Induction and axial patterning of the neural plate: Planar and vertical signals
10.1002/neu.480241004
Crossref journal-article
Wiley
Journal of Neurobiology (311)
Abstract

AbstractIn this review I summarize recent findings on the contributions of different cell groups to the formation of the basic plan of the nervous system of vertebrate embryos. Midline cells of the mesoderm—the organizer, notochord, and prechordal plate—and midline cells of the neural ectoderm—the notoplate and floor plate—appear to have a fundamental role in the induction and patterning of the neural plate. Vertical signals acting across tissue layers and planar signals acting through the neural epithelium have distinct roles and cooperate in induction and pattern formation. Whereas the prechordal plate and notochord have distinct vertical signaling properties, the initial anteroposterior (A‐P) pattern of the neural plate may be induced by planar signals originating from the organizer region. Planar signals from the notoplate may also contribute to the mediolateral (M‐L) patterning of the neural plate. These and other findings suggest a general view of neural induction and axial patterning. © 1993 John Wiley & Sons, Inc.

Bibliography

Altaba, A. R. i. (1993). Induction and axial patterning of the neural plate: Planar and vertical signals. Journal of Neurobiology, 24(10), 1276–1304. Portico.

Authors 1
  1. A. Rulz i Altaba (first)
References 222 Referenced 85
  1. 10.1111/j.1440-169X.1987.00535.x
  2. 10.1016/0092-8674(91)90616-7
  3. 10.1242/dev.118.1.139 / Development / Anterior mesendoderm induces mouse Engrailed genes in explant cultures by Ang S.‐L. (1993)
  4. 10.1242/dev.116.4.877 / Development / Notochord grafts do not suppress formation of neural crest or commissural neurons by Artinger K. B. (1992)
  5. 10.1016/0168-9525(91)90220-K
  6. 10.1073/pnas.88.15.6511
  7. 10.1073/pnas.89.8.3347
  8. 10.1002/jez.1400870303
  9. 10.1016/0092-8674(93)90249-P
  10. 10.1016/0092-8674(92)90632-M
  11. Bolce M. E.andHarland R. M.(1993). XFKH2 aXenopusHNF‐3α homologue exhibits both activin inducible and autonomous phases of expression in early embryos.Dev. Biol.(in press). (10.1006/dbio.1993.1317)
  12. {'key': 'e_1_2_1_13_1', 'first-page': '673', 'article-title': 'Ventral ectoderm of Xenopus forms neural tissue, including hindbrain, in response to activin', 'volume': '115', 'author': 'Bolce M. E.', 'year': '1992', 'journal-title': 'Development'} / Development / Ventral ectoderm of Xenopus forms neural tissue, including hindbrain, in response to activin by Bolce M. E. (1992)
  13. 10.1016/0168-9525(92)90234-U
  14. 10.1073/pnas.89.21.10056
  15. 10.1101/gad.7.1.13
  16. 10.1002/j.1460-2075.1992.tb05024.x
  17. 10.1101/gad.4.11.1910
  18. 10.1242/dev.112.2.499 / Development / Neuroanatomical and functional analysis of neural tube formation in notochordless Xenopus embryos: laterality of the spinal cord is lost by Clarke J. D. N. (1991)
  19. 10.1126/science.2402639
  20. {'key': 'e_1_2_1_21_1', 'first-page': '186', 'article-title': 'Induction and the organization of the body plan in Xenopus development', 'volume': '144', 'author': 'Cooke J.', 'year': '1989', 'journal-title': 'Cellular Basis of Morphogenesis. Ciba Foundation Symposium'} / Cellular Basis of Morphogenesis. Ciba Foundation Symposium / Induction and the organization of the body plan in Xenopus development by Cooke J. (1989)
