DOI: 10.1006/brcg.2001.1500. Neuronal Changes in Normal Human Aging and Alzheimer's Disease

Neuronal Changes in Normal Human Aging and Alzheimer's Disease

10.1006/brcg.2001.1500

Crossref journal-article

Elsevier BV

Brain and Cognition (78)

Bibliography

Uylings, H. B. M., & de Brabander, J. M. (2002). Neuronal Changes in Normal Human Aging and Alzheimerâs Disease. Brain and Cognition, 49(3), 268â276.

Authors 2

Harry B.M. Uylings (first)
J.M. de Brabander (additional)

References 42 Referenced 195

{'key': '10.1006/brcg.2001.1500_RF1', 'first-page': '209', 'article-title': "Deterioration threshold of synaptic morphology in aging and senile dementia of Alzheimer's type", 'volume': '18', 'author': 'Bertoni-Freddari', 'year': '1996', 'journal-title': 'Analytical and Quantitative Cytology and Histology'} / Analytical and Quantitative Cytology and Histology / Deterioration threshold of synaptic morphology in aging and senile dementia of Alzheimer's type by Bertoni-Freddari (1996)
10.1007/BF00308809 / Acta Neuropathology / Neuropathological stageing of Alzheimer-related changes by Braak (1991)
10.1002/cne.901020206 / Journal of Comparative Neurology / Organization of the cerebral cortex. III. A study of aging in the human cerebral cortex by Brody (1955)
10.1016/0006-8993(81)90436-4 / Brain Research / Quantitative evidence for selective dendritic growth in normal human aging but not in senile dementia by Buell (1981)
10.1097/00005072-198209000-00003 / Journal of Neuropathology and Experimental Neurology / Golgi-Cox and rapid Golgi methods as applied to autopsied human brain tissue: widely disparate results by Buell (1982)
10.1097/00001756-199401120-00032 / NeuroReport / Differential synaptic loss in the cortex in Alzheimer's disease: A study using archival material by Clinton (1994)
10.1046/j.1460-9568.1998.00137.x / European Journal of Neuroscience / Layer-specific dendritic regression of pyramidal cells with ageing in the human prefrontal cortex by De Brabander (1998)
10.1002/ana.410040410 / Annals of Neurology / Changes in brain weights during the span of human life: Relation of brain weights to body heights and body weights by Dekaban (1978)
10.1016/0006-8993(87)90028-X / Brain Research / Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia by De Ruiter (1987)
10.1016/0006-8993(87)90027-8 / Brain Research / Dendritic extent in human dentate gyrus granule cells in normal aging and senile dementia by Flood (1987)
10.1016/0006-8993(87)90744-X / Brain Research / Dendritic extent in human CA2-3 hippocampal pyramidal neurons in normal aging and senile dementia by Flood (1987)
10.1016/0006-8993(91)90494-G / Brain Research / Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. II. Subiculum by Flood (1991)
10.1523/JNEUROSCI.16-14-04491.1996 / Journal of Neuroscience / Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease by Gómez-Isla (1996)
10.1073/pnas.88.7.2845 / Proceedings of the National Academy of Sciences of the USA / Gender differences in age effect on brain atrophy measured by magnetic resonance imaging by Gur (1991)
10.1016/0006-8993(91)90493-F / Brain Research / Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. I. CA1 of hippocampus by Hanks (1991)
Heinsbroek, R. P. W.1995. The Netherlands Brain Bank and Alzheimer's disease (Research Report 94-01.) Amsterdam, NIBR [in Dutch].
10.1002/(SICI)1096-9861(19971006)386:4<661::AID-CNE11>3.0.CO;2-N / Journal of Comparative Neurology / Lifespan dendritic and spine changes in areas 10 and 18 of human cortex: A quantitative Golgi study by Jacobs (1997)
10.1002/cne.903270107 / Journal of Comparative Neurology / A quantitative dendritic analysis of Wernicke's area in humans. I. Lifespan changes by Jacobs (1993)
10.1212/WNL.43.1_Part_1.192 / Neurology / Quantitative synaptic alterations in the human neocortex during normal aging by Masliah (1993)
10.1111/j.1365-2990.1980.tb00283.x / Neuropathology and Applied Neurobiology / Variations with age in the volumes of grey and white matter in the cerebral hemisphere of man: Measurements with image analyzer by Miller (1980)
{'key': '10.1006/brcg.2001.1500_RF21', 'first-page': '85', 'article-title': 'Senile changes in the basal dendrites of the pyramidal cells in the human motor cortex: A quantitative Golgi study', 'volume': '24', 'author': 'Nakamura', 'year': '1984', 'journal-title': 'Clinical Neurology'} / Clinical Neurology / Senile changes in the basal dendrites of the pyramidal cells in the human motor cortex: A quantitative Golgi study by Nakamura (1984)
