Abstract
AbstractThirty‐six deep hepatic lesions of localized photocoagulation were induced in 11 pigs by means of a neodymium‐YAG laser. Laser applications of 80 W/10 sec (10.190 W/cm2) were transmitted through a handpiece coupled to a water‐cooling circulation system to protect the quartz fiber and positioned through an echo‐guided trocar. During irradiation, temperature was sufficient for vaporization up to 5 mm from the laser source and high enough for tumor cell kill at a 10‐mm distance (54°C/60 sec). Intraoperative ultrasound visualized increasing photocoagulation (12–18 mm), and further controls demonstrated an echo‐free core of vaporization progressively covered by increasing fibrosis, well demarcated from normal parenchyma. Microscopy revealed central coagulative necrosis marginated from the third day by a growing fibrosis. By day 20 immunoblasts and mast cells were in profusion in the lesion border, and by day 120 a fibrotic network had invaded the scar and confirmed healing free of complication. This technique is proposed for deep vaporization of disseminated hepatic metastases.
Bibliography
Godlewski, G., Rouy, S., Pignodel, C., OuldâSaid, H., Eledjam, J. J., Bourgeois, J. M., & Sambuc, P. (1988). Deep localized neodymium (Nd)âYAG laser photocoagulation in liver using a new water cooled and echoguided handpiece. Lasers in Surgery and Medicine, 8(5), 501â509. Portico.
References
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Dates
Type | When |
---|---|
Created | 18 years, 5 months ago (March 3, 2007, 5:58 a.m.) |
Deposited | 1 year, 10 months ago (Oct. 21, 2023, 7:33 a.m.) |
Indexed | 1 year, 10 months ago (Oct. 28, 2023, 10:08 a.m.) |
Issued | 37 years, 7 months ago (Jan. 1, 1988) |
Published | 37 years, 7 months ago (Jan. 1, 1988) |
Published Online | 19 years, 10 months ago (Oct. 19, 2005) |
Published Print | 37 years, 7 months ago (Jan. 1, 1988) |
@article{Godlewski_1988, title={Deep localized neodymium (Nd)‐YAG laser photocoagulation in liver using a new water cooled and echoguided handpiece}, volume={8}, ISSN={1096-9101}, url={http://dx.doi.org/10.1002/lsm.1900080509}, DOI={10.1002/lsm.1900080509}, number={5}, journal={Lasers in Surgery and Medicine}, publisher={Wiley}, author={Godlewski, G. and Rouy, S. and Pignodel, C. and Ould‐Said, H. and Eledjam, J. J. and Bourgeois, J. M. and Sambuc, P.}, year={1988}, month=jan, pages={501–509} }