  21. 10.1242/dev.102.1.85 / Development / The restrictive effect of early exposure to lithium upon body pattern in Xenopus development, studied by quantitative anatomy and immunofluorescence by Cooke J. (1988)
  22. 10.1242/dev.116.2.357
  23. 10.1242/dev.115.2.573
  24. 10.1242/dev.100.2.279
  25. 10.1002/aja.1001930411
  26. 10.1242/dev.111.2.287
  27. 10.1016/0092-8674(89)90954-9
  28. 10.1002/ar.1092280410
  29. 10.1101/gad.6.4.599
  30. 10.1242/dev.106.4.749
  31. 10.1126/science.1636091
  32. {'key': 'e_1_2_1_33_1', 'first-page': '211', 'article-title': 'Neural induction', 'volume': '75', 'author': 'Duprat A.‐M.', 'year': '1987', 'journal-title': 'Archs Anat. Micr. Morph. Exp.'} / Archs Anat. Micr. Morph. Exp. / Neural induction by Duprat A.‐M. (1987)
  33. 10.1038/340140a0
  34. 10.1002/neu.480210305
  35. 10.1101/gad.5.1.94
  36. 10.1126/science.1350865
  37. {'key': 'e_1_2_1_38_1', 'first-page': '179', 'article-title': 'Dynamic aspects of neural induction in amphibia experiments on Ambystoma mexicanum and Pleurodeles Waltii', 'volume': '65', 'author': 'Eyal‐Giladi H.', 'year': '1954', 'journal-title': 'J. Arch. Biol.'} / J. Arch. Biol. / Dynamic aspects of neural induction in amphibia experiments on Ambystoma mexicanum and Pleurodeles Waltii by Eyal‐Giladi H. (1954)
  38. 10.1242/dev.110.2.589 / Development / Isolation of the mouse Hox 2.9 gene: analysis of embryonic expression suggests that positional information along the anteroposterior axis is specified by mesoderm by Frohman M. A. (1989)
  39. 10.1016/B978-0-12-028609-6.50008-X
  40. 10.1242/dev.107.Supplement.37
  41. 10.1146/annurev.cb.02.110186.001221
  42. 10.1016/0012-1606(84)90042-3
  43. 10.1242/dev.111.2.523 / Development / Single cell analysis of mesoderm formation in the Xenopus embryo by Godsave S. F. (1991)
  44. 10.1242/dev.117.3.1001
  45. 10.1038/347391a0
  46. 10.1016/0092-8674(92)90550-V
  47. 10.1016/0922-3371(89)90006-3
  48. 10.1016/0922-3371(90)90105-6
  49. 10.1038/356157a0
  50. {'key': 'e_1_2_1_51_1', 'volume-title': 'The Heritage of Experimental Embryology. Hans Spemann and the Organizer', 'author': 'Hamburger V.', 'year': '1988'} / The Heritage of Experimental Embryology. Hans Spemann and the Organizer by Hamburger V. (1988)
  51. 10.1002/jmor.1050880104
  52. {'key': 'e_1_2_1_53_1', 'first-page': '221', 'volume-title': 'Organizer–A Milestone of a Half‐Century from Spemann', 'author': 'Hara K.', 'year': '1978'} / Organizer–A Milestone of a Half‐Century from Spemann by Hara K. (1978)
  53. 10.1038/350339a0
  54. 10.1016/0896-6273(89)90200-6
  55. 10.1002/cne.903280205
  56. 10.1242/dev.106.3.611 / Development / Expression of an engrailed‐related protein is induced in the anterior ectoderm of early Xenopus embryos by Hemmati‐Brivanlou A. (1989)
  57. 10.1038/359609a0
  58. 10.1126/science.1978411
  59. 10.1126/science.1987648
  60. 10.1038/359237a0
  61. 10.1242/dev.113.4.1159
  62. 10.1007/BF00656583
  63. 10.1007/BF00649865
  64. 10.1002/jez.1401060205
  65. {'key': 'e_1_2_1_66_1', 'first-page': '257', 'article-title': "Positional signalling by Hensen's node when grafted to the chick limb bud", 'volume': '94', 'author': 'Hornbruch A.', 'year': '1986', 'journal-title': 'J. Embryol. Exp. Morphol.'} / J. Embryol. Exp. Morphol. / Positional signalling by Hensen's node when grafted to the chick limb bud by Hornbruch A. (1986)