10.1007/BF00687009 / Acta Neuropathology / Age-related changes of pyramidal cell basal dendrites in layers III and V of human motor cortex: A quantitative Golgi study by Nakamura (1985)
10.1002/(SICI)1096-9861(19970728)384:2<312::AID-CNE10>3.0.CO;2-K / Journal of Comparative Neurology / Neocortical neuron number in human: Effect of sex and age by Pakkenberg (1997)
10.1016/S0079-6123(08)60707-4 / Progress in Brain Research / Central nervous system findings in a tenth decade autopsy population by Peress (1973)
{'key': '10.1006/brcg.2001.1500_RF25', 'series-title': 'Handbook of aging and cognition', 'first-page': '1', 'article-title': 'Aging of the brain and its impact on cognitive performance: Integration of structural and functional findings', 'author': 'Raz', 'year': '2000'} / Handbook of aging and cognition / Aging of the brain and its impact on cognitive performance: Integration of structural and functional findings by Raz (2000)
10.1093/cercor/7.3.268 / Cerebral Cortex / Selective aging of human cerebral cortex observed in vitro: Differential vulnerability of the prefrontal gray matter by Raz (1997)
10.1016/0197-4580(94)90030-2 / Neurobiology of Aging / No global neocortical nerve cell loss in brains from patients with senile dementia of Alzheimer's type by Regeur (1994)
10.1016/S0304-3940(00)01067-3 / Neuroscience Letters / Unbiased whole-brain analysis of gray matter loss in Alzheimer's disease by Rombouts (2000)
10.1016/0014-4886(75)90072-2 / Experimental Neurology / Progressive dendritic changes in aging human cortex by Scheibel (1975)
10.1016/0014-4886(76)90082-0 / Experimental Neurology / Progressive dendritic changes in aging human limbic system by Scheibel (1976)
10.1002/(SICI)1096-9861(19970324)379:4<482::AID-CNE2>3.0.CO;2-Z / Journal of Comparative Neurology / Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease by Simic (1997)
10.1016/S0079-6123(08)64447-7 / Progress in Brain Research / Sexual differentiation of the human brain: A historical perspective by Swaab (1984)
{'key': '10.1006/brcg.2001.1500_RF33', 'series-title': 'Molecular neuroanatomy techniques in the behavioral and neural sciences', 'first-page': '403', 'article-title': 'Potentialities and pitfalls in the use of human brain material in molecular neuroanatomy', 'author': 'Swaab', 'year': '1988'} / Molecular neuroanatomy techniques in the behavioral and neural sciences / Potentialities and pitfalls in the use of human brain material in molecular neuroanatomy by Swaab (1988)
10.1002/ana.410300410 / Annals of Neurology / Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment by Terry (1991)
10.1093/cercor/11.1.1 / Cerebral Cortex / Cortical change in Alzheimer's disease detected with a disease-specific population-based brain atlas by Thompson (2001)
10.1016/0165-0270(86)90116-0 / Journal of Neuroscience Methods / The metric analysis of three-dimensional dendritic tree patterns: A methodological review by Uylings (1986)
{'key': '10.1006/brcg.2001.1500_RF37', 'series-title': 'Neurodegenerative dementias: Clinical features and pathological mechanisms', 'first-page': '61', 'article-title': 'Neuronal and cellular changes in aging brain', 'author': 'Uylings', 'year': '2000'} / Neurodegenerative dementias: Clinical features and pathological mechanisms / Neuronal and cellular changes in aging brain by Uylings (2000)
Van der Loos, H. 1959, Dendro–dendritic junctions in the cerebral cortex. Ph.D. thesis, University of Amsterdam, Haarlem, Stam. [in Dutch]
10.1016/0197-4580(93)90113-P / Neurobiology of Aging / Regionally specific loss of neurons in the aging human hippocampus by West (1993)
10.1016/S0140-6736(94)92338-8 / Lancet / Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease by West (1994)
10.1097/00005072-197801000-00002 / Journal of Neuropathology and Experimental Neurology / The Golgi rapid method in clinical neuropathology: the morphologic consequences of suboptimal fixation by Williams (1978)
10.1016/S0079-6123(08)64297-1 / Progess in Brain Research / Age-related changes in Down syndrome brain and the cellular pathology of Alzheimer's disease by Williams (1986)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 16, 2002, 6:51 a.m.)
Deposited	5 years, 8 months ago (Dec. 16, 2019, 8:58 p.m.)
Indexed	8 hours, 12 minutes ago (Sept. 6, 2025, 3:21 p.m.)
Issued	23 years, 1 month ago (Aug. 1, 2002)
Published	23 years, 1 month ago (Aug. 1, 2002)
Published Print	23 years, 1 month ago (Aug. 1, 2002)

