DOI: 10.1006/bcmd.2002.0525. The Leukemia-Associated Gene Mllt1/ENL: Characterization of a Murine Homolog and Demonstration of an Essential Role in Embryonic Development

The Leukemia-Associated Gene Mllt1/ENL: Characterization of a Murine Homolog and Demonstration of an Essential Role in Embryonic Development

10.1006/bcmd.2002.0525

Crossref journal-article

Elsevier BV

Blood Cells, Molecules, and Diseases (78)

Bibliography

Doty, R. T., Vanasse, G. J., Disteche, C. M., & Willerford, D. M. (2002). The Leukemia-Associated Gene Mllt1/ENL: Characterization of a Murine Homolog and Demonstration of an Essential Role in Embryonic Development. Blood Cells, Molecules, and Diseases, 28(3), 407â417.

Authors 4

Raymond T. Doty (first)
Gary J. Vanasse (additional)
Christine M. Disteche (additional)
Dennis M. Willerford (additional)

References 37 Referenced 21

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10.1016/0092-8674(92)90603-A / Cell / The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene by Gu (1992)
10.1182/blood.V81.9.2386.2386 / Blood / Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome by Chen (1993)
10.1182/blood.V81.12.3197.3197 / Blood / HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities by Hunger (1993)
10.1093/emboj/18.13.3564 / EMBO J. / The Mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis by Dobson (1999)
{'key': '10.1006/bcmd.2002.0525_RF7', 'first-page': '377', 'article-title': 'Rearrangements involving chromosome band 11Q23 in acute leukaemia', 'volume': '4', 'author': 'Rowley', 'year': '1993', 'journal-title': 'Semin. Cancer Biol.'} / Semin. Cancer Biol. / Rearrangements involving chromosome band 11Q23 in acute leukaemia by Rowley (1993)
10.1073/pnas.90.18.8538 / Proc. Natl. Acad. Sci. USA / Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation by Corral (1993)
{'key': '10.1006/bcmd.2002.0525_RF9', 'first-page': '3085', 'article-title': 'MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13', 'volume': '8', 'author': 'Iida', 'year': '1993', 'journal-title': 'Oncogene'} / Oncogene / MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13 by Iida (1993)
10.1083/jcb.150.2.F45 / J. Cell Biol. / Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: Diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation by Aoyagi (2000)
10.1073/pnas.90.10.4631 / Proc. Natl. Acad. Sci. USA / Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs by Nakamura (1993)
10.1128/MCB.18.1.122 / Mol. Cell. Biol. / The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX by Slany (1998)
10.1182/blood.V84.6.1747.1747 / Blood / ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells by Rubnitz (1994)
10.1093/intimm/12.10.1397 / Int. Immunol. / Identification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse Btk by Kikuchi (2000)
10.1093/nar/25.17.3389 / Nucleic Acids Res. / Gapped BLAST and PSI-BLAST: A new generation of protein database search programs by Altschul (1997)
10.1182/blood.V93.9.3017 / Blood / Promoter element for transcription of unrearranged T-cell receptor β-chain gene in pro-T cells by Doty (1999)
10.1172/JCI6658 / J. Clin. Invest. / Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase by Vanasse (1999)
10.1016/1074-7613(95)90180-9 / Immunity / Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment by Willerford (1995)
10.1073/pnas.90.18.8424 / Proc. Natl. Acad. Sci. USA / Derivation of completely cell culture-derived mice from early-passage embryonic stem cells by Nagy (1993)
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{'key': '10.1006/bcmd.2002.0525_RF23', 'first-page': '229', 'article-title': 'Transcription from TATA-less promoters: Dihydrofolate reductase as a model', 'volume': '3', 'author': 'Azizkhan', 'year': '1993', 'journal-title': 'Crit. Rev. Eukaryot. Gene Expr.'} / Crit. Rev. Eukaryot. Gene Expr. / Transcription from TATA-less promoters: Dihydrofolate reductase as a model by Azizkhan (1993)
10.1038/sj.leu.2401534 / Leukemia / The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator by Schreiner (1999)
10.1038/sj.onc.1204108 / Oncogene / The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3 by Garcı́a-Cuéllar (2001)
10.1016/S0959-437X(99)80053-7 / Curr. Opin. Genet. Dev. / The trithorax-group and polycomb-group chromatin modifiers: Implications for disease by van Lohuizen (1999)
10.1093/nar/28.1.263 / Nucleic Acids Res. / The Pfam protein families database by Bateman (2000)
10.1016/S1097-2765(01)00325-2 / Mol. Cell / Identification of hTAF(II)80delta links apoptotic signaling pathways to transcription factor TFIID function by Bell (2001)
10.1128/MCB.18.12.7565 / Mol. Cell. Biol. / Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells by Marissen (1998)
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10.1093/genetics/160.3.1051 / Genetics / Genetic and molecular analysis of region 88E9;88F2 in Drosophila melanogaster, including the ear gene related to human factors involved in lineage-specific leukemias by Zraly (2002)

Dates

Type	When
Created	22 years, 10 months ago (Oct. 7, 2002, 3:22 p.m.)
Deposited	4 years, 3 months ago (May 26, 2021, 8:21 a.m.)
Indexed	3 weeks, 2 days ago (Aug. 12, 2025, 5:34 p.m.)
Issued	23 years, 4 months ago (May 1, 2002)
Published	23 years, 4 months ago (May 1, 2002)
Published Print	23 years, 4 months ago (May 1, 2002)

Funders 0

None

BibTeX

@article{Doty_2002, title={The Leukemia-Associated Gene Mllt1/ENL: Characterization of a Murine Homolog and Demonstration of an Essential Role in Embryonic Development}, volume={28}, ISSN={1079-9796}, url={http://dx.doi.org/10.1006/bcmd.2002.0525}, DOI={10.1006/bcmd.2002.0525}, number={3}, journal={Blood Cells, Molecules, and Diseases}, publisher={Elsevier BV}, author={Doty, Raymond T. and Vanasse, Gary J. and Disteche, Christine M. and Willerford, Dennis M.}, year={2002}, month=may, pages={407–417} }

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