  66. {'key': 'e_1_2_1_67_1', 'first-page': '323', 'article-title': 'The development of the primary sensory neurons in Xenopus laevis (Daudin)', 'volume': '91', 'author': 'Hughes A. F.', 'year': '1957', 'journal-title': 'J. Anat. Lond.'} / J. Anat. Lond. / The development of the primary sensory neurons in Xenopus laevis (Daudin) by Hughes A. F. (1957)
  67. Hume C.andDodd J.(1993). Cwnt8c; a novel wnt gene with a potential role in primitive streak formation and hindbrain organization.Development(in press). (10.1242/dev.119.4.1147)
  68. {'key': 'e_1_2_1_69_1', 'first-page': '73', 'article-title': 'Motor nuclei, cranial nerve roots, and fiber pattern in the medulla oblongata after reversal experiments on the neural plate of Axolotl larvae. I. Bilateral operations', 'volume': '36', 'author': 'Jacobson C.‐O.', 'year': '1964', 'journal-title': 'Zool. Bidr. Uppsala Bd.'} / Zool. Bidr. Uppsala Bd. / Motor nuclei, cranial nerve roots, and fiber pattern in the medulla oblongata after reversal experiments on the neural plate of Axolotl larvae. I. Bilateral operations by Jacobson C.‐O. (1964)
  69. {'key': 'e_1_2_1_70_1', 'first-page': '233', 'volume-title': 'Morphogenesis and Pattern Formation', 'author': 'Jacobson A. G.', 'year': '1981'} / Morphogenesis and Pattern Formation by Jacobson A. G. (1981)
  70. 10.1002/jez.1401970205
  71. 10.1002/9780470513798.ch15
  72. {'key': 'e_1_2_1_73_1', 'first-page': '87', 'article-title': 'Floor plate‐derived signals and the control of neural cell pattern in vertebrates', 'volume': '86', 'author': 'Jessell T. M.', 'year': '1992', 'journal-title': 'Harvey Lecture Series'} / Harvey Lecture Series / Floor plate‐derived signals and the control of neural cell pattern in vertebrates by Jessell T. M. (1992)
  73. 10.1101/gad.6.3.345
  74. {'key': 'e_1_2_1_75_1', 'first-page': '785', 'article-title': 'Spatial aspects of neural induction in', 'volume': '107', 'author': 'Jones E. A.', 'year': '1989', 'journal-title': 'Xenopus laevis. Development'} / Xenopus laevis. Development / Spatial aspects of neural induction in by Jones E. A. (1989)
  75. 10.1242/dev.111.2.531 / Development / Involvement of bone morphogenetic protein 4 (BMP‐4) and Vgr‐1 in morphogenesis and neurogenesis in the mouse by Jones C. M. (1991)
  76. 10.1242/dev.115.2.639
  77. {'key': 'e_1_2_1_78_1', 'first-page': '222', 'article-title': 'Studies on the formation and state of determination of the trunk organizer in the newt, Cynops pyrhogster', 'volume': '187', 'author': 'Kaneda T.', 'year': '1979', 'journal-title': "Wilhelm Roux's Arch. Entw Mech. Org."} / Wilhelm Roux's Arch. Entw Mech. Org. / Studies on the formation and state of determination of the trunk organizer in the newt, Cynops pyrhogster by Kaneda T. (1979)
  78. 10.1016/0012-1606(88)90189-3
  79. {'key': 'e_1_2_1_80_1', 'first-page': '241', 'volume-title': 'Developmental Biology', 'author': 'Keller R.', 'year': '1985'} / Developmental Biology by Keller R. (1985)
  80. 10.1242/dev.103.1.193
  81. 10.1002/aja.1001930303
  82. 10.1002/aja.1001930302
  83. 10.1016/0896-6273(93)90328-O
  84. 10.1016/0092-8674(91)90574-I
  85. 10.1002/cne.900500109
  86. 10.1242/dev.113.4.1495 / Development / Hensen's node induced neural tissue in Xenopus ectoderm. Implications for the action of the organizer in neural induction by Kintner C. R. (1991)
  87. 10.1242/dev.99.3.311 / Development / Expression of the Xenopus N‐CAM RNA in ectoderm is an early response to neural induction by Kintner C. R. (1987)
  88. 10.1002/jez.1401120303
  89. 10.1016/0092-8674(92)90121-R