Funders 0

None

BibTeX

@article{Uylings_2002, title={Neuronal Changes in Normal Human Aging and Alzheimer’s Disease}, volume={49}, ISSN={0278-2626}, url={http://dx.doi.org/10.1006/brcg.2001.1500}, DOI={10.1006/brcg.2001.1500}, number={3}, journal={Brain and Cognition}, publisher={Elsevier BV}, author={Uylings, Harry B.M. and de Brabander, J.M.}, year={2002}, month=aug, pages={268–276} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        9,
        6
      ]
    ],
    "date-time": "2025-09-06T19:21:49Z",
    "timestamp": 1757186509526
  },
  "reference-count": 42,
  "publisher": "Elsevier BV",
  "issue": "3",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2002,
            8,
            1
          ]
        ],
        "date-time": "2002-08-01T00:00:00Z",
        "timestamp": 1028160000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2002,
        8
      ]
    ]
  },
  "DOI": "10.1006/brcg.2001.1500",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        9,
        16
      ]
    ],
    "date-time": "2002-09-16T10:51:07Z",
    "timestamp": 1032173467000
  },
  "page": "268-276",
  "source": "Crossref",
  "is-referenced-by-count": 195,
  "title": "Neuronal Changes in Normal Human Aging and Alzheimer's Disease",
  "prefix": "10.1016",
  "volume": "49",
  "author": [
    {
      "given": "Harry B.M.",
      "family": "Uylings",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "J.M.",
      "family": "de Brabander",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1006/brcg.2001.1500_RF1",
      "first-page": "209",
      "article-title": "Deterioration threshold of synaptic morphology in aging and senile dementia of Alzheimer's type",
      "volume": "18",
      "author": "Bertoni-Freddari",
      "year": "1996",
      "journal-title": "Analytical and Quantitative Cytology and Histology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF2",
      "doi-asserted-by": "crossref",
      "first-page": "239",
      "DOI": "10.1007/BF00308809",
      "article-title": "Neuropathological stageing of Alzheimer-related changes",
      "volume": "82",
      "author": "Braak",
      "year": "1991",
      "journal-title": "Acta Neuropathology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF3",
      "doi-asserted-by": "crossref",
      "first-page": "511",
      "DOI": "10.1002/cne.901020206",
      "article-title": "Organization of the cerebral cortex. III. A study of aging in the human cerebral cortex",
      "volume": "102",
      "author": "Brody",
      "year": "1955",
      "journal-title": "Journal of Comparative Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF4",
      "doi-asserted-by": "crossref",
      "first-page": "23",
      "DOI": "10.1016/0006-8993(81)90436-4",
      "article-title": "Quantitative evidence for selective dendritic growth in normal human aging but not in senile dementia",
      "volume": "214",
      "author": "Buell",
      "year": "1981",
      "journal-title": "Brain Research"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF5",
      "doi-asserted-by": "crossref",
      "first-page": "500",
      "DOI": "10.1097/00005072-198209000-00003",
      "article-title": "Golgi-Cox and rapid Golgi methods as applied to autopsied human brain tissue: widely disparate results",
      "volume": "41",
      "author": "Buell",
      "year": "1982",
      "journal-title": "Journal of Neuropathology and Experimental Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF6",
      "doi-asserted-by": "crossref",
      "first-page": "497",
      "DOI": "10.1097/00001756-199401120-00032",
      "article-title": "Differential synaptic loss in the cortex in Alzheimer's disease: A study using archival material",
      "volume": "5",
      "author": "Clinton",
      "year": "1994",
      "journal-title": "NeuroReport"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF7",
      "doi-asserted-by": "crossref",
      "first-page": "1261",
      "DOI": "10.1046/j.1460-9568.1998.00137.x",
      "article-title": "Layer-specific dendritic regression of pyramidal cells with ageing in the human prefrontal cortex",
      "volume": "10",
      "author": "De Brabander",
      "year": "1998",
      "journal-title": "European Journal of Neuroscience"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF8",
      "doi-asserted-by": "crossref",
      "first-page": "345",
      "DOI": "10.1002/ana.410040410",
      "article-title": "Changes in brain weights during the span of human life: Relation of brain weights to body heights and body weights",
      "volume": "4",
      "author": "Dekaban",
