-asserted-by": "crossref",
      "first-page": "5725",
      "DOI": "10.1242/dev.126.24.5725",
      "article-title": "Decoding vectorial information from a gradient: Sequential roles of the receptors Frizzled and Notch in establishing planar polarity in the Drosophila eye",
      "volume": "126",
      "author": "Tomlinson",
      "year": "1999",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF160",
      "doi-asserted-by": "crossref",
      "first-page": "10472",
      "DOI": "10.1073/pnas.96.18.10472",
      "article-title": "Distinct human Numb isoforms regulate differentiation vs. proliferation in the neuronal lineage",
      "volume": "96",
      "author": "Verdi",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF161",
      "doi-asserted-by": "crossref",
      "first-page": "71",
      "DOI": "10.1016/S0896-6273(00)80754-0",
      "article-title": "Numb localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to Notch-1",
      "volume": "23",
      "author": "Wakamatsu",
      "year": "1999",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF162",
      "doi-asserted-by": "crossref",
      "first-page": "63",
      "DOI": "10.1016/S0896-6273(00)80515-2",
      "article-title": "Notch receptor activation inhibits oligodendrocyte differentiation",
      "volume": "21",
      "author": "Wang",
      "year": "1998",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF163",
      "doi-asserted-by": "crossref",
      "first-page": "4435",
      "DOI": "10.1242/dev.124.22.4435",
      "article-title": "Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless",
      "volume": "124",
      "author": "Wang",
      "year": "1997",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF164",
      "doi-asserted-by": "crossref",
      "first-page": "91",
      "DOI": "10.1006/mcne.1997.0612",
      "article-title": "The ins and outs of Notch signaling",
      "volume": "9",
      "author": "Weinmaster",
      "year": "1997",
      "journal-title": "Mol. Cell. Neurosci."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF165",
      "doi-asserted-by": "crossref",
      "first-page": "363",
      "DOI": "10.1016/S0959-437X(00)00097-6",
      "article-title": "Notch signal transduction: A real Rip and more [Review]",
      "volume": "10",
      "author": "Weinmaster",
      "year": "2000",
      "journal-title": "Curr. Opin. Genet. Dev."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF166",
      "doi-asserted-by": "crossref",
      "first-page": "4759",
      "DOI": "10.1242/dev.124.23.4759",
      "article-title": "Sup-17, a Caenorhabditis elegans adam protein related to Drosophila Kuzbanian, and its role in Lin-12/Notch signalling",
      "volume": "124",
      "author": "Wen",
      "year": "1997",
      "journal-title": "Development"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF167",
      "doi-asserted-by": "crossref",
      "first-page": "5743",
      "DOI": "10.1128/MCB.19.8.5743",
      "article-title": "Notch and wingless regulate expression of cuticle patterning genes",
      "volume": "19",
      "author": "Wesley",
      "year": "1999",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF168",
      "doi-asserted-by": "crossref",
      "first-page": "9099",
      "DOI": "10.1074/jbc.275.13.9099",
      "article-title": "Notch responds differently to Delta and Wingless in cultured Drosophila cells",
      "volume": "275",
      "author": "Wesley",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF169",
      "doi-asserted-by": "crossref",
      "first-page": "2497",
      "DOI": "10.1073/pnas.96.5.2497",
      "article-title": "Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling",
      "volume": "96",
      "author": "Westlund",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF170",
      "doi-asserted-by": "crossref",
      "first-page": "11223",
      "DOI": "10.1021/bi991080q",
      "article-title": "Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease",
      "volume": "38",
      "author": "Wolfe",
      "year": "1999",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF171",
      "doi-asserted-by": "crossref",
      "first-page": "4720",
      "DOI": "10.1021/bi982562p",
      "article-title": "Peptidomimetic probes and molecular modeling suggest that Alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease",
      "volume": "38",
      "author": "Wolfe",
      "year": "1999",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF172",
      "doi-asserted-by": "crossref",
      "first-page": "513",
      "DOI": "10.1038/19077",
      "article-title": "Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity",
      "volume": "398",
      "author": "Wolfe",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF173",
      "doi-asserted-by": "crossref",
      "first-page": "537",
      "DOI": "10.1016/S0959-4388(99)00020-3",
      "article-title": "Fringe: defining borders by regulating the Notch pathway",
      "volume": "9",
      "author": "Wu",
      "year": "1999",
      "journal-title": "Curr. Opin. Neurobiol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF174",
      "doi-asserted-by": "crossref",
      "first-page": "525",
      "DOI": "10.1038/19096",
      "article-title": "Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants",
      "volume": "398",
      "author": "Ye",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF175",
      "doi-asserted-by": "crossref",
      "DOI": "10.1038/35024009",
      "article-title": "A novel protein (Nicastrin) modulates presenilin-mediated Notch/Glp1 and APP processing",
      "author": "Yu",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1006/dbio.2000.9960_RF176",
      "doi-asserted-by": "crossref",
      "first-page": "460",
      "DOI": "10.1016/S0960-9822(99)80211-5",
      "article-title": "An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila",
      "volume": "9",
      "author": "Zecchini",
      "year": "1999",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF177",
      "doi-asserted-by": "crossref",
      "first-page": "1939",
      "DOI": "10.1128/JVI.74.4.1939-1947.2000",
      "article-title": "A role for SKIP in EBNA2 activation of CBF1-repressed promoters",
      "volume": "74",
      "author": "Zhou",
      "year": "2000",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1006/dbio.2000.9960_RF178",
      "doi-asserted-by": "crossref",
      "first-page": "2400",
      "DOI": "10.1128/MCB.20.7.2400-2410.2000",
      "article-title": "SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC to facilitate NotchIC function",
      "volume": "20",
      "author": "Zhou",
      "year": "2000",
      "journal-title": "Mol. Cell. Biol."
    }
  ],
  "container-title": "Developmental Biology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0012160600999603?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0012160600999603?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        4,
        3
      ]
    ],
    "date-time": "2023-04-03T20:43:51Z",
    "timestamp": 1680554631000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0012160600999603"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2000,
        12
      ]
    ]
  },
  "references-count": 178,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          2000,
          12
        ]
      ]
    }
  },
  "alternative-id": [
    "S0012160600999603"
  ],
  "URL": "http://dx.doi.org/10.1006/dbio.2000.9960",
  "relation": {},
  "ISSN": [
    "0012-1606"
  ],
  "subject": [],
  "container-title-short": "Developmental Biology",
  "published": {
    "date-parts": [
      [
        2000,
        12
      ]
    ]
  }
}