DOI: 10.1002/path.1643. Keratins and skin disorders

10.1002/path.1643

Crossref journal-article

Wiley

The Journal of Pathology (311)

Abstract

AbstractThe association of keratin mutations with genetic skin fragility disorders is now one of the best‐established examples of cytoskeleton disorders. It has served as a paradigm for many other diseases and has been highly informative for the study of intermediate filaments and their associated components, in helping to understand the functions of this large family of structural proteins. The keratin diseases have shown unequivocally that, at least in the case of the epidermal keratins, a major function of intermediate filaments is to provide physical resilience for epithelial cells. This review article reflects on the variety of phenotypes arising from mutations in keratins and the reasons for this variation. Copyright © 2004 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

Bibliography

Lane, E., & McLean, W. (2004). Keratins and skin disorders. The Journal of Pathology, 204(4), 355â366. Portico.

Authors 2

EB Lane (first)
WHI McLean (additional)

References 93 Referenced 193

Dates

Type	When
Created	20 years, 10 months ago (Oct. 19, 2004, 3:15 p.m.)
Deposited	1 year, 11 months ago (Sept. 11, 2023, 12:38 p.m.)
Indexed	12 hours, 11 minutes ago (Aug. 29, 2025, 6:30 a.m.)
Issued	20 years, 10 months ago (Oct. 19, 2004)
Published	20 years, 10 months ago (Oct. 19, 2004)
Published Online	20 years, 10 months ago (Oct. 19, 2004)
Published Print	20 years, 9 months ago (Nov. 1, 2004)

Funders 0

None

BibTeX

@article{Lane_2004, title={Keratins and skin disorders}, volume={204}, ISSN={1096-9896}, url={http://dx.doi.org/10.1002/path.1643}, DOI={10.1002/path.1643}, number={4}, journal={The Journal of Pathology}, publisher={Wiley}, author={Lane, EB and McLean, WHI}, year={2004}, month=oct, pages={355–366} }

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    "10.1002/path.1643"
  ],
  "URL": "http://dx.doi.org/10.1002/path.1643",
  "relation": {},
  "ISSN": [
    "0022-3417",
    "1096-9896"
  ],
  "subject": [],
  "container-title-short": "The Journal of Pathology",
  "published": {
    "date-parts": [
      [
        2004,
        10,
        19
      ]
    ]
  },
  "assertion": [
    {
      "value": "2004-10-19",
      "order": 2,
      "name": "published",
      "label": "Published",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    }
  ]
}