      "year": "1978",
      "journal-title": "Annals of Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF9",
      "doi-asserted-by": "crossref",
      "first-page": "217",
      "DOI": "10.1016/0006-8993(87)90028-X",
      "article-title": "Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia",
      "volume": "402",
      "author": "De Ruiter",
      "year": "1987",
      "journal-title": "Brain Research"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF10",
      "doi-asserted-by": "crossref",
      "first-page": "205",
      "DOI": "10.1016/0006-8993(87)90027-8",
      "article-title": "Dendritic extent in human dentate gyrus granule cells in normal aging and senile dementia",
      "volume": "402",
      "author": "Flood",
      "year": "1987",
      "journal-title": "Brain Research"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF11",
      "doi-asserted-by": "crossref",
      "first-page": "88",
      "DOI": "10.1016/0006-8993(87)90744-X",
      "article-title": "Dendritic extent in human CA2-3 hippocampal pyramidal neurons in normal aging and senile dementia",
      "volume": "409",
      "author": "Flood",
      "year": "1987",
      "journal-title": "Brain Research"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF12",
      "doi-asserted-by": "crossref",
      "first-page": "83",
      "DOI": "10.1016/0006-8993(91)90494-G",
      "article-title": "Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. II. Subiculum",
      "volume": "540",
      "author": "Flood",
      "year": "1991",
      "journal-title": "Brain Research"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF13",
      "doi-asserted-by": "crossref",
      "first-page": "4491",
      "DOI": "10.1523/JNEUROSCI.16-14-04491.1996",
      "article-title": "Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease",
      "volume": "16",
      "author": "G\u00f3mez-Isla",
      "year": "1996",
      "journal-title": "Journal of Neuroscience"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF14",
      "doi-asserted-by": "crossref",
      "first-page": "2845",
      "DOI": "10.1073/pnas.88.7.2845",
      "article-title": "Gender differences in age effect on brain atrophy measured by magnetic resonance imaging",
      "volume": "88",
      "author": "Gur",
      "year": "1991",
      "journal-title": "Proceedings of the National Academy of Sciences of the USA"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF15",
      "doi-asserted-by": "crossref",
      "first-page": "63",
      "DOI": "10.1016/0006-8993(91)90493-F",
      "article-title": "Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. I. CA1 of hippocampus",
      "volume": "540",
      "author": "Hanks",
      "year": "1991",
      "journal-title": "Brain Research"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF16",
      "unstructured": "Heinsbroek, R. P. W.1995. The Netherlands Brain Bank and Alzheimer's disease (Research Report 94-01.) Amsterdam, NIBR [in Dutch]."
    },
    {
      "key": "10.1006/brcg.2001.1500_RF17",
      "doi-asserted-by": "crossref",
      "first-page": "661",
      "DOI": "10.1002/(SICI)1096-9861(19971006)386:4<661::AID-CNE11>3.0.CO;2-N",
      "article-title": "Lifespan dendritic and spine changes in areas 10 and 18 of human cortex: A quantitative Golgi study",
      "volume": "386",
      "author": "Jacobs",
      "year": "1997",
      "journal-title": "Journal of Comparative Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF18",
      "doi-asserted-by": "crossref",
      "first-page": "83",
      "DOI": "10.1002/cne.903270107",
      "article-title": "A quantitative dendritic analysis of Wernicke's area in humans. I. Lifespan changes",
      "volume": "327",
      "author": "Jacobs",
      "year": "1993",
      "journal-title": "Journal of Comparative Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF19",
      "doi-asserted-by": "crossref",
      "first-page": "192",
      "DOI": "10.1212/WNL.43.1_Part_1.192",
      "article-title": "Quantitative synaptic alterations in the human neocortex during normal aging",
      "volume": "43",
      "author": "Masliah",
      "year": "1993",
      "journal-title": "Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF20",
      "doi-asserted-by": "crossref",
      "first-page": "119",
      "DOI": "10.1111/j.1365-2990.1980.tb00283.x",
      "article-title": "Variations with age in the volumes of grey and white matter in the cerebral hemisphere of man: Measurements with image analyzer",
      "volume": "6",
      "author": "Miller",
      "year": "1980",
