DOI: 10.1002/pro.5560060319. Embedding strategies for effective use of information from multiple sequence alignments

Embedding strategies for effective use of information from multiple sequence alignments

10.1002/pro.5560060319

Crossref journal-article

Wiley

Protein Science (311)

Bibliography

Henikoff, S., & Henikoff, J. G. (1997). Embedding strategies for effective use of information from multiple sequence alignments. Protein Science, 6(3), 698â705. Portico.

Authors 2

Steven Henikoff (first)
Jorja G. Henikoff (additional)

References 43 Referenced 49

10.1016/S0022-2836(05)80360-2 / J Mol Biol / Basic local alignment search tool by Altschul (1990)
10.1073/pnas.87.14.5509 / Proc Natl Acad Sci USA / Protein database searches for multiple alignments by Altschul (1990)
10.1093/protein/7.7.841 / Protein Eng / PRINTS-A protein motif fingerprint database by Attwood (1994)
{'key': '10.1002/pro.5560060319-BIB4|cit4', 'first-page': '15', 'volume-title': 'The megaprior heuristic for discovering protein sequence patterns', 'author': 'Bailey', 'year': '1996'} / The megaprior heuristic for discovering protein sequence patterns by Bailey (1996)
10.1093/nar/20.suppl.2013 / Nucleic Acids Res / PROSITE: A dictionary of sites and patterns in proteins by Bairoch (1992)
10.1093/nar/20.suppl.2019 / Nucleic Acids Res / The SWISS-PROT protein sequence data bank by Bairoch (1992)
10.1038/ng0893-332 / Nature Gen / DbEST-Database for “expressed sequence tags” by Boguski (1993)
{'key': '10.1002/pro.5560060319-BIB8|cit8', 'first-page': '47', 'volume-title': 'Using Dirichlet mixture priors to derive hidden Markov models for protein families', 'author': 'Brown', 'year': '1993'} / Using Dirichlet mixture priors to derive hidden Markov models for protein families by Brown (1993)
10.1016/S0968-0004(00)89075-1 / Trends Biochem Sci / Protein splicing: Self-splicing of genetically mobile elements at the proteins level by Cooper (1995)
10.1016/S0959-440X(96)80056-X / Curr Opin Struct Biol / Hidden Markov models by Eddy (1996)
10.1016/0076-6879(90)83011-W / Methods Enzymol / Profile analysis by Gribskov (1990)
10.1073/pnas.84.13.4355 / Proc Natl Acad Sci USA / Profile analysis: Detection of distantly related proteins by Gribskov (1987)
10.1016/S0076-6879(96)66015-7 / Methods Enzymol / Identification of sequence patterns with profile analysis by Gribskov (1996)
{'key': '10.1002/pro.5560060319-BIB14|cit14', 'first-page': '135', 'article-title': 'Using substitution probabilities to improve position-specific scoring matrices', 'volume': '72', 'author': 'Henikoff', 'year': '1996', 'journal-title': 'CABIOS'} / CABIOS / Using substitution probabilities to improve position-specific scoring matrices by Henikoff (1996)
{'key': '10.1002/pro.5560060319-BIB15|cit15', 'first-page': '129', 'volume-title': 'Biotechnology Annual Review', 'volume': 'I', 'author': 'Henikoff', 'year': '1995'} / Biotechnology Annual Review by Henikoff (1995)
10.1073/pnas.85.18.6602 / Proc Natl Acad Sci USA / A large family of bacterial activator proteins by Henikoff (1988)
10.1093/nar/19.23.6565 / Nucleic Acids Res / Automated assembly of protein blocks for database searching by Henikoff (1991)
10.1073/pnas.89.22.10915 / Proc Natl Acad Sci USA / Amino acid substitution matrices from protein blocks by Henikoff (1992)
10.1002/prot.340170108 / Proteins Struct Fund Genet / Performance evaluation of amino acid substitution matrices by Henikoff (1993)
10.1016/0022-2836(94)90032-9 / J Mol Biol / Position-based sequence weights by Henikoff (1994)
{'key': '10.1002/pro.5560060319-BIB21|cit21', 'first-page': 'GC17', 'article-title': 'Automated construction and graphical presentation of protein blocks from unaligned sequences', 'volume': '763', 'author': 'Henikoff', 'year': '1995', 'journal-title': 'Gene'} / Gene / Automated construction and graphical presentation of protein blocks from unaligned sequences by Henikoff (1995)
10.1016/0076-6879(90)83009-X / Methods Enzymol / Finding protein similarities with nucleotide sequence databases by Henikoff (1990)
10.1006/jmbi.1994.1104 / J Mol Biol / Hidden Markov models in computational biology by Krogh (1994)
10.1002/pro.5560030118 / Protein Sci / Improving the sensitivity of the sequence profile method by Luthy (1994)
10.1006/jmbi.1994.1407 / J Mol Biol / Detecting patterns in protein sequences by Neuwald (1994)