  90. 10.1016/0925-4773(92)90007-7
  91. Ku M.andMelton D. A.(1993). Xwnt11: a novel maternally expressedXenopuswnt gene.Development(in press). (10.1242/dev.119.4.1161)
  92. 10.1242/dev.117.1.105 / Development / Rhombomere transplantation repatterns the segmental organization of cranial nerves and reveals cell‐autonomous expression of a homeodomain protein by Kuratani S. C. (1993)
  93. 10.1101/gad.5.3.416
  94. 10.1002/cne.901890208
  95. 10.1242/dev.113.3.891
  96. 10.1163/002829670X00079
  97. 10.1016/0012-1606(88)90385-5
  98. 10.1016/0925-4773(92)90066-S
  99. 10.1038/337424a0
  100. 10.1007/BF01503740
  101. 10.1038/360737a0
  102. 10.1242/dev.115.2.371 / Development / Asymmetrical retinoic acid synthesis in the dorso‐ventral axis of the retina by McCaffery P. (1992)
  103. 10.1242/dev.115.2.463 / Development / Analysis of Xwnt4 in embryos of Xenopus laevis: a Wnt family member expressed in the brain and floor plate by McGrew L. L. (1992)
  104. 10.1016/0092-8674(90)90385-R
  105. 10.1016/0092-8674(92)90222-X
  106. 10.1016/0092-8674(89)90506-0
  107. 10.1002/j.1460-2075.1991.tb07849.x / EMBO J. / Effects of retinoic acid excess on expression of Hox2.9 and Krox20 and of morphological segmentation in the hindbrain of mouse embryos by Morris‐Kay G. M. (1991)
  108. 10.1016/B978-0-12-028609-6.50010-8
  109. 10.1007/BF00578701
  110. {'key': 'e_1_2_1_111_1', 'first-page': '149', 'article-title': 'The successive steps in the pattern formation of the amphibian central nervous system', 'volume': '32', 'author': 'Nieuwkoop P. D.', 'year': '1989', 'journal-title': 'Dev. Growth Diff.'} / Dev. Growth Diff. / The successive steps in the pattern formation of the amphibian central nervous system by Nieuwkoop P. D. (1989)
  111. 10.1111/j.1440-169X.1990.00023.x
  112. 10.1002/jez.1401200102
  113. {'key': 'e_1_2_1_114_1', 'volume-title': 'Normal Table of Xenopus laevis (Daudin)', 'author': 'Nieuwkoop P. D.', 'year': '1967'} / Normal Table of Xenopus laevis (Daudin) by Nieuwkoop P. D. (1967)
  114. {'key': 'e_1_2_1_115_1', 'volume-title': 'The Epigenetic Nature of Early Chordate Development. Inductive Interactions and Competence', 'author': 'Nieuwkoop P. D.', 'year': '1985'} / The Epigenetic Nature of Early Chordate Development. Inductive Interactions and Competence by Nieuwkoop P. D. (1985)
  115. 10.1016/0092-8674(92)90630-U
  116. 10.1002/jez.1400720304
  117. 10.1086/395697
  118. 10.1126/science.1990433
  119. 10.1016/0092-8674(92)90074-M
  120. 10.1016/0092-8674(89)90099-8
  121. {'key': 'e_1_2_1_122_1', 'first-page': '1145', 'article-title': 'Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos', 'volume': '113', 'author': 'Papalopulu N.', 'year': '1991', 'journal-title': 'Dev. Biol.'} / Dev. Biol. / Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos by Papalopulu N. (1991)
  122. 10.1242/dev.117.3.961
  123. 10.1016/0092-8674(89)90947-1
  124. 10.1242/dev.105.3.529 / Development / Peptidergic properties expressed in vitro by embryonic neuroblasts after neural induction by Pituello F. (1989)
  125. 10.1126/science.2237443
  126. 10.1242/dev.113.Supplement_2.105 / Development / Control of dorsoventral pattern in vertebrate neural development: induction and polarizing properties of the floor plate by Placzek M. (1991)
  127. 10.1242/dev.117.1.205 / Development / Induction of floor plate differentiation by contact‐dependent, homeogenetic signals by Placzek M. (1993)