      "journal-title": "Neuropathology and Applied Neurobiology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF21",
      "first-page": "85",
      "article-title": "Senile changes in the basal dendrites of the pyramidal cells in the human motor cortex: A quantitative Golgi study",
      "volume": "24",
      "author": "Nakamura",
      "year": "1984",
      "journal-title": "Clinical Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF22",
      "doi-asserted-by": "crossref",
      "first-page": "281",
      "DOI": "10.1007/BF00687009",
      "article-title": "Age-related changes of pyramidal cell basal dendrites in layers III and V of human motor cortex: A quantitative Golgi study",
      "volume": "65",
      "author": "Nakamura",
      "year": "1985",
      "journal-title": "Acta Neuropathology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF23",
      "doi-asserted-by": "crossref",
      "first-page": "312",
      "DOI": "10.1002/(SICI)1096-9861(19970728)384:2<312::AID-CNE10>3.0.CO;2-K",
      "article-title": "Neocortical neuron number in human: Effect of sex and age",
      "volume": "384",
      "author": "Pakkenberg",
      "year": "1997",
      "journal-title": "Journal of Comparative Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF24",
      "doi-asserted-by": "crossref",
      "first-page": "473",
      "DOI": "10.1016/S0079-6123(08)60707-4",
      "article-title": "Central nervous system findings in a tenth decade autopsy population",
      "volume": "40",
      "author": "Peress",
      "year": "1973",
      "journal-title": "Progress in Brain Research"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF25",
      "series-title": "Handbook of aging and cognition",
      "first-page": "1",
      "article-title": "Aging of the brain and its impact on cognitive performance: Integration of structural and functional findings",
      "author": "Raz",
      "year": "2000"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF26",
      "doi-asserted-by": "crossref",
      "first-page": "267",
      "DOI": "10.1093/cercor/7.3.268",
      "article-title": "Selective aging of human cerebral cortex observed in vitro: Differential vulnerability of the prefrontal gray matter",
      "volume": "7",
      "author": "Raz",
      "year": "1997",
      "journal-title": "Cerebral Cortex"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF27",
      "doi-asserted-by": "crossref",
      "first-page": "347",
      "DOI": "10.1016/0197-4580(94)90030-2",
      "article-title": "No global neocortical nerve cell loss in brains from patients with senile dementia of Alzheimer's type",
      "volume": "15",
      "author": "Regeur",
      "year": "1994",
      "journal-title": "Neurobiology of Aging"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF28",
      "doi-asserted-by": "crossref",
      "first-page": "231",
      "DOI": "10.1016/S0304-3940(00)01067-3",
      "article-title": "Unbiased whole-brain analysis of gray matter loss in Alzheimer's disease",
      "volume": "285",
      "author": "Rombouts",
      "year": "2000",
      "journal-title": "Neuroscience Letters"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF29",
      "doi-asserted-by": "crossref",
      "first-page": "392",
      "DOI": "10.1016/0014-4886(75)90072-2",
      "article-title": "Progressive dendritic changes in aging human cortex",
      "volume": "47",
      "author": "Scheibel",
      "year": "1975",
      "journal-title": "Experimental Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF30",
      "doi-asserted-by": "crossref",
      "first-page": "420",
      "DOI": "10.1016/0014-4886(76)90082-0",
      "article-title": "Progressive dendritic changes in aging human limbic system",
      "volume": "53",
      "author": "Scheibel",
      "year": "1976",
      "journal-title": "Experimental Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF31",
      "doi-asserted-by": "crossref",
      "first-page": "482",
      "DOI": "10.1002/(SICI)1096-9861(19970324)379:4<482::AID-CNE2>3.0.CO;2-Z",
      "article-title": "Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease",
      "volume": "379",
      "author": "Simic",
      "year": "1997",
      "journal-title": "Journal of Comparative Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF32",
      "doi-asserted-by": "crossref",
      "first-page": "361",
      "DOI": "10.1016/S0079-6123(08)64447-7",
      "article-title": "Sexual differentiation of the human brain: A historical perspective",
      "volume": "61",
      "author": "Swaab",
      "year": "1984",