10.1126/science.7624767 / Science / Bacterial genome sequence bagged by Nowak (1995)
10.1016/0022-2836(87)90200-2 / J Mol Biol / Detecting homology of distantly related proteins with consensus sequences by Patthy (1987)
10.1016/0076-6879(90)83007-V / Methods Enzymol / Rapid and sensitive sequence comparison with FASTP and FASTA by Pearson (1990)
10.1002/pro.5560040613 / Protein Sci / Comparison of methods for searching protein sequence databases by Pearson (1995)
10.1002/pro.5560031218 / Protein Sci / Conserved sequence features of inteins (protein introns) and their use in identifying new inteins and related proteins by Pietrokovski (1994)
10.1093/nar/24.19.3836 / Nucleic Acids Res / Searching databases of conserved sequence regions by aligning protein multiple-alignments by Pietrokovski (1996)
10.1093/nar/17.7.2421 / Nucleic Acids Res / Predictive motifs derived from cytosine methyltransferases by Posfai (1989)
{'key': '10.1002/pro.5560060319-BIB33|cit33', 'first-page': '327', 'article-title': 'Dirichlet mixtures: A method for improved detection of weak but significant protein sequence homology', 'volume': '72', 'author': 'Sjolander', 'year': '1996', 'journal-title': 'CABIOS'} / CABIOS / Dirichlet mixtures: A method for improved detection of weak but significant protein sequence homology by Sjolander (1996)
10.1073/pnas.87.1.118 / Proc Natl Acad Sci USA / Automatic generation of primary sequence patterns from sets of related protein sequences by Smith (1990)
10.1016/0022-2836(81)90087-5 / J Mol Biol / Identification of common molecular subsequences by Smith (1981)
10.1002/pro.5560030314 / Protein Sci / Modular arrangement of proteins as inferred from analysis of homology by Sonnhammer (1994)
10.1073/pnas.91.25.12091 / Proc Natl Acad Sci USA / Detection of conserved segments in proteins: Iterative scanning of sequence databases with alignment blocks by Tatusov (1994)
10.1093/nar/22.22.4673 / Nucleic Acids Res / CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice by Thompson (1994a)
{'key': '10.1002/pro.5560060319-BIB39|cit39', 'first-page': '19', 'article-title': 'Improved sensitivity of profile searches through the use of sequence weights and gap excision', 'volume': '70', 'author': 'Thompson', 'year': '1994b', 'journal-title': 'CABIOS'} / CABIOS / Improved sensitivity of profile searches through the use of sequence weights and gap excision by Thompson (1994b)
{'key': '10.1002/pro.5560060319-BIB40|cit40', 'first-page': '249', 'article-title': 'PATMAT: A searching and extraction program for sequence, pattern, and block queries and databases', 'volume': '8', 'author': 'Wallace', 'year': '1992', 'journal-title': 'CABIOS'} / CABIOS / PATMAT: A searching and extraction program for sequence, pattern, and block queries and databases by Wallace (1992)
10.1101/gr.5.2.173 / Genome Res / BEAUTY: An enhanced BLAST-based search tool that integrates multiple biological information resources into sequence similarity search results by Worley (1995)
{'key': '10.1002/pro.5560060319-BIB42|cit42', 'first-page': '109', 'article-title': 'Motif identification neural design for rapid and sensitive protein family search', 'volume': '72', 'author': 'Wu', 'year': '1996', 'journal-title': 'CABIOS'} / CABIOS / Motif identification neural design for rapid and sensitive protein family search by Wu (1996)
10.1002/pro.5560030818 / Protein Sci / Recognition of related proteins by iterative template refinement (ITR) by Yi (1994)

Dates

Type	When
Created	15 years, 1 month ago (July 12, 2010, 4:44 a.m.)
Deposited	4 years, 2 months ago (July 3, 2021, 9:27 p.m.)
Indexed	2 months ago (July 2, 2025, 10:40 a.m.)
Issued	28 years, 6 months ago (March 1, 1997)
Published	28 years, 6 months ago (March 1, 1997)
Published Online	16 years, 8 months ago (Dec. 31, 2008)
Published Print	28 years, 6 months ago (March 1, 1997)

Funders 1

NIH
Awards1
1. GM29009

BibTeX

@article{Henikoff_1997, title={Embedding strategies for effective use of information from multiple sequence alignments: Embedding strategies for database searching}, volume={6}, ISSN={0961-8368}, url={http://dx.doi.org/10.1002/pro.5560060319}, DOI={10.1002/pro.5560060319}, number={3}, journal={Protein Science}, publisher={Wiley}, author={Henikoff, Steven and Henikoff, Jorja G.}, year={1997}, month=mar, pages={698–705} }

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