  128. 10.1002/cne.902660210
  129. 10.1016/0012-1606(92)90076-S
  130. 10.1016/0925-4773(91)90068-H
  131. 10.1002/jez.1400990203
  132. 10.1242/dev.112.4.959 / Development / The L5 epitope: an early marker for neural induction in the chick embryo and its involvement in inductive interactions by Roberts C. (1991)
  133. 10.1101/gad.5.3.381
  134. 10.1002/ar.1092070214
  135. 10.1101/gad.5.8.1333
  136. 10.1242/dev.111.1.45
  137. 10.1242/dev.108.4.595 / Development / Neural expression of the Xenopus homeobox gene Xhox3: evidence for a patterning neural signal that spreads through the ectoderm by Ruiz I Altaba A. (1990)
  138. 10.1242/dev.116.1.67 / Development / Planar and vertical signals in the induction and patterning of the Xenopus nervous system by Ruiz I Altaba A. (1992)
  139. 10.1101/gad.5.2.175
  140. 10.1242/dev.112.4.945
  141. 10.1242/dev.116.1.81
  142. 10.1038/341033a0
  143. 10.1016/0168-9525(90)90075-H
  144. Ruiz I Altaba A. Cox C. Jessell T. M. andKlar A.(1993a). Ectopic neural expression of a floor plate marker in frog embryos injected with the midline transcription factorPintallaris. Proc. Natl. Acad. Sci. U.S.A.(in press). (10.1073/pnas.90.17.8268)
  145. Ruiz I Altaba A. Prezioso V. R. Darnell J. andJessell T. M.(1993b). Sequential expression of HNF ‐ 3β and HNF ‐ 3α by embryonic organizing centers: the dorsal lip/node notochord and floor plate.Mech. Dev.(in press). (10.1016/0925-4773(93)90060-B)
  146. 10.1016/0896-6273(92)90123-U
  147. 10.1016/0012-1606(90)90104-Q
  148. 10.1242/dev.118.1.47
  149. 10.1016/0012-1606(89)90096-1
  150. 10.1016/0012-1606(89)90307-2
  151. {'key': 'e_1_2_1_152_1', 'first-page': '21', 'article-title': 'Neural induction', 'volume': '33', 'author': 'SaxéN L.', 'year': '1989', 'journal-title': 'Int. J. Dev. Biol.'} / Int. J. Dev. Biol. / Neural induction by SaxéN L. (1989)
  152. {'key': 'e_1_2_1_153_1', 'first-page': '514', 'article-title': 'The two‐gradient hypothesis of primary neural induction. The combined effects of two types of inductors mixed at different ratios', 'volume': '9', 'author': 'Saxén L.', 'year': '1961', 'journal-title': 'J. Embyol. Exp. Morphol.'} / J. Embyol. Exp. Morphol. / The two‐gradient hypothesis of primary neural induction. The combined effects of two types of inductors mixed at different ratios by Saxén L. (1961)
  153. {'key': 'e_1_2_1_154_1', 'volume-title': 'Primary Embryonic Induction', 'author': 'Saxén L.', 'year': '1962'} / Primary Embryonic Induction by Saxén L. (1962)
  154. 10.1002/jez.1402490305
  155. 10.1007/BF00315697
  156. 10.1242/dev.109.2.243
  157. 10.1242/dev.112.2.615
  158. 10.1016/S0012-1606(05)80008-9
  159. 10.1016/0896-6273(91)90262-X
  160. 10.1016/0925-4773(92)90028-I
  161. 10.1016/0092-8674(87)90333-3
  162. {'key': 'e_1_2_1_163_1', 'first-page': '765', 'article-title': 'The induction of anterior and posterior neural genes in', 'volume': '109', 'author': 'Sharpe C.', 'year': '1990', 'journal-title': 'Xenopus laevis. Development'} / Xenopus laevis. Development / The induction of anterior and posterior neural genes in by Sharpe C. (1990)
  163. 10.1038/346763a0
  164. 10.1101/gad.7.1.1
  165. 10.1101/gad.5.8.1321
  166. 10.1101/gad.4.6.932
  167. 10.1016/0092-8674(89)90413-3
  168. 10.1038/326197a0
  169. 10.1242/dev.99.1.3 / Development / A mesoderm‐inducing factor is produced by a Xenopus cell line by Smith J. C. (1987)
  170. 10.1016/0012-1606(83)90354-8