      "journal-title": "Progress in Brain Research"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF33",
      "series-title": "Molecular neuroanatomy techniques in the behavioral and neural sciences",
      "first-page": "403",
      "article-title": "Potentialities and pitfalls in the use of human brain material in molecular neuroanatomy",
      "author": "Swaab",
      "year": "1988"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF34",
      "doi-asserted-by": "crossref",
      "first-page": "572",
      "DOI": "10.1002/ana.410300410",
      "article-title": "Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment",
      "volume": "30",
      "author": "Terry",
      "year": "1991",
      "journal-title": "Annals of Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF35",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1093/cercor/11.1.1",
      "article-title": "Cortical change in Alzheimer's disease detected with a disease-specific population-based brain atlas",
      "volume": "11",
      "author": "Thompson",
      "year": "2001",
      "journal-title": "Cerebral Cortex"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF36",
      "doi-asserted-by": "crossref",
      "first-page": "127",
      "DOI": "10.1016/0165-0270(86)90116-0",
      "article-title": "The metric analysis of three-dimensional dendritic tree patterns: A methodological review",
      "volume": "18",
      "author": "Uylings",
      "year": "1986",
      "journal-title": "Journal of Neuroscience Methods"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF37",
      "series-title": "Neurodegenerative dementias: Clinical features and pathological mechanisms",
      "first-page": "61",
      "article-title": "Neuronal and cellular changes in aging brain",
      "author": "Uylings",
      "year": "2000"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF38",
      "unstructured": "Van der Loos, H. 1959, Dendro\u2013dendritic junctions in the cerebral cortex. Ph.D. thesis, University of Amsterdam, Haarlem, Stam. [in Dutch]"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF39",
      "doi-asserted-by": "crossref",
      "first-page": "287",
      "DOI": "10.1016/0197-4580(93)90113-P",
      "article-title": "Regionally specific loss of neurons in the aging human hippocampus",
      "volume": "14",
      "author": "West",
      "year": "1993",
      "journal-title": "Neurobiology of Aging"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF40",
      "doi-asserted-by": "crossref",
      "first-page": "769",
      "DOI": "10.1016/S0140-6736(94)92338-8",
      "article-title": "Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease",
      "volume": "344",
      "author": "West",
      "year": "1994",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF41",
      "doi-asserted-by": "crossref",
      "first-page": "13",
      "DOI": "10.1097/00005072-197801000-00002",
      "article-title": "The Golgi rapid method in clinical neuropathology: the morphologic consequences of suboptimal fixation",
      "volume": "37",
      "author": "Williams",
      "year": "1978",
      "journal-title": "Journal of Neuropathology and Experimental Neurology"
    },
    {
      "key": "10.1006/brcg.2001.1500_RF42",
      "doi-asserted-by": "crossref",
      "first-page": "49",
      "DOI": "10.1016/S0079-6123(08)64297-1",
      "article-title": "Age-related changes in Down syndrome brain and the cellular pathology of Alzheimer's disease",
      "volume": "70",
      "author": "Williams",
      "year": "1986",
      "journal-title": "Progess in Brain Research"
    }
  ],
  "container-title": "Brain and Cognition",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0278262601915003?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0278262601915003?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2019,
        12,
        17
      ]
    ],
    "date-time": "2019-12-17T01:58:33Z",
    "timestamp": 1576547913000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0278262601915003"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2002,
        8
      ]
    ]
  },
  "references-count": 42,
  "journal-issue": {
    "issue": "3",
    "published-print": {
      "date-parts": [
        [
          2002,
          8
        ]
      ]
    }
  },
  "alternative-id": [
    "S0278262601915003"
  ],
  "URL": "http://dx.doi.org/10.1006/brcg.2001.1500",
  "relation": {},
  "ISSN": [
    "0278-2626"
  ],
  "subject": [],
  "container-title-short": "Brain and Cognition",
  "published": {
    "date-parts": [
      [
        2002,
        8
      ]
    ]
  }
}