  171. {'key': 'e_1_2_1_172_1', 'first-page': '299', 'article-title': 'Dorsalization and neural induction: properties of the organizer in', 'volume': '78', 'author': 'Smith J. C.', 'year': '1983', 'journal-title': 'Xenopus laevis. J. Embryol. Exp. Morphol.'} / Xenopus laevis. J. Embryol. Exp. Morphol. / Dorsalization and neural induction: properties of the organizer in by Smith J. C. (1983)
  172. 10.1038/345729a0
  173. 10.1242/dev.111.1.245 / Development / Temporal and regional differences in the expression pattern of distinct retinoic acid receptor β transcripts in chick embryos by Smith S. M. (1991)
  174. 10.1016/0092-8674(91)90070-F
  175. 10.1038/361547a0
  176. 10.1016/0092-8674(91)90069-B
  177. 10.1038/351409a0
  178. 10.1007/BF01380646
  179. {'key': 'e_1_2_1_180_1', 'volume-title': 'Embryonic Development and Induction', 'author': 'Splemann H.', 'year': '1938'} / Embryonic Development and Induction by Splemann H. (1938)
  180. {'key': 'e_1_2_1_181_1', 'first-page': '599', 'article-title': 'Über Induktion von Embryonalanlangen durch Implantation artfremder Organisatoren', 'volume': '100', 'author': 'Spemann H.', 'year': '1924', 'journal-title': 'Wilhelm Roux Arch. Entz Mech. Org.'} / Wilhelm Roux Arch. Entz Mech. Org. / Über Induktion von Embryonalanlangen durch Implantation artfremder Organisatoren by Spemann H. (1924)
  181. 10.1002/jez.1401580103
  182. 10.1242/dev.110.4.1271 / Development / Epithelial scatter factor and development of the chick embryonic axis by Stern C. D. (1990)
  183. 10.1242/dev.114.3.729 / Development / Neural induction and regionalization of the chick embryo by Storey K. G. (1992)
  184. 10.1242/dev.114.4.841
  185. 10.1111/j.1440-169X.1984.00081.x
  186. 10.1101/gad.6.3.356
  187. 10.1073/pnas.89.21.10237
  188. {'key': 'e_1_2_1_189_1', 'first-page': '267', 'volume-title': 'Organizer‐A Milestone of Half a Century from Spemann', 'author': 'Takata K.', 'year': '1978'} / Organizer‐A Milestone of Half a Century from Spemann by Takata K. (1978)
  189. 10.1007/BF00576752
  190. 10.1038/336775a0
  191. 10.1038/346847a0
  192. 10.1016/0092-8674(90)90445-K
  193. {'key': 'e_1_2_1_194_1', 'first-page': '113', 'article-title': 'Retinoic acid and chick limb bud development', 'volume': '1', 'author': 'Tickle C.', 'year': '1991', 'journal-title': 'Dev. Suppl.'} / Dev. Suppl. / Retinoic acid and chick limb bud development by Tickle C. (1991)
  194. 10.1038/296564a0
  195. 10.1038/254199a0
  196. {'key': 'e_1_2_1_197_1', 'first-page': '91', 'volume-title': 'Organizer‐A Milestone of a Half‐Century from Spemann', 'author': 'Tiedemann H.', 'year': '1978'} / Organizer‐A Milestone of a Half‐Century from Spemann by Tiedemann H. (1978)
  197. {'key': 'e_1_2_1_198_1', 'first-page': 'XXX', 'volume-title': 'Organizer—A Milestone of a Half‐Century from Spemann', 'author': 'Toivonen S.', 'year': '1978'} / Organizer—A Milestone of a Half‐Century from Spemann by Toivonen S. (1978)
  198. 10.1126/science.159.3814.539
  199. {'key': 'e_1_2_1_200_1', 'first-page': '69', 'article-title': "Studies on the inductive action of the Hensen's node following its transplantation in ovo to the early chick blastoderm. II. Regionally specific induction of the node region of different ages", 'volume': '10', 'author': 'Tsung S. D.', 'year': '1965', 'journal-title': 'Acta Biol. Exp. Sinica.'} / Acta Biol. Exp. Sinica. / Studies on the inductive action of the Hensen's node following its transplantation in ovo to the early chick blastoderm. II. Regionally specific induction of the node region of different ages by Tsung S. D. (1965)
  200. {'key': 'e_1_2_1_201_1', 'first-page': '805', 'article-title': 'Experimental studies on the neural induction in Amphioxus', 'volume': '11', 'author': 'Tung T. C.', 'year': '1962', 'journal-title': 'Scientia Sinica'} / Scientia Sinica / Experimental studies on the neural induction in Amphioxus by Tung T. C. (1962)
  201. {'key': 'e_1_2_1_202_1', 'first-page': '1', 'article-title': 'The segmentation of the primitive neural tube in chick embryos (Gallus domesticus)', 'volume': '41', 'author': 'Vaage S.', 'year': '1969', 'journal-title': 'Advan. Anat. Embryol. Cell. Biol.'} / Advan. Anat. Embryol. Cell. Biol. / The segmentation of the primitive neural tube in chick embryos (Gallus domesticus) by Vaage S. (1969)
  202. {'key': 'e_1_2_1_203_1', 'first-page': '232', 'article-title': "Resultats de la greffe de noeud Hensen d'age different sur le blastoderme de poulet", 'volume': '159', 'author': 'Vakaet L.', 'year': '1965', 'journal-title': 'C. R. Séanc. Soc. Biol.'} / C. R. Séanc. Soc. Biol. / Resultats de la greffe de noeud Hensen d'age different sur le blastoderme de poulet by Vakaet L. (1965)
  203. 10.1007/BF00315839
  204. 10.1242/dev.107.4.793 / Development / Effects of the notochord on proliferation and differentiation in the neural tube of the chick embryo by Van Straaten H. W. M. (1989)
  205. 10.1007/BF01744261
  206. 10.1101/gad.7.3.355
  207. 10.1007/BF00649862
  208. 10.1007/BF00649863
  209. 10.1038/138125a0
  210. 10.1038/345819a0
  211. 10.1242/dev.116.1.55 / Development / Regional differences inretinoid release from embryonic neural tissue detected by an in vitro reporter assay by Wagner M. (1992)
  212. 10.1002/aja.1000950302
  213. 10.1016/0092-8674(90)90439-L
  214. 10.1242/dev.113.1.199 / Development / A homolog of Drosophila Notch expressed during mammalian development by Weinmaster G. (1991)
  215. 10.1242/dev.116.4.931 / Development / Notch2: a second mammalian Notch gene by Weinmaster G. (1993)
  216. 10.1016/0092-8674(87)90664-7
  217. 10.1016/S0022-5193(69)80016-0
  218. 10.1242/dev.110.3.653 / Development / Regulations in the induction of the organized neural system in amphibian embryos by Yamada T. (1990)
  219. 10.1016/0092-8674(93)90248-O
  220. 10.1016/0092-8674(91)90247-V
  221. 10.1016/0012-1606(81)90479-6
  222. Zimmerman K. Shih J. Bars J. Collazo A. andAnderson D. A.(1993). Xash3 a novelXenopus achaete‐scutehomolog provides an early marker of planar neural induction and position along the mediolateral axis of the neural plate.Development(in press). (10.1242/dev.119.1.221)
Dates
Type When
Created 20 years, 7 months ago (Dec. 31, 2004, 10:38 p.m.)
Deposited 1 year, 9 months ago (Oct. 24, 2023, 8:48 p.m.)
Indexed 2 weeks, 3 days ago (Aug. 6, 2025, 8:26 a.m.)
Issued 31 years, 10 months ago (Oct. 1, 1993)
Published 31 years, 10 months ago (Oct. 1, 1993)
Published Online 20 years, 10 months ago (Oct. 11, 2004)
Published Print 31 years, 10 months ago (Oct. 1, 1993)
Funders 0

None

@article{Altaba_1993, title={Induction and axial patterning of the neural plate: Planar and vertical signals}, volume={24}, ISSN={1097-4695}, url={http://dx.doi.org/10.1002/neu.480241004}, DOI={10.1002/neu.480241004}, number={10}, journal={Journal of Neurobiology}, publisher={Wiley}, author={Altaba, A. Rulz i}, year={1993}, month=oct, pages={1276–1304} }